KEGG ORTHOLOGY: K01771

ORTHOLOGY: K01771

Entry

K01771 KO

Name

plc

Definition

1-phosphatidylinositol phosphodiesterase [EC:4.6.1.13]

Pathway

ko00562

Inositol phosphate metabolism

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    K01771  plc; 1-phosphatidylinositol phosphodiesterase
Enzymes [BR:ko01000]
4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.13  phosphatidylinositol diacylglycerol-lyase
     K01771  plc; 1-phosphatidylinositol phosphodiesterase

Other DBs

RN:

R03332

GO:

0004436

Genes

OAA:	107547964
GGA:	101751271
MGP:	104912324
CJO:	107317149
ACYG:	106041539
FAB:	107603775
PHI:	106628453
FPG:	106112280
FCH:	106631759
CLV:	106145769
ACS:	100567546
PBI:	103068284
GJA:	107114885 107114896
XLA:	108710460
XTR:	100494672
NPR:	108790680
DRE:	100000275 100006223(si:dkey-266f7.9)
SRX:	107750812 107756887
SANH:	107688224 107693279
SGH:	107589506 107592133 107592465
IPU:	108256182
TRU:	101062629
TNG:	GSTEN00032541G001
LCO:	104927567 104932167
NCC:	104964990 104967986
MZE:	101464692 101486202
OLA:	101162017
XMA:	102223877
CSEM:	103394551
LCF:	108879457 108899480
SASA:	106570214
ELS:	105012651 105014773
SFM:	108930395 108932007 108932008 108938283
LCM:	102353481 102357360 106704972
SKO:	100378443 100378594 102805589
TUT:	107363869
LGI:	LOTGIDRAFT_199696
OBI:	106880796 106880803
LJA:	Lj1g3v3343840.1(Lj1g3v3343840.1)
CCP:	CHC_T00007789001
AGO:	AGOS_AFR607C
ERC:	Ecym_2326
LTH:	KLTH0H11308g
TBL:	TBLA_0G03650(TBLA0G03650)
PPA:	PAS_chr4_0907
DHA:	DEHA2G04180g
PIC:	PICST_70308
PGU:	PGUG_02986
SPAA:	SPAPADRAFT_60801
LEL:	LELG_01298
CAL:	CAALFM_C202600CA(FGR22) CAALFM_C203040WA(PLC2)
CTP:	CTRG_01321 CTRG_01371
COT:	CORT_0A10910
CDU:	CD36_17390(PLC22) CD36_17810
CTEN:	CANTEDRAFT_112125
YLI:	YALI0D10813g
CLU:	CLUG_00951
CAUR:	QG37_01069
NCR:	NCU08982 NCU09135
NTE:	NEUTE1DRAFT149986(NEUTE1DRAFT_149986)
SMP:	SMAC_01937 SMAC_04631
PAN:	PODANSg09605
TTT:	THITE_2010991
MTM:	MYCTH_2294314
CTHR:	CTHT_0073210
MGR:	MGG_04834
TMN:	UCRPA7_1358 UCRPA7_7184 UCRPA7_7913
FGR:	FGSG_00423 FGSG_05655
FPU:	FPSE_00086 FPSE_06249 FPSE_11073
FVR:	FVEG_00884 FVEG_06828 FVEG_08738
FOX:	FOXG_00628 FOXG_09227
NHE:	NECHADRAFT_57455 NECHADRAFT_70960
TRE:	TRIREDRAFT_111102 TRIREDRAFT_57975
MAW:	MAC_02826 MAC_03182 MAC_05413
MAJ:	MAA_04277 MAA_04887 MAA_10423
CMT:	CCM_02309 CCM_09301
VAL:	VDBG_01003 VDBG_06112
VDA:	VDAG_00614 VDAG_03270
CFJ:	CFIO01_03094 CFIO01_12060
ELA:	UCREL1_1181
PFY:	PFICI_01340
SSL:	SS1G_06734 SS1G_12385
BFU:	BC1G_01342 BC1G_14570
MBE:	MBM_05780
PSCO:	LY89DRAFT_648735 LY89DRAFT_690521 LY89DRAFT_691271 LY89DRAFT_708673
GLZ:	GLAREA_11821
ANI:	AN3636.2
AFM:	AFUA_4G12000
AOR:	AOR_1_1798154(AO090003001009)
ANG:	ANI_1_2710014(An01g07280)
