KEGG ENZYME: 3.4.19.3

ENZYME: 3.4.19.3

Entry

EC 3.4.19.3 Enzyme

Name

pyroglutamyl-peptidase I;
5-oxoprolyl-peptidase;
pyrase;
pyroglutamate aminopeptidase;
pyroglutamyl aminopeptidase;
L-pyroglutamyl peptide hydrolase;
pyrrolidone-carboxyl peptidase;
pyrrolidone-carboxylate peptidase;
pyrrolidonyl peptidase;
L-pyrrolidonecarboxylate peptidase;
pyroglutamidase;
pyrrolidonecarboxylyl peptidase

Class

Hydrolases;
Acting on peptide bonds (peptidases);
Omega peptidases

Reaction(IUBMB)

Release of an N-terminal pyroglutamyl group from a polypeptide, the second amino acid generally not being Pro

Comment

A cysteine peptidase, known from bacteria, plants and animals. The enzyme from bacterial sources is used in protein sequencing, and is the type example of peptidase family C15.

Orthology

K01304

pyroglutamyl-peptidase

Genes

HSA:	54858(PGPEP1)
PTR:	748692(PGPEP1)
PPS:	100977016(PGPEP1)
GGO:	101136733(PGPEP1)
PON:	100440178(PGPEP1)
MCC:	720200(PGPEP1)
MMU:	66522(Pgpep1)
RNO:	290648(Pgpep1)
CFA:	484823(PGPEP1)
AML:	100476778
FCA:	101094575(PGPEP1)
BTA:	615089(PGPEP1)
ECB:	100070946
MDO:	100618797
SHR:	100930504
OAA:	100075202
GGA:	420127(PGPEP1)
TGU:	100226421(PGPEP1L)
ACS:	100553869
XLA:	734766(pgpep1)
XTR:	448426(pgpep1)
DRE:	553547(pgpep1)
TRU:	101074966
OLA:	101168938
BFO:	BRAFLDRAFT_124319
SPU:	581828
DME:	Dmel_CG32147
DPO:	Dpse_GA16713
DAN:	Dana_GF10738
DER:	Dere_GG13680
DPE:	Dper_GL25768
DSE:	Dsec_GM24500
DSI:	Dsim_GD12571
DWI:	Dwil_GK20489
DYA:	Dyak_GE19976
DGR:	Dgri_GH17032
DMO:	Dmoj_GI12237
DVI:	Dvir_GJ11468
AGA:	AgaP_AGAP006964
AAG:	AaeL_AAEL002225
CQU:	CpipJ_CPIJ003514
AME:	726220
NVI:	100120114(NV14389)
API:	100161646
PHU:	Phum_PHUM140860
ISC:	IscW_ISCW015168
CEL:	CELE_M04C9.3(M04C9.3)
CBR:	CBG22181
BMY:	Bm1_11435
TSP:	Tsp_05174
SMM:	Smp_140810
NVE:	NEMVE_v1g212899
TAD:	TRIADDRAFT_63763
AQU:	100638297
ATH:	AT1G23440 AT1G56700
ALY:	ARALYDRAFT_680144
GMX:	100305735 100500630 100784344 100789152
MTR:	MTR_1g084740
CSV:	101215577
RCU:	RCOM_0527850 RCOM_1436150
POP:	POPTR_671512 POPTR_834444
VVI:	100252925 100263616
OSA:	4332921 4344054 4346976
DOSA:	Os03t0367900-01(Os03g0367900) Os07t0639600-01(Os07g0639600) Os09t0396300-01(Os09g0396300)
