KEGG   ENZYME: 2.7.7.48Help
Entry
EC 2.7.7.48                 Enzyme                                 

Name
RNA-directed RNA polymerase;
RNA nucleotidyltransferase (RNA-directed);
RNA nucleotidyltransferase (RNA-directed);
RNA-dependent ribonucleate nucleotidyltransferase;
3D polymerase;
PB1 proteins;
PB2 proteins;
phage f2 replicase;
polymerase L;
Q-beta replicase;
phage f2 replicase;
ribonucleic acid replicase;
ribonucleic acid-dependent ribonucleate nucleotidyltransferase;
ribonucleic acid-dependent ribonucleic acid polymerase;
ribonucleic replicase;
ribonucleic synthetase;
RNA replicase;
RNA synthetase;
RNA transcriptase;
RNA-dependent ribonucleate nucleotidyltransferase;
RDRP;
RNA-dependent RNA polymerase;
RNA-dependent RNA replicase;
transcriptase
Class
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
BRITE hierarchy
Sysname
nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)
Reaction(IUBMB)
nucleoside triphosphate + RNAn = diphosphate + RNAn+1 [RN:R00444]
Reaction(KEGG)
Substrate
nucleoside triphosphate [CPD:C00201];
RNAn [CPD:C00046]
Product
diphosphate [CPD:C00013];
RNAn+1 [CPD:C00046]
Comment
Catalyses RNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain de novo. See also EC 2.7.7.6 DNA-directed RNA polymerase.
History
EC 2.7.7.48 created 1981, modified 1982
Orthology
K11699  
RNA-dependent RNA polymerase
Genes
BFO: 
ISC: 
TSP: 
ATH: 
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
CSV: 
RCU: 
POP: 
POPTR_0006s17780g POPTR_0006s26980g(POPTRDRAFT_561891) POPTR_0007s06560g POPTR_0008s13520g(POPTRDRAFT_564678) POPTR_0008s13550g(POPTRDRAFT_820696) POPTR_0010s11560g(POPTRDRAFT_231683) POPTR_0015s08500g(POPTRDRAFT_575133) POPTR_0018s01670g(POPTRDRAFT_779035) POPTR_0303s002201 POPTR_0303s002202
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os01t0197900-01(Os01g0197900) Os01t0198000-01(Os01g0198000) Os01t0527600-01(Os01g0527600) Os02t0736200-01(Os02g0736200) Os04t0465700-01(Os04g0465700)
OBR: 
BDI: 
SBI: 
SORBI_02g020722(SORBIDRAFT_02g020722) SORBI_03g002800(SORBIDRAFT_03g002800) SORBI_03g022060(SORBIDRAFT_03g022060) SORBI_03g022880(SORBIDRAFT_03g022880) SORBI_04g028630(SORBIDRAFT_04g028630) SORBI_06g001590(SORBIDRAFT_06g001590) SORBI_06g019330(SORBIDRAFT_06g019330) SORBI_07g006150(SORBIDRAFT_07g006150) SORBI_10g025950(SORBIDRAFT_10g025950) SORBI_10g025970(SORBIDRAFT_10g025970)
ZMA: 
SITA: 
ATR: 
s00056p00110240(AMTR_s00056p00110240) s00078p00055040(AMTR_s00078p00055040) s00078p00056260(AMTR_s00078p00056260) s00088p00026960(AMTR_s00088p00026960) s00176p00039530(AMTR_s00176p00039530)
SMO: 
PPP: 
CSL: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_558084(AO090020000318)
ANG: 
ANI_1_2480094(An11g09540)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
TMS: 
DSQ: 
SHS: 
PCO: 
ADL: 
LBC: 
CCI: 
SCM: 
SLA: 
DFA: 
DFA_00541(rrpB)
EHI: 
EHI_139420(171.t00022)
EDI: 
TET: 
PTM: 
PIF: 
EHX: 
NGR: 
GLA: 
 » show all
Taxonomy
Reference
1
  Authors
August, J.T., Cooper, S., Shapiro, L. and Zinder, N.D.
  Title
RNA phage induced RNA polymerase.
  Journal
Cold Spring Harbour Symp. Quant. Biol. 28 (1963) 95-97.
Reference
2
  Authors
Haruna, J., Nozu, K., Ohtaka, Y. and Spiegelman, S.
  Title
An RNA "Replicase" induced by and selective for a viral RNA: isolation and properties.
  Journal
Proc. Natl. Acad. Sci. USA 50 (1963) 905-911.
Reference
3
  Authors
Weismann, C., Simon, L. and Ochoa, S.
  Title
Induction by an RNA phage of an enzyme catalyzing incorporation of ribonucleotides into ribonucleic acid.
  Journal
Proc. Natl. Acad. Sci. USA 49 (1963) 407-414.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9026-28-2

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