KEGG   ORTHOLOGY: K01721Help
Entry
K01721                      KO                                     

Name
nthA
Definition
nitrile hydratase subunit alpha [EC:4.2.1.84]
Pathway
Fluorobenzoate degradation
Tryptophan metabolism
Aminobenzoate degradation
Styrene degradation
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Amino acid metabolism
   00380 Tryptophan metabolism
    K01721  nthA; nitrile hydratase subunit alpha
  Xenobiotics biodegradation and metabolism
   00627 Aminobenzoate degradation
    K01721  nthA; nitrile hydratase subunit alpha
   00364 Fluorobenzoate degradation
    K01721  nthA; nitrile hydratase subunit alpha
   00643 Styrene degradation
    K01721  nthA; nitrile hydratase subunit alpha
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.84  nitrile hydratase
     K01721  nthA; nitrile hydratase subunit alpha
BRITE hierarchy
Other DBs
Genes
KPK: 
KPE: 
KPK_2672(nthA)
KVA: 
KVD: 
KOX: 
KOE: 
KOY: 
KOK: 
KOC: 
KOM: 
RON: 
TE10_14490
KRD: 
A3780_03620
SRY: 
M621_16750
PVA: 
Pvag_pPag20175(nthA)
PAO: 
Pat9b_4154
PPF: 
Pput_2728
PPB: 
PPUBIRD1_2723
PPI: 
YSA_10157
PFS: 
PFLU_3209
PFW: 
PF1751_v1c35570(nthA)
PFF: 
PFLUOLIPICF718110
PFX: 
A7318_17640
PPUU: 
PputUW4_03351(nthA)
PSK: 
U771_17950
PSW: 
LK03_13760
PPV: 
NJ69_09925
PFK: 
PFAS1_24110
ACI: 
ACIAD1616(nthA)
MPQ: 
ABA45_07945
HAA: 
A5892_00330
RSL: 
RPSI07_2729(nthA)
CBW: 
RR42_s1766
CCUP: 
BKK81_18935
BCN: 
Bcen_4082
BCH: 
Bcen2424_4284
BCM: 
Bcenmc03_3233
BAM: 
Bamb_6544
BAC: 
BamMC406_6258
BCEP: 
APZ15_17550
BCON: 
NL30_05555
BSEM: 
WJ12_26905
BMEC: 
WJ16_18465
BGD: 
bgla_2g08610
BYI: 
BYI23_B008610
BUO: 
BRPE64_BCDS04570 BRPE64_ECDS01640
BUE: 
BRPE67_BCDS12670
BUQ: 
AC233_09560
BPX: 
BUPH_01711
BPY: 
Bphyt_5089 Bphyt_7181
BCAI: 
K788_0005341
PTX: 
ABW99_04530
BPT: 
Bpet1416(nthA)
AAA: 
Acav_2431
VAP: 
Vapar_1665 Vapar_2111
VPE: 
Varpa_1815
VPD: 
VAPA_1c17540
LIM: 
L103DPR2_00216(nhhA)
LIH: 
L63ED372_00221(nhhA)
HSE: 
Hsero_0932(nthA)
HSZ: 
ACP92_04665
HRB: 
Hrubri_2877(nthA)
MLO: 
mll1425
MLN: 
A9174_18940
MCI: 
Mesci_3246
MOP: 
Mesop_3638
MAM: 
Mesau_03512
MAMO: 
A6B35_22475
MESO: 
BSQ44_16035
MESW: 
A9K65_017575
HOE: 
IMCC20628_02590
AAK: 
AA2016_2873
SME: 
SMc01424(nthA)
SMK: 
Sinme_2084
SMQ: 
SinmeB_1928
SMX: 
SM11_chr1213(nthA)
SMI: 
BN406_01929(nthA)
SMEG: 
C770_GR4Chr2160
SMEL: 
SM2011_c01424(nthA)
SMER: 
DU99_11845
SMD: 
Smed_2001
RHI: 
NGR_c20120(nthA)
SFH: 
SFHH103_01945(nthA)
SFD: 
USDA257_c44280(nthA)
SAME: 
SAMCFNEI73_Ch2388(nthA)
EAD: 
OV14_3492(nthA)
ARA: 
Arad_2890(nthA)
AGC: 
BSY240_266(nthA)
RET: 
RHE_CH02783(nthA)
REC: 
RHECIAT_CH0002924(nthA)
REL: 
REMIM1_CH02826(nthA)
REI: 
IE4771_CH02949(nthA) IE4771_PE00113
REP: 
IE4803_CH02919(nthA)
RLE: 
RL3239(nthA) pRL110124
RLT: 
Rleg2_2526 Rleg2_4711
RLG: 
Rleg_2785 Rleg_6981
RLB: 
RLEG3_24485
RLU: 
RLEG12_23755
RTR: 
RTCIAT899_CH10995(nthA)
RIR: 
