KEGG   ENZYME: 1.17.1.4Help
Entry
EC 1.17.1.4                 Enzyme                                 
Name
xanthine dehydrogenase;
NAD+-xanthine dehydrogenase;
xanthine-NAD+ oxidoreductase;
xanthine/NAD+ oxidoreductase;
xanthine oxidoreductase
Class
Oxidoreductases;
Acting on CH or CH2 groups;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
xanthine:NAD+ oxidoreductase
Reaction(IUBMB)
xanthine + NAD+ + H2O = urate + NADH + H+ [RN:R02103]
Reaction(KEGG)
R02103;
(other) R01768
Show
Substrate
xanthine [CPD:C00385];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
urate [CPD:C00366];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Acts on a variety of purines and aldehydes, including hypoxanthine. The mammalian enzyme can also convert all-trans retinol to all-trans-retinoate, while the substrate is bound to a retinoid-binding protein [14]. The enzyme from eukaryotes contains [2Fe-2S], FAD and a molybdenum centre. The mammalian enzyme predominantly exists as the NAD-dependent dehydrogenase (EC 1.17.1.4). During purification the enzyme is largely converted to an O2-dependent form, xanthine oxidase (EC 1.17.3.2). The conversion can be triggered by several mechanisms, including the oxidation of cysteine thiols to form disulfide bonds [2,6,8,15] [which can be catalysed by EC 1.8.4.7, enzyme-thiol transhydrogenase (glutathione-disulfide) in the presence of glutathione disulfide] or limited proteolysis, which results in irreversible conversion. The conversion can also occur in vivo [2,7,15].
Pathway
Purine metabolism
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K00087  
xanthine dehydrogenase molybdenum-binding subunit
K00106  
xanthine dehydrogenase/oxidase
K11177  
xanthine dehydrogenase YagR molybdenum-binding subunit
K11178  
xanthine dehydrogenase YagS FAD-binding subunit
K13479  
xanthine dehydrogenase FAD-binding subunit
K13481  
xanthine dehydrogenase small subunit
K13482  
xanthine dehydrogenase large subunit
Genes
HSA: 
7498(XDH)
PTR: 
470347(XDH)
PPS: 
GGO: 
PON: 
MCC: 
708046(XDH)
MMU: 
22436(Xdh)
RNO: 
497811(Xdh)
CFA: 
483028(XDH)
AML: 
FCA: 
493692(XDH)
BTA: 
280960(XDH)
SSC: 
100515259(XDH)
ECB: 
100054601
MDO: 
100031481(XDH)
SHR: 
100933358(XDH)
OAA: 
100078370
GGA: 
396025(XDH)
MGP: 
100544067
TGU: 
100222890(XDH)
ACS: 
100566790
XTR: 
100497499
DRE: 
560486(xdh)
TRU: 
101073141
OLA: 
101162508
BFO: 
BRAFLDRAFT_216227
CIN: 
100181350
SPU: 
576712(XDH)
DME: 
Dmel_CG7642(ry)
DPO: 
Dpse_GA20500(Dpse_ry)
DAN: 
Dana_GF16930(Dana_Xdh)
DER: 
Dere_GG19379(Dere_Xdh)
DPE: 
Dper_GL11934 Dper_GL11936 Dper_GL24383(Dper_ry)
DSE: 
Dsec_GM24078
DSI: 
Dsim_GD18875(Dsim_ry)
DWI: 
Dwil_GK11683 Dwil_GK11684 Dwil_GK12225(Dwil_ry)
DYA: 
Dyak_GE26236(Dyak_ry) Dyak_GE26368
DGR: 
Dgri_GH18370
DMO: 
Dmoj_GI22594 Dmoj_GI23360(Dmoj_Xdh)
DVI: 
Dvir_GJ10353(Dvir_ry)
AGA: 
AgaP_AGAP006226 AgaP_AGAP007918
AAG: 
AaeL_AAEL002683 AaeL_AAEL010384
CQU: 
CpipJ_CPIJ004365
AME: 
724718
NVI: 
100122636(NV12536) 100123244(NV11546) 100123252(NV11547)
TCA: 
655982 656621
API: 
100169249
PHU: 
Phum_PHUM299090
CEL: 
CELE_F55B11.1(F55B11.1)
CBR: 
CBG21624
NVE: 
NEMVE_v1g192610
TAD: 
TRIADDRAFT_26553 TRIADDRAFT_27111
AQU: 
100631741 100640399
ATH: 
AT4G34890(XDH1) AT4G34900(XDH2)
ALY: 
ARALYDRAFT_491165 ARALYDRAFT_912004
GMX: 
100800309
MTR: 
MTR_2g098030
CSV: 
101211977
RCU: 
RCOM_1577610
POP: 
POPTR_804467(XDH1)
VVI: 
100248547
OSA: 
4333171
DOSA: 
Os03t0429800-01(Os03g0429800)
BDI: 
100827961
SMO: 
SELMODRAFT_172098(XDH-2) SELMODRAFT_443347 SELMODRAFT_83922(XDH-1)
PPP: 
PHYPADRAFT_162514 PHYPADRAFT_172226
CRE: 
CHLREDRAFT_117669(XDH1)
VCN: 
VOLCADRAFT_63971
PPA: 
PAS_chr2-2_0112
NCR: 
NCU03350
SMP: 
SMAC_04084
PAN: 
PODANSg6463
TTT: 
THITE_2123410
MTM: 
MYCTH_2311689
MGR: 
MGG_12738
FGR: 
FG01561.1
NHE: 
NECHADRAFT_74201 NECHADRAFT_93123
VAL: 
VDBG_05801
SSL: 
SS1G_08428 SS1G_14350
BFU: 
BC1G_03118
ANI: 
AN5613.2 AN9178.2
NFI: 
NFIA_094210 NFIA_105140
AFM: 
AFUA_4G11220
AOR: 
AOR_1_1958154(AO090003001099)
ANG: 
ANI_1_902184(An04g05440)
AFV: 
AFLA_027200
ACT: 
ACLA_050310
PCS: 
Pc22g06330
CIM: 
CIMG_01495
CPW: 
CPC735_049500
PBL: 
PAAG_02640 PAAG_03629
URE: 
UREG_05104
ABE: 
ARB_02280
TVE: 
TRV_04973
AJE: 
HCAG_01659 HCAG_06867
PNO: 
SNOG_04191 SNOG_07509
PTE: 
PTT_04424 PTT_07497
ZTR: 
MYCGRDRAFT_53902
UMA: 
UM03264.1
MBR: 
MONBRDRAFT_16701
