KEGG ORTHOLOGY: K00150

ORTHOLOGY: K00150

Entry

K00150 KO

Name

gap2

Definition

glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) [EC:1.2.1.59]

Pathway

ko00010	Glycolysis / Gluconeogenesis
ko00710	Carbon fixation in photosynthetic organisms
ko01200	Carbon metabolism
ko01230	Biosynthesis of amino acids

Module

M00001	Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
M00002	Glycolysis, core module involving three-carbon compounds
M00003	Gluconeogenesis, oxaloacetate => fructose-6P
M00165	Reductive pentose phosphate cycle (Calvin cycle)
M00166	Reductive pentose phosphate cycle, ribulose-5P => glyceraldehyde-3P

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Overview
   01200 Carbon metabolism
    K00150  gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P))
   01230 Biosynthesis of amino acids
    K00150  gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P))
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    K00150  gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P))
  Energy metabolism
   00710 Carbon fixation in photosynthetic organisms
    K00150  gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P))
KEGG modules [BR:ko00002]
Pathway module
  Energy metabolism
   Carbon fixation
    M00165  Reductive pentose phosphate cycle (Calvin cycle)
     K00150  gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P))
    M00166  Reductive pentose phosphate cycle, ribulose-5P => glyceraldehyde-3P
     K00150  gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P))
  Carbohydrate and lipid metabolism
   Central carbohydrate metabolism
    M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
     K00150  gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P))
    M00002  Glycolysis, core module involving three-carbon compounds
     K00150  gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P))
    M00003  Gluconeogenesis, oxaloacetate => fructose-6P
     K00150  gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P))
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.59  glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)
     K00150  gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P))

Other DBs

RN:

R01061 R01063

COG:

COG0057

GO:

