| Entry |
|
|---|
| Name |
Timepidium bromide hydrate (JP18);
Sesden (TN) |
|---|
| Formula |
C17H22NOS2. Br. H2O
|
|---|
| Exact mass |
417.0432
|
|---|
| Mol weight |
418.412
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
Gastrointestinal agent
DG01975 Agents for peptic ulcer
|
|---|
| Remark |
| Therapeutic category: | 1249 |
| Product (DG00041): | D02535<JP> |
|
|---|
| Efficacy |
Antispasmodic, Muscarinic acetylcholine receptor antagonist |
|---|
| Comment |
Quaternary ammonium compound
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03AB Synthetic anticholinergics, quaternary ammonium compounds
A03AB19 Timepidium bromide
D02535 Timepidium bromide hydrate (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
12 Agents affecting peripheral nervous system
124 Antispasmodics
1249 Others
D02535 Timepidium bromide hydrate (JP18)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Timepidium bromide
D02535 Timepidium bromide hydrate (JP18)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00041 Timepidium bromide
D02535 Timepidium bromide hydrate
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG00041 Timepidium bromide
D02535 Timepidium bromide hydrate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D02535 Timepidium bromide hydrate (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02535 Timepidium bromide hydrate
Rx-to-OTC switch list in Japan [br08314.html]
D02535
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00041 Timepidium bromide
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG00041 Timepidium bromide
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 23
1 O0 O 29.0527 -21.0950
2 C1x C 19.2316 -23.0812
3 C1y C 20.4413 -23.7928
4 C1x C 21.6511 -23.0812
5 C2y C 21.6511 -21.7292
6 C1x C 20.4413 -21.0176
7 N2y N 19.2316 -21.7292 #+
8 O2a O 20.4413 -25.2160
9 C1a C 19.2316 -25.9276
10 C2c C 22.8608 -21.0176
11 C8y C 24.0705 -21.6580
12 C8y C 22.8608 -19.5944
13 C8x C 21.7222 -18.7405
14 C8x C 22.1492 -17.3884
15 C8x C 23.5724 -17.4596
16 S2x S 23.9993 -18.7405
17 C8x C 24.5686 -23.0100
18 C8x C 25.9206 -23.0100
19 C8x C 26.3476 -21.6580
20 S2x S 25.2090 -20.8753
21 C1a C 17.9962 -21.0226
22 C1a C 19.2316 -20.3060
23 X Br 19.3028 -18.0289 #-
BOND 23
1 4 5 1
2 5 10 2
3 5 6 1
4 10 11 1
5 6 7 1
6 10 12 1
7 7 2 1
8 12 13 2
9 13 14 1
10 14 15 2
11 15 16 1
12 16 12 1
13 2 3 1
14 3 8 1
15 3 4 1
16 11 17 2
17 17 18 1
18 18 19 2
19 19 20 1
20 20 11 1
21 8 9 1
22 7 21 1
23 7 22 1
|
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