| Entry |
|
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| Name |
Terbutaline sulfate (JP18/USP);
Brethine (TN) |
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| Product |
|
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| Generic |
TERBUTALINE SULFATE (ANI Pharmaceuticals), TERBUTALINE SULFATE (Chartwell RX), TERBUTALINE SULFATE (Fresenius Kabi USA), TERBUTALINE SULFATE (Henry Schein), TERBUTALINE SULFATE (Hikma Pharmaceuticals USA), TERBUTALINE SULFATE (Hikma Pharmaceuticals USA), TERBUTALINE SULFATE (Lannett Company), TERBUTALINE SULFATE (Medical Purchasing Solutions), TERBUTALINE SULFATE (Medical Purchasing Solutions. LLC), TERBUTALINE SULFATE (Proficient Rx LP), TERBUTALINE SULFATE (TWi Pharmaceuticals), TERBUTALINE SULFATE (UBI Pharma) |
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| Formula |
(C12H19NO3)2. H2SO4
|
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| Exact mass |
548.2404
|
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| Mol weight |
548.6468
|
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| Structure |
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| Simcomp |
|
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| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
|
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| Remark |
| Therapeutic category: | 2252 |
| Product (DG01046): | D00688<JP/US> |
|
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| Efficacy |
Bronchodilator, beta2-Adrenergic receptor agonist |
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| Disease |
|
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| Comment |
Phenethylamine derivative
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03A ADRENERGICS, INHALANTS
R03AC Selective beta-2-adrenoreceptor agonists
R03AC03 Terbutaline
D00688 Terbutaline sulfate (JP18/USP) <JP/US>
R03C ADRENERGICS FOR SYSTEMIC USE
R03CC Selective beta-2-adrenoreceptor agonists
R03CC03 Terbutaline
D00688 Terbutaline sulfate (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Respiratory Tract/Pulmonary Agents
Bronchodilators, Sympathomimetic
Terbutaline
D00688 Terbutaline sulfate (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
22 Respiratory organ agents
225 Bronchodilators
2252 Isoprenalines
D00688 Terbutaline sulfate (JP18/USP)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01046 Terbutaline
D00688 Terbutaline sulfate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB2
D00688 Terbutaline sulfate (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00688 Terbutaline sulfate
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01046 Terbutaline
|
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| Other DBs |
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| KCF data |
ATOM 37
1 C8y C 21.3597 -18.5637
2 C1c C 22.5457 -19.2614
3 C8x C 21.3597 -17.1684
4 C8x C 20.1737 -19.2614
5 C1b C 23.8015 -18.5637
6 O1a O 22.5455 -20.6567
7 C8y C 20.1737 -16.4707
8 C8y C 18.9179 -18.5637
9 N1b N 24.9875 -19.2614
10 C8x C 18.9179 -17.1684
11 O1a O 20.1737 -15.0754
12 O1a O 17.7319 -19.2614
13 C1d C 26.1735 -18.5637
14 C1a C 27.4293 -19.2614
15 C1a C 27.4293 -17.8661
16 C1a C 26.1738 -17.1684
17 S4a S 32.1734 -17.8661
18 O1d O 30.7781 -17.8661
19 O1d O 33.5687 -17.8661
20 O1d O 32.1734 -16.4707
21 O1d O 32.1734 -19.2614
22 C8y C 21.3597 -18.5637
23 C1c C 22.5457 -19.2614
24 C1b C 23.8015 -18.5637
25 N1b N 24.9875 -19.2614
26 C1d C 26.1735 -18.5637
27 C1a C 27.4293 -19.2614
28 C1a C 27.4293 -17.8661
29 C1a C 26.1738 -17.1684
30 O1a O 22.5455 -20.6567
31 C8x C 21.3597 -17.1684
32 C8y C 20.1737 -16.4707
33 C8x C 18.9179 -17.1684
34 C8y C 18.9179 -18.5637
35 C8x C 20.1737 -19.2614
36 O1a O 17.7319 -19.2614
37 O1a O 20.1737 -15.0754
BOND 36
1 17 18 1
2 17 19 1
3 17 20 2
4 17 21 2
5 1 2 1
6 1 3 2
7 1 4 1
8 2 5 1
9 2 6 1
10 3 7 1
11 4 8 2
12 5 9 1
13 7 10 2
14 7 11 1
15 8 12 1
16 9 13 1
17 13 14 1
18 13 15 1
19 13 16 1
20 8 10 1
21 22 23 1
22 22 31 2
23 22 35 1
24 23 24 1
25 23 30 1
26 31 32 1
27 35 34 2
28 24 25 1
29 32 33 2
30 32 37 1
31 34 36 1
32 25 26 1
33 26 27 1
34 26 28 1
35 26 29 1
36 34 33 1
BRACKET 1 16.6600 -21.6300 16.6600 -14.2100
1 28.8400 -14.2100 28.8400 -21.6300
1 2
ORIGINAL 1 1 2 5 9 13 14 15 16 6 3 7 10 8 4 12 11
REPEAT 1 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
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