0043891

Genes

PAEU:	BN889_06934
MARI:	ACP86_11820
MLQ:	ASQ50_01600
HAM:	HALO1614
GBI:	PG2T_06825
AJS:	Ajs_2165 Ajs_2680
ACK:	C380_06000
ACID:	CBP33_07180
ADK:	Alide2_2718
HYB:	Q5W_09960
NII:	Nit79A3_0299
DTI:	Desti_2694
MESO:	BSQ44_04110
MES:	Meso_3884
HOE:	IMCC20628_04816
CHEL:	AL346_10520
RBM:	TEF_02830
PZU:	PHZ_p0131
RMM:	ROSMUCSMR3_04172
NPP:	PP1Y_AT23129
NPN:	JI59_04860
ERY:	CP97_05610
AAY:	WYH_02517
CNA:	AB433_14790
CMAN:	A9D14_19235
CLO:	HMPREF0868_0016
CMQ:	B840_12970(gapB2)
SGS:	AVL59_12505
KFV:	AS188_15125
MLU:	Mlut_18410
SYN:	sll1342(gap2)
SYZ:	MYO_129570(gap2)
SYY:	SYNGTS_2929(gap2)
SYT:	SYNGTI_2928(gap2)
SYS:	SYNPCCN_2927(gap2)
SYQ:	SYNPCCP_2927(gap2)
SYJ:	D082_08170(gap2)
SYW:	SYNW0030(gap2)
SYC:	syc2349_c(gap2)
SYF:	Synpcc7942_1742
SYD:	Syncc9605_0030
SYE:	Syncc9902_0026
SYG:	sync_0029(gap-1)
SYR:	SynRCC307_0028(gap1)
SYX:	SynWH7803_0029(gap1)
SYP:	SYNPCC7002_A0106(gap)
CYA:	CYA_0325(gap-2)
CYB:	CYB_1704(gap-2)
SYNE:	Syn6312_3152
SYNP:	Syn7502_02294
SYNK:	KR100_00955(gapA)
SYNR:	KR49_09050(gapA)
SYND:	KR52_02330(gapA)
SYU:	M744_07770
SYH:	Syncc8109_0030(gap2)
SYNW:	SynWH8103_00029(gap2)
TEL:	tll1466
THN:	NK55_02785(gap2)
CGC:	Cyagr_2332
CYI:	CBM981_2391(gap)
DSL:	Dacsa_1284
CMP:	Cha6605_3592
LEP:	Lepto7376_0133
LEN:	LEP3755_20840
LET:	O77CONTIG1_02614(gap2)
LBO:	LBWT_1060
HHG:	XM38_038250(gap2)
PSEU:	Pse7367_0081
PMA:	Pro_0023(gap2)
PMM:	PMM0023(gap2)
PMT:	PMT_0028
PMN:	PMN2A_1350
PMI:	PMT9312_0023
PMB:	A9601_00221(gap2)
PMC:	P9515_00221(gap2)
PMF:	P9303_00271(gap2)
PMG:	P9301_00221(gap2)
PMH:	P9215_00221(gap2)
PMJ:	P9211_00231(gap2)
PME:	NATL1_00221(gap2)
PRC:	EW14_0023
PRM:	EW15_0024
AMR:	AM1_4369(gapA)
MAR:	MAE_25030
MPK:	VL20_4417
CAN:	Cyan10605_3072
CSN:	Cyast_1687
HAO:	PCC7418_0720
GLP:	Glo7428_3592
GEN:	GM3709_2641
GEE:	GM3708_2476
CYP:	PCC8801_2557
CYC:	PCC7424_2221
CYN:	Cyan7425_0946
CYH:	Cyan8802_3549
CYJ:	Cyan7822_4638
TER:	Tery_4030
MIC:	Mic7113_2091
ARP:	NIES39_C00270(gap)
GEI:	GEI7407_2652
OAC:	Oscil6304_0603
ONI:	Osc7112_4898
MPRO:	BJP34_06935
CEP:	Cri9333_2336
GVI:	gvip056(gap1)
GLJ:	GKIL_1218(gap2)
ANA:	all5062(gap2)
NPU:	Npun_R0444
NOS:	Nos7107_2266
NOP:	Nos7524_5283
NON:	NOS3756_28700
AVA:	Ava_2318
ANB:	ANA_C12497
ACY:	Anacy_0265
AWA:	AA650_19390
NAZ:	Aazo_0813
CSG:	Cylst_5376
CALO:	Cal7507_0037
CALT:	Cal6303_4016
CALH:	IJ00_23650
RIV:	Riv7116_0750
FIS:	FIS3754_36610
NCN:	BZZ01_26190
CTHE:	Chro_4726
PLP:	Ple7327_4413
SCS:	Sta7437_0238
DLY:	Dehly_0804
DFO:	Dform_01359(gap2)
ABAO:	BEQ56_08940
TPI:	TREPR_0394
SSM:	Spirs_0990
SCC:	Spico_0086
SGP:	SpiGrapes_3134
CMR:	Cycma_4563 Cycma_4565
EVI:	Echvi_3157
MTT:	Ftrac_2076
GFL:	GRFL_3040
ZPR:	ZPR_3400
LUL:	LPB138_11440
SALT:	AO058_13725
KOL:	Kole_0996
KPF:	IX53_05910
MJA:	MJ_1146
MFE:	Mefer_0809
MVU:	Metvu_0390
MFS:	MFS40622_0779
MIF:	Metin_0953
MJH:	JH146_0701
MIG:	Metig_1019
MMP:	MMP0325
MMQ:	MmarC5_1348
MMX:	MmarC6_0626
MMZ:	MmarC7_1327
MMD:	GYY_01675
MMAK:	MMKA1_03330(gap)
MMAO:	MMOS7_03600(gap)
MAE:	Maeo_0627
MVN:	Mevan_1336
MVO:	Mvol_1211
MOK:	Metok_0880
MAC:	MA_1018(gap) MA_3345(gap)
MBA:	Mbar_A2189 Mbar_A3564
MBY:	MSBRM_1921 MSBRM_2242
MBW:	MSBRW_1171 MSBRW_2552
MBAR:	MSBR2_0167 MSBR2_0489
MBAK:	MSBR3_1050 MSBR3_1146
MMA:	MM_2782
MMAZ:	MmTuc01_2831
MMJ:	MSMAS_1945
MMAC:	MSMAC_1180
MVC:	MSVAZ_2027
MEK:	MSKOL_2005
MLS:	MSLAZ_1558
METM:	MSMTP_1360
MEF:	MSWH1_1524
MEQ:	MSWHS_1783
MSJ:	MSSAC_2557 MSSAC_3452
MSZ:	MSSIH_2160 MSSIH_2980
MSW:	MSSIT_2267 MSSIT_3037
MTHE:	MSTHC_0292
MTHR:	MSTHT_0429