BN877_p0388(nthA)
RHL: 
LPU83_2667(nthA)
RGA: 
RGR602_CH02433(nthA)
RHN: 
AMJ98_CH02945(nthA)
RPHA: 
AMC79_CH02937(nthA)
RHT: 
NT26_2093(nthA)
RHX: 
AMK02_CH02874(nthA)
NGL: 
RG1141_CH20250
NGG: 
RG540_CH21180
SHZ: 
shn_11025
BJA: 
bll4498(nthA)
BJU: 
BJ6T_52440
BJP: 
RN69_25545
BRA: 
BRADO3845(nthA)
BBT: 
BBta_4085(nthA)
BRS: 
S23_36770(nthA)
AOL: 
S58_38940
BRC: 
BCCGELA001_18985
BRAD: 
BF49_7011
BIC: 
LMTR13_20375
RPA: 
RPA2805(nthA)
RPB: 
RPB_2704
RPC: 
RPC_2748
RPD: 
RPD_2746
RPT: 
Rpal_3145
RPX: 
Rpdx1_2699
BOP: 
AXW83_16920
BOS: 
BSY19_44(nthA)
BVV: 
BHK69_01490
AZC: 
AZC_3797
MRD: 
Mrad2831_0904
MET: 
M446_6960
MPO: 
Mpop_3787
MNO: 
Mnod_7674
MOR: 
MOC_1118
MAQU: 
Maq22A_c20570
MSL: 
Msil_3460
CHEL: 
AL346_03505
CDQ: 
BOQ54_14255
RVA: 
Rvan_0450
RHZ: 
RHPLAN_13930
RBM: 
TEF_07505
SIL: 
SPO1314(nthA)
SIT: 
TM1040_1972
RMB: 
K529_004210
RDE: 
RD1_1908(nthA)
RLI: 
RLO149_c010030
DSH: 
Dshi_1849(nthA)
PGA: 
PGA1_c23880(nthA)
PGL: 
PGA2_c21900(nthA)
PGD: 
Gal_01003
PHP: 
PhaeoP97_02256(nthA)
OAT: 
OAN307_c21750
OAR: 
OA238_c10400 OA238_c26170
OTM: 
OSB_19900
LMD: 
METH_05510
PTP: 
RCA23_c18250(nthA)
HAT: 
RC74_14255
LAP: 
ACP90_19255
LAGG: 
B0E33_02935
YAN: 
AYJ57_17745
SUAM: 
BOO69_05585
TOM: 
BWR18_04695
RMM: 
ROSMUCSMR3_02599
SPHR: 
BSY17_2186(nthA)
ACR: 
Acry_1077
AMV: 
ACMV_08140
RGI: 
RGI145_12625
ABS: 
AZOBR_p310181(nthA)
TMO: 
TMO_0455(nthA) TMO_b0395(nthA)
PGV: 
SL003B_0819
APB: 
SAR116_1730
MSM: 
MSMEG_0378(nthA)
MSG: 
MSMEI_0371
MSB: 
LJ00_01890
MSN: 
LI99_01890
MSH: 
LI98_01890
MSA: 
Mycsm_00849 Mycsm_04143
MVA: 
Mvan_0648 Mvan_5825
MGI: 
Mflv_1011
MSP: 
Mspyr1_51780
MRH: 
MycrhN_5396
MNE: 
D174_04460
MYE: 
AB431_05955 AB431_20485
MGO: 
AFA91_08840
RHA: 
RHA1_ro00360(nthA)
RER: 
RER_59240(nha1)
REY: 
O5Y_28515
REB: 
XU06_28845
ROA: 
Pd630_LPD04521
GPO: 
GPOL_c06980(nthA)
SVL: 
Strvi_5572
SHY: 
SHJG_0832
SHO: 
SHJGH_0665
SRC: 
M271_41235
SALU: 
DC74_1033
SALL: 
SAZ_05640
SCX: 
AS200_27805
SGS: 
AVL59_29940
SLS: 
SLINC_3328
AAU: 
AAur_pTC20145(nthB) AAur_pTC20146(nthA)
PSIM: 
KR76_24365
GOB: 
Gobs_2330
MMAR: 
MODMU_1179(nthA)
AMQ: 
AMETH_4607
PDX: 
Psed_1451 Psed_1499 Psed_1630 Psed_3243 Psed_3917 Psed_5953 Psed_6005
PSEA: 
WY02_07560 WY02_20685
PSEE: 
FRP1_06445 FRP1_11845 FRP1_22640
PSEH: 
XF36_03270 XF36_16140 XF36_16155 XF36_17890 XF36_20975
PSEQ: 
AD006_01830 AD006_14065 AD006_19130
PECQ: 
AD017_09655 AD017_21890 AD017_26970
KPHY: 
AOZ06_41875
LED: 
BBK82_00005
RXY: 
Rxyl_2315
SYP: 
SYNPCC7002_D0007(nthA)
CMP: 
Cha6605_2559
LBO: 
LBWT_14000
PSEU: 
Pse7367_1909 Pse7367_2071
AMR: 
AM1_1194(nthA)
GLP: 
Glo7428_4955
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2659343
  Authors
Ikehata O, Nishiyama M, Horinouchi S, Beppu T
  Title
Primary structure of nitrile hydratase deduced from the nucleotide sequence of a  Rhodococcus species and its expression in Escherichia coli.
