KEGG   ORTHOLOGY: K00512Help
Entry
K00512                      KO                                     
Name
CYP17
Definition
cytochrome P450, family 17, subfamily A (steroid 17alpha-monooxygenase) [EC:1.14.99.9]
Pathway
Steroid hormone biosynthesis
Ovarian steroidogenesis
Module
M00109  
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
M00110  
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
Disease
H00216  
Congenital adrenal hyperplasia (CAH)
H00608  
46,XY disorders of sex development (Disorders in androgen synthesis or action)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    K00512  CYP17; cytochrome P450, family 17, subfamily A (steroid 17alpha-monooxygenase)
 Organismal Systems
  Endocrine system
   04913 Ovarian Steroidogenesis
    K00512  CYP17; cytochrome P450, family 17, subfamily A (steroid 17alpha-monooxygenase)
KEGG pathway modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Sterol biosynthesis
    M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
     K00512  CYP17; cytochrome P450, family 17, subfamily A (steroid 17alpha-monooxygenase)
    M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
     K00512  CYP17; cytochrome P450, family 17, subfamily A (steroid 17alpha-monooxygenase)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors with incorporation of molecular oxygen
   1.14.99  Miscellaneous
    1.14.99.9  steroid 17alpha-monooxygenase
     K00512  CYP17; cytochrome P450, family 17, subfamily A (steroid 17alpha-monooxygenase)
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP17 family
   CYP17A subfamily
    K00512  CYP17; cytochrome P450, family 17, subfamily A (steroid 17alpha-monooxygenase)
BRITE hierarchy
Other DBs
Genes
HSA: 
1586(CYP17A1)
PTR: 
450141(CYP17A1)
PPS: 
GGO: 
PON: 
MCC: 
678693(CYP17A1)
MMU: 
13074(Cyp17a1)
RNO: 
25146(Cyp17a1)
CFA: 
477807(CYP17A1)
AML: 
FCA: 
493967(CYP17A1)
BTA: 
281739(CYP17A1) 782561(CYP17A1) 784256
SSC: 
403330(CYP17A1)
ECB: 
100034232(CYP17A1)
SHR: 
100915970
OAA: 
100080906
GGA: 
425056(CYP17A1)
MGP: 
100540331
ACS: 
100553634 100553834
XLA: 
100036774(cyp17a1)
XTR: 
100145650(cyp17a1)
DRE: 
399692(cyp17a1)
TRU: 
100125798(cyp17a1)
OLA: 
100125816(cyp17)
BFO: 
BRAFLDRAFT_94132
 » show all
TaxonomyKoalaUniProt
Reference
PMID:6966286
  Authors
Yoshida KI, Oshima H, Troen P
  Title
Studies of the human testis. XIII. Properties of nicotinamide adenine dinucleotide (reduced form)-linked 17 alpha-hydroxylation.
  Journal
J Clin Endocrinol Metab 50:895-9 (1980)
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