KEGG   ENZYME: 1.2.99.2Help
Entry
EC 1.2.99.2                 Enzyme                                 
Name
carbon-monoxide dehydrogenase (acceptor);
anaerobic carbon monoxide dehydrogenase;
carbon monoxide oxygenase;
carbon-monoxide dehydrogenase;
carbon-monoxide:(acceptor) oxidoreductase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With other acceptors
BRITE hierarchy
Sysname
carbon-monoxide:acceptor oxidoreductase
Reaction(IUBMB)
CO + H2O + A = CO2 + AH2
Reaction(KEGG)
(other) R07157 R08034
Show
Substrate
CO [CPD:C00237];
H2O [CPD:C00001];
A [CPD:C00028]
Product
CO2 [CPD:C00011];
AH2 [CPD:C00030]
Comment
Contains a [Ni3Fe-4S] cluster and [4Fe-4S] clusters. It uses many electron acceptors, including ferredoxin, methyl viologen and benzyl viologen and flavins, but not pyridine nucleotides. Forms part of a membrane-bound multienzyme complex with EC 1.12.99.6, hydrogenase (acceptor), which catalyses the overall reaction: CO + H2O = CO2 + H2.
Pathway
Nitrotoluene degradation
Methane metabolism
Carbon fixation pathways in prokaryotes
Microbial metabolism in diverse environments
Orthology
K00198  
carbon-monoxide dehydrogenase catalytic subunit
K03518  
carbon-monoxide dehydrogenase small subunit
K03519  
carbon-monoxide dehydrogenase medium subunit
K03520  
carbon-monoxide dehydrogenase large subunit
Genes
ESC: 
EAE: 
EAR: 
KOX: 
CRO: 
PPR: 
PPT: 
AVN: 
SHL: 
TMB: 
AEH: 
Mlg_1562 Mlg_1563 Mlg_1564
AFE: 
Lferr_0919 Lferr_0953
AFR: 
AFE_0776
ACU: 
Atc_m021
AFI: 
Acife_0650
RSO: 
RSc1467 RSc1469
RSC: 
RCFBP_11878(coxS) RCFBP_11880(coxM)
RSL: 
RPSI07_1900(coxS) RPSI07_1902(coxM)
RSN: 
RSPO_c01882(coxS) RSPO_c01885(coxM)
RPI: 
Rpic_1352 Rpic_1354
RPF: 
Rpic12D_1416 Rpic12D_1418
REU: 
Reut_A0423 Reut_A0425 Reut_A3074 Reut_A3075 Reut_B3595 Reut_B3596 Reut_B3790 Reut_B3791
REH: 
H16_A0437(coxM1) H16_A0439(coxS1) H16_A1724(h16_A1724) H16_A3369(h16_A3369) H16_A3370(coxS5) H16_B0744(hcrB) H16_B0745(hcrC) H16_B0815(qorL2) H16_B0816 H16_B0817
RME: 
Rmet_0363(coxM) Rmet_0365(coxS)
CTI: 
RALTA_A0379(cooxM) RALTA_A0381(coxS) RALTA_A2828(xdhB1) RALTA_A2829(xdhC1) RALTA_B0581(hbaD) RALTA_B0582(hbaB)
CNC: 
CNE_1c04580(coxM) CNE_1c04600(coxS1) CNE_2c06910(hcrB) CNE_2c06920(hcrC) CNE_2c07640(cutM) CNE_2c07650(cutS)
BXE: 
Bxe_A2144 Bxe_A2145 Bxe_A2146(coxL2) Bxe_A4351 Bxe_A4353 Bxe_B0074 Bxe_B0075 Bxe_B0076 Bxe_B1053 Bxe_B1054 Bxe_B1055 Bxe_B2530 Bxe_B2532 Bxe_B2533 Bxe_C0029 Bxe_C0030 Bxe_C0031(coxL)
BPH: 
Bphy_0093 Bphy_0095 Bphy_4547 Bphy_4548 Bphy_4549
BPY: 
Bphyt_0368 Bphyt_0370
BUG: 
BC1001_0107 BC1001_0109
BGE: 
BC1002_0087 BC1002_0089
BGF: 
BC1003_0129 BC1003_0131 BC1003_5907 BC1003_5909
BYI: 
BYI23_A027300 BYI23_A027320 BYI23_C001530 BYI23_C001540 BYI23_C003160 BYI23_C003170 BYI23_C013280 BYI23_C013300 BYI23_D006320 BYI23_D006330
BPX: 
BUPH_04010 BUPH_04012
BPE: 
BP0590 BP0591 BP0684A BP0685
BPC: 
BPTD_0598 BPTD_0599 BPTD_0692
BPER: 
BN118_3020 BN118_3477 BN118_3478
BPA: 
BPP0278 BPP0279 BPP0388 BPP0389
BPAR: 
BN117_0277 BN117_0385 BN117_0386
BBR: 
BB0281 BB0282 BB0390 BB0391 BB0392
BBM: 
BN115_0267 BN115_0375 BN115_0376
BBH: 
BN112_3022 BN112_3023 BN112_3135
BAV: 
BAV1575(cutS) BAV1576(cutM) BAV1577(cutL) BAV2737(coxS) BAV2738(coxM)
AXY: 
AXYL_02473 AXYL_02474(cutM) AXYL_02475
AKA: 
TKWG_00665 TKWG_00670 TKWG_13605 TKWG_13610
POL: 
Bpro_0576 Bpro_0578 Bpro_3394
ACK: 
