peptide-transporting ATPase

Hydrolases;
Acting on acid anhydrides;
Acting on acid anhydrides to catalyse transmembrane movement of substances

ATP phosphohydrolase (peptide-exporting)

ATP + H2O + peptidein = ADP + phosphate + peptideout [RN:R00086]

R00086

ATP [CPD:C00002];
H2O [CPD:C00001];
peptide [CPD:C00012]

ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. A family of enzymes that exports alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria.

1  [PMID:8085823]

Klein C, Entian KD.

Genes involved in self-protection against the lantibiotic subtilin produced by Bacillus subtilis ATCC 6633.

Appl. Environ. Microbiol. 60 (1994) 2793-801.

Bacillus subtilis [GN:bsu]

2  [PMID:8107849]

Momburg F, Roelse J, Howard JC, Butcher GW, Hammerling GJ, Neefjes JJ.

Selectivity of MHC-encoded peptide transporters from human, mouse and rat.

Nature. 367 (1994) 648-51.

human [GN:hsa], Mus musculus [GN:mmu], Rattus norvegicus [GN:rno]

3  [PMID:9224868]

Binet R, Letoffe S, Ghigo JM, Delepelaire P, Wandersman C.

Protein secretion by Gram-negative bacterial ABC exporters--a review.

Gene. 192 (1997) 7-11.

Erwinia chrysanthemi