| Entry |
|
|---|
| Name |
Liarozole hydrochloride (USAN) |
|---|
| Formula |
C17H13ClN4. HCl
|
|---|
| Exact mass |
344.0596
|
|---|
| Mol weight |
345.2259
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antineoplastic
DG01596 Aromatase inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Estrogen biosynthesis inhibitor |
|---|
| Comment |
Aromatase inhibitor
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG01596 Aromatase inhibitor
DG01293 Liarozole
D03784 Liarozole hydrochloride
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Cytochrome P450
CYP19A1 (ARO)
D03784 Liarozole hydrochloride (USAN)
Drug groups [BR:br08330]
Antineoplastic
DG01596 Aromatase inhibitor
DG01293 Liarozole
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 23
1 N4y N 31.4006 -17.6661
2 C1c C 31.4006 -19.0682
3 C8x C 32.5222 -16.8249
4 C8x C 32.1016 -15.4929
5 N5x N 30.6995 -15.4929
6 C8x C 30.2789 -16.8249
7 C8y C 30.2088 -19.7692
8 C8y C 32.6625 -19.7692
9 C8x C 29.0170 -19.0682
10 C8y C 27.7552 -19.7692
11 C8x C 27.7552 -21.1713
12 C8x C 29.0170 -21.8724
13 C8x C 30.2088 -21.1713
14 C8x C 32.6625 -21.1713
15 C8x C 33.8542 -21.8724
16 C8y C 35.0460 -21.1713
17 C8y C 35.0460 -19.7692
18 C8x C 33.8542 -19.0682
19 X Cl 26.5634 -19.0682
20 N5x N 36.3780 -21.5919
21 C8x C 37.2192 -20.4703
22 N4x N 36.3780 -19.3486
23 X Cl 41.5657 -19.7692
BOND 25
1 1 2 1
2 1 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 2 7 1
8 2 8 1
9 7 9 2
10 9 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 7 13 1
15 8 14 2
16 14 15 1
17 15 16 2
18 16 17 1
19 17 18 2
20 8 18 1
21 10 19 1
22 16 20 1
23 20 21 2
24 21 22 1
25 17 22 1
|
|---|
