KEGG   DRUG: D01211Help
Entry
D01211                      Drug                                   

Name
Calcium folinate (JP16);
Leucovorin calcium (USP);
Uzel (TN);
Wellcovorin (TN)
Product
  Generic
Formula
C20H21N7O7. Ca
Exact mass
511.1128
Mol weight
511.5014
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anti-anemic [folate deficiency];
Antidote [to folic acid antagonists] [DS:H00020 H00046 H00047]
Remark
Therapeutic category: 
ATC code: 
Comment
Tetrahydrofolic acid [CPD:C00101] derivative
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 V VARIOUS
  V03 ALL OTHER THERAPEUTIC PRODUCTS
   V03A ALL OTHER THERAPEUTIC PRODUCTS
    V03AF Detoxifying agents for antineoplastic treatment
     V03AF03 Calcium folinate
      D01211  Calcium folinate (JP16); Leucovorin calcium (USP)
USP drug classification [BR:br08302]
 Antineoplastics
  Antineoplastics, Other
   Leucovorin
    D01211  Calcium folinate (JP16); Leucovorin calcium (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   392  Antidotes
    3929  Others
     D01211  Calcium folinate (JP16); Leucovorin calcium (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01211  Calcium folinate
BRITE hierarchy
Other DBs
CAS: 
1492-18-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        35
            1   C1c C    32.3723  -19.8825
            2   C1b C    33.5708  -19.2034
            3   C6a C    32.3609  -21.2859
            4   C8y C    20.2354  -17.0151
            5   N1y N    21.4257  -17.7153
            6   C8y C    20.2354  -15.6148
            7   C8y C    18.9752  -17.7153
            8   C1y C    22.6860  -17.0151
            9   N1x N    21.4257  -14.9147
            10  N4x N    18.9752  -14.9147
            11  N5x N    17.7849  -17.0151
            12  O5x O    18.9752  -19.1156
            13  C1x C    22.6860  -15.6148
            14  C1b C    23.8762  -17.7153
            15  C8y C    17.7849  -15.6148
            16  N1a N    16.5947  -14.9147
            17  N1b N    25.0946  -17.0250
            18  C8y C    26.2762  -17.7203
            19  C8x C    26.2647  -19.1156
            20  C8x C    27.4716  -19.8257
            21  C8y C    28.6900  -19.1356
            22  C8x C    28.7015  -17.7403
            23  C8x C    27.4947  -17.0301
            24  C5a C    29.9007  -19.8480
            25  N1b N    31.1304  -19.1519
            26  O5a O    29.8891  -21.2160
            27  O6a O    33.5582  -21.9903 #-
            28  C1b C    34.7458  -19.8945
            29  O6a O    31.1328  -21.9819
            30  C6a C    35.9546  -19.2095
            31  O6a O    37.1759  -19.9282 #-
            32  O6a O    35.9657  -17.7855
            33  C4a C    21.4085  -19.1100
            34  O4a O    22.6207  -19.8299
            35  Z   Ca   35.5687  -21.5661 #2+
BOND        36
            1     1   2 1
            2     1   3 1 #Up
            3     4   5 1
            4     4   6 2
            5     4   7 1
            6     5   8 1
            7     6   9 1
            8     6  10 1
            9     7  11 1
            10    7  12 2
            11    8  13 1
            12    8  14 1
            13   10  15 1
            14   15  16 1
            15    9  13 1
            16   11  15 2
            17   14  17 1
            18   17  18 1
            19   18  19 2
            20   19  20 1
            21   20  21 2
            22   21  22 1
            23   22  23 2
            24   18  23 1
            25   21  24 1
            26   24  25 1
            27   24  26 2
            28    1  25 1
            29    3  27 1
            30    2  28 1
            31    3  29 2
            32   28  30 1
            33   30  31 1
            34   30  32 2
            35    5  33 1
            36   33  34 2

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