KEGG   ENZYME: 2.1.1.50Help
Entry
EC 2.1.1.50                 Enzyme                                 

Name
loganate O-methyltransferase;
loganate methyltransferase;
S-adenosyl-L-methionine:loganic acid methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:loganate 11-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + loganate = S-adenosyl-L-homocysteine + loganin [RN:R03554]
Reaction(KEGG)
R03554;
(other) R05834
Show
Substrate
S-adenosyl-L-methionine [CPD:C00019];
loganate [CPD:C01512]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
loganin [CPD:C01433]
Comment
Also acts on secologanate. Methylates the 11-carboxy group of the monoterpenoid loganate.
History
EC 2.1.1.50 created 1976
Pathway
Monoterpenoid biosynthesis
Biosynthesis of secondary metabolites
Reference
1  [PMID:4698228]
  Authors
Madyastha KM, Guarnaccia R, Baxter C, Coscia CJ.
  Title
S-Adenosyl-L-methionine: loganic acid methyltransferase. A carboxyl-alkylating enzyme from Vinca rosea.
  Journal
J. Biol. Chem. 248 (1973) 2497-501.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
39391-10-1
KEGG   REACTION: R03554Help
Entry
R03554                      Reaction                               

Name
S-Adenosyl-L-methionine:loganate 11-O-methyltransferase
Definition
S-Adenosyl-L-methionine + Loganate <=> S-Adenosyl-L-homocysteine + Loganin
Equation
Comment
irreversible
Reaction class
C00019_C00021
C01433_C01512
Enzyme
Pathway
Monoterpenoid biosynthesis
Biosynthesis of secondary metabolites
DBGET integrated database retrieval system