KEGG   ENZYME: 3.1.1.8Help
Entry
EC 3.1.1.8                  Enzyme                                 
Name
cholinesterase;
pseudocholinesterase;
butyrylcholine esterase;
non-specific cholinesterase;
choline esterase II (unspecific);
benzoylcholinesterase;
choline esterase;
butyrylcholinesterase;
propionylcholinesterase;
anticholineesterase;
BtChoEase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
acylcholine acylhydrolase
Reaction(IUBMB)
an acylcholine + H2O = choline + a carboxylate [RN:R01029]
Reaction(KEGG)
Substrate
acylcholine [CPD:C01777];
H2O [CPD:C00001]
Product
choline [CPD:C00114];
carboxylate [CPD:C00060]
Comment
Acts on a variety of choline esters and a few other compounds.
Orthology
K01050  
cholinesterase
Genes
HSA: 
590(BCHE)
PTR: 
460830(BCHE)
PPS: 
100972372(BCHE)
GGO: 
101135975(BCHE)
PON: 
100174585(BCHE)
MCC: 
700484(BCHE)
MMU: 
12038(Bche)
RNO: 
65036(Bche)
CFA: 
488143(BCHE)
AML: 
FCA: 
493960(BCHE)
BTA: 
534616(BCHE)
SSC: 
100624138
ECB: 
100033901(BCHE)
SHR: 
100930262(BCHE)
OAA: 
100074368(BCHE)
GGA: 
395358(BCHE)
TGU: 
100229708(BCHE)
ACS: 
100555848
XTR: 
100495889
OLA: 
100529181
DPO: 
Dpse_GA10907
BMY: 
Bm1_46735
NVE: 
NEMVE_v1g119959
AFM: 
AFUA_8G04210
 » show all
Taxonomy
Reference
1
  Authors
Augustinsson, K.-B.
  Title
Cholinesterases. A study in comparative enzymology.
  Journal
Acta Physiol. Scand. 15, Suppl. 2 (1948)
Reference
2  [PMID:13638253]
  Authors
AUGUSTINSSON KB, OLSSON B.
  Title
Esterases in the milk and blood plasma of swine. I. Substrate specificity and electrophoresis studies.
  Journal
Biochem. J. 71 (1959) 477-84.
  Organism
Sus scofa [GN:ssc]
Reference
3  [PMID:13032058]
  Authors
KOELLE GB.
  Title
Cholinesterases of the tissues and sera of rabbits.
  Journal
Biochem. J. 53 (1953) 217-26.
  Organism
Oryctolagus cuniculus
Reference
4  [PMID:14885021]
  Authors
NACHMANSOHN D, WILSON IB.
  Title
The enzymic hydrolysis and synthesis of acetylcholine.
  Journal
Adv. Enzymol. Relat. Subj. Biochem. 12 (1951) 259-339.
Reference
5
  Authors
Sawyer, C.H.
  Title
Hydrolysis of choline esters by liver.
  Journal
Science 101 (1945) 385-386.
Reference
6  [PMID:16747753]
  Authors
Strelitz F.
  Title
Studies on cholinesterase: 4. Purification of pseudo-cholinesterase from horse serum.
  Journal
Biochem. J. 38 (1944) 86-8.
  Organism
Equus caballus [GN:ecb]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9001-08-5
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