NGR: 
NAEGRDRAFT_62716
DDI: 
DDB_G0291047(xdh)
DPP: 
DICPUDRAFT_96745
TVA: 
TVAG_416300 TVAG_433470
PTI: 
PHATRDRAFT_15968
TPS: 
THAPSDRAFT_270071
PIF: 
PITG_02284
ECO: 
b0284(paoC) b0285(paoB) b2866(xdhA) b2867(xdhB)
ECJ: 
Y75_p0276(yagR) Y75_p0277(yagS) Y75_p2799(xdhA) Y75_p2800(xdhB)
ECD: 
ECDH10B_0272(yagR) ECDH10B_0273(yagS) ECDH10B_3041(xdhA) ECDH10B_3042(xdhB)
EBW: 
BWG_2592(xdhA) BWG_2593(xdhB)
ECOK: 
ECMDS42_2366(xdhA) ECMDS42_2367(xdhB)
ECE: 
Z0350(yagR) Z0351(yagS) Z4205 Z4206(ygeT)
ECS: 
ECs0314 ECs0315 ECs3739 ECs3740
ECF: 
ECH74115_0330 ECH74115_0331 ECH74115_4156(xdhA) ECH74115_4157(xdhB)
ETW: 
ECSP_0321(yagR) ECSP_0322(yagS) ECSP_3836(xdhA) ECSP_3837(xdhB)
ELX: 
CDCO157_0309 CDCO157_0310 CDCO157_3492 CDCO157_3493
EOJ: 
ECO26_0319(yagR) ECO26_0320(yagS) ECO26_3955(xdhA) ECO26_3956(xdhB)
EOI: 
ECO111_3604(xdhA) ECO111_3605(xdhB)
EOH: 
ECO103_0261(yagR) ECO103_0262(yagS) ECO103_3441(xdhA) ECO103_3442(xdhB)
ECG: 
E2348C_3118(xdhA) E2348C_3119(xdhB)
EOK: 
G2583_0376(yagR) G2583_0377(yagS) G2583_3520(xdhA) G2583_3521(xdhB)
ELR: 
ECO55CA74_01770 ECO55CA74_01775 ECO55CA74_16775 ECO55CA74_16780
ECC: 
c3444 c3445(ygeT)
ECP: 
ECP_2860 ECP_2861
ECI: 
UTI89_C3251 UTI89_C3252(ygeT)
ECV: 
APECO1_3658(ygeT) APECO1_3659
ECX: 
EcHS_A3026(xdhA) EcHS_A3027(xdhB)
ECW: 
EcE24377A_0295 EcE24377A_0296 EcE24377A_3191(xdhA) EcE24377A_3192(xdhB)
ECM: 
EcSMS35_2999(xdhA) EcSMS35_3000(xdhB)
ECY: 
ECSE_0302 ECSE_0303 ECSE_3130 ECSE_3131
ECR: 
ECIAI1_0285(yagR) ECIAI1_0286(yagS) ECIAI1_2986(xdhA) ECIAI1_2987(xdhB)
ECQ: 
ECED1_3326(xdhA) ECED1_3327(xdhB)
ECK: 
EC55989_0289(yagR) EC55989_0290(yagS) EC55989_3153(xdhA) EC55989_3154(xdhB)
ECT: 
ECIAI39_3281(xdhA) ECIAI39_3282(xdhB)
EOC: 
CE10_3305(xdhA) CE10_3306(xdhB)
EUM: 
ECUMN_0315(yagR) ECUMN_0316(yagS) ECUMN_3209(xdhA) ECUMN_3210(xdhB)
ECZ: 
ECS88_3145(xdhA) ECS88_3146(xdhB)
ELO: 
EC042_0314 EC042_0315 EC042_3077(xdhA) EC042_3078(xdhB)
ELN: 
NRG857_14065 NRG857_14070
ELH: 
ETEC_0341 ETEC_0342 ETEC_3060 ETEC_3061
ESE: 
ECSF_2662 ECSF_2663
ESO: 
O3O_05220 O3O_05225 O3O_20510 O3O_20515
ESM: 
O3M_05175 O3M_05180 O3M_20055 O3M_20060
ESL: 
O3K_05130 O3K_05135 O3K_20065 O3K_20070
ECL: 
EcolC_0841 EcolC_0842 EcolC_3334 EcolC_3335
EBR: 
ECB_00243(yagR) ECB_00244(yagS) ECB_02699(xdhA) ECB_02700(xdhB)
EBD: 
ECBD_0870 ECBD_0871 ECBD_3372 ECBD_3373
EKO: 
EKO11_0864 EKO11_0865 EKO11_3560 EKO11_3561
EKF: 
KO11_08430(xdhB) KO11_08435(xdhA) KO11_22180(yagS) KO11_22185(yagR)
EAB: 
ECABU_c31470(xdhA) ECABU_c31480(xdhB)
EDH: 
EcDH1_0825 EcDH1_0826 EcDH1_3319 EcDH1_3320
EDJ: 
ECDH1ME8569_0273(yagR) ECDH1ME8569_0274(yagS) ECDH1ME8569_2769(xdhA) ECDH1ME8569_2770(xdhB)
EIH: 
ECOK1_3252(xdhA) ECOK1_3253(xdhB)
ENA: 
ECNA114_2907 ECNA114_2908(ygeT)
ELU: 
UM146_02185 UM146_02190
EUN: 
UMNK88_332 UMNK88_333 UMNK88_3558 UMNK88_3559
ELW: 
ECW_m0361(yagR) ECW_m0362(yagS) ECW_m3119(xdhA) ECW_m3120(xdhB)
ELL: 
WFL_01755(yagR) WFL_01760(yagS) WFL_15230(xdhA) WFL_15235(xdhB)
ELC: 
i14_3163 i14_3164(ygeT)
ELD: 
i02_3163 i02_3164(ygeT)
ELP: 
P12B_c2964(xdhA) P12B_c2965(xdhB)
EBL: 
ECD_00243(yagR) ECD_00244(yagS) ECD_02699(xdhA) ECD_02700(xdhB)
EBE: 
B21_00246(yagR) B21_00247(yagS) B21_02661(xdhA) B21_02662(xdhB)
ELF: 
LF82_2443(xdhA) LF82_2444(xdhB)
ECOA: 
APECO78_04950 APECO78_04955 APECO78_18045 APECO78_18050
EFE: 
EFER_2820(yagS) EFER_2821(yagR)
SFL: 
SF2868 SF2869(ygeT)
SFX: 
S3068 S3069(ygeT)
SFV: 
SFV_2931 SFV_2932(ygeT)
SFE: 
SFxv_3142(xdhB)
SSN: 
SSON_3017 SSON_3018(ygeT)
SSJ: 
SSON53_17630 SSON53_17635
SBO: 
SBO_3118(ygeT) SBO_3119
EBI: 
EbC_22720 EbC_22730
ESC: 
Entcl_2780 Entcl_2781
ESA: 
ESA_04145 ESA_04146
CSK: 
ES15_0115(yagS) ES15_0116(yagR)
CSZ: 
CSSP291_19185 CSSP291_19190
CTU: 
CTU_40910(yagR) CTU_40920(yagS)
CRO: 
ROD_03851 ROD_03861
SPE: 
Spro_2300 Spro_2301
SRR: 
SerAS9_2255 SerAS9_2256
SRS: 
SerAS12_2255 SerAS12_2256
SRA: 
SerAS13_2256 SerAS13_2257
SMAF: 
D781_2349 D781_2350
EIC: 
NT01EI_0685 NT01EI_0686
ETR: 
ETAE_0588(xdhB) ETAE_0589(xdhA)
ETD: 
ETAF_0536 ETAF_0537
ETC: 
ETAC_02850 ETAC_02855
PAM: 
PANA_1963(xdh) PANA_4205(yagS) PANA_4206(yagR)
PLF: 
PANA5342_2215(xdhA) PANA5342_2216(xdhB) PANA5342_p10023(yagS) PANA5342_p10024(yagR)
PAJ: 
PAJ_1295(xdh) PAJ_p0081(yagR) PAJ_p0082(yagS)
PAQ: 
PAGR_g2141 PAGR_g2142 PAGR_p018 PAGR_p019
PVA: 
Pvag_1370(xdhB) Pvag_1371(xdhA) Pvag_pPag30476(aomL) Pvag_pPag30477(aomM)