C380_17055 C380_17890 C380_17900
VEI: 
Veis_4542 Veis_4544
DAC: 
Daci_2248 Daci_2250
DEL: 
DelCs14_2872 DelCs14_2873 DelCs14_4437 DelCs14_4439
VAP: 
Vapar_1593 Vapar_1595 Vapar_2379 Vapar_4285 Vapar_4286 Vapar_4287
VPE: 
Varpa_1755 Varpa_1757 Varpa_2562
CTT: 
CtCNB1_1594 CtCNB1_1595 CtCNB1_3513 CtCNB1_3515
ADN: 
Alide_1972 Alide_1974
ADK: 
Alide2_2225 Alide2_2227 Alide2_4321 Alide2_4322
RTA: 
Rta_01170 Rta_13370 Rta_13390
MMS: 
mma_0774(cutL) mma_0775(cutM) mma_0776
RGE: 
RGE_39240(coxS) RGE_39260(coxM)
BPRC: 
D521_1167 D521_1168
CCV: 
CCV52592_1131(cooS)
CCO: 
CCC13826_0236(cooS)
GSU: 
GSU2098(cooS)
GME: 
Gmet_1902(cooS) Gmet_2134(pcmR) Gmet_2135(pcmS)
GUR: 
Gura_0618
GLO: 
Glov_2414
GBM: 
Gbem_0072(cooS-2) Gbem_1736(cooS-1)
GEO: 
Geob_0107 Geob_0108 Geob_0362 Geob_1046
GEM: 
GM21_2836 GM21_2837
PCA: 
Pcar_0057(cooS-2) Pcar_0888(cooS-1)
PPD: 
Ppro_1445 Ppro_1513
DVU: 
DVU2098(cooS)
DVL: 
Dvul_1133
DVM: 
DvMF_2233
DVG: 
Deval_1949
DDE: 
Dde_3028
DDS: 
Ddes_0382
DDN: 
DND132_2520
DMA: 
DMR_19370(xdhC) DMR_25780
DSA: 
Desal_2508
DAS: 
Daes_0529 Daes_3248
DAF: 
Desaf_2031 Desaf_2842
DPI: 
BN4_11185 BN4_11760(cooS) BN4_20190(cooS)
DBA: 
Dbac_0934
DRT: 
Dret_1234
DPS: 
DP2532(coxS)
DAK: 
DaAHT2_0337 DaAHT2_0827
DPR: 
Despr_2751 Despr_3166
DSF: 
UWK_01293 UWK_03164
DOL: 
Dole_1461 Dole_3185
DAL: 
Dalk_0680 Dalk_2379
DAT: 
HRM2_16670(cdhA) HRM2_38000(coxS) HRM2_41010(cdh1) HRM2_43440(cdh2)
DTO: 
TOL2_C00990(cdh1) TOL2_C11820(cdhA) TOL2_C15820(hcrC) TOL2_C15830(hcrB) TOL2_C16060(hcrC2) TOL2_C38110(cooS) TOL2_C41670(hcrB3) TOL2_C41680(hcrC3)
SUR: 
STAUR_5662 STAUR_5663
SCL: 
sce5894
HOH: 
Hoch_1360 Hoch_1361 Hoch_2000 Hoch_2001 Hoch_2002 Hoch_2566 Hoch_2568 Hoch_5970
DAO: 
Desac_0166 Desac_1966 Desac_2050
DTI: 
Desti_0232 Desti_0679 Desti_0680 Desti_1106 Desti_1107 Desti_1813 Desti_1814 Desti_1837 Desti_2397 Desti_4815 Desti_5404 Desti_5405
SFU: 
Sfum_2011 Sfum_2566 Sfum_2875
DBR: 
Deba_0241 Deba_2625
MLO: 
mll1127 mll1129 mll2289 mlr7702
MCI: 
Mesci_2832 Mesci_2833 Mesci_3464 Mesci_3466 Mesci_4864 Mesci_5416 Mesci_5417
MOP: 
Mesop_3071 Mesop_3072 Mesop_3944 Mesop_3946
MAM: 
Mesau_02466 Mesau_02467 Mesau_02937 Mesau_03726 Mesau_03728
MES: 
Meso_0058 Meso_0060 Meso_0907
PLA: 
Plav_2708 Plav_2960 Plav_2962
SME: 
SM_b20130 SM_b20131 SMc03101 SMc03103
SMK: 
Sinme_3044 Sinme_3046 Sinme_4036 Sinme_4037
SMQ: 
SinmeB_2818 SinmeB_2820 SinmeB_4533 SinmeB_4534
SMX: 
SM11_chr3168(coxM2) SM11_chr3170(coxS) SM11_pC0450 SM11_pD1462 SM11_pD1463
SMI: 
BN406_02846 BN406_02848 BN406_04918 BN406_06527 BN406_06528
SMEG: 
C770_GR4Chr3128 C770_GR4Chr3130 C770_GR4pC0070 C770_GR4pC0071 C770_GR4pD1463 C770_GR4pD1464
SMEL: 
SM2011_a2041 SM2011_a5011 SM2011_b20130 SM2011_b20131 SM2011_c03101 SM2011_c03103
SMD: 
Smed_2881 Smed_2883 Smed_4004 Smed_4005
RHI: 
NGR_b02080(coxS) NGR_b02090 NGR_c05960 NGR_c05970 NGR_c30710 NGR_c30730
SFH: 
SFHH103_03096(coxm3) SFHH103_03098(coxS) SFHH103_06732 SFHH103_06733(coxS)
SFD: 
USDA257_c24870 USDA257_c24880(ndhS) USDA257_c55140(cutM) USDA257_c55160(coxS)
ARA: 
Arad_4266(xdhA) Arad_4268(xdhA)
AVI: 
Avi_5434(xdhA)
REC: 
RHECIAT_PB0000049
RLE: 
pRL80023(coxL) pRL80024(coxS)
RTR: 
RTCIAT899_CH16585 RTCIAT899_CH16595
BJA: 
bll3968 bll5664(cooxM) bll5665(cooxS) bll5914 bll6237(cutL) bll6239(cutM) bll7271 blr0335 blr0337 blr3350(cutL) blr3351(cutM) blr3352
BJU: 