BDI:	100846889
SBI:	SORBI_01g034440(SORBIDRAFT_01g034440) SORBI_02g040830(SORBIDRAFT_02g040830)
ZMA:	100276484 100281916 100283087
SMO:	SELMODRAFT_169592 SELMODRAFT_229706
PPP:	PHYPADRAFT_55238 PHYPADRAFT_61489
VCN:	VOLCADRAFT_62493
TML:	GSTUM_00004643001
PPL:	POSPLDRAFT_103365 POSPLDRAFT_91248
SCM:	SCHCODRAFT_235837
UMA:	UM02263.1
PGR:	PGTG_01503
NGR:	NAEGRDRAFT_71905
DPP:	DICPUDRAFT_52340
TET:	TTHERM_00349070 TTHERM_00527300
PTM:	GSPATT00011229001 GSPATT00033487001
TBR:	Tb927.4.2670(Tb04.1H19.1350)
TCR:	506635.60
LMA:	LMJF_34_2000(PPI)
LIF:	LINJ_34_1750
LDO:	LDBPK_341750
LMI:	LMXM_33_2000
LBZ:	LBRM_20_1500
PTI:	PHATRDRAFT_43368
TPS:	THAPSDRAFT_5692
EFE:	EFER_2401
YPE:	YPO2703(pcp)
YPK:	y1280
YPA:	YPA_2436
YPN:	YPN_1191
YPM:	YP_2507(pcp1)
YPP:	YPDSF_1568
YPG:	YpAngola_A3594(pcp)
YPZ:	YPZ3_2384(pcp)
YPT:	A1122_12540
YPD:	YPD4_2328(pcp)
YPX:	YPD8_2363(pcp)
YPH:	YPC_3151(pcp)
YPS:	YPTB2905(pcp)
YPI:	YpsIP31758_1120(pcp)
YPY:	YPK_1172
YPB:	YPTS_3018
YEN:	YE2950(pcp)
YEP:	YE105_C1290
YEY:	Y11_18661
ECA:	ECA1354(pcp)
PCT:	PC1_1229
PCC:	PCC21_012610
PWA:	Pecwa_3107
PEC:	W5S_3098
ETA:	ETA_23110(pcp)
EPY:	EpC_24450(pcp)
EPR:	EPYR_02647(pcp)
EAM:	EAMY_1161(pcp)
EAY:	EAM_1165(pcp)
EBI:	EbC_12920(pcp)
ERJ:	EJP617_22840(pcp)
PLU:	plu4303(pcp) plu4418
PAY:	PAU_03889(pcp)
SGL:	SG1848
ENT:	Ent638_1219
ESC:	Entcl_3108
EAE:	EAE_14135
EAR:	ST548_p5915
KPN:	KPN_00725
KPU:	KP1_1680
KPM:	KPHS_15600
KPP:	A79E_3511
KPE:	KPK_3845(pcp)
KPO:	KPN2242_06470
KVA:	Kvar_3646
KOX:	KOX_14555
CKO:	CKO_02452
SPE:	Spro_1260 Spro_2993
SRR:	SerAS9_1232
SRS:	SerAS12_1232
SRA:	SerAS13_1232
SMAF:	D781_1182
SMW:	SMWW4_v1c12240 SMWW4_v1c29980
XBO:	XBJ1_1667
XNE:	XNC1_0769
PAM:	PANA_1167(pcp)
PLF:	PANA5342_3122(pcp)
PAJ:	PAJ_0487(pcp)
PAQ:	PAGR_g2992
PVA:	Pvag_0541(pcp)
PAO:	Pat9b_1108
RAH:	Rahaq_3157
RAQ:	Rahaq2_3187
RAA:	Q7S_15925
ROR:	RORB6_11475
EBF:	D782_3141
VVU:	VV2_1257(pcp)
VVY:	VVA0085
VVM:	VVMO6_03064
VPA:	VPA0587
VPB:	VPBB_A0536
VHA:	VIBHAR_05437
VEX:	VEA_001503
VEJ:	VEJY3_21761
VFI:	VF_1370
VFM:	VFMJ11_1451(pcp)
PFS:	PFLU4174
PFC:	PflA506_3482(pcp)
SAZ:	Sama_0018
PHA:	PSHAa1441
