| Entry |
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| Name |
Cefotaxime sodium (JP18/USP);
Claforan (TN) |
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| Product |
|
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| Generic |
|
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| Formula |
C16H16N5O7S2. Na
|
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| Exact mass |
477.0389
|
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| Mol weight |
477.4473
|
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| Structure |
|
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| Simcomp |
|
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| Class |
|
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| Remark |
| Therapeutic category: | 6132 |
| Product (DG00570): | D00919<JP/US> |
|
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| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Target |
penicillin binding protein |
|---|
| Pathway |
|
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| Interaction |
|
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| Structure map |
| map07012 | Cephalosporins - parenteral agents |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DD Third-generation cephalosporins
J01DD01 Cefotaxime
D00919 Cefotaxime sodium (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Beta-lactam, Cephalosporins
Cefotaxime
D00919 Cefotaxime sodium (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6132 Cephem antibioitics
D00919 Cefotaxime sodium (JP18/USP)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00570 Cefotaxime
D00919 Cefotaxime sodium
DG01776 Third-generation cephalosporin
DG00570 Cefotaxime
D00919 Cefotaxime sodium
DG01804 Oxyimino beta-lactam
DG00570 Cefotaxime
D00919 Cefotaxime sodium
Drug classes [BR:br08332]
Antibacterial
DG01488 Cephem
D00919 Cefotaxime sodium
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
D00919 Cefotaxime sodium (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00919 Cefotaxime sodium
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00570 Cefotaxime
DG01776 Third-generation cephalosporin
DG00570 Cefotaxime
DG01804 Oxyimino beta-lactam
DG00570 Cefotaxime
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
DG00570 Cefotaxime
|
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| Other DBs |
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| KCF data |
ATOM 31
1 C1y C 32.5269 -17.4019
2 N1y N 32.5269 -18.8000
3 C2y C 33.7155 -19.4992
4 C2y C 34.9040 -18.8000
5 C1x C 34.9040 -17.4019
6 S2x S 33.7155 -16.7027
7 C1y C 31.1288 -17.4019
8 C5x C 31.1288 -18.8000
9 N1b N 29.8703 -16.7027
10 C5a C 28.6818 -17.4019
11 O5a O 28.6818 -18.8000
12 O5x O 29.8703 -19.4992
13 C2c C 27.4933 -16.7027
14 C1b C 36.1624 -19.4992
15 C8y C 26.2349 -17.4019
16 C8x C 25.1862 -16.5628
17 S2x S 23.9977 -17.3319
18 C8y C 24.4172 -18.7302
19 N5x N 25.8154 -18.7302
20 N2b N 27.4933 -15.3044
21 C6a C 33.7155 -20.8974
22 O6a O 34.9040 -21.5966 #-
23 O6a O 32.4571 -21.5966
24 N1a N 23.5782 -19.8487
25 O7a O 37.3660 -18.7774
26 C7a C 38.5855 -19.4548
27 C1a C 39.7687 -18.7450
28 O6a O 38.5387 -20.8548
29 O2a O 28.6918 -14.6188
30 C1a C 28.6918 -13.2205
31 Z Na 36.3022 -21.5966 #+
BOND 32
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 4 14 1
16 13 15 1
17 15 16 2
18 16 17 1
19 17 18 1
20 18 19 2
21 15 19 1
22 13 20 2
23 3 21 1
24 21 22 1
25 21 23 2
26 18 24 1
27 14 25 1
28 25 26 1
29 26 27 1
30 26 28 2
31 20 29 1
32 29 30 1
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