KEGG   DRUG: D00235Help
Entry
D00235                      Drug                                   

Name
Atenolol (JP16/USP/INN);
Tenormin (TN)
Product
  Generic
ATENOLOL (Aidarex Pharmaceuticals LLC), ATENOLOL (American Health Packaging), ATENOLOL (Aphena Pharma Solutions - Tennessee), ATENOLOL (Aphena Pharma Solutions - Tennessee), ATENOLOL (Aphena Pharma Solutions - Tennessee), ATENOLOL (Aphena Pharma Solutions - Tennessee), ATENOLOL (Aurobindo Pharma Limited), ATENOLOL (Aurolife Pharma LLC), ATENOLOL (AvKARE), ATENOLOL (Blenheim Pharmacal), ATENOLOL (Blenheim Pharmacal), ATENOLOL (Bryant Ranch Prepack), ATENOLOL (Bryant Ranch Prepack), ATENOLOL (Bryant Ranch Prepack), ATENOLOL (Cadila Healthcare Limited), ATENOLOL (Cardinal Health), ATENOLOL (Clinical Solutions Wholesale), ATENOLOL (Contract Pharmacy Services-PA), ATENOLOL (Contract Pharmacy Services-PA), ATENOLOL (H.J. Harkins Company), ATENOLOL (Ingenus Pharmaceuticals), ATENOLOL (International Labs), ATENOLOL (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), ATENOLOL (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), ATENOLOL (Lake Erie Medical DBA Quality Care Products LLC), ATENOLOL (Lake Erie Medical DBA Quality Care Products LLC), ATENOLOL (Legacy Pharmaceutical Packaging), ATENOLOL (Major Pharmaceuticals), ATENOLOL (McKesson Contract Packaging), ATENOLOL (McKesson Contract Packaging), ATENOLOL (Med-Health Pharma), ATENOLOL (MedVantx), ATENOLOL (MedVantx), ATENOLOL (MedVantx), ATENOLOL (Mutual Pharmaceutical Company), ATENOLOL (Mylan Institutional), ATENOLOL (Mylan Pharmaceuticals), ATENOLOL (NCS HealthCare of KY), ATENOLOL (NCS HealthCare of KY), ATENOLOL (NCS HealthCare of KY), ATENOLOL (Northstar RxLLC), ATENOLOL (PD-Rx Pharmaceuticals), ATENOLOL (PD-Rx Pharmaceuticals), ATENOLOL (PD-Rx Pharmaceuticals), ATENOLOL (PD-Rx Pharmaceuticals), ATENOLOL (PD-Rx Pharmaceuticals), ATENOLOL (PD-Rx Pharmaceuticals), ATENOLOL (Pack Pharmaceuticals LLC), ATENOLOL (Physicians Total Care), ATENOLOL (Preferred Pharmaceuticals), ATENOLOL (Proficient Rx LP), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (REMEDYREPACK), ATENOLOL (Ranbaxy Pharmaceuticals), ATENOLOL (ReadyMeds), ATENOLOL (Rebel Distributors Corp), ATENOLOL (Rebel Distributors Corp), ATENOLOL (Rebel Distributors Corp.), ATENOLOL (Rebel Distributors Corp.), ATENOLOL (RedPharm Drug), ATENOLOL (RedPharm Drug), ATENOLOL (RedPharm Drug), ATENOLOL (RedPharm Drug), ATENOLOL (STAT RX USA LLC), ATENOLOL (Sandoz), ATENOLOL (Sandoz), ATENOLOL (St Marys Medical Park Pharmacy), ATENOLOL (St Marys Medical Park Pharmacy), ATENOLOL (State of Florida DOH Central Pharmacy), ATENOLOL (State of Florida DOH Central Pharmacy), ATENOLOL (State of Florida DOH Central Pharmacy), ATENOLOL (Teva Pharmaceuticals USA), ATENOLOL (Unit Dose Services), ATENOLOL (Unit Dose Services), ATENOLOL (Unit Dose Services), ATENOLOL (Zydus Pharmaceuticals (USA)), DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE (Preferred Pharmaceuticals)
Formula
C14H22N2O3
Exact mass
266.163
Mol weight
266.3361
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anti-adrenergic [beta-receptor]
Remark
Therapeutic category: 
ATC code: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Metabolism
Enzyme: CYP2D6 [HSA:1565]
Interaction
Drug interaction
Structure map
Antiarrhythmic drugs
Antimigraines
beta-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AB Beta blocking agents, selective
     C07AB03 Atenolol
      D00235  Atenolol (JP16/USP/INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Beta-adrenergic Blocking Agents
   Atenolol
    D00235  Atenolol (JP16/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   212  Antiarrhythmic agents
    2123  Beta blockers
     D00235  Atenolol (JP16/USP/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Atenolol
      D00235  Atenolol (JP16/USP/INN)
Cytochrome P450 interactions [BR:br08309]
 Substrates
  CYP2D6
   Atenolol
    D00235  Atenolol (JP16/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00235  Atenolol
BRITE hierarchy
Other DBs
CAS: 
29122-68-7
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   C8y C    24.1047  -18.4151
            2   C8x C    22.8989  -19.1258
            3   C8x C    24.0871  -17.0173
            4   O2a O    25.3278  -19.0908
            5   C8x C    21.6056  -18.4444
            6   C8x C    22.8639  -16.3241
            7   C1b C    26.5336  -18.3803
            8   C8y C    21.6641  -17.0406
            9   C1c C    27.7569  -19.0618
            10  C1b C    20.4524  -16.3357
            11  C1b C    28.9625  -18.3511
            12  O1a O    27.7743  -20.4598
            13  C5a C    19.2409  -17.0406
            14  N1b N    30.1741  -19.0327
            15  N1a N    18.0292  -16.3357
            16  O5a O    19.2409  -18.4444
            17  C1c C    31.3799  -18.3162
            18  C1a C    32.6030  -18.9977
            19  C1a C    31.3623  -16.9182
BOND        19
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 1
            7     5   8 1
            8     7   9 1
            9     8  10 1
            10    9  11 1
            11    9  12 1
            12   10  13 1
            13   11  14 1
            14   13  15 1
            15   13  16 2
            16   14  17 1
            17   17  18 1
            18   17  19 1
            19    6   8 2

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