KEGG   ENZYME: 1.3.1.20Help
Entry
EC 1.3.1.20                 Enzyme                                 
Name
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase;
dihydrodiol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
trans-1,2-dihydrobenzene-1,2-diol:NADP+ oxidoreductase
Reaction(IUBMB)
trans-1,2-dihydrobenzene-1,2-diol + NADP+ = catechol + NADPH + H+ [RN:R00814]
Reaction(KEGG)
R00814;
(other) R07015 R09420
Show
Substrate
trans-1,2-dihydrobenzene-1,2-diol [CPD:C04221];
NADP+ [CPD:C00006]
Product
catechol [CPD:C00090];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Pathway
Metabolism of xenobiotics by cytochrome P450
Orthology
K00078  
dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP)
K00212  
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
Genes
HSA: 
1109(AKR1C4) 1645(AKR1C1) 1646(AKR1C2) 27294(DHDH)
PTR: 
450274(AKR1C4) 456194(DHDH)
PPS: 
100991467(DHDH)
GGO: 
101152398(DHDH)
PON: 
100174691(DHDH)
MCC: 
MMU: 
71755(Dhdh)
RNO: 
691002(Dhdh)
CFA: 
403786(DHDH)
AML: 
FCA: 
101101272(DHDH)
BTA: 
617564(DHDH)
SSC: 
397337(SUS2DD)
ECB: 
100051521
MDO: 
100030403
GGA: 
777348
ACS: 
100560732 100562900
XLA: 
444539(dhdh)
XTR: 
100145807(dhdh) 448579(dhdh)
DRE: 
406433(dhdhl) 449558(dhdh)
TRU: 
101067668 101068481
OLA: 
101170260
BFO: 
BRAFLDRAFT_212150 BRAFLDRAFT_212312 BRAFLDRAFT_278468
CIN: 
100186038
SPU: 
581125
DME: 
Dmel_CG3609
DPO: 
Dpse_GA17556
DAN: 
Dana_GF15278
DER: 
Dere_GG24525
DPE: 
Dper_GL19398
DSE: 
Dsec_GM18233 Dsec_GM18234
DSI: 
Dsim_GD22839 Dsim_GD22840
DWI: 
Dwil_GK14982
DYA: 
Dyak_GE15118
DGR: 
Dgri_GH13782
DMO: 
Dmoj_GI17186
DVI: 
Dvir_GJ22204
AGA: 
AgaP_AGAP009945
AAG: 
AaeL_AAEL009951
CQU: 
CpipJ_CPIJ014580
AME: 
412231
NVI: 
100117805(NV15695)
TCA: 
660272 661259
API: 
100160235 100162948
ISC: 
IscW_ISCW009997
NVE: 
NEMVE_v1g172894
HMG: 
100210586
AQU: 
100640874 100640997
NGR: 
NAEGRDRAFT_56213
PTI: 
PHATRDRAFT_25422
TPS: 
THAPSDRAFT_23184 THAPSDRAFT_36572
PIF: 
PITG_14357
 » show all
Taxonomy
Reference
1  [PMID:13651190]
  Authors
AYENGAR PK, HAYAISHI O, NAKAJIMA M, TOMIDA I.
  Title
Enzymic aromatization of 3,5-cyclohexadiene-1,2-diol.
  Journal
Biochim. Biophys. Acta. 33 (1959) 111-9.
  Organism
Oryctolagus cuniculus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37255-32-6
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