  Journal
Eur J Biochem 181:563-70 (1989)
DOI:10.1111/j.1432-1033.1989.tb14761.x
  Sequence
[rer:RER_59240]
KEGG   ORTHOLOGY: K20807Help
Entry
K20807                      KO                                     

Name
nthB
Definition
nitrile hydratase subunit beta [EC:4.2.1.84]
Pathway
Fluorobenzoate degradation
Tryptophan metabolism
Aminobenzoate degradation
Styrene degradation
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Amino acid metabolism
   00380 Tryptophan metabolism
    K20807  nthB; nitrile hydratase subunit beta
  Xenobiotics biodegradation and metabolism
   00627 Aminobenzoate degradation
    K20807  nthB; nitrile hydratase subunit beta
   00364 Fluorobenzoate degradation
    K20807  nthB; nitrile hydratase subunit beta
   00643 Styrene degradation
    K20807  nthB; nitrile hydratase subunit beta
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.84  nitrile hydratase
     K20807  nthB; nitrile hydratase subunit beta
BRITE hierarchy
Other DBs
Genes
KPK: 
KPE: 
KPK_2673(nthB)
KVA: 
KVD: 
KVQ: 
KOX: 
KOE: 
KOY: 
KOK: 
KOC: 
KOM: 
HR38_18820
RON: 
TE10_14485
KRD: 
A3780_03625
SRY: 
M621_16745
PVA: 
Pvag_pPag20176(nthB)
PAO: 
Pat9b_4153
PPF: 
Pput_2729
PPB: 
PPUBIRD1_2724
PPI: 
YSA_10156
PFS: 
PFLU_3210
PFW: 
PF1751_v1c35580(nthB)
PFF: 
PFLUOLIPICF718105
PFX: 
A7318_17635
PPUU: 
PputUW4_03352(nthB)
PSK: 
U771_17955
PSW: 
LK03_13765
PPV: 
NJ69_09930
PFK: 
PFAS1_24105
ACI: 
ACIAD1615(nthB)
MPQ: 
ABA45_07940
HAA: 
A5892_00325
RSL: 
RPSI07_2728(nthB)
CBW: 
RR42_s1767
CCUP: 
BKK81_18940
BCN: 
Bcen_4083
BCH: 
Bcen2424_4283
BCM: 
Bcenmc03_3234
BAM: 
Bamb_6543
BAC: 
BamMC406_6257
BCEP: 
APZ15_17555
BCON: 
NL30_05560
BSEM: 
WJ12_26900
BMEC: 
WJ16_18470
BGD: 
bgla_2g08620
BYI: 
BYI23_B008600
BUO: 
BRPE64_BCDS04580 BRPE64_ECDS01630
BUE: 
BRPE67_BCDS12660
BUQ: 
AC233_09555
BPX: 
BUPH_08137
BPY: 
Bphyt_5090 Bphyt_7182
BCAI: 
K788_0005342
PTX: 
ABW99_04535
BPT: 
Bpet1415(nthB)
AAA: 
Acav_2430
VAP: 
Vapar_1666 Vapar_2112
VPE: 
Varpa_1816
VPD: 
VAPA_1c17550
LIM: 
L103DPR2_00217
LIH: 
L63ED372_00222(nthB)
HSE: 
Hsero_0931(nthB)
HSZ: 
ACP92_04660
HRB: 
Hrubri_2878(nthB)
MLO: 
mll1423
MLN: 
A9174_18945
MCI: 
Mesci_3247
MOP: 
Mesop_3639
MAM: 
Mesau_03513
MAMO: 
A6B35_22470
MESO: 
BSQ44_16030
MESW: 
A9K65_017580
HOE: 
IMCC20628_02589
AAK: 
AA2016_2874
SME: 
SMc01423(nthB)
SMK: 
Sinme_2083
SMQ: 
SinmeB_1927
SMX: 
SM11_chr1214(nthB)
SMI: 
BN406_01927(nthB)
SMEG: 
C770_GR4Chr2159
SMEL: 
SM2011_c01423(nthB)
SMER: 
DU99_11840
SMD: 
Smed_2000
RHI: 
NGR_c20110(nthB)
SFH: 
SFHH103_01944(nthB)
SFD: 
USDA257_c44270(nthB)
SAME: 
SAMCFNEI73_Ch2387(nthB)
