KEGG   ENZYME: 2.1.3.6Help
Entry
EC 2.1.3.6                  Enzyme                                 

Name
putrescine carbamoyltransferase;
PTCase;
putrescine synthase;
putrescine transcarbamylase
Class
Transferases;
Transferring one-carbon groups;
Carboxy- and carbamoyltransferases
BRITE hierarchy
Sysname
carbamoyl-phosphate:putrescine carbamoyltransferase
Reaction(IUBMB)
carbamoyl phosphate + putrescine = phosphate + N-carbamoylputrescine [RN:R01399]
Reaction(KEGG)
Substrate
carbamoyl phosphate [CPD:C00169];
putrescine [CPD:C00134]
Product
phosphate [CPD:C00009];
N-carbamoylputrescine [CPD:C00436]
Comment
The plant enzyme also catalyses the reactions of EC 2.1.3.3 ornithine carbamoyltransferase, EC 2.7.2.2 carbamate kinase and EC 3.5.3.12 agmatine deiminase, thus acting as putrescine synthase, converting agmatine [(4-aminobutyl)guanidine] and ornithine into putrescine and citrulline, respectively.
History
EC 2.1.3.6 created 1976
Orthology
K13252  
putrescine carbamoyltransferase
Genes
PPR: 
PLA: 
HMC: 
CAK: 
LMO: 
LMF: 
LMC: 
LMN: 
LMY: 
LMT: 
LMG: 
LMS: 
LMJ: 
LMP: 
LMW: 
LMX: 
LMZ: 
LMOC: 
LMOS: 
LMOO: 
LMOY: 
LMOT: 
LMOA: 
LMOL: 
LMOL312_0044(argF-1)
LMOG: 
LMOE: 
LMOB: 
LMOJ: 
LMOZ: 
LMOD: 
LMOW: 
LMOX: 
LMOQ: 
LMR: 
LIV: 
LII: 
LIW: 
LIA: 
LIO: 
LLA: 
L0113(otcA)
LLK: 
LLKF_1862(pctA)
LLT: 
LLS: 
lilo_1676(otcA)
LLD: 
LLW: 
kw2_1669(pctA)
SMU: 
SMU_262(otcA)
SMJ: 
SMUT: 
SCP: 
LSA: 
LBR: 
LBK: 
LBH: 
LBN: 
LAW: 
PPE: 
PPEN: 
PCE: 
PECL_1708(aguB)
EFA: 
EF0732(argF-2)
EFL: 
EF62_1118(agcB)
EFI: 
EFD: 
EFS: 
EFS1_0578(otcA)
EFN: 
EFQ: 
DR75_2688(argF)
EFM: 
EHR: 
ENE: 
CLJ: 
CAH: 
MMY: 
MSC_0703(arcB)
MMYM: 
MMS_A0772(argF)
MML: 
MLC_6550(arcB)
MCP: 
MCAP_0654(argF)
MLC: 
MSB_A0669(argF)
MLH: 
SHI: 
ELE: 
EYY: 
EGYY_08400(ArgF) EGYY_08440(ArgF) EGYY_08490(ArgF) EGYY_17800(ArgF)
OLS: 
CGO: 
GPA: 
AEQ: 
STR: 
 » show all
Taxonomy
Reference
1  [PMID:4621632]
  Authors
Roon RJ, Barker HA.
  Title
Fermentation of agmatine in Streptococcus faecalis: occurrence of putrescine transcarbamoylase.
  Journal
J. Bacteriol. 109 (1972) 44-50.
  Sequence
[efa:EF0732]
Reference
2  [PMID:6895223]
  Authors
Srivenugopal KS, Adiga PR.
  Title
Enzymic conversion of agmatine to putrescine in Lathyrus sativus seedlings. Purification and properties of a multifunctional enzyme (putrescine synthase).
  Journal
J. Biol. Chem. 256 (1981) 9532-41.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9076-55-5

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