MAH:	MEALZ_4017(pcp)
FTU:	FTT_0296(pcp)
FTF:	FTF0296(pcp)
FTW:	FTW_1789(pcp)
FTR:	NE061598_01670
FTT:	FTV_0275(pcp)
FTG:	FTU_0276 FTU_0359
FTL:	FTL_0207
FTH:	FTH_0202(pcp)
FTA:	FTA_0223(pcp)
FTS:	F92_01155
FTI:	FTS_0203(pcp)
FTM:	FTM_1555(pcp)
FTN:	FTN_0211(pcp)
FCF:	FNFX1_0211
FCN:	FN3523_0197
FPH:	Fphi_0621
FRT:	F7308_0198
TMB:	Thimo_3568
CVI:	CV_3176(pcp1)
RSO:	RSc2165(pcp1) RSp0259(pcp2)
RSC:	RCFBP_11230(pcp)
RSL:	RPSI07_1260(pcp) RPSI07_mp0225(pcp)
RSN:	RSPO_c01272(pcp1) RSPO_m00260(pcp2)
RPI:	Rpic_2368 Rpic_3959
RPF:	Rpic12D_1968 Rpic12D_4072
REU:	Reut_A0092
REH:	H16_A0129(pcp)
RME:	Rmet_0067(pcp1)
CTI:	RALTA_A0071(pcp1)
CNC:	CNE_1c01200(pcp) CNE_BB1p03530(pcp)
BRH:	RBRH_02735
BGD:	bgla_2g06220
RFR:	Rfer_0871
POL:	Bpro_1512
ACK:	C380_05515
DAC:	Daci_5729
DEL:	DelCs14_0871
VAP:	Vapar_4364
VPE:	Varpa_0698 Varpa_5017
CTT:	CtCNB1_0566
RTA:	Rta_10320(pcp)
CFU:	CFU_4186(pcp)
RGE:	RGE_39140(pcp)
BBA:	Bd0879(pcp)
BBAT:	Bdt_0841(pcp)
BEX:	A11Q_939
BMX:	BMS_0945(pcp)
BJA:	bll3047
BJU:	BJ6T_67200
BRA:	BRADO2676
BBT:	BBta_3018
BRS:	S23_49490
RPA:	RPA1828
RPB:	RPB_3543
RPC:	RPC_1753
RPD:	RPD_1921
RPE:	RPE_1845
RPT:	Rpal_2032
RPX:	Rpdx1_3697
NWI:	Nwi_2241
NHA:	Nham_2644
OCA:	OCAR_6647
OCG:	OCA5_c14190(pcp)
OCO:	OCA4_c14190(pcp)
AOL:	S58_49400
XAU:	Xaut_2489
AZC:	AZC_1534
SNO:	Snov_0649
MEX:	Mext_0297
MEA:	Mex_1p0187
MDI:	METDI0170
MCH:	Mchl_0341
MPO:	Mpop_0373
MNO:	Mnod_4590
BID:	Bind_1658
MSL:	Msil_1074
HDN:	Hden_2569
HMC:	HYPMC_3806
RVA:	Rvan_2274
PSF:	PSE_0563(pcp)
SWI:	Swit_0885
ACR:	Acry_2286
AMV:	ACMV_25370(pcp)
RCE:	RC1_2620(pcp)
AZL:	AZL_d03120(pcp)
ALI:	AZOLI_p40458(pcp)
ABS:	AZOBR_10457
BSU:	BSU02650(pcp)
BSR:	I33_0306(pcp)
BSL:	A7A1_1933
BSH:	BSU6051_02650(pcp)
BSY:	I653_01305
BSS:	BSUW23_01360(pcp)
BST:	GYO_0466(pcp)
BSO:	BSNT_00470(pcp)
BSN:	BSn5_12905
BSQ:	B657_02650(pcp)
BSUB:	BEST7613_0264(pcp)
BSX:	C663_0256(pcp)
BLI:	BL02514(pcp)
BLD:	BLi03263(pcp)
BAO:	BAMF_0240(pcp)
BAY:	RBAM_002960(pcp)
BAQ:	BACAU_0237(pcp)
BYA:	BANAU_0238(pcp)
BAMP:	B938_01230
BAML:	BAM5036_0251(pcp)
BAZ:	BAMTA208_01230(pcp)
BQL:	LL3_00250(pcp)
BXH:	BAXH7_00256(pcp)
BQY:	MUS_0251(pcp)
BAMI:	KSO_018185
BAE:	BATR1942_19980
