| Entry |
|
|---|
| Name |
Celgosivir hydrochloride (USAN) |
|---|
| Formula |
C12H21NO5. HCl
|
|---|
| Exact mass |
295.1187
|
|---|
| Mol weight |
295.7598
|
|---|
| Structure |
|
|---|
| Class |
Antiviral
DG03198 Anti-HCV agent
DG01962 alpha-Glucosidase inhibitor, antiviral
|
|---|
| Efficacy |
Antiviral, Maturation inhibitor |
|---|
| Comment |
Maturation inhibitor
Indolizidine alkaloid derivative
Castanospermine [CPD: C02256] analog
|
|---|
| Target |
HCV envelope glycoprotein [KO: K22272] |
|---|
| Pathway |
|
|---|
| Structure map |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antiviral
DG03198 Anti-HCV agent
DG01962 alpha-Glucosidase inhibitor, antiviral
D03433 Celgosivir hydrochloride
Antimicrobials [BR:br08307]
Antivirals
Virus maturation inhibitor
HCV maturation inhibitor
D03433 Celgosivir hydrochloride (USAN)
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 19
1 C1y C 23.2370 -16.9578
2 C1y C 23.2370 -18.3126
3 C1x C 24.4102 -18.9900
4 N1y N 25.5835 -18.3126
5 C1y C 25.5835 -16.9578
6 C1y C 24.4102 -16.2804
7 O1a O 22.0637 -16.2804
8 O1a O 24.4102 -14.9258
9 O7a O 22.0637 -18.9900
10 C7a C 20.9068 -18.3219
11 C1b C 19.7578 -18.9853
12 O6a O 20.9067 -16.9581
13 C1b C 18.6051 -18.3195
14 C1a C 17.4540 -18.9840
15 C1x C 26.8720 -18.7313
16 C1x C 27.6684 -17.6352
17 C1y C 26.8720 -16.5392
18 O1a O 27.3110 -15.1880
19 X Cl 30.2818 -17.7030
BOND 19
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1 #Up
8 6 8 1 #Down
9 2 9 1 #Down
10 9 10 1
11 10 11 1
12 10 12 2
13 11 13 1
14 13 14 1
15 4 15 1
16 15 16 1
17 16 17 1
18 5 17 1
19 17 18 1 #Up
|
|---|