EAD: 
OV14_3491(nthB)
EAH: 
FA04_10460
ARA: 
Arad_2889(nthB)
AGC: 
BSY240_267(nthB)
RET: 
RHE_CH02782(nthB)
REC: 
RHECIAT_CH0002923(nthB)
REL: 
REMIM1_CH02825(nthB)
REI: 
IE4771_CH02948(nthB) IE4771_PE00114
REP: 
IE4803_CH02918(nthB)
RLE: 
RL3238(nhb2) pRL110125
RLT: 
Rleg2_2525 Rleg2_4710
RLG: 
Rleg_2784 Rleg_6980
RLB: 
RLEG3_24480
RLU: 
RLEG12_23750
RTR: 
RTCIAT899_CH10990(nthB)
RIR: 
BN877_p0387(nthB)
RHL: 
LPU83_2666(nthB)
RGA: 
RGR602_CH02432(nthB)
RHN: 
AMJ98_CH02944(nthB)
RPHA: 
AMC79_CH02936(nthB)
RHT: 
NT26_2092(nthB)
RHX: 
AMK02_CH02873(nthB)
NGL: 
RG1141_CH20240
NGG: 
RG540_CH21170
SHZ: 
shn_11020
BJA: 
bll4497(nthB)
BJU: 
BJ6T_52450
BJP: 
RN69_25550
BRA: 
BRADO3846(nthB)
BBT: 
BBta_4084(nthB)
BRS: 
S23_36780(nthB)
AOL: 
S58_38950
BRC: 
BCCGELA001_18980
BRAD: 
BF49_7012
BIC: 
LMTR13_20380
RPA: 
RPA2806(nthB)
RPB: 
RPB_2705
RPC: 
RPC_2749
RPD: 
RPD_2747
RPT: 
Rpal_3146
RPX: 
Rpdx1_2698
BOP: 
AXW83_16925
BOS: 
BSY19_45(nthB)
BVV: 
BHK69_01495
AZC: 
AZC_3798
MRD: 
Mrad2831_0905
MET: 
M446_6961
MPO: 
Mpop_3786
MNO: 
Mnod_7675
MOR: 
MOC_1119
MAQU: 
Maq22A_c20575
MSL: 
Msil_3459
CHEL: 
AL346_03500
CDQ: 
BOQ54_14250
RHZ: 
RHPLAN_13920 RHPLAN_42290
RBM: 
TEF_07500
SIL: 
SPO1315(nthB)
SIT: 
TM1040_1971
RMB: 
K529_004215
RDE: 
RD1_1909(nthB)
RLI: 
RLO149_c010040(nthB) RLO149_c040200 RLO149_c040210
PGA: 
PGA1_c23870(nthB)
PGL: 
PGA2_c21890(nthB)
PGD: 
Gal_01004
PHP: 
PhaeoP97_02255(nthB)
OAT: 
OAN307_c21760 OAN307_c21770
OAR: 
OA238_c10410 OA238_c26160
OTM: 
OSB_19880(nthB_1) OSB_19890(nthB_2)
LMD: 
METH_05515
PTP: 
RCA23_c18240
HAT: 
RC74_14250
LAP: 
ACP90_19260
LAGG: 
B0E33_02940
YAN: 
AYJ57_17740
SUAM: 
BOO69_05590
TOM: 
BWR18_04700
RMM: 
ROSMUCSMR3_02600(nthB)
SPHR: 
BSY17_2185(nthB)
AMV: 
ACMV_08120 ACMV_08130
RGI: 
RGI145_12630 RGI145_12635
ABS: 
AZOBR_p310180
TMO: 
TMO_0454(nthB) TMO_b0396
PGV: 
SL003B_0818(nthB)
MSM: 
MSMEG_0377
MSG: 
MSMEI_0370
MSB: 
LJ00_01885
MSN: 
LI99_01885
MSH: 
LI98_01885
MSA: 
Mycsm_00848 Mycsm_04142
MVA: 
Mvan_0647 Mvan_5826
MGI: 
Mflv_1010
MSP: 
Mspyr1_51790
MRH: 
MycrhN_5395
MNE: 
D174_04455
MYE: 
AB431_05950 AB431_20480
MGO: 
AFA91_08835
RHA: 
RHA1_ro00361(nthB)
RER: 
RER_59250(nha2)
REY: 
O5Y_28520
REB: 
XU06_28850
ROA: 
Pd630_LPD04522
GPO: 
GPOL_c06990(nthB)
SVL: 
Strvi_5573
SRC: 
M271_41230
SALU: 
DC74_1032
SALL: 
SAZ_05635
SCX: 
AS200_27795 AS200_27800
SGS: 
AVL59_29935
SLS: 
SLINC_3329 SLINC_3330
AAU: 
AAur_pTC20147(nthB)
PSIM: 
KR76_24370
AMQ: 
AMETH_4608
PDX: 
Psed_1452 Psed_1500 Psed_1631 Psed_3242 Psed_3916 Psed_5954 Psed_6004
PSEA: 
WY02_07565 WY02_15155
PSEE: 
FRP1_06440 FRP1_11850 FRP1_22645
