| Entry |
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| Name |
Calcium folinate (JP16);
Leucovorin calcium (USP);
Uzel (TN);
Wellcovorin (TN)
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| Product |
|
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| Generic |
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| Other |
|
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| Formula |
C20H21N7O7. Ca
|
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| Exact mass |
511.1128
|
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| Mol weight |
511.5014
|
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| Structure |
     |
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| Activity |
Anti-anemic [folate deficiency];
Antidote [to folic acid antagonists] [DS: H00020 H00046 H00047]
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| Remark |
Therapeutic category: ATC code: |
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| Comment |
Tetrahydrofolic acid [CPD: C00101] derivative
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| Interaction |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
39 Other agents affecting metabolism
392 Antidotes
3929 Others
D01211 Calcium folinate (JP16); Leucovorin calcium (USP)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
V VARIOUS
V03 ALL OTHER THERAPEUTIC PRODUCTS
V03A ALL OTHER THERAPEUTIC PRODUCTS
V03AF Detoxifying agents for antineoplastic treatment
V03AF03 Calcium folinate
D01211 Calcium folinate (JP16); Leucovorin calcium (USP)
USP drug classification [BR:br08302]
Antineoplastics
Antineoplastics, Other
Leucovorin
D01211 Calcium folinate (JP16); Leucovorin calcium (USP)
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| Other DBs |
CAS: 1492-18-8 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 35
1 C1c C 32.3723 -19.8825
2 C1b C 33.5708 -19.2034
3 C6a C 32.3609 -21.2859
4 C8y C 20.2354 -17.0151
5 N1y N 21.4257 -17.7153
6 C8y C 20.2354 -15.6148
7 C8y C 18.9752 -17.7153
8 C1y C 22.6860 -17.0151
9 N1x N 21.4257 -14.9147
10 N4x N 18.9752 -14.9147
11 N5x N 17.7849 -17.0151
12 O5x O 18.9752 -19.1156
13 C1x C 22.6860 -15.6148
14 C1b C 23.8762 -17.7153
15 C8y C 17.7849 -15.6148
16 N1a N 16.5947 -14.9147
17 N1b N 25.0946 -17.0250
18 C8y C 26.2762 -17.7203
19 C8x C 26.2647 -19.1156
20 C8x C 27.4716 -19.8257
21 C8y C 28.6900 -19.1356
22 C8x C 28.7015 -17.7403
23 C8x C 27.4947 -17.0301
24 C5a C 29.9007 -19.8480
25 N1b N 31.1304 -19.1519
26 O5a O 29.8891 -21.2160
27 O6a O 33.5582 -21.9903 #-
28 C1b C 34.7458 -19.8945
29 O6a O 31.1328 -21.9819
30 C6a C 35.9546 -19.2095
31 O6a O 37.1759 -19.9282 #-
32 O6a O 35.9657 -17.7855
33 C4a C 21.4085 -19.1100
34 O4a O 22.6207 -19.8299
35 Z Ca 35.5687 -21.5661 #2+
BOND 36
1 1 2 1
2 1 3 1 #Up
3 4 5 1
4 4 6 2
5 4 7 1
6 5 8 1
7 6 9 1
8 6 10 1
9 7 11 1
10 7 12 2
11 8 13 1
12 8 14 1
13 10 15 1
14 15 16 1
15 9 13 1
16 11 15 2
17 14 17 1
18 17 18 1
19 18 19 2
20 19 20 1
21 20 21 2
22 21 22 1
23 22 23 2
24 18 23 1
25 21 24 1
26 24 25 1
27 24 26 2
28 1 25 1
29 3 27 1
30 2 28 1
31 3 29 2
32 28 30 1
33 30 31 1
34 30 32 2
35 5 33 1
36 33 34 2
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