MHOR:	MSHOH_1621 MSHOH_2523
MBU:	Mbur_0851
MMET:	MCMEM_0983
MMH:	Mmah_1159
MHAZ:	BHR79_07740
MEV:	Metev_0436
MZH:	Mzhil_1145
MPY:	Mpsy_2902
MHZ:	Metho_0889
MTP:	Mthe_0701
MCJ:	MCON_2908
MHI:	Mhar_1240
MHU:	Mhun_2462
MLA:	Mlab_1723
MEM:	Memar_2497
MBG:	BN140_2174(gapA) BN140_2612(gap)
MEMA:	MMAB1_3505(gap)
MPI:	Mpet_2779
MBN:	Mboo_1283 Mboo_2454
MFO:	Metfor_0186
MPL:	Mpal_2790
MPD:	MCP_1270(gap-1) MCP_2688(gap-2)
MEZ:	Mtc_0299(gap)
RCI:	RCIX551(gap)
MTH:	MTH_1009
MMG:	MTBMA_c13910(gap)
METC:	MTCT_0917
MWO:	MWSIV6_1395(gap)
MST:	Msp_1346(gap)
MSI:	Msm_0962
MRU:	mru_1856(gap)
MEB:	Abm4_1478(gap)
MMIL:	sm9_1923(gap)
MEYE:	TL18_09080
MOL:	YLM1_1311
MEL:	Metbo_1751 Metbo_2379
MEW:	MSWAN_0266
METH:	MBMB1_0326(gap)
MFC:	BRM9_1942(gap)
MFI:	DSM1535_0130(gap)
MCUB:	MCBB_0298(gap)
MFV:	Mfer_0276
MKA:	MK0618(gapA)
AFU:	AF_1732
AFG:	AFULGI_00019830
APO:	Arcpr_0732
AVE:	Arcve_0098
AST:	Asulf_01633
FPL:	Ferp_1302
GAC:	GACE_0477
GAH:	GAH_01734
HAL:	VNG_0095G(gapB) VNG_1297C
HSL:	OE_1154F(gap)
HDL:	HALDL1_03425
HHB:	Hhub_1290(gap)
HJE:	HacjB3_14555
HALH:	HTSR_0246(gapB)
HHSR:	HSR6_0233(gapB)
HMA:	rrnAC2262(gapB)
HHI:	HAH_2730(gapA1)
HHN:	HISP_13880
HAB:	SG26_06160
NPH:	NP_0012A(gap)
NMO:	Nmlp_1502(gap)
HMU:	Hmuk_0529
HALI:	BV210_06795
HSU:	HLASF_0350(gapB)
HSF:	HLASA_0349(gapB)
HWA:	HQ_1360A(gap1) HQ_2025A(gap3)
HWC:	Hqrw_1421(gap1)
HVO:	HVO_0478
HME:	HFX_0444(gapA)
HGI:	ABY42_02215
HBO:	Hbor_26990
HLA:	Hlac_1672
HTU:	Htur_0284
HDA:	BB347_12400
NMG:	Nmag_2141
HXA:	Halxa_1641
NAT:	NJ7G_0220
NPE:	Natpe_3640
NGE:	Natgr_1664
HRU:	Halru_0450
NOU:	Natoc_0189
SALI:	L593_02145
HLR:	HALLA_06130
HLC:	CHINAEXTREME03235
TAC:	Ta1103
TVO:	TVG0444310(TVG0444310)
PTO:	PTO0742
FAC:	FACI_IFERC01G1571
FAI:	FAD_0549
CDIV:	CPM_0301
TAR:	TALC_01406
MAX:	MMALV_15110
MER:	MMINT_02260
MEAR:	Mpt1_c00900(gap)
MARC:	AR505_0154
PHO:	PH1830(PH1830)
PAB:	PAB0257(gap)
PFU:	PF1874
PFI:	PFC_09215
PYN:	PNA2_0429
PYA:	PYCH_00860
PYS:	Py04_1761
PYC:	TQ32_07585
TKO:	TK0765
TON:	TON_0639
TGA:	TGAM_1667(gap)
TSI:	TSIB_0949
TBA:	TERMP_00454
THE:	GQS_01790
THA:	TAM4_1537
THM:	CL1_0086
TLT:	OCC_07249
THS:	TES1_0542
TNU:	BD01_0756
TEU:	TEU_08915
TGY:	X802_01260
THV:	ADU37_CDS06300
TCH:	CHITON_2116
TPEP:	A0127_01245
PPAC:	PAP_02855
ABI:	Aboo_0431
ACF:	AciM339_0618
APE:	APE_0171.1
ACJ:	ACAM_0134
SMR:	Smar_0241
SHC:	Shell_0576
IHO:	Igni_1001
IIS:	EYM_03900
DKA:	DKAM_0185
DFD:	Desfe_0262
DMU:	Desmu_0845
TAG:	Tagg_0301
THG:	TCELL_1375
HBU:	Hbut_0939
PFM:	Pyrfu_1285
PDL:	Pyrde_1673
SSO:	SSO0528(gap)
SOL:	Ssol_1613
SSOA:	SULA_1640
SSOL:	SULB_1641
SSOF:	SULC_1639
STO:	STK_13560(gap)
SAI:	Saci_1356
SACN:	SacN8_06615
SACR:	SacRon12I_06605
SACS:	SUSAZ_06485
SIS:	LS215_1689
SIA:	M1425_1581
SIM:	M1627_1697
SID:	M164_1578
SIY:	YG5714_1585
SIN:	YN1551_1251
SII:	LD85_1789
SIH:	SiH_1548
SIR:	SiRe_1456
SIC:	SiL_1458
SULA:	BFU36_04430
MSE:	Msed_1652
MCN:	Mcup_0577
AHO:	Ahos_1308
AMAN:	B6F84_10980
PAI:	PAE1740
PIS:	Pisl_1710
PCL:	Pcal_0632
PAS:	Pars_0743
PYR:	P186_0070
POG:	Pogu_1600
TNE:	Tneu_0730
PYW:	PYWP30_00779
CMA:	Cmaq_1790
TUZ:	TUZN_2003
TTN:	TTX_1534(gap)
VDI:	Vdis_1977
VMO:	VMUT_0389
TPE:	Tpen_0757 Tpen_1765
ASC:	ASAC_0892
CLG:	Calag_0739
FFO:	FFONT_0242
NMR:	Nmar_0831
NID:	NPIRD3C_1371
NIN:	NADRNF5_1235
NKR:	NKOR_04585
NCT:	NMSP_0789(gap)
CSY:	CENSYa_0972
NGA:	Ngar_c16720(gap)
NVN:	NVIE_005380(gap)
NEV:	NTE_01905
TAA:	NMY3_03314
CSU:	CSUB_C1460
NBV:	T478_0731
TAH:	SU86_001980
NDV:	NDEV_1047(gap)
NAC:	AQV86_01560
KCR:	Kcr_0230
BARC:	AOA65_1541(gap)
HAH:	Halar_3698