PSEH: 
XF36_03265 XF36_16160 XF36_17895 XF36_20980
PSEQ: 
AD006_01835 AD006_14060 AD006_19125
PECQ: 
AD017_09660 AD017_21885 AD017_26965
KPHY: 
AOZ06_41880 AOZ06_41885
SYP: 
SYNPCC7002_D0008(nthB)
CMP: 
Cha6605_2558
LBO: 
LBWT_14010
PSEU: 
Pse7367_1910 Pse7367_2072
AMR: 
AM1_1195(nthB)
GLP: 
Glo7428_4954
HAH: 
Halar_0762
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2659343
  Authors
Ikehata O, Nishiyama M, Horinouchi S, Beppu T
  Title
Primary structure of nitrile hydratase deduced from the nucleotide sequence of a  Rhodococcus species and its expression in Escherichia coli.
  Journal
Eur J Biochem 181:563-70 (1989)
DOI:10.1111/j.1432-1033.1989.tb14761.x
  Sequence
[rer:RER_59250]
KEGG   ENZYME: 4.2.1.84Help
Entry
EC 4.2.1.84                 Enzyme                                 

Name
nitrile hydratase;
nitrilase (ambiguous);
3-cyanopyridine hydratase;
NHase;
L-NHase;
H-NHase;
acrylonitrile hydratase;
aliphatic nitrile hydratase;
nitrile hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
aliphatic-amide hydro-lyase (nitrile-forming)
Reaction(IUBMB)
an aliphatic amide = a nitrile + H2O [RN:R02826]
Reaction(KEGG)
Substrate
aliphatic amide [CPD:C02244]
Product
nitrile [CPD:C00726];
H2O [CPD:C00001]
Comment
Acts on short-chain aliphatic nitriles, converting them into the corresponding amides. Does not act on these amides or on aromatic nitriles. cf. EC 3.5.5.1 nitrilase.
History
EC 4.2.1.84 created 1989
Pathway
Fluorobenzoate degradation
Tryptophan metabolism
Aminobenzoate degradation
Styrene degradation
Microbial metabolism in diverse environments
Orthology
K01721  
nitrile hydratase subunit alpha
K20807  
nitrile hydratase subunit beta
Genes
KPK: 
KPE: 
KPK_2672(nthA) KPK_2673(nthB)
KVA: 
KVD: 
KVQ: 
KOX: 
KOE: 
KOY: 
KOK: 
KOC: 
KOM: 
HR38_18820 HR38_18825
RON: 
TE10_14485 TE10_14490
KRD: 
A3780_03620 A3780_03625
SRY: 
M621_16745 M621_16750
PVA: 
Pvag_pPag20175(nthA) Pvag_pPag20176(nthB)
PAO: 
Pat9b_4153 Pat9b_4154
PPF: 
Pput_2728 Pput_2729
PPB: 
PPUBIRD1_2723 PPUBIRD1_2724
PPI: 
YSA_10156 YSA_10157
PFS: 
PFLU_3209 PFLU_3210
PFW: 
PF1751_v1c35570(nthA) PF1751_v1c35580(nthB)
PFF: 
PFLUOLIPICF718105 PFLUOLIPICF718110
PFX: 
A7318_17635 A7318_17640
PPUU: 
PputUW4_03351(nthA) PputUW4_03352(nthB)
PSK: 
U771_17950 U771_17955
PSW: 
LK03_13760 LK03_13765
PPV: 
NJ69_09925 NJ69_09930
PFK: 
PFAS1_24105 PFAS1_24110
ACI: 
ACIAD1615(nthB) ACIAD1616(nthA)
MPQ: 
ABA45_07940 ABA45_07945
HAA: 
A5892_00325 A5892_00330
RSL: 
RPSI07_2728(nthB) RPSI07_2729(nthA)
CBW: 
RR42_s1766 RR42_s1767
CCUP: 
BKK81_18935 BKK81_18940
BCN: 
Bcen_4082 Bcen_4083
