| Entry |
|
|---|
| Name |
Pramoxine hydrochloride (USP);
Pramocaine hydrochloride;
Tronothane (TN) |
|---|
| Formula |
C17H27NO3. HCl
|
|---|
| Exact mass |
329.1758
|
|---|
| Mol weight |
329.8621
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Remark |
| Product (mixture): | D11657<US> |
|
|---|
| Efficacy |
Analgesic (topical), Anesthetic (topical) |
|---|
| Target |
|
|---|
| Pathway |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AD Local anesthetics
C05AD07 Pramocaine
D00739 Pramoxine hydrochloride (USP)
D DERMATOLOGICALS
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04AB Anesthetics for topical use
D04AB07 Pramocaine
D00739 Pramoxine hydrochloride (USP)
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated ion channels
Sodium channels
SCN1A
D00739 Pramoxine hydrochloride (USP)
SCN2A
D00739 Pramoxine hydrochloride (USP)
SCN3A
D00739 Pramoxine hydrochloride (USP)
SCN4A
D00739 Pramoxine hydrochloride (USP)
SCN5A
D00739 Pramoxine hydrochloride (USP)
SCN8A
D00739 Pramoxine hydrochloride (USP)
SCN9A
D00739 Pramoxine hydrochloride (USP)
SCN10A
D00739 Pramoxine hydrochloride (USP)
SCN11A
D00739 Pramoxine hydrochloride (USP)
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 22
1 C8y C 23.0818 -19.3550
2 C8x C 23.0818 -20.7559
3 C8x C 21.8676 -18.6546
4 O2a O 24.2901 -18.6546
5 C8x C 21.8676 -21.4621
6 C8x C 20.6595 -19.3550
7 C1b C 25.5041 -19.3491
8 C8y C 20.6595 -20.7559
9 C1b C 26.7183 -18.6487
10 O2a O 19.4453 -21.4621
11 C1b C 27.9266 -19.3374
12 C1b C 18.2313 -20.7617
13 N1y N 29.1406 -18.6429
14 C1b C 17.0171 -21.4681
15 C1x C 30.3489 -19.3374
16 C1x C 29.1406 -17.2420
17 C1b C 15.8031 -20.7734
18 C1x C 31.5629 -18.6429
19 C1x C 30.3489 -16.5358
20 C1a C 14.5889 -21.4738
21 O2x O 31.5629 -17.2420
22 X Cl 29.9869 -22.5373
BOND 22
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 2
5 3 6 1
6 4 7 1
7 5 8 1
8 7 9 1
9 8 10 1
10 9 11 1
11 10 12 1
12 11 13 1
13 12 14 1
14 13 15 1
15 13 16 1
16 14 17 1
17 15 18 1
18 16 19 1
19 17 20 1
20 18 21 1
21 6 8 2
22 19 21 1
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