PAO: 
Pat9b_1958 Pat9b_1959
RAH: 
Rahaq_2216 Rahaq_2217
RAQ: 
Rahaq2_1048 Rahaq2_1049 Rahaq2_2312 Rahaq2_2313
RAA: 
Q7S_11210 Q7S_11215
MMK: 
MU9_1085 MU9_1086
EBF: 
D782_2161 D782_2162
XCC: 
XCC1091 XCC1092 XCC2727(yagR) XCC2728(yagS) XCC3709(yagR)
XCB: 
XC_1386 XC_1387 XC_3157 XC_3158 XC_3780
XCA: 
xccb100_1435 xccb100_1436 xccb100_3253 xccb100_3254 xccb100_3896
XCV: 
XCV1214 XCV1215 XCV3044 XCV3045
XCP: 
XCR_0597 XCR_1306 XCR_1307 XCR_3091 XCR_3092
XAC: 
XAC1187 XAC1188 XAC2893(yagR) XAC2894(yagS)
XAX: 
XACM_1157 XACM_1158 XACM_2832 XACM_2833
XAO: 
XAC29_05960 XAC29_05965 XAC29_14745 XAC29_14750
XOR: 
XOC_1519 XOC_1520
XCI: 
XCAW_01288(coxL) XCAW_01289(coxM) XCAW_03177(coxL) XCAW_03178(coxM)
SML: 
Smlt2503(yagR) Smlt2504(yagS)
SMT: 
Smal_1991 Smal_1992
BUJ: 
BurJV3_2040 BurJV3_2041
SMZ: 
SMD_2183(yagR) SMD_2184(yagS)
PSD: 
DSC_08835 DSC_08840 DSC_13830 DSC_13835
VEJ: 
VEJY3_17081 VEJY3_17086
VFU: 
vfu_B00188 vfu_B00189
PPR: 
PBPRA2243 PBPRA2244
PAE: 
PA1523(xdhB) PA1524(xdhA) PA1932 PA1933
PAU: 
PA14_39520 PA14_39530 PA14_44710(xdhA) PA14_44740(xdhB)
PAP: 
PSPA7_3354 PSPA7_3355 PSPA7_3809(xdhA) PSPA7_3810(xdhB)
PAG: 
PLES_33901 PLES_33911 PLES_38041(xdhA) PLES_38051(xdhB)
PAF: 
PAM18_3106 PAM18_3107 PAM18_3524(xdhA) PAM18_3525(xdhB)
PNC: 
NCGM2_2409(xdhB) NCGM2_2410(xdhA) NCGM2_2853 NCGM2_2854
PDK: 
PADK2_18105
PSG: 
G655_15440 G655_15445 G655_17600 G655_17605
PPU: 
PP_3309 PP_3310 PP_4278(xdhA) PP_4279(xdhB)
PPF: 
Pput_1589 Pput_1590 Pput_2433 Pput_2434
PPG: 
PputGB1_3842 PputGB1_3843
PPW: 
PputW619_2855 PputW619_2856 PputW619_3604 PputW619_3605
PPT: 
PPS_3682 PPS_3683
PPB: 
PPUBIRD1_1576(xdhB) PPUBIRD1_1577(xdhA) PPUBIRD1_2455 PPUBIRD1_2456
PPI: 
YSA_08281 YSA_08283 YSA_11048 YSA_11050
PPX: 
T1E_0308(yagS) T1E_0309(yagR) T1E_0743(hxA) T1E_0744(xdh) T1E_5456 T1E_5457
PPUH: 
B479_18255 B479_18260
PPUU: 
PputUW4_03599(xdhA) PputUW4_03600(xdhB)
PST: 
PSPTO_2655 PSPTO_2862 PSPTO_2863 PSPTO_3660 PSPTO_3661 PSPTO_4650 PSPTO_4651
PSB: 
Psyr_1814 Psyr_1815 Psyr_2389 Psyr_4283 Psyr_4284
PSP: 
PSPPH_1774 PSPPH_1775(xdhA) PSPPH_2547 PSPPH_2548 PSPPH_4342
PFL: 
PFL_1888(xdhB) PFL_1889(xdhA)
PFO: 
Pfl01_1796 Pfl01_1797 Pfl01_2107 Pfl01_2108
PFS: 
PFLU4592 PFLU4593 PFLU5348 PFLU5349
PFE: 
PSF113_4030 PSF113_4031 PSF113_5084(yagR) PSF113_5085(yagS)
PFC: 
PflA506_3892(xdhA) PflA506_3893(xdhB) PflA506_4643 PflA506_4644
PPZ: 
H045_13760 H045_13765 H045_17195 H045_17200
PEN: 
PSEEN1764 PSEEN1765
PMY: 
Pmen_2345 Pmen_2346 Pmen_2751 Pmen_2752
PMK: 
MDS_1926 MDS_1927
PSA: 
PST_0925 PST_0926 PST_3081(xdhA) PST_3082(xdhB)
PSZ: 
PSTAB_0819 PSTAB_0820 PSTAB_3128(xdhA) PSTAB_3129(xdhB)
PSR: 
PSTAA_0870 PSTAA_0871 PSTAA_3244(xdhA) PSTAA_3245(xdhB)
PSC: 
A458_05240 A458_05245 A458_17120 A458_17125 A458_17845 A458_17850
PSJ: 
PSJM300_14265 PSJM300_14270 PSJM300_16660 PSJM300_16665
PSH: 
Psest_1210 Psest_1211 Psest_3444 Psest_3445
PBA: 
PSEBR_a1702 PSEBR_a1703 PSEBR_a4899 PSEBR_a4900
PFV: 
Psefu_3530 Psefu_3531
PDR: 
H681_00920 H681_15330 H681_15335
CJA: 
CJA_0546(xdhA) CJA_0547(xdhB)
AVN: 
Avin_22280(xdhB) Avin_22290(xdhA)
AVL: 
AvCA_22280(xdhB) AvCA_22290(xdhA)
AVD: 
AvCA6_22280(xdhB) AvCA6_22290(xdhA)
PCR: 
Pcryo_1140 Pcryo_1141 Pcryo_1807 Pcryo_1808
PRW: 
PsycPRwf_1008 PsycPRwf_1009
ACI: 
ACIAD2467(xdhB) ACIAD2468(xdhA)
ACD: 
AOLE_05230 AOLE_05235
ACB: 
A1S_2364 A1S_2365
ABM: 
ABSDF1158(xdhA) ABSDF1159(xdhB)
ABY: 
ABAYE1114(xdhA) ABAYE1115(xdhB)
ABC: 
ACICU_02560 ACICU_02561
ABN: 
AB57_2793(xdhB) AB57_2794(xdhA)
ABB: 
ABBFA_001078(xdhA) ABBFA_001079(xdhB)
ABX: 
ABK1_2676 ABK1_2677
ABZ: 
ABZJ_02753 ABZJ_02754
ABR: 
ABTJ_01153 ABTJ_01154
ABD: 
ABTW07_2810(xdhB) ABTW07_2811(xdhA)
ABH: 
M3Q_2826 M3Q_2827
ABAD: 
ABD1_23590(xdhB) ABD1_23600(xdhA)
ACC: 
BDGL_001851(xdhB) BDGL_001852(xdhA)
CPS: 
CPS_4864 CPS_4865
PAT: 
Patl_2424 Patl_2425
AMC: 
MADE_1007935 MADE_1007940 MADE_1014120 MADE_1014125
AMAC: 
MASE_07165 MASE_07170 MASE_13550 MASE_13555
AMB: 
AMBAS45_07690 AMBAS45_07695 AMBAS45_14070 AMBAS45_14075
AMG: 
AMEC673_07215 AMEC673_07220 AMEC673_13850 AMEC673_13855
AMK: 
AMBLS11_07165 AMBLS11_07170 AMBLS11_13485 AMBLS11_13490
AMAA: 
amad1_08015 amad1_08020 amad1_14460 amad1_14465
ALT: 
ambt_05135 ambt_05140 ambt_10835 ambt_10840
GAG: 
Glaag_1942 Glaag_1944
GPS: 
C427_3034 C427_3035
TTU: 
TERTU_2066(xdhB) TERTU_2067(xdhA)
MAH: 