BCH: 
Bcen2424_4283 Bcen2424_4284
BCM: 
Bcenmc03_3233 Bcenmc03_3234
BAM: 
Bamb_6543 Bamb_6544
BAC: 
BamMC406_6257 BamMC406_6258
BCEP: 
APZ15_17550 APZ15_17555
BCON: 
NL30_05555 NL30_05560
BSEM: 
WJ12_26900 WJ12_26905
BMEC: 
WJ16_18465 WJ16_18470
BGD: 
bgla_2g08610 bgla_2g08620
BYI: 
BYI23_B008600 BYI23_B008610
BUO: 
BRPE64_BCDS04570 BRPE64_BCDS04580 BRPE64_ECDS01630 BRPE64_ECDS01640
BUE: 
BRPE67_BCDS12660 BRPE67_BCDS12670
BUQ: 
AC233_09555 AC233_09560
BPX: 
BUPH_01711 BUPH_08137
BPY: 
Bphyt_5089 Bphyt_5090 Bphyt_7181 Bphyt_7182
BCAI: 
K788_0005341 K788_0005342
PTX: 
ABW99_04530 ABW99_04535
BPT: 
Bpet1415(nthB) Bpet1416(nthA)
AAA: 
Acav_2430 Acav_2431
VAP: 
Vapar_1665 Vapar_1666 Vapar_2111 Vapar_2112
VPE: 
Varpa_1815 Varpa_1816
VPD: 
VAPA_1c17540 VAPA_1c17550
LIM: 
L103DPR2_00216(nhhA) L103DPR2_00217
LIH: 
L63ED372_00221(nhhA) L63ED372_00222(nthB)
HSE: 
Hsero_0931(nthB) Hsero_0932(nthA)
HSZ: 
ACP92_04660 ACP92_04665
HRB: 
Hrubri_2877(nthA) Hrubri_2878(nthB)
MLO: 
mll1423 mll1425
MLN: 
A9174_18940 A9174_18945
MCI: 
Mesci_3246 Mesci_3247
MOP: 
Mesop_3638 Mesop_3639
MAM: 
Mesau_03512 Mesau_03513
MAMO: 
A6B35_22470 A6B35_22475
MESO: 
BSQ44_16030 BSQ44_16035
MESW: 
A9K65_017575 A9K65_017580
HOE: 
IMCC20628_02589 IMCC20628_02590
AAK: 
AA2016_2873 AA2016_2874
SME: 
SMc01423(nthB) SMc01424(nthA)
SMK: 
Sinme_2083 Sinme_2084
SMQ: 
SinmeB_1927 SinmeB_1928
SMX: 
SM11_chr1213(nthA) SM11_chr1214(nthB)
SMI: 
BN406_01927(nthB) BN406_01929(nthA)
SMEG: 
C770_GR4Chr2159 C770_GR4Chr2160
SMEL: 
SM2011_c01423(nthB) SM2011_c01424(nthA)
SMER: 
DU99_11840 DU99_11845
SMD: 
Smed_2000 Smed_2001
RHI: 
NGR_c20110(nthB) NGR_c20120(nthA)
SFH: 
SFHH103_01944(nthB) SFHH103_01945(nthA)
SFD: 
USDA257_c44270(nthB) USDA257_c44280(nthA)
SAME: 
SAMCFNEI73_Ch2387(nthB) SAMCFNEI73_Ch2388(nthA)
EAD: 
OV14_3491(nthB) OV14_3492(nthA)
EAH: 
FA04_10460
ARA: 
Arad_2889(nthB) Arad_2890(nthA)
AGC: 
BSY240_266(nthA) BSY240_267(nthB)
RET: 
RHE_CH02782(nthB) RHE_CH02783(nthA)
REC: 
RHECIAT_CH0002923(nthB) RHECIAT_CH0002924(nthA)
REL: 
REMIM1_CH02825(nthB) REMIM1_CH02826(nthA)
REI: 
IE4771_CH02948(nthB) IE4771_CH02949(nthA) IE4771_PE00113 IE4771_PE00114
REP: 
IE4803_CH02918(nthB) IE4803_CH02919(nthA)
RLE: 
RL3238(nhb2) RL3239(nthA) pRL110124 pRL110125
RLT: 
Rleg2_2525 Rleg2_2526 Rleg2_4710 Rleg2_4711
RLG: 
Rleg_2784 Rleg_2785 Rleg_6980 Rleg_6981
RLB: 
RLEG3_24480 RLEG3_24485
RLU: 
RLEG12_23750 RLEG12_23755
RTR: 
RTCIAT899_CH10990(nthB) RTCIAT899_CH10995(nthA)
RIR: 
BN877_p0387(nthB) BN877_p0388(nthA)
RHL: 
LPU83_2666(nthB) LPU83_2667(nthA)
RGA: 
RGR602_CH02432(nthB) RGR602_CH02433(nthA)