BJ6T_02950 BJ6T_02970 BJ6T_18410 BJ6T_18420 BJ6T_34560 BJ6T_34570 BJ6T_40690 BJ6T_40700 BJ6T_63700
BRA: 
BRADO1406 BRADO2857 BRADO2858 BRADO3149 BRADO4584 BRADO4585 BRADO4586 BRADO5140 BRADO6029(coxL) BRADO6030(coxS) BRADO6031(coxM) BRADO6957 BRADO6959
BBT: 
BBta_0572 BBta_0574 BBta_1747(coxM) BBta_1748(coxS) BBta_1749(coxL) BBta_1909 BBta_1911 BBta_2633(coxS) BBta_2634(coxL) BBta_2635(coxM) BBta_3595 BBta_3730 BBta_3731 BBta_3732 BBta_5317 BBta_5318 BBta_5607 BBta_6697
BRS: 
S23_04990 S23_05010 S23_14860 S23_14880 S23_20500(cutM) S23_20510 S23_25890(cooxS) S23_25900(cooxM) S23_45270 S23_60800(coxS) S23_60810(coxM)
RPA: 
RPA1572 RPA2194 RPA3802 RPA3803 RPA3974 RPA4666(coxS) RPA4668(coxM)
RPB: 
RPB_0911 RPB_0913 RPB_1613 RPB_3094 RPB_3095 RPB_3096 RPB_3102 RPB_3103 RPB_3104 RPB_3111 RPB_3112 RPB_3198 RPB_3677 RPB_3678 RPB_3957
RPC: 
RPC_1439 RPC_1632 RPC_3083 RPC_4498 RPC_4528 RPC_4530
RPD: 
RPD_1022 RPD_1024 RPD_1624 RPD_1782 RPD_1783 RPD_2257 RPD_3715
RPE: 
RPE_1460 RPE_1655 RPE_1656 RPE_4323 RPE_4568 RPE_4570
RPT: 
Rpal_1760 Rpal_2488 Rpal_4325 Rpal_4326 Rpal_4497 Rpal_5147 Rpal_5149
RPX: 
Rpdx1_1540 Rpdx1_1541 Rpdx1_4842 Rpdx1_4844
NWI: 
Nwi_1079 Nwi_2204 Nwi_2205
NHA: 
Nham_1307 Nham_1453 Nham_1455 Nham_2606 Nham_2607
OCG: 
OCA5_pHCG300290(coxM) OCA5_pHCG300300(coxS)
OCO: 
OCA4_pHCG3B00290(coxM) OCA4_pHCG3B00300(coxS)
AOL: 
S58_05340 S58_05360 S58_14460 S58_21160 S58_28990 S58_42710 S58_42720 S58_43500 S58_43510 S58_47510 S58_47520 S58_62030 S58_62040
XAU: 
Xaut_0646 Xaut_0647 Xaut_0648
AZC: 
AZC_1820 AZC_2937 AZC_2939
SNO: 
Snov_1561 Snov_1562 Snov_4235 Snov_4236 Snov_4237
MEX: 
Mext_1289 Mext_1290 Mext_1291
MDI: 
METDI1877 METDI1878 METDI1879
MCH: 
Mchl_1451 Mchl_1452 Mchl_1453
MRD: 
Mrad2831_5830 Mrad2831_5831 Mrad2831_5832 Mrad2831_5854 Mrad2831_5855
MET: 
M446_0551 M446_0552 M446_3111 M446_5441 M446_5443 M446_5697 M446_5698 M446_5699
MPO: 
Mpop_1232 Mpop_3560 Mpop_3561
MNO: 
Mnod_1749 Mnod_1751 Mnod_2020 Mnod_2021 Mnod_3165 Mnod_5304
HMC: 
HYPMC_0179(cutS) HYPMC_0180 HYPMC_0249 HYPMC_0251
SIL: 
SPO1518(coxS-1) SPO1520 SPO2397(coxL-2) SPO2398(coxS-2) SPO2399(coxM) SPO2881 SPO3019
SIT: 
TM1040_1705 TM1040_1764 TM1040_1766
RSP: 
RSP_2876 RSP_2878(coxS)
RSH: 
Rsph17029_1522 Rsph17029_1524
RSQ: 
Rsph17025_1142 Rsph17025_1144
RSK: 
RSKD131_1192 RSKD131_1194
JAN: 
Jann_1763 Jann_1766 Jann_2095 Jann_2949
RDE: 
RD1_1758 RD1_2972(coxM) RD1_2974(coxS)
RLI: 
RLO149_c014540 RLO149_c014560 RLO149_c017450(coxM) RLO149_c017460(coxS) RLO149_c032240
DSH: 
Dshi_1210(coxM) Dshi_1211(coxS) Dshi_1212(coxL2) Dshi_2086(coxL3) Dshi_2658 Dshi_2660 Dshi_4200 Dshi_4201 Dshi_4202
PSF: 
PSE_1024(coxS) PSE_1027(coxM)
PGA: 
PGA1_c16210 PGA1_c20860 PGA1_c20880
PGL: 
PGA2_c16040 PGA2_c19700 PGA2_c19720
OAT: 
OAN307_c07520(coxM) OAN307_c07530(coxS) OAN307_c07890 OAN307_c07900 OAN307_c32790 OAN307_c32810
OAR: 
OA238_c08220 OA238_c08230 OA238_c17750(coxS) OA238_c17760(coxM) OA238_c20670 OA238_c20690 OA238_c42720 OA238_c42730
NPP: 
PP1Y_AT21860
SWI: 
Swit_0498 Swit_0499 Swit_0834 Swit_0842
ACR: 
Acry_0075 Acry_0077 Acry_1968 Acry_2175 Acry_2176 Acry_2211
AMV: 
ACMV_00990(coxS) ACMV_01010(coxM) ACMV_24230 ACMV_24240
RRU: 
Rru_A0965 Rru_A0967 Rru_A1427
RRF: 
F11_04970 F11_04980 F11_07370
RCE: 
RC1_1074(coxM) RC1_1076(coxS)
MAG: 
amb2881 amb2882 amb3707
AZL: 
AZL_c02250 AZL_c02270(cutM)
ALI: 