MEALZ_1436(xdhB) MEALZ_1437(xdhA)
TNI: 
TVNIR_1715(xdhA_[H]) TVNIR_1716(pucE_[H])
HNA: 
Hneap_0859 Hneap_0860
HCH: 
HCH_01098(xdhB) HCH_01099(xdhA)
CSA: 
Csal_0528 Csal_0529 Csal_1788 Csal_1789
HEL: 
HELO_2465(xdhB) HELO_2466(xdhA)
MMW: 
Mmwyl1_2698 Mmwyl1_2699
MME: 
Marme_2873 Marme_2874
MPC: 
Mar181_1394 Mar181_1395
TOL: 
TOL_3284 TOL_3285
AHA: 
AHA_2177 AHA_2178
AVR: 
B565_1863 B565_1864
OCE: 
GU3_15940 GU3_15945
AFE: 
Lferr_0951 Lferr_0952
AFR: 
AFE_0808 AFE_0809
PSE: 
NH8B_0243(xdhB) NH8B_0244(xdhA)
RSO: 
RSc2095(xdhA) RSc2096(xdhB)
RSC: 
RCFBP_11293(xdhB) RCFBP_11294(xdhA)
RSL: 
RPSI07_1333(xdhB) RPSI07_1334(xdhA)
RSN: 
RSPO_c01337(xdhB) RSPO_c01338(xdhA)
RPI: 
Rpic_2246 Rpic_2247 Rpic_3374 Rpic_3375
RPF: 
Rpic12D_1922 Rpic12D_1923 Rpic12D_3027 Rpic12D_3028
REU: 
Reut_A2425 Reut_A2426 Reut_A3076 Reut_B4506 Reut_B4507
REH: 
H16_A1016(xdhB1) H16_A1017(xdhA1) H16_A3371(coxL5) H16_B1897(xdhA2) H16_B1898(xdhB2)
RME: 
Rmet_0892(xdhB) Rmet_0893(xdhA)
CTI: 
RALTA_A1000(xdhB2) RALTA_A1001(xdhA2) RALTA_A2830(xdhA1) RALTA_B0867(yagS2) RALTA_B0868(yagR2) RALTA_B0900(yagR1) RALTA_B0901(yagS1)
CNC: 
CNE_1c09590(xdhB) CNE_1c09600(xdhA) CNE_2c10370(yagR) CNE_2c10380(yagS)
BMA: 
BMA2041 BMA2042
BMV: 
BMASAVP1_A0871 BMASAVP1_A0872
BML: 
BMA10229_A2705 BMA10229_A2706
BMN: 
BMA10247_1904 BMA10247_1905
BPS: 
BPSL2727(xdhB) BPSL2728(xdhA)
BPM: 
BURPS1710b_3213(xdhB) BURPS1710b_3215(xdhA)
BPL: 
BURPS1106A_3198(xdhB) BURPS1106A_3199
BPD: 
BURPS668_3159(xdhB) BURPS668_3160(xdhA)
BPR: 
GBP346_A3339(xdhB) GBP346_A3340(xdhA)
BPZ: 
BP1026B_I0587(xdhA) BP1026B_I0588(xdhB)
BPQ: 
BPC006_I3240 BPC006_I3241
BTE: 
BTH_I1408 BTH_I1409
BVI: 
Bcep1808_0769 Bcep1808_0770 Bcep1808_3040 Bcep1808_3041
BUR: 
Bcep18194_A3924 Bcep18194_A3925
BCN: 
Bcen_0348 Bcen_0349 Bcen_2339 Bcen_2340
BCH: 
Bcen2424_0832 Bcen2424_0833 Bcen2424_2953 Bcen2424_2954
BCM: 
Bcenmc03_0804 Bcenmc03_0805 Bcenmc03_2974 Bcenmc03_2975
BCJ: 
BCAL0636(yagS) BCAL0637(xdhA) BCAL3172(xdhB) BCAL3173(xdhA)
BAM: 
Bamb_0711 Bamb_0712 Bamb_2999 Bamb_3000
BAC: 
BamMC406_0728 BamMC406_0729 BamMC406_2862 BamMC406_2863
BMU: 
Bmul_2551 Bmul_2552 Bmul_2947 Bmul_2948
BMJ: 
BMULJ_00286(coxM) BMULJ_00287(coxL) BMULJ_00686(xdhA) BMULJ_00687(xdhA)
BCT: 
GEM_2696 GEM_2697
BXE: 
Bxe_A0949 Bxe_A0950 Bxe_A3885 Bxe_A3886 Bxe_B1319 Bxe_B1320 Bxe_B1943 Bxe_B2225 Bxe_B2226 Bxe_C1224
BPH: 
Bphy_0712 Bphy_0713 Bphy_2421 Bphy_2422 Bphy_4727 Bphy_4728 Bphy_5133 Bphy_5134
BPY: 
Bphyt_0793 Bphyt_0794 Bphyt_3041 Bphyt_3042 Bphyt_4207 Bphyt_4208 Bphyt_5990 Bphyt_5991
BGL: 
bglu_1g06990 bglu_1g07000
BUG: 
BC1001_0499 BC1001_0500 BC1001_2669 BC1001_2670 BC1001_3643 BC1001_3644 BC1001_5210 BC1001_5211
BGE: 
BC1002_0570 BC1002_0571 BC1002_2259 BC1002_2260 BC1002_3400 BC1002_3401 BC1002_3900 BC1002_3901
BGF: 
BC1003_0522 BC1003_0523 BC1003_2638 BC1003_2639 BC1003_3702 BC1003_3703 BC1003_4273 BC1003_4274
BGD: 
bgla_1g07530 bgla_1g07540 bgla_2g24790 bgla_2g24800
BYI: 
BYI23_A006890 BYI23_A006900 BYI23_A021140 BYI23_A021150 BYI23_B009860 BYI23_B009870 BYI23_D009190 BYI23_D009200
BUK: 
MYA_0725 MYA_0726 MYA_2707 MYA_2708
BPX: 
BUPH_00214 BUPH_00215 BUPH_03242 BUPH_03243 BUPH_04385 BUPH_04386 BUPH_05871 BUPH_05872
BPT: 
Bpet3934(yagR) Bpet3935(yagS)
PUT: 
PT7_2999 PT7_3000
AKA: 
TKWG_08795
POL: 
Bpro_1480 Bpro_1481
PNA: 
Pnap_1034 Pnap_1035
AAV: 
Aave_1129 Aave_1130 Aave_1485 Aave_1486 Aave_4012 Aave_4013
AJS: 
Ajs_3102 Ajs_3103
DIA: 
Dtpsy_2448 Dtpsy_2449
AAA: 
Acav_1130 Acav_1131 Acav_1524 Acav_1525 Acav_3911 Acav_3912
ACK: 
C380_05430 C380_05435
VEI: 
Veis_5001 Veis_5002
DAC: 
Daci_3816 Daci_3817 Daci_5909 Daci_5910
DEL: 
DelCs14_0686 DelCs14_0687 DelCs14_3005 DelCs14_3006
VAP: 
Vapar_3811 Vapar_3812 Vapar_3906 Vapar_3907 Vapar_5488 Vapar_5489
VPE: 
Varpa_4513 Varpa_4514 Varpa_4707 Varpa_4708
CTT: 
CtCNB1_0544 CtCNB1_0545
ADN: 
Alide_1070 Alide_1071
ADK: 
Alide2_4034 Alide2_4035
RTA: 
Rta_00240 Rta_00250 Rta_03670 Rta_03680 Rta_04770(yagS) Rta_04780(yagR) Rta_32380 Rta_32390
MPT: 
Mpe_A0798 Mpe_A0799
MMS: 
mma_0506(xdhB) mma_0507(xdhA)
HSE: 
Hsero_3262(xdhA) Hsero_3263(xdhB)
CFU: 
CFU_2113 CFU_2114 CFU_4144(xdhA) CFU_4145(xdhB)
LCH: 
Lcho_3460 Lcho_3461
TIN: 
Tint_1634 Tint_1635
THI: 
THI_1768(xdhB) THI_1769(xdhA)
RGE: 
RGE_39960(xdhB) RGE_39970(xdhA)
AZO: 
azo2211(xdhA) azo2212(xdhB)
TMZ: 
Tmz1t_1338 Tmz1t_1339
GLO: 
Glov_2413
DAS: 