RHN: 
AMJ98_CH02944(nthB) AMJ98_CH02945(nthA)
RPHA: 
AMC79_CH02936(nthB) AMC79_CH02937(nthA)
RHT: 
NT26_2092(nthB) NT26_2093(nthA)
RHX: 
AMK02_CH02873(nthB) AMK02_CH02874(nthA)
NGL: 
RG1141_CH20240 RG1141_CH20250
NGG: 
RG540_CH21170 RG540_CH21180
SHZ: 
shn_11020 shn_11025
BJA: 
bll4497(nthB) bll4498(nthA)
BJU: 
BJ6T_52440 BJ6T_52450
BJP: 
RN69_25545 RN69_25550
BRA: 
BRADO3845(nthA) BRADO3846(nthB)
BBT: 
BBta_4084(nthB) BBta_4085(nthA)
BRS: 
S23_36770(nthA) S23_36780(nthB)
AOL: 
S58_38940 S58_38950
BRC: 
BCCGELA001_18980 BCCGELA001_18985
BRAD: 
BF49_7011 BF49_7012
BIC: 
LMTR13_20375 LMTR13_20380
RPA: 
RPA2805(nthA) RPA2806(nthB)
RPB: 
RPB_2704 RPB_2705
RPC: 
RPC_2748 RPC_2749
RPD: 
RPD_2746 RPD_2747
RPT: 
Rpal_3145 Rpal_3146
RPX: 
Rpdx1_2698 Rpdx1_2699
BOP: 
AXW83_16920 AXW83_16925
BOS: 
BSY19_44(nthA) BSY19_45(nthB)
BVV: 
BHK69_01490 BHK69_01495
AZC: 
AZC_3797 AZC_3798
MRD: 
Mrad2831_0904 Mrad2831_0905
MET: 
M446_6960 M446_6961
MPO: 
Mpop_3786 Mpop_3787
MNO: 
Mnod_7674 Mnod_7675
MOR: 
MOC_1118 MOC_1119
MAQU: 
Maq22A_c20570 Maq22A_c20575
MSL: 
Msil_3459 Msil_3460
CHEL: 
AL346_03500 AL346_03505
CDQ: 
BOQ54_14250 BOQ54_14255
RVA: 
Rvan_0450
RHZ: 
RHPLAN_13920 RHPLAN_13930 RHPLAN_42290
RBM: 
TEF_07500 TEF_07505
SIL: 
SPO1314(nthA) SPO1315(nthB)
SIT: 
TM1040_1971 TM1040_1972
RMB: 
K529_004210 K529_004215
RDE: 
RD1_1908(nthA) RD1_1909(nthB)
RLI: 
RLO149_c010030 RLO149_c010040(nthB) RLO149_c040200 RLO149_c040210
DSH: 
Dshi_1849(nthA)
PGA: 
PGA1_c23870(nthB) PGA1_c23880(nthA)
PGL: 
PGA2_c21890(nthB) PGA2_c21900(nthA)
PGD: 
Gal_01003 Gal_01004
PHP: 
PhaeoP97_02255(nthB) PhaeoP97_02256(nthA)
OAT: 
OAN307_c21750 OAN307_c21760 OAN307_c21770
OAR: 
OA238_c10400 OA238_c10410 OA238_c26160 OA238_c26170
OTM: 
OSB_19880(nthB_1) OSB_19890(nthB_2) OSB_19900
LMD: 
METH_05510 METH_05515
PTP: 
RCA23_c18240 RCA23_c18250(nthA)
HAT: 
RC74_14250 RC74_14255
LAP: 
ACP90_19255 ACP90_19260
LAGG: 
B0E33_02935 B0E33_02940
YAN: 
AYJ57_17740 AYJ57_17745
SUAM: 
BOO69_05585 BOO69_05590
TOM: 
BWR18_04695 BWR18_04700
RMM: 
ROSMUCSMR3_02599 ROSMUCSMR3_02600(nthB)
SPHR: 
BSY17_2185(nthB) BSY17_2186(nthA)
ACR: 
Acry_1077
AMV: 
ACMV_08120 ACMV_08130 ACMV_08140
RGI: 
RGI145_12625 RGI145_12630 RGI145_12635
ABS: 
AZOBR_p310180 AZOBR_p310181(nthA)
TMO: 
TMO_0454(nthB) TMO_0455(nthA) TMO_b0395(nthA) TMO_b0396
PGV: 
SL003B_0818(nthB) SL003B_0819
APB: 
SAR116_1730
MSM: 
MSMEG_0377 MSMEG_0378(nthA)
MSG: 
MSMEI_0370 MSMEI_0371
MSB: 
LJ00_01885 LJ00_01890
MSN: 
LI99_01885 LI99_01890
MSH: 
LI98_01885 LI98_01890
MSA: 
Mycsm_00848 Mycsm_00849 Mycsm_04142 Mycsm_04143
MVA: 
Mvan_0647 Mvan_0648 Mvan_5825 Mvan_5826
