| Entry |
|
|---|
| Name |
Hexamethonium bromide (JAN/INN);
Hexamethonium bromide (TN) |
|---|
| Formula |
C12H30N2. 2Br
|
|---|
| Exact mass |
360.0776
|
|---|
| Mol weight |
362.188
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
DG01742 Quaternary ammonium compound type muscle relaxant
|
|---|
| Efficacy |
Antihypertensive, Nicotinic acetylcholine receptor antagonist |
|---|
| Comment |
Quaternary ammonium compound
Ganglionic blocking agent
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07221 | Nicotinic cholinergic receptor antagonists |
|
|---|
| Brite |
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
D02204 Hexamethonium bromide
DG01742 Quaternary ammonium compound type muscle relaxant
D02204 Hexamethonium bromide
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRN (neuronal type)
D02204 Hexamethonium bromide (JAN/INN)
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 16
1 C1a C 18.2851 -15.8196
2 N1d N 19.5003 -16.5207 #+
3 C1b C 20.7156 -15.8196
4 C1b C 21.9309 -16.5207
5 C1b C 23.1461 -15.8196
6 C1b C 24.3614 -16.5207
7 C1b C 25.5767 -15.8196
8 C1b C 26.7919 -16.5207
9 N1d N 27.9605 -15.8196 #+
10 C1a C 29.1758 -16.5207
11 C1a C 18.2851 -17.1751
12 C1a C 20.7156 -17.2218
13 C1a C 29.3158 -14.9317
14 C1a C 26.7452 -15.1185
15 X Br 31.5470 -15.9134 #-
16 X Br 15.1202 -16.5201 #-
BOND 13
1 2 3 1
2 7 8 1
3 8 9 1
4 3 4 1
5 9 10 1
6 2 11 1
7 4 5 1
8 2 12 1
9 1 2 1
10 9 13 1
11 5 6 1
12 9 14 1
13 6 7 1
|
|---|
