KEGG   ENZYME: 2.3.2.10Help
Entry
EC 2.3.2.10                 Enzyme                                 

Name
UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase;
alanyl-transfer ribonucleate-uridine diphosphoacetylmuramoylpentapeptide transferase;
UDP-N-acetylmuramoylpentapeptide lysine N6-alanyltransferase;
uridine diphosphoacetylmuramoylpentapeptide lysine N6-alanyltransferase;
L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine 6-N-alanyltransferase;
L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine N6-alanyltransferase
Class
Transferases;
Acyltransferases;
Aminoacyltransferases
BRITE hierarchy
Sysname
L-alanyl-tRNAAla:UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine N6-alanyltransferase
Reaction(IUBMB)
L-alanyl-tRNAAla + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine = tRNAAla + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine [RN:R04613]
Reaction(KEGG)
R04613;
(other) R08779
Show
Substrate
L-alanyl-tRNA(Ala) [CPD:C00886];
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine
Product
tRNA(Ala) [CPD:C01635];
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine
Comment
Also acts on L-seryl-tRNASer.
History
EC 2.3.2.10 created 1972, modified 2013
Pathway
Peptidoglycan biosynthesis
Orthology
K05363  
serine/alanine adding enzyme
Genes
LLK: 
LLKF_2319(murM)
LLC: 
LLM: 
llmg_2352(murM)
LLR: 
LLN: 
LLI: 
LLW: 
kw2_2131(murM)
LGR: 
LGV: 
SPY: 
SPZ: 
SPYM: 
SPM: 
SPG: 
SpyM3_0435(murM.1) SpyM3_0846(murM.2)
SPS: 
SPH: 
SPI: 
SPJ: 
SPK: 
SPF: 
SpyM50878(murM) SpyM51352(murM)
SPA: 
SPB: 
STG: 
SOZ: 
Spy49_0518c(murM.1) Spy49_0951c(murM2)
STZ: 
STX: 
SPYA: 
A20_0553c(murM) A20_0956c(murM)
SPYH: 
SPN: 
SPD: 
SPD_0535(murM_fibA)
SPR: 
spr0540(murM)
SPW: 
SPCG_0575(murM)
SPX: 
SNE: 
SPV: 
SNM: 
SJJ: 
SPP: 
SNT: 
SNC: 
SNB: 
SNP: 
SNI: 
SNV: 
SNX: 
SND: 
SNU: 
SPNG: 
SPNE: 
SPNU: 
SPNM: 
SPNO: 
SPNN: 
SAG: 
SAN: 
SAK: 
SGC: 
A964_0540(murM) A964_0541(murM)
SAGS: 
SAGL: 
SAGM: 
SAGI: 
SAGR: 
SAGP: 
SMU: 
SMU_717(murM)
SMC: 
SMJ: 
SMUT: 
STC: 
str1155(murM)
STL: 
stu1155(murM)
STE: 
STN: 
STU: 
STW: 
SSA: 
SSA_0862(murM)
SSK: 
SSUI: 
T15_0381(murM)
SGO: 
SGO_1623(murM)
SEQ: 
SEZ: 
Sez_1015(murM) Sez_1319(murM)
SEZO: 
SEU: 
SUB: 
SUB0607(murM)
SDS: 
SDG: 
SDA: 
GGS_0612(murM) GGS_0917(murM)
SDC: 
SDQ: 
SGA: 
SGG: 
SGT: 
SGGB_1503(murM)
SMB: 
smi_1584(fibA)
SOR: 
SOR_1963(murM)
STK: 
STB: 
SGPB_1404(murM)
SCP: 
SCF: 
SSR: 
STF: 
STJ: 
STD: 
SMN: 
SIF: 
SIE: 
SCIM_0530(murM)
SIB: 
SIR_1111(murM)
SIU: 
SII_1132(murM)
SANG: 
SAIN_0586(murM)
SANC: 
SANR_0598(murM)
SCG: 
SCI_0623(murM)
SCON: 
SCRE_0603(murM)
SCOS: 
SCR2_0603(murM)
SOI: 
SIK: 
SLU: 
SIG: 
SIP: 
EFA: 
EFL: 
EF62_2819(murM)
EFI: 
EFD: 
EFS: 
EFN: 
MPS: 
MPX: 
EUC: 
TPY: 
 » show all
Taxonomy
Reference
1  [PMID:4248527]
  Authors
Plapp R, Strominger JL.
  Title
Biosynthesis of the peptidoglycan of bacterial cell walls. 18. Purification and properties of L-alanyl transfer ribonucleic acid-uridine diphosphate-N-acetylmuramyl-pentapeptide transferase from Lactobacillus viridescens.
  Journal
J. Biol. Chem. 245 (1970) 3675-82.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37257-26-4

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