BHA:	BH3631(pcp)
BAN:	BA_3090(pcP)
BAR:	GBAA_3090(pcP)
BAT:	BAS2875
BAH:	BAMEG_1517(pcp)
BAI:	BAA_3141(pcp)
BAX:	H9401_2949
BAL:	BACI_c30380(pcp)
BCE:	BC3063
BCA:	BCE_3116(pcP)
BCZ:	BCZK2805(pcp)
BCR:	BCAH187_A3115(pcP)
BCB:	BCB4264_A3083(pcP)
BCU:	BCAH820_3096(pcP)
BCG:	BCG9842_B2153(pcP)
BCQ:	BCQ_2901
BCX:	BCA_3152(pcp)
BNC:	BCN_2919
BCF:	bcf_15030
BCER:	BCK_19470
BCY:	Bcer98_2056
BTK:	BT9727_2844(pcp)
BTL:	BALH_2757
BTB:	BMB171_C2773(pcP)
BTT:	HD73_2894
BTC:	CT43_CH3056(pcP)
BTF:	YBT020_15315
BTM:	MC28_2263
BTG:	BTB_c31820(pcp)
BTI:	BTG_03955
BTN:	BTF1_12855
BTHT:	H175_ch3105
BWE:	BcerKBAB4_2869
BCL:	ABC3089(pcp)
BPF:	BpOF4_05710(pcp)
BMQ:	BMQ_1094(pcp)
BMD:	BMD_1099(pcp)
BMH:	BMWSH_4136
BSE:	Bsel_1493
BCO:	Bcell_2984
BCK:	BCO26_2604
BAG:	Bcoa_1687
BJS:	MY9_0270
OIH:	OB2539
GTH:	Geoth_2276
GTE:	GTCCBUS3UF5_20450
GYC:	GYMC61_2568 GYMC61_2740
GYA:	GYMC52_1698 GYMC52_1870
GCT:	GC56T3_1783
GMC:	GY4MC1_2192
GGH:	GHH_c19630(pcp)
SAU:	SA2482(pcp)
SAV:	SAV2690(pcp)
SAW:	SAHV_2674(pcp)
SAH:	SaurJH1_2771
SAJ:	SaurJH9_2714
SAM:	MW2610(pcp)
SAS:	SAS2576
SAR:	SAR2772(pcp)
SAC:	SACOL2714(pcp)
SAX:	USA300HOU_2692(pcp)
SAA:	SAUSA300_2623(pcp)
SAO:	SAOUHSC_03025
SAE:	NWMN_2588(pcp)
SAD:	SAAV_2764(pcp)
SUU:	M013TW_2673
SUV:	SAVC_12325
SUH:	SAMSHR1132_25190
SUE:	SAOV_2736
SUJ:	SAA6159_02587(pcp)
SUK:	SAA6008_02749(pcp)
SUC:	ECTR2_2543(pcp)
SUT:	SAT0131_02969
SUQ:	HMPREF0772_10496(pcp)
SUZ:	MS7_2696(pcp)
SUD:	ST398NM01_2736
SUX:	SAEMRSA15_25910(pcp)
SUW:	SATW20_28270(pcp)
SUG:	SAPIG2736(pcp)
SUF:	SARLGA251_24580(pcp)
SAB:	SAB2566(pcp)
SUY:	SA2981_2630(pcp)
SAUB:	C248_2754(pcp)
SAUM:	BN843_27280
SEP:	SE0261
SER:	SERP2317(pcp)
SHA:	SH0293(pcp)
SSP:	SSP0471
SCA:	Sca_1271(pcp)
SLG:	SLGD_00279
SLN:	SLUG_02770(pcp)
SSD:	SPSINT_1971
SDT:	SPSE_0511(pcp)
SWA:	A284_00995
LSP:	Bsph_2127
HHD:	HBHAL_4141(pcp)
MCL:	MCCL_0385
BBE:	BBR47_26520(pcp)
GYM:	GYMC10_3819
AAC:	Aaci_0080
AAD:	TC41_0100(pcp)
SIV:	SSIL_2842
LLC:	LACR_C27
LLM:	llmg_0663(pcp)
LLN:	LLNZ_03435
LLI:	uc509_p6011
SPY:	SPy_0506(pcp)
SPZ:	M5005_Spy_0417(pcp)
SPYM:	M1GAS476_0473(pcp)
SPM:	spyM18_0565(pcp)
SPG:	SpyM3_0355(pcp)
SPS:	SPs1498
SPH:	MGAS10270_Spy0418(pcp)