Daes_3249
DAF: 
Desaf_2568 Desaf_2569
BBA: 
Bd2633(xdhA) Bd2634(xdhB)
BBAT: 
Bdt_2548(xdhA) Bdt_2549(xdhB)
BMX: 
BMS_2856(xdhB) BMS_2857(xdhA)
DPS: 
DP1724 DP2531(coxL)
DPR: 
Despr_3165
DSF: 
UWK_01315 UWK_01316
ACP: 
A2cp1_0366
ANK: 
AnaeK_0353
MXA: 
MXAN_3143
MFU: 
LILAB_23480
MSD: 
MYSTI_03638
CCX: 
COCOR_05728(mop)
SUR: 
STAUR_2066(yagR) STAUR_2067 STAUR_2355 STAUR_2356 STAUR_6654
HOH: 
Hoch_4401 Hoch_4402
DTI: 
Desti_0645 Desti_0646 Desti_3923
SFU: 
Sfum_2510 Sfum_2511
MLO: 
mlr1926 mlr1927 mlr5134 mlr5135
MCI: 
Mesci_0369 Mesci_0370 Mesci_2886 Mesci_2887 Mesci_2889 Mesci_2890 Mesci_3779 Mesci_3780
MOP: 
Mesop_0352 Mesop_0353 Mesop_3023 Mesop_3024 Mesop_3261 Mesop_3262 Mesop_3264 Mesop_3265
MAM: 
Mesau_00340 Mesau_00341 Mesau_02468 Mesau_03143 Mesau_03144 Mesau_03147 Mesau_03148 Mesau_05432 Mesau_05433
MES: 
Meso_0580 Meso_0581 Meso_2833 Meso_2834
SME: 
SM_b20132 SM_b20396 SM_b20846(xdhB2) SM_b21011(xdhA2) SM_b21286(xdhA1) SM_b21287(xdhB1) SM_b21338 SM_b21556 SM_b21557 SMa2351 SMa2353
SMK: 
Sinme_3782 Sinme_3783 Sinme_4035 Sinme_4580 Sinme_4581 Sinme_4715 Sinme_4716 Sinme_4792 Sinme_4793 Sinme_4914 Sinme_4915 Sinme_5532 Sinme_5533
SMQ: 
SinmeB_3536 SinmeB_3538 SinmeB_3674 SinmeB_3675 SinmeB_3751 SinmeB_3752 SinmeB_3873 SinmeB_3874 SinmeB_4278 SinmeB_4279 SinmeB_4532 SinmeB_5360 SinmeB_5361
SMX: 
SM11_pC0029 SM11_pC0030 SM11_pD0461(xdhB2) SM11_pD0462(xdhA2) SM11_pD0604 SM11_pD0605 SM11_pD0682 SM11_pD0683 SM11_pD0803(xdhB1) SM11_pD0804(xdhA1) SM11_pD1217 SM11_pD1218 SM11_pD1461
SMI: 
BN406_03527(yagR) BN406_03528(yagS) BN406_05534(XDH1) BN406_05535 BN406_05668(yagS1) BN406_05669 BN406_05745(yagR) BN406_05746(yagS3) BN406_05866(XDH3) BN406_05867 BN406_06276(yagS5) BN406_06277 BN406_06526
SMEG: 
C770_GR4pC0027 C770_GR4pC0028 C770_GR4pC0319 C770_GR4pC0320 C770_GR4pD0452 C770_GR4pD0453 C770_GR4pD0584 C770_GR4pD0585 C770_GR4pD0665 C770_GR4pD0666 C770_GR4pD0789 C770_GR4pD0790 C770_GR4pD1206 C770_GR4pD1207 C770_GR4pD1462
SMEL: 
SM2011_a2351 SM2011_a2353 SM2011_b20132 SM2011_b20395 SM2011_b20396 SM2011_b20846(xdhB2) SM2011_b21011(xdhA2) SM2011_b21286(xdhA1) SM2011_b21287(xdhB1) SM2011_b21338 SM2011_b21556 SM2011_b21557
SMD: 
Smed_4003 Smed_4498 Smed_4499 Smed_4620 Smed_4621 Smed_4734 Smed_4735 Smed_5354
RHI: 
NGR_b01320 NGR_b01330 NGR_b04760 NGR_b04770 NGR_b12680 NGR_b12690 NGR_c23860(xdhA) NGR_c23870(xdhB)
SFH: 
SFHH103_02256(xdhB) SFHH103_05783(xdhB) SFHH103_05784(xdhA)
SFD: 
USDA257_c09800(xdhB) USDA257_c09810(hcrA1) USDA257_c22460(yagR1) USDA257_c22470(yagS1) USDA257_c47480(hcrC) USDA257_c47490(xdhA) USDA257_c51620(yagS2) USDA257_c51630(yagR2)
ATU: 
Atu2309(xdhA) Atu2310(xdhB) Atu5499 Atu5500
ARA: 
Arad_3312(xdhA) Arad_3313(xdhB) Arad_4584 Arad_4585 Arad_7431 Arad_7432 Arad_9877
AVI: 
Avi_2456 Avi_2457 Avi_3320(xdhA) Avi_3321(xdhB) Avi_5106 Avi_5107
AGR: 
AGROH133_07982(xdhA) AGROH133_07983(xdhB) AGROH133_13175 AGROH133_13176
RET: 
RHE_CH03124(xdhA) RHE_CH03125(xdhB)
REC: 
RHECIAT_CH0003283(xdhA) RHECIAT_CH0003284(xdhB)
RLE: 
RL3570(xdhA) RL3571(xdhB) pRL120300(yagR) pRL120301(yagS)
RLT: 
Rleg2_2861 Rleg2_2862
RLG: 
Rleg_3133 Rleg_3135 Rleg_4658 Rleg_4659
RTR: 
RTCIAT899_CH13195(xdhA1) RTCIAT899_CH13200(xdhB1) RTCIAT899_PA00140(yagS) RTCIAT899_PA00145(yagR) RTCIAT899_PC01500(xdhB2) RTCIAT899_PC01505(xdhA2) RTCIAT899_PC07525 RTCIAT899_PC07530
BME: 
BMEI1575 BMEI1576
BMI: 
BMEA_A0386(xdhA) BMEA_A0387(xdhB)
BMZ: 
BM28_A0380(xdhA) BM28_A0381(xdhB)
BMG: 
BM590_A0376 BM590_A0377
BMW: 
BMNI_I0371 BMNI_I0372
BMF: 
BAB1_0377
BMB: 
BruAb1_0375 BruAb1_0376
BMC: 
BAbS19_I03480 BAbS19_I03490
BAA: 
BAA13334_I03361 BAA13334_I03363
BMS: 
BR0349 BR0350
BSI: 
BS1330_I0350 BS1330_I0351
BMT: 
BSUIS_A0381(xdhB)
BSV: 
BSVBI22_A0350 BSVBI22_A0351
BOV: 
BOV_0365(xdhA)
BCS: 
BCAN_A0357(xdhA) BCAN_A0358(xdhB)
BSK: 
BCA52141_I1125 BCA52141_I1127
BMR: 
BMI_I354(xdhA) BMI_I355(xdhB)
BPP: 
BPI_I383(xdhA) BPI_I384(xdhB)
OAN: 
Oant_0451 Oant_0452
BJA: 
blr2218 blr5210 blr5211
BJU: 
BJ6T_65770 BJ6T_65780 BJ6T_76300 BJ6T_76310
BRA: 
BRADO2883 BRADO2884 BRADO5689 BRADO5690 BRADO6664 BRADO6665
BBT: 
BBta_0870 BBta_0871 BBta_6204 BBta_6205
BRS: 
S23_49580 S23_49590 S23_58030 S23_58040
RPB: 
RPB_4511 RPB_4512
RPC: 
RPC_1131 RPC_1132 RPC_4639 RPC_4640
RPD: 
RPD_0914 RPD_0915
RPE: 
RPE_3213
RPX: 
Rpdx1_1071 Rpdx1_1072
NHA: 
Nham_1040 Nham_1041
OCA: 