» show all

Reference

PMID:9226260

Authors

Valverde F, Losada M, Serrano A

Title

Functional complementation of an Escherichia coli gap mutant supports an amphibolic role for NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase of Synechocystis sp. strain PCC 6803.

Journal

J Bacteriol 179:4513-22 (1997)
DOI:10.1128/JB.179.14.4513-4522.1997

Sequence

[syn:sll1342]

Reference

PMID:9484473

Authors

Koksharova O, Schubert M, Shestakov S, Cerff R

Title

Genetic and biochemical evidence for distinct key functions of two highly divergent GAPDH genes in catabolic and anabolic carbon flow of the cyanobacterium Synechocystis sp. PCC 6803.

Journal

Plant Mol Biol 36:183-94 (1998)
DOI:10.1023/A:1005925732743

All links

Ontology (5)   
   KEGG BRITE (3)   
   GO (1)   
   COG (1)   
Pathway (21)   
   KEGG PATHWAY (16)   
   KEGG MODULE (5)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
   KEGG RCLASS (1)   
Gene (12470)   
   KEGG GENES (399)   
   KEGG MGENES (9511)   
   RefGene (2532)   
   EGENES (9)   
   OC (19)   
Protein sequence (412)   
   UniProt (357)   
   SWISS-PROT (55)   
Literature (2)   
   PubMed (2)   
All databases (12914)   

Download RDF

ENZYME: 1.2.1.59

Entry

EC 1.2.1.59 Enzyme

Name

glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating);
triosephosphate dehydrogenase (NAD(P));
glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating)

Class

Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor

Sysname

D-glyceraldehyde 3-phosphate:NAD(P)+ oxidoreductase (phosphorylating)

Reaction(IUBMB)

D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+ [RN:R01061 R01063]

Reaction(KEGG)

R01061 R01063

Substrate

D-glyceraldehyde 3-phosphate [CPD:C00118];
phosphate [CPD:C00009];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]

Product

3-phospho-D-glyceroyl phosphate [CPD:C00236];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]

Comment

NAD+ and NADP+ can be used as cofactors with similar efficiency, unlike EC 1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) and EC 1.2.1.13 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating), which are NAD+- and NADP+-dependent, respectively.

