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Entry
D00604                      Drug                                   

Name
Clonidine hydrochloride (JP16/USP);
Catapres (TN)
Product
  Generic
CLONIDINE (X-GEN Pharmaceuticals), CLONIDINE (STAT RX USA LLC), CLONIDINE HYDROCHLORIDE (A-S Medication Solutions LLC), CLONIDINE HYDROCHLORIDE (A-S Medication Solutions LLC), CLONIDINE HYDROCHLORIDE (Actavis Elizabeth LLC), CLONIDINE HYDROCHLORIDE (Aidarex Pharmaceuticals LLC), CLONIDINE HYDROCHLORIDE (Aidarex Pharmaceuticals LLC), CLONIDINE HYDROCHLORIDE (American Health Packaging), CLONIDINE HYDROCHLORIDE (American Regent), CLONIDINE HYDROCHLORIDE (Apotheca), CLONIDINE HYDROCHLORIDE (Blenheim Pharmacal), CLONIDINE HYDROCHLORIDE (BluePoint Laboratories), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Cardinal Health), CLONIDINE HYDROCHLORIDE (Cardinal Health), CLONIDINE HYDROCHLORIDE (Cardinal Health), CLONIDINE HYDROCHLORIDE (Cardinal Health), CLONIDINE HYDROCHLORIDE (Cardinal Health), CLONIDINE HYDROCHLORIDE (Carlsbad Technology), CLONIDINE HYDROCHLORIDE (Clinical Solutions Wholesale), CLONIDINE HYDROCHLORIDE (Contract Pharmacy Services-PA), CLONIDINE HYDROCHLORIDE (Contract Pharmacy Services-PA), CLONIDINE HYDROCHLORIDE (DAVA Pharmaceuticals), CLONIDINE HYDROCHLORIDE (DIRECT RX), CLONIDINE HYDROCHLORIDE (Dispensing Solutions), CLONIDINE HYDROCHLORIDE (Dispensing Solutions), CLONIDINE HYDROCHLORIDE (Fresenius Kabi USA), CLONIDINE HYDROCHLORIDE (General Injectables & Vaccines), CLONIDINE HYDROCHLORIDE (Global Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), CLONIDINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), CLONIDINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), CLONIDINE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), CLONIDINE HYDROCHLORIDE (Major Pharmaceuticals), CLONIDINE HYDROCHLORIDE (McKesson Contract Packaging), CLONIDINE HYDROCHLORIDE (McKesson Packaging Services a business unit of McKesson Corporation), CLONIDINE HYDROCHLORIDE (Med-Health Pharma), CLONIDINE HYDROCHLORIDE (MedVantx), CLONIDINE HYDROCHLORIDE (MedVantx), CLONIDINE HYDROCHLORIDE (Mutual Pharmaceutical Company), CLONIDINE HYDROCHLORIDE (Mylan Institutional), CLONIDINE HYDROCHLORIDE (Mylan Pharmaceuticals), CLONIDINE HYDROCHLORIDE (NCS HealthCare of KY), CLONIDINE HYDROCHLORIDE (NorthStar RxLLC), CLONIDINE HYDROCHLORIDE (Northwind Pharmaceuticals), CLONIDINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLONIDINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLONIDINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLONIDINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLONIDINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Par Pharmaceutical), CLONIDINE HYDROCHLORIDE (PharmaForce), CLONIDINE HYDROCHLORIDE (Physicians Total Care), CLONIDINE HYDROCHLORIDE (Preferred Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Preferred Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Preferred Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Preferred Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Qualitest Pharmaceuticals), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (Rebel Distributors Corp), CLONIDINE HYDROCHLORIDE (Richmond Pharmaceuticals), CLONIDINE HYDROCHLORIDE (STAT Rx USA LLC), CLONIDINE HYDROCHLORIDE (St Marys Medical Park Pharmacy), CLONIDINE HYDROCHLORIDE (St Marys Medical Park Pharmacy), CLONIDINE HYDROCHLORIDE (State of Florida DOH Central Pharmacy), CLONIDINE HYDROCHLORIDE (State of Florida DOH Central Pharmacy), CLONIDINE HYDROCHLORIDE (State of Florida DOH Central Pharmacy), CLONIDINE HYDROCHLORIDE (State of Florida DOH Central Pharmacy), CLONIDINE HYDROCHLORIDE (State of Florida DOH Central Pharmacy), CLONIDINE HYDROCHLORIDE (TYA Pharmaceuticals), CLONIDINE HYDROCHLORIDE (TYA Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Unichem Pharmaceuticals (USA)), CLONIDINE HYDROCHLORIDE (Unit Dose Services), CLONIDINE HYDROCHLORIDE (Unit Dose Services), CLONIDINE HYDROCHLORIDE (Unit Dose Services), CLONIDINE HYDROCHLORIDE (West-ward Pharmaceutical Corp)
Formula
C9H9Cl2N3. HCl
Exact mass
264.994
Mol weight
266.5548
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
alpha2-adrenergic receptor agonist [HSA:150 151 152] [KO:K04138 K04139 K04140]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
alpha-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C02 ANTIHYPERTENSIVES
   C02A ANTIADRENERGIC AGENTS, CENTRALLY ACTING
    C02AC Imidazoline receptor agonists
     C02AC01 Clonidine
      D00604  Clonidine hydrochloride (JP16/USP)
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02C ANTIMIGRAINE PREPARATIONS
    N02CX Other antimigraine preparations
     N02CX02 Clonidine
      D00604  Clonidine hydrochloride (JP16/USP)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
    S01EA Sympathomimetics in glaucoma therapy
     S01EA04 Clonidine
      D00604  Clonidine hydrochloride (JP16/USP)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Alpha-adrenergic Agonists
   Clonidine
    D00604  Clonidine hydrochloride (JP16/USP)
 Central Nervous System Agents
  Attention Deficit Hyperactivity Disorder Agents, Non- amphetamines
   Clonidine
    D00604  Clonidine hydrochloride (JP16/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D00604  Clonidine hydrochloride (JP16/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha2-adrenergic receptor
     Clonidine
      D00604  Clonidine hydrochloride (JP16/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00604  Clonidine hydrochloride
BRITE hierarchy
Other DBs
CAS: 
4205-91-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        15
            1   X   Cl   21.5859  -16.5853
            2   C8x C    12.8800  -15.9600
            3   C8x C    12.8800  -17.3600
            4   C8x C    14.0700  -18.0600
            5   C8y C    15.3300  -17.3600
            6   C8y C    15.3300  -15.9600
            7   C8y C    14.0700  -15.2600
            8   X   Cl   16.5200  -18.0600
            9   N1x N    17.7100  -17.3600
            10  C2y C    17.7100  -15.9600
            11  N2b N    16.5200  -15.2600
            12  C1x C    19.0400  -17.7800
            13  C1x C    19.8800  -16.6600
            14  N1x N    19.0400  -15.5400
            15  X   Cl   14.0700  -13.8600
BOND        15
            1     2   3 2
            2     3   4 1
            3     4   5 2
            4     5   6 1
            5     6   7 2
            6     2   7 1
            7     5   8 1
            8     9  10 1
            9    10  11 2
            10    6  11 1
            11    9  12 1
            12   12  13 1
            13   13  14 1
            14   10  14 1
            15    7  15 1

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