OCAR_5616 OCAR_5617 OCAR_7366(xdhA) OCAR_7367(xdhB)
OCG: 
OCA5_c07520(xdhB) OCA5_c07530(xdhA1) OCA5_c23830 OCA5_c23840(xdhA2)
OCO: 
OCA4_c07510(xdhB) OCA4_c07520(xdhA1) OCA4_c23820 OCA4_c23830(xdhA2)
AOL: 
S58_07910 S58_07920 S58_19240 S58_19250 S58_21070
XAU: 
Xaut_3759 Xaut_3760
AZC: 
AZC_1400 AZC_1401
SNO: 
Snov_0395 Snov_0396
MEX: 
Mext_0836 Mext_0837 Mext_3666 Mext_3667
MEA: 
Mex_1p0603 Mex_1p0604 Mex_1p3015 Mex_1p3016 Mex_1p3923 Mex_1p3924
MDI: 
METDI0974 METDI0975 METDI1470 METDI1471 METDI3583 METDI4665 METDI4666
MCH: 
Mchl_0796 Mchl_0797 Mchl_1144 Mchl_1145 Mchl_3041 Mchl_3042 Mchl_3959 Mchl_3960
MRD: 
Mrad2831_1354 Mrad2831_1529 Mrad2831_1530 Mrad2831_4262 Mrad2831_4263 Mrad2831_4485 Mrad2831_4486 Mrad2831_5459 Mrad2831_5460
MET: 
M446_0293 M446_0294 M446_2560 M446_2561 M446_2670 M446_2671
MPO: 
Mpop_0053 Mpop_0759 Mpop_0760 Mpop_2932 Mpop_2933 Mpop_3953 Mpop_3954
MNO: 
Mnod_2923 Mnod_2924 Mnod_8336 Mnod_8337
MSL: 
Msil_3588 Msil_3589
HMC: 
HYPMC_3530 HYPMC_3531
PHL: 
KKY_2236 KKY_2237
MSC: 
BN69_3444 BN69_3445
CCR: 
CC_2618
CCS: 
CCNA_02701 CCNA_02702
CAK: 
Caul_3719 Caul_3720
CSE: 
Cseg_1076 Cseg_1077 Cseg_2087 Cseg_2088
PZU: 
PHZ_c0739 PHZ_c0740
AEX: 
Astex_2531 Astex_2532
SIL: 
SPO0653(xdhB) SPO0654(xdhA)
SIT: 
TM1040_0498 TM1040_0499 TM1040_2704 TM1040_2705
RSP: 
RSP_3205 RSP_3206 RSP_3554(xdhA) RSP_3555(xdhB)
RSH: 
Rsph17029_3237 Rsph17029_3238 Rsph17029_3944 Rsph17029_3945
RSQ: 
Rsph17025_3205 Rsph17025_3206 Rsph17025_3947 Rsph17025_3948
RSK: 
RSKD131_3382 RSKD131_3383 RSKD131_3723 RSKD131_3724
RCP: 
RCAP_rcc00791(xdhB) RCAP_rcc00792(xdhA)
JAN: 
Jann_0936 Jann_0937
RDE: 
RD1_4068(xdhA) RD1_4069(xdhB)
RLI: 
RLO149_c004020(xdhB) RLO149_c004030(xdhA)
PDE: 
Pden_4257 Pden_4258
DSH: 
Dshi_2958(xghB) Dshi_2959(xdhA)
KVU: 
EIO_0257(xdhB) EIO_0258(xdhA)
PSF: 
PSE_3181 PSE_3182
PGA: 
PGA1_c28100(xdhA) PGA1_c28110(xdhB)
PGL: 
PGA2_c26100(xdhA) PGA2_c26110(xdhB)
OAT: 
OAN307_c37860(xdhA) OAN307_c37870(xdhB)
OAR: 
OA238_c05020(xdhB) OA238_c05030(xdhA)
HNE: 
HNE_1071 HNE_1072
NPP: 
PP1Y_AT13137 PP1Y_AT13163
SWI: 
Swit_5314 Swit_5315
SPHM: 
G432_12955 G432_12960
SJP: 
SJA_C1-33640(yagR) SJA_C1-33650(yagS)
SCH: 
Sphch_1995 Sphch_1996
SSY: 
SLG_27060 SLG_27070 SLG_30080 SLG_30090
GOX: 
GOX0653 GOX0654 GOX1494
GOH: 
B932_0746 B932_0747 B932_3013 B932_3014
ACR: 
Acry_0509 Acry_0510 Acry_1124 Acry_1154 Acry_1155
AMV: 
ACMV_05840 ACMV_05850 ACMV_07410(xdhA) ACMV_07420(xdhB) ACMV_07700 ACMV_07710
GDI: 
GDI_2002(xdhB) GDI_2003(xdhA)
GDJ: 
Gdia_0225 Gdia_0226
GXY: 
GLX_26890 GLX_26900
APT: 
APA01_12890(xdhB) APA01_12900(xdhA)
APW: 
APA42C_12890(xdhB) APA42C_12900(xdhA)
APF: 
APA03_12890(xdhB) APA03_12900(xdhA)
APU: 
APA07_12890(xdhB) APA07_12900(xdhA)
APG: 
APA12_12890(xdhB) APA12_12900(xdhA)
APQ: 
APA22_12890(xdhB) APA22_12900(xdhA)
APX: 
APA26_12890(xdhB) APA26_12900(xdhA)
APZ: 
APA32_12890(xdhB) APA32_12900(xdhA)
RCE: 
RC1_3069(yagS) RC1_3070(yagR)
AZL: 
AZL_c04690(xdhB) AZL_c04700(xdhB)
ALI: 
AZOLI_p20350 AZOLI_p20351 AZOLI_p30518(xdhA) AZOLI_p30519(xdhB)
ABS: 
AZOBR_110028 AZOBR_110029 AZOBR_p1130173 AZOBR_p150088 AZOBR_p150089 AZOBR_p310327 AZOBR_p310328
TMO: 
TMO_a0304(yagR) TMO_a0305(yagS)
PBR: 
PB2503_11559 PB2503_11564
APB: 
SAR116_1379 SAR116_1380
PGV: 
SL003B_2248(xdhA) SL003B_2249
BSU: 
BSU32470(pucE) BSU32480(pucD) BSU32490(pucC) BSU32500(pucB) BSU32510(pucA)
BCE: 
BC3165 BC3167 BC3168
BCL: 
ABC3740(pucA) ABC3742(pucC) ABC3743(pucD) ABC3744(pucE)
CBO: 
CBO1285(xdhA2) CBO1286(xdhB2)
CBA: 
CLB_1313 CLB_1314
CBH: 
CLC_1323 CLC_1324
CBY: 
CLM_1444 CLM_1445
CBL: 
CLK_0727 CLK_0728
CBK: 
CLL_A0636 CLL_A0637
CBB: 
CLD_3282 CLD_3283
CBI: 
CLJ_B1333 CLJ_B1334
CBT: 
CLH_0597 CLH_0598
CBF: 
CLI_1370 CLI_1371
CBM: 
CBF_1344 CBF_1345
CBJ: 
H04402_01356 H04402_01357
CSH: 
Closa_1023 Closa_1024
AOE: 
Clos_0375
DRM: 
Dred_1504
DOR: 
Desor_1358 Desor_1359
DAI: 
Desaci_2041 Desaci_2042
DMI: 
Desmer_1284 Desmer_1285 Desmer_1861
HMO: 
HM1_2647 HM1_2648(xdhA)
APR: 
Apre_1423 Apre_1424
AWO: 
Awo_c33550(xdhB) Awo_c33560(xdhA2)
CCT: 
CC1_24540 CC1_24550
ROB: 
CK5_30700 CK5_30710
RTO: 
RTO_10910 RTO_10920
OVA: 
OBV_17260(xdhA) OBV_17270(xdhB)
TMR: 
Tmar_1405 Tmar_1406
MTA: 
Moth_1959 Moth_1960 Moth_1999
NTH: 
Nther_0765
HAS: 
Halsa_2108
HHL: 
Halha_1044
MCX: 
BN42_21679(CoxL_1) BN42_21680(CoxM_1)
MSM: 
MSMEG_0684 MSMEG_0685 MSMEG_0870 MSMEG_0871
MSG: 
