| Entry |
|
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| Name |
Cocaine hydrochloride (JP18/USP);
Cocaine hydrochloride (TN) |
|---|
| Product |
|
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| Generic |
|
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| Formula |
C17H21NO4. HCl
|
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| Exact mass |
339.1237
|
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| Mol weight |
339.8139
|
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| Structure |
|
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| Simcomp |
|
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| Class |
|
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| Remark |
| Product (DG00808): | D02182<US> |
|
|---|
| Efficacy |
Anesthetic (topical), Narcotic |
|---|
| Target |
|
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| Pathway |
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| Interaction |
|
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| Structure map |
| map07234 | Neurotransmitter transporter inhibitors |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N01 ANESTHETICS
N01B ANESTHETICS, LOCAL
N01BC Esters of benzoic acid
N01BC01 Cocaine
D02182 Cocaine hydrochloride (JP18/USP) <US>
R RESPIRATORY SYSTEM
R02 THROAT PREPARATIONS
R02A THROAT PREPARATIONS
R02AD Anesthetics, local
R02AD03 Cocaine
D02182 Cocaine hydrochloride (JP18/USP) <US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01H LOCAL ANESTHETICS
S01HA Local anesthetics
S01HA01 Cocaine
D02182 Cocaine hydrochloride (JP18/USP) <US>
S02 OTOLOGICALS
S02D OTHER OTOLOGICALS
S02DA Analgesics and anesthetics
S02DA02 Cocaine
D02182 Cocaine hydrochloride (JP18/USP) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG02030 Anesthetics
DG01675 Local anesthetic
DG01674 Esterified local anesthetic
DG00808 Cocaine
D02182 Cocaine hydrochloride
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated ion channels
Sodium channels
SCN1A
D02182 Cocaine hydrochloride (JP18/USP) <US>
SCN2A
D02182 Cocaine hydrochloride (JP18/USP) <US>
SCN3A
D02182 Cocaine hydrochloride (JP18/USP) <US>
SCN4A
D02182 Cocaine hydrochloride (JP18/USP) <US>
SCN5A
D02182 Cocaine hydrochloride (JP18/USP) <US>
SCN8A
D02182 Cocaine hydrochloride (JP18/USP) <US>
SCN9A
D02182 Cocaine hydrochloride (JP18/USP) <US>
SCN10A
D02182 Cocaine hydrochloride (JP18/USP) <US>
SCN11A
D02182 Cocaine hydrochloride (JP18/USP) <US>
Potassium channels
KCNH2
D02182 Cocaine hydrochloride (JP18/USP) <US>
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D02182 Cocaine hydrochloride (JP18/USP) <US>
SLC6A3 (DAT1)
D02182 Cocaine hydrochloride (JP18/USP) <US>
SLC6A4 (HTT)
D02182 Cocaine hydrochloride (JP18/USP) <US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02182 Cocaine hydrochloride
Drug groups [BR:br08330]
Neuropsychiatric agent
DG02030 Anesthetics
DG01675 Local anesthetic
DG01674 Esterified local anesthetic
DG00808 Cocaine
|
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| Other DBs |
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| KCF data |
ATOM 23
1 X Cl 31.4535 -15.3767
2 C1x C 19.8800 -16.3800
3 C1x C 20.2300 -15.1900
4 C1y C 21.0700 -16.1000
5 C1y C 21.4200 -14.9100
6 N1y N 20.1600 -13.5800
7 C1x C 22.9600 -16.1000
8 C1y C 22.6800 -14.9100
9 C1y C 24.0100 -16.6600
10 O7a O 25.0600 -17.5000
11 C7a C 26.2500 -17.5000
12 C8y C 26.8800 -16.4500
13 O6a O 26.8800 -18.6900
14 C1a C 19.3900 -12.3900
15 C8x C 28.2800 -16.4500
16 C8x C 28.9800 -15.1900
17 C8x C 28.2800 -14.0000
18 C8x C 26.8800 -14.0000
19 C8x C 26.1800 -15.2600
20 C7a C 23.3100 -13.6500
21 O7a O 24.7100 -13.6500
22 O6a O 22.5400 -12.4600
23 C1a C 25.4100 -12.3900
BOND 24
1 2 3 1
2 2 4 1
3 3 5 1
4 4 6 1
5 4 7 1
6 5 8 1
7 7 9 1
8 9 10 1
9 10 11 1
10 11 12 1
11 11 13 2
12 5 6 1
13 8 9 1
14 6 14 1
15 12 15 2
16 15 16 1
17 16 17 2
18 17 18 1
19 18 19 2
20 12 19 1
21 8 20 1 #Up
22 20 21 1
23 20 22 2
24 21 23 1
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