SPI:	MGAS10750_Spy0430(pcp)
SPJ:	MGAS2096_Spy0436(pcp)
SPK:	MGAS9429_Spy0416(pcp)
SPF:	SpyM51453(pcp)
SPA:	M6_Spy0444
SPB:	M28_Spy0405(pcp)
STG:	MGAS15252_0446(pcp)
SOZ:	Spy49_0425c(pcp)
STZ:	SPYALAB49_000458(pcp)
STX:	MGAS1882_0443(pcp)
SPYA:	A20_0462c(pcp)
SPN:	SP_0860 SP_2060
SPD:	SPD_0753(pcp)
SPR:	spr0762(pcp) spr1871(pcp-truncation) spr1872(pcp-truncation)
SPW:	SPCG_0804(pcp) SPCG_2027
SPX:	SPG_0780 SPG_1975
SNE:	SPN23F_07810(pcp) SPN23F_20830
SPV:	SPH_0959(pcp)
SNM:	SP70585_0895(pcp)
SJJ:	SPJ_0797(pcp1) SPJ_2066(pcp2)
SPP:	SPP_0867(pcp1) SPP_2098(pcp2)
SNT:	SPT_1344(pcp1) SPT_2055(pcp2)
SNC:	HMPREF0837_10056(pcp2) HMPREF0837_11631(pcp1)
SNB:	SP670_1465 SP670_2199
SNP:	SPAP_0828 SPAP_2086
SNI:	INV104_07110(pcp) INV104_17760
SNV:	SPNINV200_07560(pcp)
SNX:	SPNOXC_07710(pcp)
SND:	MYY_1339 MYY_1979
SNU:	SPNA45_01169(pcp)
SPNG:	HMPREF1038_00871(pcp) HMPREF1038_02057
SPNE:	SPN034156_18190(pcp)
SPNU:	SPN034183_07710(pcp)
SPNM:	SPN994038_07600(pcp)
SPNO:	SPN994039_07610(pcp)
SSU:	SSU05_0794
SSV:	SSU98_0795
SSB:	SSUBM407_1093(pcp)
SSI:	SSU0740(pcp)
SSS:	SSUSC84_0705(pcp)
SST:	SSUST3_0930
SSF:	SSUA7_0737
SSK:	SSUD12_1004
SSQ:	SSUD9_0943
SSW:	SSGZ1_0778
SUI:	SSUJS14_0877
SUO:	SSU12_0739
SRP:	SSUST1_1041
SUP:	YYK_03540
SSUS:	NJAUSS_0837
SMB:	smi_0197(pcp)
STD:	SPPN_04365
LJO:	LJ1798
LJF:	FI9785_1747(pcp)
LJH:	LJP_1732c
LAC:	LBA0186
LAI:	LAC30SC_00885
LDB:	Ldb1175(pcp)
LBU:	LBUL_1093
LDE:	LDBND_1058(pcp)
LDL:	LBU_1004
LBR:	LVIS_1994
LBK:	LVISKB_1978
LCA:	LSEI_0206
LCB:	LCABL_01950(pcp)
LCZ:	LCAZH_0230
LCS:	LCBD_0195
LCE:	LC2W_0186
LCW:	BN194_01980(pcp)
LGA:	LGAS_1832
LHE:	lhv_0202
LHL:	LBHH_0191
LHR:	R0052_01060
LRH:	LGG_00238(pcp)
LRG:	LRHM_0233
LRL:	LC705_00228(pcp)
LRA:	LRHK_236(pcp) LRHK_2605(pcp)
LCR:	LCRIS_00186(pcp)
LAM:	LA2_01070
LAY:	LAB52_00965
LKE:	WANG_1811
LRM:	LRC_00160
EFA:	EF0401(pcp)
EFL:	EF62_0733(pcp)
EFI:	OG1RF_10287(pcp)
EFD:	EFD32_0334
EFS:	EFS1_0282(pcp)
EFC:	EFAU004_00642
EFU:	HMPREF0351_10666(pcp)
EFM:	M7W_830
EHR:	EHR_01280
ENE:	ENT_25870
ECAS:	ECBG_02402
MPS:	MPTP_1927
MPX:	MPD5_1723
THL:	TEH_05080(pcp)
CRN:	CAR_c14840(pcp)
CML:	BN424_3653(pcp)
CPE:	CPE1425
CPF:	CPF_1678(pcp)
CPR:	CPR_1413(pcp)