History

EC 1.2.1.59 created 1999

Pathway

ec00010	Glycolysis / Gluconeogenesis
ec00710	Carbon fixation in photosynthetic organisms
ec01100	Metabolic pathways
ec01110	Biosynthesis of secondary metabolites
ec01120	Microbial metabolism in diverse environments
ec01130	Biosynthesis of antibiotics

Orthology

K00150

glyceraldehyde-3-phosphate dehydrogenase (NAD(P))

Genes

PAEU:	BN889_06934
MARI:	ACP86_11820
MLQ:	ASQ50_01600
HAM:	HALO1614
GBI:	PG2T_06825
AJS:	Ajs_2165 Ajs_2680
ACK:	C380_06000
ACID:	CBP33_07180
ADK:	Alide2_2718
HYB:	Q5W_09960
NII:	Nit79A3_0299
DTI:	Desti_2694
MESO:	BSQ44_04110
MES:	Meso_3884
HOE:	IMCC20628_04816
CHEL:	AL346_10520
RBM:	TEF_02830
PZU:	PHZ_p0131
RMM:	ROSMUCSMR3_04172
NPP:	PP1Y_AT23129
NPN:	JI59_04860
ERY:	CP97_05610
AAY:	WYH_02517
CNA:	AB433_14790
CMAN:	A9D14_19235
CLO:	HMPREF0868_0016
CMQ:	B840_12970(gapB2)
SGS:	AVL59_12505
KFV:	AS188_15125
MLU:	Mlut_18410
SYN:	sll1342(gap2)
SYZ:	MYO_129570(gap2)
SYY:	SYNGTS_2929(gap2)
SYT:	SYNGTI_2928(gap2)
SYS:	SYNPCCN_2927(gap2)
SYQ:	SYNPCCP_2927(gap2)
SYJ:	D082_08170(gap2)
SYW:	SYNW0030(gap2)
SYC:	syc2349_c(gap2)
SYF:	Synpcc7942_1742
SYD:	Syncc9605_0030
SYE:	Syncc9902_0026
SYG:	sync_0029(gap-1)
SYR:	SynRCC307_0028(gap1)
SYX:	SynWH7803_0029(gap1)
SYP:	SYNPCC7002_A0106(gap)
CYA:	CYA_0325(gap-2)
CYB:	CYB_1704(gap-2)
SYNE:	Syn6312_3152
SYNP:	Syn7502_02294
SYNK:	KR100_00955(gapA)
SYNR:	KR49_09050(gapA)
SYND:	KR52_02330(gapA)
SYU:	M744_07770
SYH:	Syncc8109_0030(gap2)
SYNW:	SynWH8103_00029(gap2)
TEL:	tll1466
THN:	NK55_02785(gap2)
CGC:	Cyagr_2332
CYI:	CBM981_2391(gap)
DSL:	Dacsa_1284
CMP:	Cha6605_3592
LEP:	Lepto7376_0133
LEN:	LEP3755_20840
LET:	O77CONTIG1_02614(gap2)
LBO:	LBWT_1060
HHG:	XM38_038250(gap2)
PSEU:	Pse7367_0081
PMA:	Pro_0023(gap2)
PMM:	PMM0023(gap2)
PMT:	PMT_0028
PMN:	PMN2A_1350
PMI:	PMT9312_0023
PMB:	A9601_00221(gap2)
PMC:	P9515_00221(gap2)
PMF:	P9303_00271(gap2)
PMG:	P9301_00221(gap2)
PMH:	P9215_00221(gap2)
PMJ:	P9211_00231(gap2)
PME:	NATL1_00221(gap2)
PRC:	EW14_0023
PRM:	EW15_0024
AMR:	AM1_4369(gapA)
MAR:	MAE_25030
MPK:	VL20_4417
CAN:	Cyan10605_3072
CSN:	Cyast_1687
HAO:	PCC7418_0720
GLP:	Glo7428_3592
GEN:	GM3709_2641
GEE:	GM3708_2476
CYP:	PCC8801_2557
CYC:	PCC7424_2221
CYN:	Cyan7425_0946
CYH:	Cyan8802_3549
CYJ:	Cyan7822_4638
TER:	Tery_4030
MIC:	Mic7113_2091
ARP:	NIES39_C00270(gap)
GEI:	GEI7407_2652
OAC:	Oscil6304_0603
ONI:	Osc7112_4898
MPRO:	BJP34_06935
CEP:	Cri9333_2336
GVI:	gvip056(gap1)
GLJ:	GKIL_1218(gap2)
