Entry |
|
Name |
Enprofylline (USAN/INN) |
Formula |
C8H10N4O2
|
Exact mass |
194.0804
|
Mol weight |
194.1906
|
Structure |
|
Simcomp |
|
Class |
Respiratory system agent
DG01616 Xanthine derivative
DG01609 Xanthine-type bronchodilator
|
Efficacy |
Bronchodilator, Adenosine receptor antagonist |
Comment |
Xanthine derivative
|
Target |
|
Pathway |
hsa04080 | Neuroactive ligand-receptor interaction |
hsa04270 | Vascular smooth muscle contraction |
|
Interaction |
|
Brite |
Drug groups [BR:br08330]
Respiratory system agent
DG01616 Xanthine derivative
DG01609 Xanthine-type bronchodilator
D04006 Enprofylline
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adenosine
ADORA1
D04006 Enprofylline (USAN/INN)
ADORA2
D04006 Enprofylline (USAN/INN)
Enzymes
Hydrolases (EC3)
Phosphodiesterases
PDE
D04006 Enprofylline (USAN/INN)
|
Other DBs |
|
KCF data |
ATOM 14
1 N4x N 14.2100 -16.5200
2 C8y C 14.2100 -17.9200
3 N4y N 13.0200 -18.6200
4 C8y C 11.7600 -17.9200
5 C8y C 11.7600 -16.5200
6 C8y C 13.0200 -15.8200
7 O5x O 13.0200 -14.4200
8 O5x O 15.4000 -18.6200
9 N5x N 10.4300 -18.3400
10 C8x C 9.6600 -17.2200
11 N4x N 10.4300 -16.1000
12 C1b C 13.0200 -20.0200
13 C1b C 11.8300 -20.7200
14 C1a C 11.8300 -22.1200
BOND 15
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 1
7 6 7 2
8 2 8 2
9 4 9 1
10 9 10 2
11 10 11 1
12 5 11 1
13 3 12 1
14 12 13 1
15 13 14 1
|