CBK:	CLL_A1534(pcp)
CBT:	CLH_1446(pcp)
CPY:	Cphy_2057
CSO:	CLS_16880
CDF:	CD630_16760(pcp)
CDC:	CD196_1598(pcp)
CDL:	CDR20291_1573(pcp)
CDG:	CDBI1_08260
CST:	CLOST_0120(pcp)
AOE:	Clos_2359
FMA:	FMG_0354
APR:	Apre_1235
RIX:	RO1_26180
RIM:	ROI_37620
CLO:	HMPREF0868_0102
BPRM:	CL3_04760
BPRS:	CK3_34780
TTE:	TTE0678(Pcp) TTE1612(Pcp2)
TEX:	Teth514_1374
THX:	Thet_1529
TPD:	Teth39_0955
TIT:	Thit_0947
TMT:	Tmath_1002
TBO:	Thebr_0982
TWI:	Thewi_1072
CPO:	COPRO5265_1354(pcp)
NTH:	Nther_2071
HPK:	Hprae_0380
VPR:	Vpar_0104
AFN:	Acfer_1956
AIN:	Acin_2260
ERH:	ERH_0382(pcp)
EUC:	EC1_07190
MTU:	Rv0319(pcp)
MTV:	RVBD_0319
MTC:	MT0334(pcp)
MRA:	MRA_0328(pcp)
MTF:	TBFG_10324
MTB:	TBMG_00323
MTK:	TBSG_00326
MTZ:	TBXG_000322
MTG:	MRGA327_02040
MTI:	MRGA423_02030
MTE:	CCDC5079_0297
MTL:	CCDC5180_0294
MTO:	MTCTRI2_0326(pcp)
MTD:	UDA_0319(pcp)
MTN:	ERDMAN_0354(pcp)
MTJ:	J112_01730
MTUB:	MT7199_0325(pcp)
MBO:	Mb0327(pcp)
MBB:	BCG_0359(pcp)
MBT:	JTY_0329(pcp)
MBM:	BCGMEX_0329(pcp)
MBK:	K60_003400
MAF:	MAF_03210(pcp)
MCE:	MCAN_03211(pcp)
MCQ:	BN44_10358(pcp)
MCV:	BN43_10353(pcp)
MCX:	BN42_20049(pcp)
MMI:	MMAR_0598(pcp)
MLI:	MULP_00591(pcp)
CRD:	CRES_0861
SCO:	SCO0438(pcp)
SVL:	Strvi_5729
SCT:	SCAT_0208(pcp)
SCY:	SCATT_02200
SBH:	SBI_02004
CMI:	CMM_0133
CMC:	CMN_00051
MTS:	MTES_0384
ART:	Arth_1486
AAU:	AAur_1621(pcp)
AAI:	AARI_00760(pcp)
ARR:	ARUE_c15310(pcp)
KRH:	KRH_07020(pcp)
MLU:	Mlut_14510
RMU:	RMDY18_05900
RDN:	HMPREF0733_10147(pcp)
BCV:	Bcav_2191
BFA:	Bfae_02130
JDE:	Jden_1230
IVA:	Isova_1475
SKE:	Sked_37410
CFI:	Celf_1850
PPC:	HMPREF9154_1660
SRO:	Sros_6277
FRE:	Franean1_3440
AMD:	AMED_8723(pcp)
AMN:	RAM_44760
AMM:	AMES_8593(pcp)
AMI:	Amir_0336
SESP:	BN6_03720(pcp)
AHE:	Arch_1014
BLO:	BL0323(pcp)
BLJ:	BLD_1081(pcp)
BLN:	Blon_0354 Blon_1066
BLON:	BLIJ_0361 BLIJ_1090
BLF:	BLIF_0269
BLL:	BLJ_0333 BLJ_1093
BLB:	BBMN68_1086(pcp)
BLM:	BLLJ_0289
BLK:	BLNIAS_02387
BLG:	BIL_15910
BAD:	BAD_0270(pcp)
BLA:	BLA_0318(pcp)
BLC:	Balac_0334
BLT:	Balat_0334
BBB:	BIF_00158
BBC:	BLC1_0320
BNM:	BALAC2494_00796
BLV:	BalV_0323
BLW:	W7Y_0336
BLS:	W91_0347
BNI:	BANAN_01730
BDE:	BDP_0378(pcp)
BBI:	BBIF_1377(pcp1) BBIF_1558(pcp)