MSMEI_0667 MSMEI_0668 MSMEI_0850 MSMEI_0851
MUL: 
MUL_4579(coxM_1) MUL_4580(coxL_1)
MVA: 
Mvan_2075 Mvan_2077
MGI: 
Mflv_0283 Mflv_0284
MSP: 
Mspyr1_04910 Mspyr1_04920
MMC: 
Mmcs_0437 Mmcs_0438
MKM: 
Mkms_0447 Mkms_0448
MJL: 
Mjls_0424 Mjls_0425
MMI: 
MMAR_0080(coxL_2) MMAR_0081(coxM_2) MMAR_0835(coxM_1) MMAR_0836(coxL_1)
MLI: 
MULP_00855(coxM_1) MULP_00856(coxL_1)
CVA: 
CVAR_2577(xdhA) CVAR_2578(xdhB)
CHN: 
A605_09885 A605_09890
NBR: 
O3I_035820 O3I_035825
RHA: 
RHA1_ro00134(xdhB) RHA1_ro00135(xdhA)
ROP: 
ROP_02510 ROP_02520
REQ: 
REQ_02730 REQ_02740
GBR: 
Gbro_2560
GOR: 
KTR9_1748 KTR9_1749
SRT: 
Srot_1540 Srot_1541
SCO: 
SCO0690(SCF15.11) SCO0691(SCF15.12) SCO1132(2SCG38.25c) SCO1133(2SCG38.26c) SCO4971(2SCK31.31) SCO4972(2SCK31.32)
SMA: 
SAV_1537 SAV_1539 SAV_7383 SAV_7384
SGR: 
SGR_5077 SGR_5078 SGR_6437 SGR_6438 SGR_6759 SGR_6760
SCB: 
SCAB_4431 SCAB_82101 SCAB_82111 SCAB_88621 SCAB_88631
SSX: 
SACTE_0277 SACTE_0278
SVL: 
Strvi_4184 Strvi_4185 Strvi_4987 Strvi_4988 Strvi_5092 Strvi_6714 Strvi_6715
SCT: 
SCAT_5535 SCAT_5536(yagS) SCAT_p0401(yagS) SCAT_p0402
SCY: 
SCATT_55360 SCATT_55390 SCATT_p13410 SCATT_p13420
SFA: 
Sfla_5992 Sfla_5993 Sfla_6272 Sfla_6273
SBH: 
SBI_08951 SBI_08952
SHY: 
SHJG_0675 SHJG_0676 SHJG_7772 SHJG_7773
SHO: 
SHJGH_0508 SHJGH_0509 SHJGH_7534 SHJGH_7535
SVE: 
SVEN_6843 SVEN_6844
SDV: 
BN159_1656 BN159_1657(yagS1) BN159_8409(yagS3) BN159_8410
SALB: 
XNR_0569 XNR_0570
STRP: 
F750_0277(yagS) F750_0278(yagR) F750_0575(yagR) F750_0576(yagS)
AAI: 
AARI_28790(xdhB) AARI_28800(xdhA)
KRH: 
KRH_21420(xdhB) KRH_21430(xdhA)
BCV: 
Bcav_1676
ICA: 
Intca_1483 Intca_1484
NCA: 
Noca_1636 Noca_1637
NDA: 
Ndas_1845 Ndas_1846 Ndas_2230
NAL: 
B005_2189(xdhB) B005_2190
SRO: 
Sros_3741 Sros_3742
NML: 
Namu_0258 Namu_0259
BSD: 
BLASA_2903(xdhA) BLASA_2904(xdhB)
MMAR: 
MODMU_2231(xdhB) MODMU_2232(xdhA)
SEN: 
SACE_3092(xdhB) SACE_3093(xdhA) SACE_4467(yagS) SACE_4468 SACE_4618 SACE_4619
SVI: 
Svir_27160 Svir_27170
AMD: 
AMED_3039 AMED_3040 AMED_3641 AMED_3642 AMED_3719 AMED_5757
AMN: 
RAM_15460 RAM_15465 RAM_18520 RAM_18525 RAM_18935 RAM_29435
AMM: 
AMES_3007 AMES_3008 AMES_3600 AMES_3601 AMES_3676 AMES_5681
PDX: 
Psed_2359 Psed_2360
SESP: 
BN6_48200 BN6_48210
SAQ: 
Sare_0201 Sare_0202
AMS: 
AMIS_38880 AMIS_38890
ASE: 
ACPL_2776(xdhB) ACPL_2777
CAI: 
Caci_2735 Caci_2736
SSM: 
Spirs_1105 Spirs_2729
TPX: 
Turpa_1286 Turpa_1287
SBU: 
SpiBuddy_2565 SpiBuddy_2566
SGP: 
SpiGrapes_1151 SpiGrapes_1152 SpiGrapes_1779 SpiGrapes_1780
ABA: 
Acid345_0762 Acid345_0763
ACA: 
ACP_2320 ACP_2321
ACM: 
AciX9_1516 AciX9_1517 AciX9_4097 AciX9_4098
GMA: 
AciX8_2375 AciX8_2376 AciX8_3570 AciX8_3571
TSA: 
AciPR4_1971 AciPR4_1972 AciPR4_3169
TRS: 
Terro_0814 Terro_1958 Terro_1959 Terro_2175 Terro_2176 Terro_2324 Terro_2325 Terro_2539
SUS: 
Acid_0355 Acid_0356 Acid_2420 Acid_2421 Acid_3649 Acid_3650
CPI: 
Cpin_2158 Cpin_2159 Cpin_2167 Cpin_2168 Cpin_4333 Cpin_4334 Cpin_6765 Cpin_6766
NKO: 
Niako_0452 Niako_0453
DFE: 
Dfer_1432 Dfer_1433 Dfer_1535 Dfer_1536
SLI: 
Slin_0112 Slin_0113 Slin_2183 Slin_2184 Slin_2369 Slin_2370 Slin_4033
LBY: 
Lbys_0346 Lbys_0347
RSI: 
Runsl_3434 Runsl_3435
FAE: 
FAES_0105(xdhA) FAES_0106 FAES_2525 FAES_2526 FAES_2649 FAES_2650 FAES_4687 FAES_4688
GFO: 
GFO_0442 GFO_0443
FJO: 
Fjoh_4200 Fjoh_4201
ZPR: 
ZPR_2987 ZPR_2988
FBC: 
FB2170_04460 FB2170_04465
STR: 
Sterm_2680 Sterm_2681
IPO: 
Ilyop_0111
OTE: 
Oter_2521 Oter_2522
MIN: 
Minf_2317(xdhB) Minf_2340(xdhA)
IPA: 
Isop_2869 Isop_2870
SACI: 
Sinac_0251 Sinac_6836 Sinac_6837
PHM: 
PSMK_30650(xdhA) PSMK_30660(xdhB)
TAI: 
Taci_0192
AMO: 
Anamo_1345
CYT: 
cce_3509 cce_3510
CYN: 
Cyan7425_0101 Cyan7425_0102
HAO: 
PCC7418_2393 PCC7418_2394
CMP: 
Cha6605_1544 Cha6605_1545
NPU: 
Npun_F2248 Npun_F5027 Npun_F5028
NOP: 
Nos7524_1994 Nos7524_1995
AVA: 
Ava_C0126 Ava_C0127
CALT: 
Cal6303_2541 Cal6303_2542
RIV: 
Riv7116_5585 Riv7116_5586 Riv7116_6497 Riv7116_6498
CEP: 
Cri9333_1480 Cri9333_1481
MIC: 
Mic7113_0405 Mic7113_0406
CTHE: 
Chro_1943 Chro_1944
DRA: 
DR_A0177 DR_A0178 DR_A0231 DR_A0232 DR_A0236 DR_A0237
DGE: 
Dgeo_2603 Dgeo_2604
DPT: 
Deipr_2150 Deipr_2151 Deipr_2594 Deipr_2595
DGO: 
DGo_CA0622(yagR) DGo_CA0623(yagS) DGo_CA0727 DGo_CA0728 DGo_PA0329 DGo_PA0330(xdhB)
DPD: 
Deipe_0080 Deipe_0081
TRA: 
Trad_1510 Trad_1511
MRB: 
Mrub_1453 Mrub_1454
MRE: 
K649_15300 K649_15305
MSV: 
