| Entry |
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| Name |
glucose 1-dehydrogenase (FAD, quinone);
glucose dehydrogenase (Aspergillus);
FAD-dependent glucose dehydrogenase;
D-glucose:(acceptor) 1-oxidoreductase;
glucose dehydrogenase (acceptor);
gdh (gene name)
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| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With a quinone or similar compound as acceptor
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| Sysname |
D-glucose:quinone 1-oxidoreductase
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| Reaction(IUBMB) |
D-glucose + a quinone = D-glucono-1,5-lactone + a quinol [RN: R00305]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
A glycoprotein containing one mole of FAD per mole of enzyme. 2,6-Dichloroindophenol can act as acceptor. cf. EC 1.1.5.2, quinoprotein glucose dehydrogenase.
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| History |
EC 1.1.5.9 created 1972 as 1.1.99.10, modified 1976, transferred 2013 to EC 1.1.5.9
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| Pathway |
| Pentose phosphate pathway | | Metabolic pathways | | Biosynthesis of secondary metabolites | | Biosynthesis of antibiotics |
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| Orthology |
| glucose 1-dehydrogenase (FAD, quinone) | | glucose dehydrogenase |
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| Genes |
DME: | | DPO: | | DAN: | | DER: | | DPE: | | DSE: | | DSI: | | DWI: | | DYA: | | DGR: | | DMO: | | DVI: | | MDE: | | AGA: | | AAG: | | CQU: | | AME: | | BIM: | | BTER: | | SOC: | | AEC: | | ACEP: | | PBAR: | | HST: | | CFO: | | LHU: | | NVI: | | TCA: | | DPA: | | NVL: | | BMOR: | | PXY: | | API: | | DNX: | | PHU: | | YEN: | | YEP: | | YEY: | | YEW: | | YET: | | YEF: | | YEE: | | YAL: | | YFR: | | YKR: | | YAK: | | PAO: | | TCI: | | PCQ: | | PDR: | | PKC: | | ACX: | | MAGA: | | CMAI: | | RSL: | | RSM: | | RSE: | | RPF: | | RMN: | | RIN: | | BMA: | | BMV: | | BML: | | BMN: | | BMAL: | | BMAE: | | BMAQ: | | BMAI: | | BMAF: | | BMAZ: | | BMAB: | | BPS: | | BPM: | | BPL: | | BPD: | | BPSE: | | BPSM: | | BPSU: | | BPSD: | | BPZ: | | BPQ: | | BPK: | | BPSH: | | BPSA: | | BPSO: | | BUT: | | BTE: | | BTQ: | | BTJ: | | BTZ: | | BTD: | | BTV: | | BTHE: | | BTHM: | | BTHA: | | BTHL: | | BOK: | | BOC: | | BVI: | | BVE: | | BUR: | | BCN: | | BCH: | | BCM: | | BCJ: | | BCEN: | | BCEW: | | BCEO: | | BAM: | | BAC: | | BMU: | | BMK: | | BMUL: | | BCT: | | BCED: | | BCEP: | | BDL: | | BPYR: | | BCON: | | BUB: | | BDF: | | BLAT: | | BTEI: | | BSEM: | | BPSL: | | BMEC: | | BSTG: | | BUK: | | BUL: | | BUD: | | BFN: | | BCAI: | | PSPW: | | JAZ: | | CFU: | | CARE: | | CPRA: | | HOE: | | RLU: | | NGG: | | MSC: | | MALG: | | HAT: | | YAN: | | TOM: | | ZMM: | | ZMB: | | ZMI: | | ZMC: | | ZMR: | | ZMP: | | GOH: | | GOY: | | GAL: | | GXY: | | GXL: | | KNA: | | KEU: | | APW: | | APF: | | APU: | | APG: | | APQ: | | APX: | | APZ: | | APK: | | ASZ: | | ASV: | | APER: | | KBA: | | GPH: | |
» show all
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| Reference |
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| Authors |
Bak TG. |
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| Title |
Studies on glucose dehydrogenase of Aspergillus oryzae. II. Purification and physical and chemical properties. |
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| Journal |
Biochim. Biophys. Acta. 139 (1967) 277-93. |
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| Reference |
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| Authors |
Cavener DR, MacIntyre RJ |
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| Title |
Biphasic expression and function of glucose dehydrogenase in Drosophila melanogaster. |
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| Journal |
Proc. Natl. Acad. Sci. U. S. A. 80 (1983) 6286-8. |
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| Reference |
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| Authors |
Lovallo N, Cox-Foster DL |
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| Title |
Alteration in FAD-glucose dehydrogenase activity and hemocyte behavior contribute to initial disruption of Manduca sexta immune response to Cotesia congregata parasitoids. |
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| Journal |
J. Insect. Physiol. 45 (1999) 1037-1048. |
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| Reference |
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| Authors |
Inose K, Fujikawa M, Yamazaki T, Kojima K, Sode K |
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| Title |
Cloning and expression of the gene encoding catalytic subunit of thermostable glucose dehydrogenase from Burkholderia cepacia in Escherichia coli. |
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| Journal |
Biochim. Biophys. Acta. 1645 (2003) 133-8. |
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| Sequence |
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| Reference |
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| Authors |
Sygmund C, Klausberger M, Felice AK, Ludwig R |
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| Title |
Reduction of quinones and phenoxy radicals by extracellular glucose dehydrogenase from Glomerella cingulata suggests a role in plant pathogenicity. |
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| Journal |
Microbiology. 157 (2011) 3203-12. |
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| Reference |
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| Authors |
Sygmund C, Staudigl P, Klausberger M, Pinotsis N, Djinovic-Carugo K, Gorton L, Haltrich D, Ludwig R |
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| Title |
Heterologous overexpression of Glomerella cingulata FAD-dependent glucose dehydrogenase in Escherichia coli and Pichia pastoris. |
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| Journal |
Microb. Cell. Fact. 10 (2011) 106. |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 37250-84-3 |
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