BBP:	BBPR_1424 BBPR_1615(pcp)
BBF:	BBB_1408(pcp) BBB_1593(pcp)
BBV:	HMPREF9228_1769
BBRU:	Bbr_1702(pcp)
BAST:	BAST_1412
BTP:	D805_1501
GVA:	HMPREF0424_0563
GVG:	HMPREF0421_20338(pcp) HMPREF0421_21007(pcp2)
GVH:	HMPREF9231_1216
CWO:	Cwoe_5705
APV:	Apar_0340
OLS:	Olsu_1567
TDE:	TDE0175(pcp)
TPI:	TREPR_0937
SCC:	Spico_0458
BHY:	BHWA1_02432(pcp)
SBU:	SpiBuddy_2545
SGP:	SpiGrapes_0195
CTM:	Cabther_A1133
PAH:	Poras_1572
FNU:	FN1728
SMF:	Smon_0030
IPO:	Ilyop_0778
RBA:	RB3898(pcp)
PSL:	Psta_2223
TAI:	Taci_0439
SBR:	SY1_03950
SYP:	SYNPCC7002_A1439
MAR:	MAE_29950
CYP:	PCC8801_1503
CYC:	PCC7424_0181
CYN:	Cyan7425_1189
CYH:	Cyan8802_1530
CYJ:	Cyan7822_2303
GLP:	Glo7428_4301
GVI:	glr2409
ANA:	alr1369
NOS:	Nos7107_2204
NOP:	Nos7524_1300
AVA:	Ava_4016
ANB:	ANA_C10793
ACY:	Anacy_5334
NAZ:	Aazo_2144
CSG:	Cylst_1587
CALO:	Cal7507_4109
CALT:	Cal6303_4380
LEP:	Lepto7376_3615
OAC:	Oscil6304_3324
ONI:	Osc7112_4538
PSEU:	Pse7367_1611
CEP:	Cri9333_1058
MIC:	Mic7113_4736
CTHE:	Chro_2632
PLP:	Ple7327_2599
SCS:	Sta7437_2893
RRS:	RoseRS_1774
RCA:	Rcas_2052
ATM:	ANT_14950(pcp)
DRA:	DR_0490
DGE:	Dgeo_0441
DDR:	Deide_16250(pcp)
DMR:	Deima_2337
DGO:	DGo_CA0894(pcp)
DPD:	Deipe_0229
TTH:	TTC0531
TTJ:	TTHA0888
TTS:	Ththe16_0888
TTL:	TtJL18_1161
TSC:	TSC_c13250(pcp)
THC:	TCCBUS3UF1_11680
TOS:	Theos_1544
TLE:	Tlet_1256
TME:	Tmel_0762
TAF:	THA_1947
FNO:	Fnod_0998
FPE:	Ferpe_1124
KOL:	Kole_0819
MPZ:	Marpi_0049
MPG:	Theba_0092
NMG:	Nmag_1274
HJE:	HacjB3_02165
HBO:	Hbor_26710
NGE:	Natgr_2107
PHO:	PH0596
PAB:	PAB1419
PFU:	PF1299
PFI:	PFC_05710
PYN:	PNA2_1211
PYA:	PYCH_18870
PYS:	Py04_0964
TKO:	TK1835
TON:	TON_1690
TGA:	TGAM_0031(pcp)
TSI:	TSIB_1014
TBA:	TERMP_01917
THE:	GQS_06885
THA:	TAM4_1439
THM:	CL1_1007
ABI:	Aboo_1273
ACF:	AciM339_1265
SMR:	Smar_0684
SHC:	Shell_0106
DKA:	DKAM_1142
DFD:	Desfe_1254
HBU:	Hbut_1614
PFM:	Pyrfu_1389
SSO:	SSO1465(pcp) SSO1607(pcp-like)
SOL:	Ssol_2307
SAI:	Saci_1780(pcp)
SACN:	SacN8_08665
SACR:	SacRon12I_08675
SIS:	LS215_1148
SIA:	M1425_0496
SIM:	M1627_0511
SID:	M164_0533
SIY:	YG5714_0482
SIN:	YN1551_2531
SII:	LD85_0539
SIH:	SiH_0842
SIR:	SiRe_0507
SIC:	SiL_0531
TPE:	Tpen_1586
CLG:	Calag_0139
FFO:	FFONT_0877
HAH:	Halar_2028

