KEGG   ENZYME: 1.14.13.74Help
Entry
EC 1.14.13.74               Enzyme                                 

Name
7-deoxyloganin 7-hydroxylase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
7-deoxyloganin,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)
Reaction(IUBMB)
7-deoxyloganin + NADPH + H+ + O2 = loganin + NADP+ + H2O [RN:R03556]
Reaction(KEGG)
R03556;
(other) R05832
Show
Substrate
7-deoxyloganin [CPD:C06071];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
loganin [CPD:C01433];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
A heme-thiolate protein (P-450).
History
EC 1.14.13.74 created 2002
Pathway
Monoterpenoid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Reference
1  [PMID:11524113]
  Authors
Katano N, Yamamoto H, Iio R, Inoue K.
  Title
7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures.
  Journal
Phytochemistry. 58 (2001) 53-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
335305-40-3
KEGG   REACTION: R03556Help
Entry
R03556                      Reaction                               

Name
7-deoxyloganin,NADPH:oxygen oxidoreductase (7a-hydroxylating)
Definition
Deoxyloganin + NADPH + H+ + Oxygen <=> Loganin + NADP+ + H2O
Equation
Reaction class
C00005_C00006
C01433_C06071
Enzyme
Pathway
Monoterpenoid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
DBGET integrated database retrieval system