| Entry |
|
|---|
| Name |
Penflutizide (JAN/INN) |
|---|
| Formula |
C13H18F3N3O4S2
|
|---|
| Exact mass |
401.0691
|
|---|
| Mol weight |
401.4249
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Efficacy |
Diuretic, Na+-Cl- symport inhibitor |
|---|
| Comment |
Thiazides
|
|---|
| Target |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG01749 Thiazide diuretic
D01241 Penflutizide
DG01690 Sulfonamide diuretic
DG01749 Thiazide diuretic
D01241 Penflutizide
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A3 (TSC)
D01241 Penflutizide (JAN/INN)
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 25
1 C8y C 26.3575 -18.4225
2 C8y C 26.3647 -19.8236
3 N1x N 25.1548 -20.5303
4 C1y C 23.9378 -19.8358
5 N1x N 23.9309 -18.4348
6 S2x S 25.1406 -17.7281
7 C8y C 28.7776 -18.4225
8 C8y C 28.7776 -19.8236
9 C8x C 27.5613 -20.5242
10 C8x C 27.5613 -17.7220
11 C1b C 22.7346 -20.5313
12 C1b C 21.5246 -19.8377
13 C1b C 20.3146 -20.5383
14 C1b C 19.1045 -19.8448
15 C1a C 17.8945 -20.5454
16 O3c O 23.9375 -17.0143
17 O3c O 26.3647 -17.0215
18 C1d C 29.9947 -20.5170
19 X F 31.2117 -21.2106
20 X F 29.9317 -21.9181
21 X F 31.2117 -19.8165
22 S4a S 29.9947 -17.7220
23 N1a N 31.2117 -17.0215
24 O3c O 30.6788 -18.9114
25 O3c O 29.2830 -16.4846
BOND 26
1 11 12 1
2 6 1 1
3 12 13 1
4 13 14 1
5 1 2 1
6 14 15 1
7 2 3 1
8 6 16 2
9 3 4 1
10 6 17 2
11 7 8 2
12 8 18 1
13 8 9 1
14 18 19 1
15 9 2 2
16 18 20 1
17 1 10 2
18 18 21 1
19 10 7 1
20 7 22 1
21 4 5 1
22 22 23 1
23 4 11 1
24 5 6 1
25 22 24 2
26 22 25 2
|
|---|