ANA:	all5062(gap2)
NPU:	Npun_R0444
NOS:	Nos7107_2266
NOP:	Nos7524_5283
NON:	NOS3756_28700
AVA:	Ava_2318
ANB:	ANA_C12497
ACY:	Anacy_0265
AWA:	AA650_19390
NAZ:	Aazo_0813
CSG:	Cylst_5376
CALO:	Cal7507_0037
CALT:	Cal6303_4016
CALH:	IJ00_23650
RIV:	Riv7116_0750
FIS:	FIS3754_36610
NCN:	BZZ01_26190
CTHE:	Chro_4726
PLP:	Ple7327_4413
SCS:	Sta7437_0238
DLY:	Dehly_0804
DFO:	Dform_01359(gap2)
ABAO:	BEQ56_08940
TPI:	TREPR_0394
SSM:	Spirs_0990
SCC:	Spico_0086
SGP:	SpiGrapes_3134
CMR:	Cycma_4563 Cycma_4565
EVI:	Echvi_3157
MTT:	Ftrac_2076
GFL:	GRFL_3040
ZPR:	ZPR_3400
LUL:	LPB138_11440
SALT:	AO058_13725
KOL:	Kole_0996
KPF:	IX53_05910
MJA:	MJ_1146
MFE:	Mefer_0809
MVU:	Metvu_0390
MFS:	MFS40622_0779
MIF:	Metin_0953
MJH:	JH146_0701
MIG:	Metig_1019
MMP:	MMP0325
MMQ:	MmarC5_1348
MMX:	MmarC6_0626
MMZ:	MmarC7_1327
MMD:	GYY_01675
MMAK:	MMKA1_03330(gap)
MMAO:	MMOS7_03600(gap)
MAE:	Maeo_0627
MVN:	Mevan_1336
MVO:	Mvol_1211
MOK:	Metok_0880
MAC:	MA_1018(gap) MA_3345(gap)
MBA:	Mbar_A2189 Mbar_A3564
MBY:	MSBRM_1921 MSBRM_2242
MBW:	MSBRW_1171 MSBRW_2552
MBAR:	MSBR2_0167 MSBR2_0489
MBAK:	MSBR3_1050 MSBR3_1146
MMA:	MM_2782
MMAZ:	MmTuc01_2831
MMJ:	MSMAS_1945
MMAC:	MSMAC_1180
MVC:	MSVAZ_2027
MEK:	MSKOL_2005
MLS:	MSLAZ_1558
METM:	MSMTP_1360
MEF:	MSWH1_1524
MEQ:	MSWHS_1783
MSJ:	MSSAC_2557 MSSAC_3452
MSZ:	MSSIH_2160 MSSIH_2980
MSW:	MSSIT_2267 MSSIT_3037
MTHE:	MSTHC_0292
MTHR:	MSTHT_0429
MHOR:	MSHOH_1621 MSHOH_2523
MBU:	Mbur_0851
MMET:	MCMEM_0983
MMH:	Mmah_1159
MHAZ:	BHR79_07740
MEV:	Metev_0436
MZH:	Mzhil_1145
MPY:	Mpsy_2902
MHZ:	Metho_0889
MTP:	Mthe_0701
MCJ:	MCON_2908
MHI:	Mhar_1240
MHU:	Mhun_2462
MLA:	Mlab_1723
MEM:	Memar_2497
MBG:	BN140_2174(gapA) BN140_2612(gap)
MEMA:	MMAB1_3505(gap)
MPI:	Mpet_2779
MBN:	Mboo_1283 Mboo_2454
MFO:	Metfor_0186
MPL:	Mpal_2790
MPD:	MCP_1270(gap-1) MCP_2688(gap-2)
MEZ:	Mtc_0299(gap)
RCI:	RCIX551(gap)
MTH:	MTH_1009
MMG:	MTBMA_c13910(gap)
METC:	MTCT_0917
MWO:	MWSIV6_1395(gap)
MST:	Msp_1346(gap)
MSI:	Msm_0962
MRU:	mru_1856(gap)
MEB:	Abm4_1478(gap)
MMIL:	sm9_1923(gap)
MEYE:	TL18_09080
MOL:	YLM1_1311
MEL:	Metbo_1751 Metbo_2379
MEW:	MSWAN_0266
METH:	MBMB1_0326(gap)
MFC:	BRM9_1942(gap)
MFI:	DSM1535_0130(gap)
MCUB:	MCBB_0298(gap)
MFV:	Mfer_0276
MKA:	MK0618(gapA)
AFU:	AF_1732
AFG:	AFULGI_00019830
APO:	Arcpr_0732
AVE:	Arcve_0098
AST:	Asulf_01633
FPL:	Ferp_1302
GAC:	GACE_0477
GAH:	GAH_01734
HAL:	VNG_0095G(gapB) VNG_1297C
HSL:	OE_1154F(gap)
HDL:	HALDL1_03425
HHB:	Hhub_1290(gap)
HJE:	HacjB3_14555