AZOLI_p30107(coxS) AZOLI_p30109(coxM)
ABS: 
AZOBR_120019(coxM) AZOBR_120021(coxS) AZOBR_p410013 AZOBR_p410014(coxS)
TMO: 
TMO_1174(cutM) TMO_1176(cutS)
APB: 
SAR116_1386 SAR116_1387 SAR116_2163 SAR116_2165
PGV: 
SL003B_1047 SL003B_1048 SL003B_1473 SL003B_2498 SL003B_2499 SL003B_3013(coxL) SL003B_3014(coxS) SL003B_3015(coxM) SL003B_3711 SL003B_3713
APM: 
HIMB5_00003410 HIMB5_00003430
DIN: 
Selin_2012
BSR: 
I33_3350(pucE)
BSL: 
A7A1_2463
BSH: 
BSU6051_32470(pucE)
BSY: 
I653_15660
BSS: 
BSUW23_15845(pucE)
BST: 
GYO_3545(pucE)
BSO: 
BSNT_04808(pucE)
BSN: 
BSn5_07130
BSQ: 
B657_32470(pucE)
BSUB: 
BEST7613_6386(pucE)
BAO: 
BAMF_3826(RBAM_037010)
BAY: 
RBAM_037010
BAQ: 
BACAU_3715(pucE)
BYA: 
BANAU_3884(pucE)
BAMP: 
B938_18990
BAML: 
BAM5036_3621(ndhS)
BAZ: 
BAMTA208_20160
BQL: 
LL3_04148
BXH: 
BAXH7_04137
BQY: 
MUS_4393
BAMI: 
KSO_000590
BMQ: 
BMQ_2567(pucE)
BMD: 
BMD_2556(pucE)
BSE: 
Bsel_0577
BCO: 
Bcell_2029
BJS: 
MY9_2636 MY9_3280
GTH: 
Geoth_1875
GTE: 
GTCCBUS3UF5_4810
GYC: 
GYMC61_1257
GYA: 
GYMC52_0379
GCT: 
GC56T3_0431
GMC: 
GY4MC1_1807 GY4MC1_2422 GY4MC1_2423
GGH: 
GHH_c03990(pucE1) GHH_c13580 GHH_c13590 GHH_c21840(pucE2)
PJD: 
Pjdr2_3317 Pjdr2_3319
PMS: 
KNP414_03223
PMQ: 
PM3016_3448
PMW: 
B2K_17815
BTS: 
Btus_2010 Btus_2332 Btus_2333 Btus_2630 Btus_2632
CAC: 
CA_C0116 CA_C2498
CAE: 
SMB_G0117(cooS) SMB_G2533
CAY: 
CEA_G0117 CEA_G2512
CTC: 
CTC01156
CNO: 
NT01CX_0669(cooS)
CTH: 
Cthe_2801
CTX: 
Clo1313_0390
CBO: 
CBO0260(xdhC1) CBO1331 CBO2218
CBA: 
CLB_0304 CLB_1315 CLB_1359 CLB_2157
CBH: 
CLC_0319 CLC_1325 CLC_1369
CBY: 
CLM_1446 CLM_1506 CLM_2421
CBL: 
CLK_0729 CLK_0775 CLK_1658 CLK_3442
CBK: 
CLL_A0638 CLL_A3327
CBB: 
CLD_0498 CLD_2358 CLD_3226 CLD_3281
CBI: 
CLJ_B1335 CLJ_B1446 CLJ_B2428
CBN: 
CbC4_2402(cooS)
CBT: 
CLH_0599 CLH_3081
CBF: 
CLI_0333 CLI_1372 CLI_1426 CLI_2267
CBM: 
CBF_0301 CBF_1346 CBF_1402 CBF_2255
CBJ: 
H04402_00251 H04402_01358 H04402_01401 H04402_02230
CBE: 
Cbei_1985 Cbei_3020 Cbei_5054
CKL: 
CKL_2148
CKR: 
CKR_1887
CPY: 
Cphy_0060 Cphy_1517
CCE: 
Ccel_0438 Ccel_2918
CLJ: 
CLJU_c09110(cooS1) CLJU_c17910(cooS2) CLJU_c23600(coxS) CLJU_c23610(coxM) CLJU_c23890(xdhA) CLJU_c29930 CLJU_c37670(codH)
CSH: 
Closa_0659 Closa_0921 Closa_1025 Closa_2309
CCB: 
Clocel_0365 Clocel_1516 Clocel_2587 Clocel_4231
CLS: 
CXIVA_04090
CLB: 
Clo1100_1430 Clo1100_3687
CCL: 
Clocl_0520 Clocl_0806
CAD: 
Curi_c06440(cooS) Curi_c10820 Curi_c19430 Curi_c23910(xdhC1)
CSR: 
Cspa_c16740(cooS1) Cspa_c21120(cooS2) Cspa_c57670(cooS3)
CSS: 
Cst_c19650(cooS1)
CSD: 
Clst_1883
CDF: 
CD630_01740(cooS) CD630_07160(cooS) CD630_20880(xdhC2)
CDC: 
CD196_0188 CD196_0661(cooS) CD196_1945(xdhC) CD196_1952(cutS) CD196_1964
CDL: 
CDR20291_0175 CDR20291_0643(cooS) CDR20291_1988(xdhC) CDR20291_1995(cutS) CDR20291_2007
CDG: 
CDBI1_00950 CDBI1_03420 CDBI1_10060 CDBI1_10095 CDBI1_10155
CST: 
CLOST_1160
AMT: 
Amet_0681 Amet_1177 Amet_2016 Amet_3764 Amet_4570
AOE: 
Clos_0376 Clos_0877 Clos_0878
SWO: 
Swol_1136 Swol_1818
DSY: 
DSY1653 DSY2630 DSY4173 DSY4442
DHD: 
Dhaf_0882 Dhaf_1166 Dhaf_2798 Dhaf_3792
DDH: 
Desde_1134 Desde_2256 Desde_3264
DDL: 
Desdi_0655 Desdi_0934 Desdi_1922 Desdi_3272
DRM: 
Dred_0652 Dred_1503 Dred_2773
DAE: 
Dtox_1270 Dtox_2327 Dtox_2933 Dtox_3780
DCA: 
Desca_0349 Desca_1148 Desca_1990
DKU: 
Desku_1492 Desku_2150 Desku_2787
DRU: 
Desru_0859 Desru_3320
PTH: 
