KEGG   ORTHOLOGY: K00217Help
Entry
K00217                      KO                                     

Name
E1.3.1.32
Definition
maleylacetate reductase [EC:1.3.1.32]
Pathway
Chlorocyclohexane and chlorobenzene degradation
Benzoate degradation
Fluorobenzoate degradation
Toluene degradation
Metabolic pathways
Microbial metabolism in diverse environments
Degradation of aromatic compounds
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K00217  E1.3.1.32; maleylacetate reductase
   00364 Fluorobenzoate degradation
    K00217  E1.3.1.32; maleylacetate reductase
   00361 Chlorocyclohexane and chlorobenzene degradation
    K00217  E1.3.1.32; maleylacetate reductase
   00623 Toluene degradation
    K00217  E1.3.1.32; maleylacetate reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.32  maleylacetate reductase
     K00217  E1.3.1.32; maleylacetate reductase
BRITE hierarchy
Other DBs
Genes
PKC: 
PKB_3277(clce1) PKB_3626(clce3)
REU: 
REH: 
H16_A1786(h16_A1786) H16_B0970(pcpE)
RME: 
Rmet_5063(macA)
BUR: 
BAM: 
BXE: 
Bxe_A1126(clcE)
BXB: 
DR64_3286(tfdF)
BPT: 
AXY: 
AXYL_06557(tftE2)
PNA: 
VEI: 
LCH: 
RLE: 
pRL120100(tftE2) pRL120215(tftE1)
BJA: 
BRA: 
RPE: 
MSM: 
CGL: 
NCgl1112(Cgl1159)
CGB: 
cg1310(tfdF) cg3386(tcbF)
CGU: 
WA5_1112(TfdF)
CGT: 
CGS: 
CGG: 
CGM: 
cgp_1310(tfdF)
RHA: 
SSO: 
SSO2490(clcE)
SAI: 
MSE: 
 » show all
TaxonomyKoalaUniProt

KEGG   ENZYME: 1.3.1.32Help
Entry
EC 1.3.1.32                 Enzyme                                 

Name
maleylacetate reductase;
maleolylacetate reductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
3-oxoadipate:NAD(P)+ oxidoreductase
Reaction(IUBMB)
3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+ [RN:R02988 R02989]
Reaction(KEGG)
Substrate
3-oxoadipate [CPD:C00846];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
2-maleylacetate [CPD:C02222];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.3.1.32 created 1983
Pathway
Chlorocyclohexane and chlorobenzene degradation
Benzoate degradation
Fluorobenzoate degradation
Toluene degradation
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K00217  
maleylacetate reductase
Genes
PKC: 
PKB_3277(clce1) PKB_3626(clce3)
REU: 
REH: 
H16_A1786(h16_A1786) H16_B0970(pcpE)
RME: 
Rmet_5063(macA)
BUR: 
BAM: 
BXE: 
Bxe_A1126(clcE)
BXB: 
DR64_3286(tfdF)
BPT: 
AXY: 
AXYL_06557(tftE2)
PNA: 
VEI: 
LCH: 
RLE: 
pRL120100(tftE2) pRL120215(tftE1)
BJA: 
BRA: 
RPE: 
MSM: 
CGL: 
NCgl1112(Cgl1159)
CGB: 
cg1310(tfdF) cg3386(tcbF)
CGU: 
WA5_1112(TfdF)
CGT: 
CGS: 
CGG: 
CGM: 
cgp_1310(tfdF)
RHA: 
SSO: 
SSO2490(clcE)
SAI: 
MSE: 
 » show all
Taxonomy
Reference
1  [PMID:7387635]
  Authors
Gaal AB, Neujahr HY.
  Title
Maleylacetate reductase from Trichosporon cutaneum.
  Journal
Biochem. J. 185 (1980) 783-6.
Reference
2
  Authors
Gaal, A.B. and Neujahr, H.Y.
  Title
Induction of phenol-metabolizing enzymes in Trichosporon cutaneum.
  Journal
Arch. Microbiol. 130 (1981) 54-58.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
69669-65-4

KEGG   REACTION: R09224Help
Entry
R09224                      Reaction                               

Name
maleylacetate reductase
Definition
5-Methylmaleylacetate + NADH + H+ <=> 2-Methyl-3-oxoadipate + NAD+
Equation
Reaction class
C00003_C00004
C18306_C18307
Enzyme
Pathway
Toluene degradation
Microbial metabolism in diverse environments
Orthology
K00217  
maleylacetate reductase [EC:1.3.1.32]

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