HALH:	HTSR_0246(gapB)
HHSR:	HSR6_0233(gapB)
HMA:	rrnAC2262(gapB)
HHI:	HAH_2730(gapA1)
HHN:	HISP_13880
HAB:	SG26_06160
NPH:	NP_0012A(gap)
NMO:	Nmlp_1502(gap)
HMU:	Hmuk_0529
HALI:	BV210_06795
HSU:	HLASF_0350(gapB)
HSF:	HLASA_0349(gapB)
HWA:	HQ_1360A(gap1) HQ_2025A(gap3)
HWC:	Hqrw_1421(gap1)
HVO:	HVO_0478
HME:	HFX_0444(gapA)
HGI:	ABY42_02215
HBO:	Hbor_26990
HLA:	Hlac_1672
HTU:	Htur_0284
HDA:	BB347_12400
NMG:	Nmag_2141
HXA:	Halxa_1641
NAT:	NJ7G_0220
NPE:	Natpe_3640
NGE:	Natgr_1664
HRU:	Halru_0450
NOU:	Natoc_0189
SALI:	L593_02145
HLR:	HALLA_06130
HLC:	CHINAEXTREME03235
TAC:	Ta1103
TVO:	TVG0444310(TVG0444310)
PTO:	PTO0742
FAC:	FACI_IFERC01G1571
FAI:	FAD_0549
CDIV:	CPM_0301
TAR:	TALC_01406
MAX:	MMALV_15110
MER:	MMINT_02260
MEAR:	Mpt1_c00900(gap)
MARC:	AR505_0154
PHO:	PH1830(PH1830)
PAB:	PAB0257(gap)
PFU:	PF1874
PFI:	PFC_09215
PYN:	PNA2_0429
PYA:	PYCH_00860
PYS:	Py04_1761
PYC:	TQ32_07585
TKO:	TK0765
TON:	TON_0639
TGA:	TGAM_1667(gap)
TSI:	TSIB_0949
TBA:	TERMP_00454
THE:	GQS_01790
THA:	TAM4_1537
THM:	CL1_0086
TLT:	OCC_07249
THS:	TES1_0542
TNU:	BD01_0756
TEU:	TEU_08915
TGY:	X802_01260
THV:	ADU37_CDS06300
TCH:	CHITON_2116
TPEP:	A0127_01245
PPAC:	PAP_02855
ABI:	Aboo_0431
ACF:	AciM339_0618
APE:	APE_0171.1
ACJ:	ACAM_0134
SMR:	Smar_0241
SHC:	Shell_0576
IHO:	Igni_1001
IIS:	EYM_03900
DKA:	DKAM_0185
DFD:	Desfe_0262
DMU:	Desmu_0845
TAG:	Tagg_0301
THG:	TCELL_1375
HBU:	Hbut_0939
PFM:	Pyrfu_1285
PDL:	Pyrde_1673
SSO:	SSO0528(gap)
SOL:	Ssol_1613
SSOA:	SULA_1640
SSOL:	SULB_1641
SSOF:	SULC_1639
STO:	STK_13560(gap)
SAI:	Saci_1356
SACN:	SacN8_06615
SACR:	SacRon12I_06605
SACS:	SUSAZ_06485
SIS:	LS215_1689
SIA:	M1425_1581
SIM:	M1627_1697
SID:	M164_1578
SIY:	YG5714_1585
SIN:	YN1551_1251
SII:	LD85_1789
SIH:	SiH_1548
SIR:	SiRe_1456
SIC:	SiL_1458
SULA:	BFU36_04430
MSE:	Msed_1652
MCN:	Mcup_0577
AHO:	Ahos_1308
AMAN:	B6F84_10980
PAI:	PAE1740
PIS:	Pisl_1710
PCL:	Pcal_0632
PAS:	Pars_0743
PYR:	P186_0070
POG:	Pogu_1600
TNE:	Tneu_0730
PYW:	PYWP30_00779
CMA:	Cmaq_1790
TUZ:	TUZN_2003
TTN:	TTX_1534(gap)
VDI:	Vdis_1977
VMO:	VMUT_0389
TPE:	Tpen_0757 Tpen_1765
ASC:	ASAC_0892
CLG:	Calag_0739
FFO:	FFONT_0242
NMR:	Nmar_0831
NID:	NPIRD3C_1371
NIN:	NADRNF5_1235
NKR:	NKOR_04585
NCT:	NMSP_0789(gap)
CSY:	CENSYa_0972
NGA:	Ngar_c16720(gap)
NVN:	NVIE_005380(gap)
NEV:	NTE_01905
TAA:	NMY3_03314
CSU:	CSUB_C1460
NBV:	T478_0731
TAH:	SU86_001980
NDV:	NDEV_1047(gap)
NAC:	AQV86_01560
KCR:	Kcr_0230
BARC:	AOA65_1541(gap)
HAH:	Halar_3698