PTH_1539(CoxS) PTH_1540(CoxM) PTH_1579(CoxS)
DAU: 
Daud_0870
TJR: 
TherJR_1157 TherJR_1937 TherJR_2144 TherJR_2959
SGY: 
Sgly_2814
DOR: 
Desor_0421 Desor_0443 Desor_0444 Desor_0818 Desor_1360 Desor_1380 Desor_1381 Desor_2187 Desor_3116 Desor_3274 Desor_4181 Desor_4315 Desor_4446 Desor_4479
DAI: 
Desaci_0260 Desaci_0709 Desaci_1022 Desaci_2043 Desaci_2061 Desaci_2975
DMI: 
Desmer_0456 Desmer_0840 Desmer_1286 Desmer_1307 Desmer_1308 Desmer_1790 Desmer_2153 Desmer_2536 Desmer_3209 Desmer_3478
DED: 
DHBDCA_p230(cooS1)
DEC: 
DCF50_p290(cooS1)
FMA: 
FMG_0505
EEL: 
EUBELI_01494
ERE: 
EUBREC_3155
ERT: 
EUR_06050
ERA: 
ERE_13450
ELM: 
ELI_3603
AWO: 
Awo_c10740(acsA) Awo_c11860(xdhC) Awo_c19050(cooS)
RIX: 
RO1_14790
RIM: 
ROI_22700
CCT: 
CC1_16880 CC1_24570
RAL: 
Rumal_3736
RUM: 
CK1_05420 CK1_12690
ROB: 
CK5_28700 CK5_31120
RTO: 
RTO_08580 RTO_10930
FPR: 
FP2_06970
FPA: 
FPR_30810
OVA: 
OBV_12080 OBV_17280(xdhC)
TMR: 
Tmar_0544 Tmar_0546 Tmar_1479 Tmar_1480 Tmar_1490 Tmar_1491 Tmar_1492
SAY: 
TPY_1081 TPY_1082(yagT) TPY_2010(ygeT) TPY_2218(cutL) TPY_2220(cutM) TPY_2900(cutM) TPY_2901(coxS) TPY_3602(cutM) TPY_3604(coxS)
SAP: 
Sulac_0484 Sulac_0485 Sulac_0486 Sulac_0986 Sulac_0987 Sulac_1315 Sulac_1317 Sulac_2199 Sulac_2568 Sulac_2569
BPRS: 
CK3_12390
BPRL: 
CL2_20270
TTE: 
TTE1708
CHY: 
CHY_0034(cooSV) CHY_0085(cooSII) CHY_0690(coxM) CHY_0691 CHY_0736(cooSIV) CHY_1824(cooSI)
TEP: 
TepRe1_0411 TepRe1_0548
TAE: 
TEPIRE1_4570 TEPIRE1_6120
MTA: 
Moth_1203 Moth_1961 Moth_1972
ADG: 
Adeg_0335
TPZ: 
Tph_c05730(cooS1) Tph_c13580(cooS) Tph_c15180(acsB)
CSC: 
Csac_0400
CHD: 
Calhy_0239
CKI: 
Calkr_0175
CLC: 
Calla_2155
TOC: 
Toce_0335 Toce_0761 Toce_0800
TNR: 
Thena_0036
NTH: 
Nther_0766 Nther_0860 Nther_2152 Nther_2153
HAS: 
Halsa_2103 Halsa_2107
AAR: 
Acear_0457 Acear_0459 Acear_0983 Acear_1305
HHL: 
Halha_1045 Halha_1049 Halha_1234
VPR: 
Vpar_0209 Vpar_0285
SSG: 
Selsp_2016
SRI: 
SELR_14500
MED: 
MELS_0172
MHG: 
MHY_25210
EUC: 
EC1_03630
MTU: 
Rv0373c Rv0374c Rv0375c
MTV: 
RVBD_0373c RVBD_0374c RVBD_0375c
MTC: 
MT0388 MT0389 MT0390
MRA: 
MRA_0382 MRA_0383 MRA_0384
MTF: 
TBFG_10378 TBFG_10379 TBFG_10380
MTB: 
TBMG_00377 TBMG_00378 TBMG_00379
MTK: 
TBSG_00380 TBSG_00381 TBSG_00382
MTZ: 
TBXG_000375 TBXG_000376 TBXG_000377
MTG: 
MRGA327_02355 MRGA327_02360 MRGA327_02365
MTI: 
MRGA423_02350 MRGA423_02355
MTE: 
CCDC5079_0350 CCDC5079_0351 CCDC5079_0352
MTL: 
CCDC5180_0346 CCDC5180_0347 CCDC5180_0348
MTO: 
MTCTRI2_0380 MTCTRI2_0381 MTCTRI2_0382
MTD: 
UDA_0373c UDA_0374c UDA_0375c
MTN: 
ERDMAN_0414 ERDMAN_0415
MTJ: 
J112_02005 J112_02010
MTUB: 
MT7199_0380 MT7199_0381
MBO: 
Mb0380c Mb0381c Mb0382c
MBB: 
BCG_0411c BCG_0412c BCG_0413c
MBT: 
JTY_0381 JTY_0382 JTY_0383
MBM: 
BCGMEX_0381c BCGMEX_0382c BCGMEX_0383c
MBK: 
K60_003940 K60_003950
MAF: 
MAF_03750 MAF_03760 MAF_03770
MCE: 
MCAN_03741 MCAN_03751 MCAN_03761
MCQ: 
BN44_10415(coxS) BN44_10416(CoxM)
MCV: 
BN43_10406(cutL) BN43_10407(coxS) BN43_10408(CoxM)
MCX: 
BN42_20100(cutL) BN42_20101(coxS) BN42_20102(CoxM)
MCZ: 
BN45_10415(cutL) BN45_10416(coxS) BN45_10417(CoxM)
MSM: 
MSMEG_0744 MSMEG_0745 MSMEG_0746 MSMEG_5880 MSMEG_5882
MSG: 
MSMEI_0728 MSMEI_0729 MSMEI_0730 MSMEI_2402 MSMEI_2403 MSMEI_2877 MSMEI_5723 MSMEI_5724
MSA: 
Mycsm_00509 Mycsm_00511 Mycsm_04276 Mycsm_05720 Mycsm_05721
MUL: 
MUL_0115(coxL) MUL_0116(coxS) MUL_0587(coxM_2) MUL_0588(coxL_2)
