KEGG   ENZYME: 3.6.3.15Help
Entry
EC 3.6.3.15                 Enzyme                                 

Name
Na+-transporting two-sector ATPase
Class
Hydrolases;
Acting on acid anhydrides;
Acting on acid anhydrides to catalyse transmembrane movement of substances
BRITE hierarchy
Sysname
ATP phosphohydrolase (Na+-transporting)
Reaction(IUBMB)
ATP + H2O + Na+in = ADP + phosphate + Na+out [RN:R00086]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001];
Na+ [CPD:C01330]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
Na+ [CPD:C01330]
Comment
A multisubunit non-phosphorylated ATPase that is involved in the transport of ions. An enzyme found in alkaliphilic bacteria that is similar to EC 3.6.3.14 (H+-transporting two-sector ATPase) where Na+ replaces H+.
History
EC 3.6.3.15 created 2000
Orthology
K01550  
Na+-transporting two-sector ATPase
Reference
1  [PMID:8144530]
  Authors
Solioz M, Davies K.
  Title
Operon of vacuolar-type Na(+)-ATPase of Enterococcus hirae.
  Journal
J. Biol. Chem. 269 (1994) 9453-9.
  Organism
Enterococcus hirae
  Sequence
[ehr:EHR_08260]
Reference
2  [PMID:8157629]
  Authors
Takase K, Kakinuma S, Yamato I, Konishi K, Igarashi K, Kakinuma Y.
  Title
Sequencing and characterization of the ntp gene cluster for vacuolar-type Na(+)-translocating ATPase of Enterococcus hirae.
  Journal
J. Biol. Chem. 269 (1994) 11037-44.
  Organism
Enterococcus hirae
Reference
3  [PMID:9119076]
  Authors
Rahlfs S, Muller V.
  Title
Sequence of subunit c of the Na(+)-translocating F1F0 ATPase of Acetobacterium woodii: proposal for determinants of Na+ specificity as revealed by sequence comparisons.
  Journal
FEBS. Lett. 404 (1997) 269-71.
  Organism
Acetobacterium woodii
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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