» show all

Reference

Authors

Valverde, F., Losada, M. and Serrano, A.

Title

Cloning by functional complementation in E. coli of the gap2 gene of Synechocystis PCC 6803 supports an amphibolic role for cyanobacterial NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.

Journal

In: P. Mathis (Ed.), Photosynthesis: From Light to Biosphere, vol. 1, Kluwer Academic Publishers, 1995, p. 959-962.

Reference

2 [PMID:9226260]

Authors

Valverde F, Losada M, Serrano A.

Title

Functional complementation of an Escherichia coli gap mutant supports an amphibolic role for NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase of Synechocystis sp. strain PCC 6803.

Journal

J. Bacteriol. 179 (1997) 4513-22.

Sequence

[syn:sll1342]

Other DBs

ExplorEnz - The Enzyme Database:

1.2.1.59

IUBMB Enzyme Nomenclature:

1.2.1.59

ExPASy - ENZYME nomenclature database:

1.2.1.59

BRENDA, the Enzyme Database:

1.2.1.59

CAS:

39369-25-0

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REACTION: R01061

Entry

R01061 Reaction

Name

D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)

Definition

D-Glyceraldehyde 3-phosphate + Orthophosphate + NAD+ <=> 3-Phospho-D-glyceroyl phosphate + NADH + H+

Equation

C00118 + C00009 + C00003 <=> C00236 + C00004 + C00080

Comment

NADP+ (ec 1.2.1.59, see R01063)

Reaction class

RC00001	C00003_C00004
RC00149	C00118_C00236

Enzyme

1.2.1.12 1.2.1.59

Pathway

rn00010	Glycolysis / Gluconeogenesis
rn00710	Carbon fixation in photosynthetic organisms
rn01100	Metabolic pathways
rn01110	Biosynthesis of secondary metabolites
rn01120	Microbial metabolism in diverse environments
rn01130	Biosynthesis of antibiotics
rn01200	Carbon metabolism
rn01230	Biosynthesis of amino acids

Module

M00001	Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
M00002	Glycolysis, core module involving three-carbon compounds
M00003	Gluconeogenesis, oxaloacetate => fructose-6P
M00165	Reductive pentose phosphate cycle (Calvin cycle)
M00166	Reductive pentose phosphate cycle, ribulose-5P => glyceraldehyde-3P
M00308	Semi-phosphorylative Entner-Doudoroff pathway, gluconate => glycerate-3P
M00552	D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P

Orthology

K00134	glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
K00150	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) [EC:1.2.1.59]
K10705	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic [EC:1.2.1.12]

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (23)   
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Chemical substance (6)   
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Chemical reaction (5)   
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Gene (7668)   
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REACTION: R01063

Entry

R01063 Reaction

Name

D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating)

Definition

D-Glyceraldehyde 3-phosphate + Orthophosphate + NADP+ <=> 3-Phospho-D-glyceroyl phosphate + NADPH + H+

Equation

C00118 + C00009 + C00006 <=> C00236 + C00005 + C00080

Comment

NAD+ (ec 1.2.1.59, see R01061)

Reaction class

RC00001	C00005_C00006
RC00149	C00118_C00236

Enzyme

1.2.1.13 1.2.1.59

Pathway

rn00010	Glycolysis / Gluconeogenesis
rn00710	Carbon fixation in photosynthetic organisms
rn01100	Metabolic pathways
rn01110	Biosynthesis of secondary metabolites
rn01120	Microbial metabolism in diverse environments
rn01130	Biosynthesis of antibiotics
rn01200	Carbon metabolism
rn01230	Biosynthesis of amino acids

Module

M00001	Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
M00002	Glycolysis, core module involving three-carbon compounds
M00003	Gluconeogenesis, oxaloacetate => fructose-6P
M00165	Reductive pentose phosphate cycle (Calvin cycle)
M00166	Reductive pentose phosphate cycle, ribulose-5P => glyceraldehyde-3P

Orthology

K00150	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) [EC:1.2.1.59]
K05298	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) [EC:1.2.1.13]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (21)   
   KEGG PATHWAY (16)   
   KEGG MODULE (5)   
Chemical substance (6)   
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Chemical reaction (5)   
   KEGG ENZYME (2)   
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Gene (585)   
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