MVA: 
Mvan_5183 Mvan_5185 Mvan_5186
MGI: 
Mflv_1570 Mflv_1571 Mflv_1573
MSP: 
Mspyr1_09540 Mspyr1_09550
MMC: 
Mmcs_0489 Mmcs_0490 Mmcs_0491 Mmcs_4602 Mmcs_4603
MKM: 
Mkms_0500 Mkms_0501 Mkms_0502 Mkms_4688 Mkms_4690 Mkms_4691
MJL: 
Mjls_0478 Mjls_0479 Mjls_0480 Mjls_4985
MMI: 
MMAR_0621(coxS_3) MMAR_0622(coxM_3) MMAR_0655(coxM) MMAR_0656(coxS) MMAR_0657(coxL)
MRH: 
MycrhN_0072 MycrhN_2355 MycrhN_2356
MCB: 
Mycch_4547 Mycch_4548
MLI: 
MULP_00617(coxS_3) MULP_00618(coxM_3) MULP_00646(coxM) MULP_00647(coxS) MULP_00648(coxL)
NBR: 
O3I_016190
RHA: 
RHA1_ro03489 RHA1_ro03490 RHA1_ro03491 RHA1_ro04975 RHA1_ro04977 RHA1_ro05230 RHA1_ro05231 RHA1_ro05232
RER: 
RER_58770 RER_58780
ROP: 
ROP_27510(kdhM) ROP_27520(kdhB) ROP_27560(ndhB) ROP_32830 ROP_32840 ROP_38560 ROP_50420 ROP_50440 ROP_52770 ROP_52780 ROP_52790
REQ: 
REQ_30440 REQ_30450 REQ_30460 REQ_32080 REQ_32090
GBR: 
Gbro_4315 Gbro_4317
SCO: 
SCO6171(SC6C5.07)
SMA: 
SAV_2068
SGR: 
SGR_1354
SCB: 
SCAB_19251
SSX: 
SACTE_5405
SVL: 
Strvi_2394 Strvi_4353 Strvi_4354 Strvi_4763 Strvi_4764 Strvi_4765
SCT: 
SCAT_4759
SCY: 
SCATT_47520
SFA: 
Sfla_1090
SBH: 
SBI_01572 SBI_01573 SBI_02975
SHY: 
SHJG_7238 SHJG_8356 SHJG_8357
SHO: 
SHJGH_6998 SHJGH_8117 SHJGH_8118
SVE: 
SVEN_5953
SDV: 
BN159_1011 BN159_1013(cutM) BN159_2152
SALB: 
XNR_0365 XNR_0657
STRP: 
F750_5751
KSK: 
KSE_63920
ART: 
Arth_2039 Arth_2040 Arth_2041
AAU: 
AAur_1922
ARR: 
ARUE_113p00040(meqA) ARUE_113p00050(meqB) ARUE_c20550
BCV: 
Bcav_1675
ICA: 
Intca_0111 Intca_0113
NCA: 
Noca_0222 Noca_0223 Noca_0224 Noca_0230 Noca_1489 Noca_1490 Noca_1491 Noca_3968 Noca_3970 Noca_4273
TFU: 
Tfu_2586 Tfu_2587
NDA: 
Ndas_2225
NAL: 
B005_4597
TCU: 
Tcur_4234 Tcur_4236
SRO: 
Sros_1218 Sros_1220 Sros_2775 Sros_6668 Sros_6669
FRE: 
Franean1_3208 Franean1_3209 Franean1_3211 Franean1_4699 Franean1_4710 Franean1_4711 Franean1_5683
FRI: 
FraEuI1c_2745 FraEuI1c_2746 FraEuI1c_5530 FraEuI1c_5531
FSY: 
FsymDg_1198
ACE: 
Acel_1637 Acel_1638
NML: 
Namu_4146 Namu_4148 Namu_5284 Namu_5285 Namu_5287 Namu_5356 Namu_5357
GOB: 
Gobs_0170 Gobs_0171 Gobs_3388 Gobs_4663 Gobs_4664 Gobs_4923 Gobs_4925
BSD: 
BLASA_0146(coxS3) BLASA_0147(coxM3) BLASA_1355(coxS1) BLASA_1356(coxM1) BLASA_1461(coxM5) BLASA_1462(coxS5) BLASA_4798(coxM2) BLASA_4800(coxS2)
MMAR: 
MODMU_0165(coxS) MODMU_0166(coxM) MODMU_0208(xdhC) MODMU_2394 MODMU_2395 MODMU_5067(coxM) MODMU_5068(coxS) MODMU_5366(coxM) MODMU_5368(coxS)
SEN: 
SACE_0536 SACE_0538 SACE_1160 SACE_1161 SACE_1162 SACE_4017 SACE_4018 SACE_4019 SACE_4020 SACE_4873 SACE_4874 SACE_5140
SVI: 
Svir_13110 Svir_13130 Svir_20080 Svir_20090 Svir_20900 Svir_20910
TBI: 
Tbis_0643 Tbis_0645 Tbis_1335 Tbis_2229 Tbis_2230
AMD: 
AMED_1870(coxS) AMED_1872(cutM) AMED_1920(coxS) AMED_4584(coxS) AMED_5244(cutM) AMED_5245(coxS)
AMN: 
RAM_09490 RAM_09500 RAM_09740 RAM_23340 RAM_26710 RAM_26715
AMM: 
AMES_1856(coxS) AMES_1858(cutM) AMES_1905(coxS) AMES_4529(coxS) AMES_5181(cutM) AMES_5182(coxS)
PDX: 
Psed_1762 Psed_2251 Psed_2500 Psed_2561 Psed_2652 Psed_2653 Psed_2654 Psed_2656 Psed_2657 Psed_2658 Psed_2960 Psed_5674 Psed_5676 Psed_5697 Psed_5698 Psed_5930 Psed_5931 Psed_6215 Psed_6470 Psed_6471 Psed_6474 Psed_6475
SESP: 
BN6_04870(coxS1) BN6_04890 BN6_30010(coxS3) BN6_44840 BN6_44850
MAU: 
Micau_1915 Micau_1916 Micau_1917
MIL: 
ML5_2022 ML5_2023 ML5_2024
AMS: 
