KEGG   ENZYME: 5.4.99.14Help
Entry
EC 5.4.99.14                Enzyme                                 

Name
4-carboxymethyl-4-methylbutenolide mutase;
4-methyl-2-enelactone isomerase;
4-methylmuconolactone methylisomerase;
4-methyl-3-enelactone methyl isomerase
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
BRITE hierarchy
Sysname
4-carboxymethyl-4-methylbut-2-en-1,4-olide methylmutase
Reaction(IUBMB)
4-carboxymethyl-4-methylbut-2-en-1,4-olide = 4-carboxymethyl-3-methylbut-2-en-1,4-olide [RN:R04510]
Reaction(KEGG)
Substrate
4-carboxymethyl-4-methylbut-2-en-1,4-olide [CPD:C04559]
Product
4-carboxymethyl-3-methylbut-2-en-1,4-olide [CPD:C04558]
History
EC 5.4.99.14 created 1992
Pathway
Toluene degradation
Microbial metabolism in diverse environments
Reference
1
  Authors
Bruce, N.C. and Cain, R.B.
  Title
beta-Methylmuconolactone, a key intermediate in the dissimilation of methylaromatic compounds by a modified 3-oxoadipate pathway evolved in nocardioform actinomycetes.
  Journal
FEMS Microbiol. Lett. 50 (1988) 233-239.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
115300-03-3

KEGG   REACTION: R04510Help
Entry
R04510                      Reaction                               

Name
4-Carboxymethyl-4-methylbut-2-en-1,4-olide methylmutase
Definition
4-Methylmuconolactone <=> 3-Methylmuconolactone
Equation
Comment
multi-step reaction (lactone-lyase x2)
possibly intermediate (bislactone)
Reaction class
C04558_C04559
Enzyme
Pathway
Toluene degradation
Microbial metabolism in diverse environments
Other DBs
RHEA: 

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