» show all

Reference

Authors

Tsuru, D., Nakamura, K., Yoshimoto, T. and Fujiwara, K.

Title

Pyroglutamyl-peptidase from Bacillus amyloliquefaciens. An improved purification method and some properties of the enzyme.

Journal

Biochim. Biophys. Acta 791 (1984) 117-122.

Reference

2 [PMID:7824521]

Authors

Awade AC, Cleuziat P, Gonzales T, Robert-Baudouy J.

Title

Pyrrolidone carboxyl peptidase (Pcp): an enzyme that removes pyroglutamic acid (pGlu) from pGlu-peptides and pGlu-proteins.

Journal

Proteins. 20 (1994) 34-51.

Organism

Homo sapiens [GN:hsa]

Reference

3 [PMID:8529900]

Authors

Patti JM, Schneider A, Garza N, Boles JO.

Title

Isolation and characterization of pcp, a gene encoding a pyrrolidone carboxyl peptidase in Staphylococcus aureus.

Journal

Gene. 166 (1995) 95-9.

Organism

Staphylococcus aureus

Reference

4 [PMID:8655512]

Authors

Le Saux O, Gonzales T, Robert-Baudouy J.

Title

Mutational analysis of the active site of Pseudomonas fluorescens pyrrolidone carboxyl peptidase.

Journal

J. Bacteriol. 178 (1996) 3308-13.

Organism

Pseudomonas fluorescens

Other DBs

ExplorEnz - The Enzyme Database:

3.4.19.3

IUBMB Enzyme Nomenclature:

3.4.19.3

ExPASy - ENZYME nomenclature database:

3.4.19.3

BRENDA, the Enzyme Database:

3.4.19.3

CAS:

9075-21-2

All links

Ontology (2)   
   KEGG BRITE (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7651)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (790)   
   KEGG DGENES (15)   
   KEGG EGENES (324)   
   KEGG MGENES (6521)   
Protein sequence (3610)   
   UniProt (2038)   
   PRF (62)   
   RefSeq(pep) (1437)   
   PDBSTR (68)   
   PMD (5)   
DNA sequence (2456)   
   RefSeq(nuc) (1610)   
   GenBank (422)   
   EMBL (424)   
3D Structure (19)   
   PDB (19)   
Protein domain (3)   
   InterPro (2)   
   PROSITE(DOC) (1)   
Literature (3)   
   PubMed (3)   
Enzyme (4)   
   BRENDA (1)   
   EXPASY-ENZYME (1)   
   EXPLORENZ (1)   
   IUBMB (1)   
All databases (13750)   

Download RDF

DBGET integrated database retrieval system