| Entry |
|
|---|
| Name |
Tiaprofenic acid (JAN/INN);
Surgam (TN) |
|---|
| Formula |
C14H12O3S
|
|---|
| Exact mass |
260.0507
|
|---|
| Mol weight |
260.3083
|
|---|
| Structure |
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|---|
| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivatives
|
|---|
| Remark |
|
|---|
| Efficacy |
Analgesic, Anti-inflammatory, COX inhibitor |
|---|
| Comment |
Propionic acid derivative
|
|---|
| Target |
|
|---|
| Pathway |
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| Interaction |
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|---|
| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AE Propionic acid derivatives
M01AE11 Tiaprofenic acid
D01325 Tiaprofenic acid (JAN/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivatives
D01325 Tiaprofenic acid
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D01325 Tiaprofenic acid (JAN/INN)
PTGS2 (COX2)
D01325 Tiaprofenic acid (JAN/INN)
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| Other DBs |
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| KCF data |
ATOM 18
1 C8y C 26.6788 -17.9072
2 C1c C 27.8898 -17.2080
3 C6a C 29.1008 -17.9072
4 C1a C 27.8898 -15.8098
5 O6a O 29.1008 -19.3054
6 O6a O 30.3116 -17.2080
7 S2x S 25.5444 -17.0823
8 C8y C 24.4031 -17.9072
9 C8x C 24.8382 -19.2432
10 C8x C 26.2436 -19.2432
11 C8x C 19.5607 -17.9053
12 C8x C 19.5607 -19.3036
13 C8x C 20.7746 -20.0027
14 C8x C 21.9813 -19.3036
15 C8y C 21.9813 -17.9053
16 C8x C 20.7746 -17.2062
17 C5a C 23.1928 -17.2072
18 O5a O 23.1938 -15.8089
BOND 19
1 9 10 1
2 10 1 2
3 1 7 1
4 2 3 1
5 3 6 1
6 8 9 2
7 1 2 1
8 2 4 1
9 11 12 2
10 12 13 1
11 13 14 2
12 14 15 1
13 15 16 2
14 16 11 1
15 3 5 2
16 15 17 1
17 17 8 1
18 7 8 1
19 17 18 2
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