Mesil_1788 Mesil_1789
MPZ: 
Marpi_1145
 » show all
Taxonomy
Reference
1  [PMID:6960894]
  Authors
Battelli MG, Lorenzoni E.
  Title
Purification and properties of a new glutathione-dependent thiol:disulphide oxidoreductase from rat liver.
  Journal
Biochem. J. 207 (1982) 133-8.
  Organism
Rattus norvegicus [GN:rno]
Reference
2  [PMID:4342395]
  Authors
Corte ED, Stirpe F.
  Title
The regulation of rat liver xanthine oxidase. Involvement of thiol groups in the conversion of the enzyme activity from dehydrogenase (type D) into oxidase (type O) and purification of the enzyme.
  Journal
Biochem. J. 126 (1972) 739-45.
  Organism
Rattus norvegicus [GN:rno]
Reference
3  [PMID:14264879]
  Authors
PARZEN SD, FOX AS.
  Title
PURIFICATION OF XANTHINE DEHYDROGENASE FROM DROSOPHILA MELANOGASTER.
  Journal
Biochim. Biophys. Acta. 92 (1964) 465-71.
  Organism
Drosophila melanogaster [GN:dme]
Reference
4  [PMID:4294045]
  Authors
Rajagopalan KV, Handler P.
  Title
Purification and properties of chicken liver xanthine dehydrogenase.
  Journal
J. Biol. Chem. 242 (1967) 4097-107.
  Organism
Gallus gallus [GN:gga]
Reference
5  [PMID:6061702]
  Authors
Smith ST, Rajagopalan KV, Handler P.
  Title
Purification and properties of xanthine dehydroganase from Micrococcus lactilyticus.
  Journal
J. Biol. Chem. 242 (1967) 4108-17.
  Organism
Micrococcus lactilyticus
Reference
6  [PMID:3459393]
  Authors
Ikegami T, Nishino T
  Title
The presence of desulfo xanthine dehydrogenase in purified and crude enzyme preparations from rat liver.
  Journal
Arch. Biochem. Biophys. 247 (1986) 254-60.
Reference
7  [PMID:3294898]
  Authors
Engerson TD, McKelvey TG, Rhyne DB, Boggio EB, Snyder SJ, Jones HP
  Title
Conversion of xanthine dehydrogenase to oxidase in ischemic rat tissues.
  Journal
J. Clin. Invest. 79 (1987) 1564-70.
Reference
8  [PMID:2610112]
  Authors
Saito T, Nishino T, Tsushima K
  Title
Interconversion between NAD-dependent and O2-dependent types of rat liver xanthine dehydrogenase and difference in kinetic and redox properties between them.
  Journal
Adv. Exp. Med. Biol. 253B (1989) 179-83.
Reference
9  [PMID:11341925]
  Authors
Parschat K, Canne C, Huttermann J, Kappl R, Fetzner S.
  Title
Xanthine dehydrogenase from Pseudomonas putida 86: specificity, oxidation-reduction potentials of its redox-active centers, and first EPR characterization.
  Journal
Biochim. Biophys. Acta. 1544 (2001) 151-65.
  Organism
Pseudomonas putida
Reference
10 [PMID:8224915]
  Authors
Ichida K, Amaya Y, Noda K, Minoshima S, Hosoya T, Sakai O, Shimizu N, Nishino T.
  Title
Cloning of the cDNA encoding human xanthine dehydrogenase (oxidase): structural analysis of the protein and chromosomal location of the gene.
  Journal
Gene. 133 (1993) 279-84.
  Organism
Homo sapiens [GN:hsa]
Reference
11 [PMID:11005854]
  Authors
Enroth C, Eger BT, Okamoto K, Nishino T, Nishino T, Pai EF.
  Title
Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: structure-based mechanism of conversion.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 10723-8.
  Organism
Bos taurus [GN:bta]
Reference
12 [PMID:11796116]
  Authors
Truglio JJ, Theis K, Leimkuhler S, Rappa R, Rajagopalan KV, Kisker C.
  Title
Crystal structures of the active and alloxanthine-inhibited forms of xanthine dehydrogenase from Rhodobacter capsulatus.
  Journal
Structure. (Camb). 10 (2002) 115-25.
  Organism
Rhodobacter capsulatus
Reference
13 [PMID:11848841]
  Authors
Hille R.
  Title
The Mononuclear Molybdenum Enzymes.
  Journal
Chem. Rev. 96 (1996) 2757-2816.
  Organism
Rattus norvegicus [GN:rno], Homo sapiens [GN:hsa], Gallus gallus [GN:gga], Drosophila melanogaster [GN:dme], Chlamydomonas reinhardtii [GN:cre], Micrococcus lactilyticus
Reference
14 [PMID:18569334]
  Authors
Taibi G, Di Gaudio F, Nicotra CM
  Title
Xanthine dehydrogenase processes retinol to retinoic acid in human mammary epithelial cells.
  Journal
J. Enzyme. Inhib. Med. Chem. 23 (2008) 317-27.
Reference
15 [PMID:18513323]
  Authors
Nishino T, Okamoto K, Eger BT, Pai EF, Nishino T
  Title
Mammalian xanthine oxidoreductase - mechanism of transition from xanthine dehydrogenase to xanthine oxidase.
  Journal
FEBS. J. 275 (2008) 3278-89.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9054-84-6
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