KEGG   ENZYME: 1.6.5.7Help
Entry
EC 1.6.5.7                  Enzyme                                 

Name
2-hydroxy-1,4-benzoquinone reductase;
hydroxybenzoquinone reductase;
1,2,4-trihydroxybenzene:NAD oxidoreductase
Class
Oxidoreductases;
Acting on NADH or NADPH;
With a quinone or similar compound as acceptor
BRITE hierarchy
Sysname
NADH:2-hydroxy-1,4-benzoquinone oxidoreductase
Reaction(IUBMB)
2-hydroxy-1,4-benzoquinone + NADH + H+ = hydroxyquinol + NAD+ [RN:R05399]
Reaction(KEGG)
Substrate
2-hydroxy-1,4-benzoquinone [CPD:C07103];
NADH [CPD:C00004];
H+ [CPD:C00080]
Product
hydroxyquinol [CPD:C02814];
NAD+ [CPD:C00003]
Comment
A flavoprotein (FMN) that differs in substrate specificity from other quinone reductases. The enzyme in Burkholderia cepacia is inducible by 2,4,5-trichlorophenoxyacetate.
History
EC 1.6.5.7 created 2000, modified 2004
Pathway
Chlorocyclohexane and chlorobenzene degradation
Aminobenzoate degradation
Metabolic pathways
Microbial metabolism in diverse environments
Reference
1  [PMID:9721310]
  Authors
Zaborina O, Daubaras DL, Zago A, Xun L, Saido K, Klem T, Nikolic D, Chakrabarty AM.
  Title
Novel pathway for conversion of chlorohydroxyquinol to maleylacetate in Burkholderia cepacia AC1100.
  Journal
J. Bacteriol. 180 (1998) 4667-75.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
214466-94-1
KEGG   REACTION: R05399Help
Entry
R05399                      Reaction                               

Name
NADH:2-hydroxy-1,4-benzoquinone oxidoreductase
Definition
2-Hydroxy-1,4-benzoquinone + NADH + H+ <=> Benzene-1,2,4-triol + NAD+
Equation
Comment
hydroxybenzoquinone reductase
Reaction class
C00003_C00004
C02814_C07103
Enzyme
Pathway
Chlorocyclohexane and chlorobenzene degradation
Aminobenzoate degradation
Metabolic pathways
Microbial metabolism in diverse environments
KEGG   REACTION: R06853Help
Entry
R06853                      Reaction                               

Definition
Benzene-1,2,4-triol <=> 2-Hydroxy-1,4-benzoquinone
Equation
Comment
1,2,4-benzenetriol dehydrogenase
Reaction class
C02814_C07103
Enzyme
1.1.-.-
Pathway
Aminobenzoate degradation
Microbial metabolism in diverse environments
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