AMIS_56940 AMIS_57810 AMIS_57820 AMIS_57830
ASE: 
ACPL_4975
CAI: 
Caci_1871 Caci_1872 Caci_4735
SNA: 
Snas_2540
RXY: 
Rxyl_0111 Rxyl_0113 Rxyl_1872 Rxyl_1874 Rxyl_2837
CWO: 
Cwoe_3025 Cwoe_3026 Cwoe_3027 Cwoe_3871 Cwoe_3872 Cwoe_4071 Cwoe_4104 Cwoe_4105 Cwoe_4114 Cwoe_4115
AFO: 
Afer_1568 Afer_1570
AYM: 
YM304_25330 YM304_33300 YM304_33320
TDE: 
TDE0727
TSU: 
Tresu_1062
TBE: 
Trebr_1753
TAZ: 
TREAZ_0663 TREAZ_1535(cooS_2) TREAZ_1650(cooS_1)
TPI: 
TREPR_2359 TREPR_3069(cooS)
SSM: 
Spirs_1181 Spirs_1390 Spirs_2044 Spirs_2730 Spirs_2732 Spirs_2733
STA: 
STHERM_c08110
STQ: 
Spith_1359
SCD: 
Spica_0615 Spica_1450
SFC: 
Spiaf_2223
BHY: 
BHWA1_00061(coxS)
BRM: 
Bmur_2647
BPO: 
BP951000_0719
BPJ: 
B2904_orf2098
BPIP: 
BPP43_11560
BPW: 
WESB_2039
BIP: 
Bint_1940(coxS)
SBU: 
SpiBuddy_2598 SpiBuddy_2599
SGP: 
SpiGrapes_0208 SpiGrapes_0209 SpiGrapes_0901 SpiGrapes_1153 SpiGrapes_3123 SpiGrapes_3154
TRS: 
Terro_0849
SUS: 
Acid_2225 Acid_2227
RMR: 
Rmar_0528 Rmar_0530 Rmar_2764 Rmar_2765 Rmar_2766
RMG: 
Rhom172_0532 Rhom172_0534 Rhom172_2783 Rhom172_2784 Rhom172_2785
NKO: 
Niako_0795 Niako_0797 Niako_5158 Niako_5159 Niako_5160
HHY: 
Halhy_2823 Halhy_2825 Halhy_5285 Halhy_5286 Halhy_5287
FAE: 
FAES_4895(cutM) FAES_4897
STR: 
Sterm_2679
IPO: 
Ilyop_0112 Ilyop_0132 Ilyop_1092
PSL: 
Psta_3686 Psta_3687
TAI: 
Taci_0194 Taci_0415 Taci_0416 Taci_0433
AMO: 
Anamo_1349 Anamo_1355 Anamo_1356 Anamo_1436
SBR: 
SY1_20970
CYP: 
PCC8801_0369
CYH: 
Cyan8802_0377 Cyan8802_0379
CTHE: 
Chro_2162 Chro_3284
CPC: 
Cpar_1193
CPH: 
Cpha266_0149
RRS: 
RoseRS_0340 RoseRS_0342
RCA: 
Rcas_0841 Rcas_0843
CAU: 
Caur_3467 Caur_3469
CAG: 
Cagg_0972 Cagg_0974
CHL: 
Chy400_3736 Chy400_3738
TRO: 
trd_0577 trd_0578 trd_1206 trd_1208 trd_A0068 trd_A0564 trd_A0565 trd_A0566 trd_A0776 trd_A0777
STI: 
Sthe_0231 Sthe_1398 Sthe_1400 Sthe_2308 Sthe_2309 Sthe_2776 Sthe_2777 Sthe_2778 Sthe_2812 Sthe_2813
ATM: 
ANT_05690 ANT_05700 ANT_05770 ANT_05780
CAP: 
CLDAP_06500
DGE: 
Dgeo_1946 Dgeo_1948
DGO: 
DGo_CA2532 DGo_CA2534
MRB: 
Mrub_1378 Mrub_1379 Mrub_1380 Mrub_1525 Mrub_1527
MSV: 
Mesil_2696 Mesil_2698
HTH: 
HTH_0386(coxM) HTH_0388(coxS)
HTE: 
Hydth_0384 Hydth_0386
PMX: 
PERMA_0106(cooS)
TAM: 
Theam_1337
DTE: 
Dester_0417 Dester_0833
TME: 
Tmel_1320 Tmel_1323
TAF: 
THA_1661 THA_1664
PMO: 
Pmob_1733 Pmob_1735 Pmob_1739
KOL: 
Kole_2076
MPZ: 
Marpi_1144 Marpi_1147 Marpi_1677 Marpi_1678
MPG: 
Theba_0935 Theba_1318 Theba_1319
TTR: 
Tter_2232 Tter_2234
DAP: 
Dacet_0134
TID: 
Thein_1422 Thein_2190
TOP: 
TOPB45_0398
CEX: 
CSE_02240 CSE_06770 CSE_07180 CSE_07190
MJA: 
MJ_0728
MVU: 
Metvu_0628
MFS: 
MFS40622_1444
MIG: 
Metig_0288 Metig_0357
MVO: 
Mvol_0200
MAC: 
MA1309(cooS) MA3282(cooS)
MBA: 
Mbar_A3525 Mbar_A3717
MMA: 
MM_0121 MM_2301
MMAZ: 
MmTuc01_0129 MmTuc01_2347
MPY: 
Mpsy_0694
MHZ: 
Metho_1412
MTP: 
Mthe_1216 Mthe_1341
MCJ: 
MCON_2865(cooS)
MHI: 
Mhar_1630
MHU: 
Mhun_1272
MBG: 
BN140_2260(cooS)
MPI: 
Mpet_0907
MBN: 
Mboo_0884
MPL: 
Mpal_0842
MKA: 
MK0536
AFU: 
AF1849(cooS)
FPL: 
Ferp_2369 Ferp_2562
HMA: 
pNG7247(cutC)
HHI: 
HAH_5306(cutC) HAH_5310(iorA)
HWA: 
HQ1942A(coxM) HQ1943A(coxS) HQ1944A(coxL)
HWC: 
Hqrw_2105(coxM1) Hqrw_2106(coxS1) Hqrw_2218(coxS2) Hqrw_2220(coxM2)
NMO: 
Nmlp_3629(coxM) Nmlp_3631(coxS)
HTU: 
Htur_3941 Htur_3943
HVO: 
HVO_B0308 HVO_B0310(coxM)
HJE: 
HacjB3_16016 HacjB3_16106
NOU: 
Natoc_3138 Natoc_3140
