| Entry |
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| Name |
laccase;
urishiol oxidase;
urushiol oxidase;
p-diphenol oxidase
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| Class |
Oxidoreductases;
Acting on diphenols and related substances as donors;
With oxygen as acceptor
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| Sysname |
benzenediol:oxygen oxidoreductase
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| Reaction(IUBMB) |
4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O [RN: R00083]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
A group of multi-copper proteins of low specificity acting on both o- and p-quinols, and often acting also on aminophenols and phenylenediamine. The semiquinone may react further either enzymically or non-enzymically.
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| Orthology |
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| Genes |
DHA: | | PIC: | | MGR: | | AFM: | | CNE: | | UMA: | | TTH: | |
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| Reference |
1 |
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| Authors |
Dawson, C.R. and Tarpley, W.B. |
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| Title |
The copper oxidases. |
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| Journal |
In: Sumner, J.B. and Myrback, K. (Eds.), The Enzymes, 1st ed., vol. 2, Academic Press, New York, 1951, p. 454-498. |
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| Reference |
2 |
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| Authors |
Keilin, D. and Mann, T. |
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| Title |
Laccase, a blue copper-protein oxidase from the latex of Rhus succedanea. |
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| Journal |
Nature (Lond.) 143 (1939) 23-24. |
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| Reference |
3 |
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| Authors |
Malmstrom, B.G., Andreasson, L.-E. and Reinhammar, B. |
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| Title |
Copper-containing oxidases and superoxide dismutase. |
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| Journal |
In: Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 12, Academic Press, New York, 1975, p. 507-579. |
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| Reference |
4 |
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| Authors |
Mayer, A.M. and Harel, E. |
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| Title |
Polyphenol oxidases in plants. |
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| Journal |
Phytochemistry 18 (1979) 193-215. |
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| Reference |
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| Authors |
NAKAMURA T. |
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| Title |
Purification and physico-chemical properties of laccase. |
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| Journal |
Biochim. Biophys. Acta. 30 (1958) 44-52. |
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| Organism |
Rhus vernicifera |
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| Reference |
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| Authors |
NAKAMURA T. |
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| Title |
Stoichiometric studies on the action of laccase. |
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| Journal |
Biochim. Biophys. Acta. 30 (1958) 538-42. |
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| Organism |
Rhus vernicifera |
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| Reference |
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| Authors |
PEISACH J, LEVINE WG. |
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| Title |
A COMPARISON OF THE ENZYMIC ACTIVITIES OF PIG CERULOPLASMIN AND RHUS VERNICIFERA LACCASE. |
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| Journal |
J. Biol. Chem. 240 (1965) 2284-9. |
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| Organism |
Sus scofa [GN: ssc], Rhus vernicifera |
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| Reference |
8 |
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| Authors |
Reinhammar, B. and Malmstrom, B.G. |
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| Title |
"Blue" copper-containing oxidases. |
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| Journal |
In: Spiro, T.G. (Ed.), Copper Proteins, Copper Proteins, New York, 1981, p. 109-149. |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: UM-BBD (Biocatalysis/Biodegradation Database): BRENDA, the Enzyme Database: CAS: 80498-15-3 |
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