MGI: 
Mflv_1010 Mflv_1011
MSP: 
Mspyr1_51780 Mspyr1_51790
MRH: 
MycrhN_5395 MycrhN_5396
MNE: 
D174_04455 D174_04460
MYE: 
AB431_05950 AB431_05955 AB431_20480 AB431_20485
MGO: 
AFA91_08835 AFA91_08840
RHA: 
RHA1_ro00360(nthA) RHA1_ro00361(nthB)
RER: 
RER_59240(nha1) RER_59250(nha2)
REY: 
O5Y_28515 O5Y_28520
REB: 
XU06_28845 XU06_28850
ROA: 
Pd630_LPD04521 Pd630_LPD04522
GPO: 
GPOL_c06980(nthA) GPOL_c06990(nthB)
SVL: 
Strvi_5572 Strvi_5573
SHY: 
SHJG_0832
SHO: 
SHJGH_0665
SRC: 
M271_41230 M271_41235
SALU: 
DC74_1032 DC74_1033
SALL: 
SAZ_05635 SAZ_05640
SCX: 
AS200_27795 AS200_27800 AS200_27805
SGS: 
AVL59_29935 AVL59_29940
SLS: 
SLINC_3328 SLINC_3329 SLINC_3330
AAU: 
AAur_pTC20145(nthB) AAur_pTC20146(nthA) AAur_pTC20147(nthB)
PSIM: 
KR76_24365 KR76_24370
GOB: 
Gobs_2330
MMAR: 
MODMU_1179(nthA)
AMQ: 
AMETH_4607 AMETH_4608
PDX: 
Psed_1451 Psed_1452 Psed_1499 Psed_1500 Psed_1630 Psed_1631 Psed_3242 Psed_3243 Psed_3916 Psed_3917 Psed_5953 Psed_5954 Psed_6004 Psed_6005
PSEA: 
WY02_07560 WY02_07565 WY02_15155 WY02_20685
PSEE: 
FRP1_06440 FRP1_06445 FRP1_11845 FRP1_11850 FRP1_22640 FRP1_22645
PSEH: 
XF36_03265 XF36_03270 XF36_16140 XF36_16155 XF36_16160 XF36_17890 XF36_17895 XF36_20975 XF36_20980
PSEQ: 
AD006_01830 AD006_01835 AD006_14060 AD006_14065 AD006_19125 AD006_19130
PECQ: 
AD017_09655 AD017_09660 AD017_21885 AD017_21890 AD017_26965 AD017_26970
KPHY: 
AOZ06_41875 AOZ06_41880 AOZ06_41885
LED: 
BBK82_00005
RXY: 
Rxyl_2315
SYP: 
SYNPCC7002_D0007(nthA) SYNPCC7002_D0008(nthB)
CMP: 
Cha6605_2558 Cha6605_2559
LBO: 
LBWT_14000 LBWT_14010
PSEU: 
Pse7367_1909 Pse7367_1910 Pse7367_2071 Pse7367_2072
AMR: 
AM1_1194(nthA) AM1_1195(nthB)
GLP: 
Glo7428_4954 Glo7428_4955
HAH: 
Halar_0762
 » show all
Taxonomy
Reference
1
  Authors
Asano, Y., Fujishiro, K., Tani, Y. and Yamada, H.
  Title
Microbial degradation of nitrile compounds. 5. Aliphatic nitrile hydratase from Arthrobacter sp J-1. Purification and characterization.
  Journal
Agric. Biol. Chem. 46 (1982) 1165-1174.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
82391-37-5
KEGG   REACTION: R07780Help
Entry
R07780                      Reaction                               

Name
3,5-dibromo-4-hydroxybenzamide hydro-lyase (nitrile-forming)
Definition
Bromoxynil + H2O <=> 3,5-Dibromo-4-hydroxybenzamide
Equation
Reaction class
C04178_C16246
Enzyme
Pathway
Fluorobenzoate degradation
Microbial metabolism in diverse environments
Orthology
K01721  
nitrile hydratase subunit alpha [EC:4.2.1.84]
K20807  
nitrile hydratase subunit beta [EC:4.2.1.84]
DBGET integrated database retrieval system