| Entry |
|
|---|
| Name |
Indenolol hydrochloride (JP18) |
|---|
| Formula |
C15H21NO2. HCl
|
|---|
| Exact mass |
283.1339
|
|---|
| Mol weight |
283.7937
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiarrhythmic, Antihypertensive, Vasodilator, beta-Adrenergic receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01323 Indenolol
D01958 Indenolol hydrochloride
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG01323 Indenolol
D01958 Indenolol hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB1
D01958 Indenolol hydrochloride (JP18)
ADRB2
D01958 Indenolol hydrochloride (JP18)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01958 Indenolol hydrochloride
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01323 Indenolol
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG01323 Indenolol
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 19
1 X Cl 26.2296 -16.2296
2 O2a O 15.6693 -16.8370
3 C1b C 16.8844 -16.1361
4 C1c C 18.0993 -16.8370
5 C1b C 19.3143 -16.1361
6 N1b N 20.5293 -16.8370
7 O1a O 18.0993 -18.2389
8 C1c C 21.7443 -16.1361
9 C1a C 22.9592 -16.8370
10 C1a C 21.7443 -14.7342
11 C8y C 15.6693 -18.2370
12 C8y C 14.4509 -18.9402
13 C8y C 14.4507 -20.3402
14 C8x C 15.6631 -21.0404
15 C8x C 16.8815 -20.3371
16 C8x C 16.8816 -18.9371
17 C2x C 13.1194 -18.5075
18 C2x C 12.2964 -19.6400
19 C1x C 13.1192 -20.7727
BOND 19
1 2 3 1
2 3 4 1
3 4 5 1
4 5 6 1
5 4 7 1 #Up
6 6 8 1
7 8 9 1
8 8 10 1
9 2 11 1
10 11 12 2
11 13 14 2
12 14 15 1
13 15 16 2
14 11 16 1
15 13 12 1
16 12 17 1
17 17 18 2
18 18 19 1
19 13 19 1
|
|---|