PTO: 
PTO1119 PTO1120 PTO1121
TON: 
TON_1018
TGA: 
TGAM_0824(cooS)
TBA: 
TERMP_01153
THA: 
TAM4_1067 TAM4_582
APE: 
APE_0708.1 APE_2213 APE_2219
SMR: 
Smar_0355 Smar_0356
SHC: 
Shell_0448 Shell_0449
DKA: 
DKAM_0376 DKAM_0377 DKAM_0735 DKAM_0736 DKAM_0739
DMU: 
Desmu_0528 Desmu_0529 Desmu_0531 Desmu_0532 Desmu_0781 Desmu_0782
DFD: 
Desfe_0379 Desfe_0380 Desfe_0766 Desfe_0767 Desfe_0769 Desfe_0770
TAG: 
Tagg_0237 Tagg_0238
THG: 
TCELL_0653 TCELL_0654 TCELL_1073 TCELL_1074 TCELL_1086 TCELL_1087
SSO: 
SSO2433(cutC-1) SSO2434(cutB-1) SSO2636(cutB-2) SSO2637(cutC-2) SSO2639(cutA-4)
SOL: 
Ssol_0237 Ssol_0238 Ssol_0448 Ssol_0449 Ssol_2184 Ssol_2185
STO: 
ST0561 ST0562 ST1781 ST1783
SAI: 
Saci_0916 Saci_0917 Saci_2269(cutB) Saci_2270(cutC) Saci_2271(cutA)
SACN: 
SacN8_04440 SacN8_04445 SacN8_11060 SacN8_11065
SACR: 
SacRon12I_04430 SacRon12I_04435 SacRon12I_11305 SacRon12I_11310
SIS: 
LS215_0254 LS215_0255 LS215_2835 LS215_2836 LS215_2837
SIA: 
M1425_0223 M1425_0224 M1425_2673 M1425_2674 M1425_2675
SIM: 
M1627_0223 M1627_0224 M1627_2727 M1627_2728 M1627_2729
SID: 
M164_0242 M164_0243 M164_2658 M164_2659 M164_2660
SIY: 
YG5714_0227 YG5714_0228 YG5714_0849 YG5714_0850 YG5714_2849 YG5714_2850 YG5714_2851
SIN: 
YN1551_1997 YN1551_1998 YN1551_2830 YN1551_2831 YN1551_3036 YN1551_3037 YN1551_3038
SII: 
LD85_0228 LD85_0229 LD85_2991 LD85_2992 LD85_2993
SIH: 
SiH_0229 SiH_0230 SiH_2627 SiH_2628
SIR: 
SiRe_0222 SiRe_0223 SiRe_2567 SiRe_2568
SIC: 
SiL_0216 SiL_0217 SiL_2515 SiL_2516
MSE: 
Msed_0297 Msed_0298 Msed_0299 Msed_0609 Msed_0610
MCN: 
Mcup_1492 Mcup_1493 Mcup_1768 Mcup_1769
AHO: 
Ahos_2224 Ahos_2225
PAI: 
PAE1935 PAE1936 PAE1939
PIS: 
Pisl_1780 Pisl_1783 Pisl_1784
PCL: 
Pcal_0887 Pcal_0888 Pcal_0889
PAS: 
Pars_2021 Pars_2022 Pars_2023
PYR: 
P186_0191 P186_0192
POG: 
Pogu_0100 Pogu_0101 Pogu_1353 Pogu_1354
TNE: 
Tneu_0795 Tneu_0797 Tneu_0798
TUZ: 
TUZN_0837 TUZN_0838
TTN: 
TTX_0327(coxS_cutS) TTX_0328(coxM_cutM)
VDI: 
Vdis_0710 Vdis_0711
VMO: 
VMUT_1558 VMUT_1559
FFO: 
FFONT_0673 FFONT_0674
KCR: 
Kcr_0762
HAH: 
Halar_1107 Halar_1110 Halar_2675
 » show all
Taxonomy
Reference
1  [PMID:3029096]
  Authors
Bonam D, Ludden PW.
  Title
Purification and characterization of carbon monoxide dehydrogenase, a nickel, zinc, iron-sulfur protein, from Rhodospirillum rubrum.
  Journal
J. Biol. Chem. 262 (1987) 2980-7.
  Organism
Rhodospirillum rubrum [GN:rru]
Reference
2  [PMID:6687458]
  Authors
Diekert G, Ritter M.
  Title
Purification of the nickel protein carbon monoxide dehydrogenase of Clostridium thermoaceticum.
  Journal
FEBS. Lett. 151 (1983) 41-4.
  Organism
Moorella thermoacetica [GN:mta]
Reference
3  [PMID:11593006]
  Authors
Drennan CL, Heo J, Sintchak MD, Schreiter E, Ludden PW.
  Title
Life on carbon monoxide: X-ray structure of Rhodospirillum rubrum Ni-Fe-S carbon monoxide dehydrogenase.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 11973-8.
  Organism
Rhodospirillum rubrum [GN:rru]
Reference
4  [PMID:11509720]
  Authors
Dobbek H, Svetlitchnyi V, Gremer L, Huber R, Meyer O.
  Title
Crystal structure of a carbon monoxide dehydrogenase reveals a [Ni-4Fe-5S] cluster.
  Journal
Science. 293 (2001) 1281-5.
  Organism
Carboxydothermus hydrogenoformans [GN:chy]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
64972-88-9
DBGET integrated database retrieval system