AFV:	AFLA_028080
ACT:	ACLA_051030
NFI:	NFIA_104240
PCS:	Pc22g05150
PDP:	PDIP_86100
CIM:	CIMG_01631
CPW:	CPC735_048450
PBL:	PAAG_02760
PBN:	PADG_01787
URE:	UREG_05354
ABE:	ARB_00415
TVE:	TRV_02704
AJE:	HCAG_01498
PNO:	SNOG_06918
PTE:	PTT_15969
BZE:	COCCADRAFT_29910
BSC:	COCSADRAFT_28875
BOR:	COCMIDRAFT_92880
ZTR:	MYCGRDRAFT_107761 MYCGRDRAFT_109874 MYCGRDRAFT_98925
PFJ:	MYCFIDRAFT_189591 MYCFIDRAFT_29247
BCOM:	BAUCODRAFT_144753 BAUCODRAFT_71222
NPA:	UCRNP2_1182
TML:	GSTUM_00011434001
CGI:	CGB_C8350C
TMS:	TREMEDRAFT_25826
TVS:	TRAVEDRAFT_28301
DSQ:	DICSQDRAFT_57461
PCO:	PHACADRAFT_256922
SHS:	STEHIDRAFT_102395 STEHIDRAFT_52122
HIR:	HETIRDRAFT_311254
PSQ:	PUNSTDRAFT_114420
ADL:	AURDEDRAFT_112159 AURDEDRAFT_113803
FME:	FOMMEDRAFT_132498
GTR:	GLOTRDRAFT_137236
LBC:	LACBIDRAFT_308269 LACBIDRAFT_315813 LACBIDRAFT_318365 LACBIDRAFT_335698
MPR:	MPER_09363
MRR:	Moror_14864 Moror_4204
CCI:	CC1G_10832 CC1G_13081
SCM:	SCHCODRAFT_106139 SCHCODRAFT_51562
ABP:	AGABI1DRAFT104838(AGABI1DRAFT_104838) AGABI1DRAFT121976(AGABI1DRAFT_121976)
ABV:	AGABI2DRAFT200290(AGABI2DRAFT_200290) AGABI2DRAFT210674(AGABI2DRAFT_210674)
CPUT:	CONPUDRAFT_48596
SLA:	SERLADRAFT_441016
UMA:	UMAG_04644
PFP:	PFL1_04542
PGR:	PGTG_06638 PGTG_22509
MLR:	MELLADRAFT_116429 MELLADRAFT_84419
TET:	TTHERM_000426139 TTHERM_00426140
TVA:	TVAG_301070 TVAG_372910
YEP:	YE105_C2085
YEY:	Y11_08861
YEL:	LC20_02835(plc) LC20_02836(plc)
YET:	CH48_3722
YAL:	AT01_349
YFR:	AW19_1307
YKR:	CH54_355
YRU:	BD65_1648 BD65_1649
SOD:	Sant_P0333
EPY:	EpC_18250
EPR:	EPYR_01964(plc)
EAM:	EAMY_1766(plc)
EAY:	EAM_1731
ERJ:	EJP617_29000
MMK:	MU9_1927
HSO:	HS_1585
HSM:	HSM_0426
GAN:	UMN179_01455
GHO:	AL542_15205
PMAN:	OU5_0316
PRR:	AT705_21210
MVS:	MVIS_0305
MDH:	AYM39_00650 AYM39_02300
OAI:	OLEAN_C15740(plcA)
GSN:	YC6258_03989
BVI:	Bcep1808_5289
BVE:	AK36_3592
BUR:	Bcep18194_B0943
BCN:	Bcen_3596
BCH:	Bcen2424_4771
BCM:	Bcenmc03_5512
BCJ:	BCAM1969
BCEW:	DM40_4728
BCEO:	I35_5800
BAM:	Bamb_4154
BAC:	BamMC406_4678
BCT:	GEM_3692
BCED:	DM42_6033
BCEP:	APZ15_29055
BPYR:	ABD05_25895
BCON:	NL30_02460
BUB:	BW23_5558
BDF:	WI26_23065
BLAT:	WK25_26120
BTEI:	WS51_07210
BSEM:	WJ12_29890
BMEC:	WJ16_28455
BSTG:	WT74_28980
BGP:	BGL_1c08090
BGE:	BC1002_6067
BUK:	MYA_4903
BPLA:	bpln_1g07890
PSPW:	BJG93_28690
PVE:	UC34_08230
POX:	MB84_12580
OFO:	BRW83_1280
MFU:	LILAB_28190
MSD:	MYSTI_03759
MYM:	A176_002897
SUR:	STAUR_7751
AGE:	AA314_07683
BVV:	BHK69_26170
BAN:	BA_3891
BAR:	GBAA_3891
BAT:	BAS3604
BAH:	BAMEG_0741
BAI:	BAA_3915
BAX:	H9401_3705
BANT:	A16_38960
BANR:	A16R_39410
BANS:	BAPAT_3727
BANH:	HYU01_19010
BANV:	DJ46_2594
BCE:	BC3761
BCA:	BCE_3793
BCZ:	BCE33L3513
BCR:	BCAH187_A3801
BCB:	BCB4264_A3860
BCU:	BCAH820_3771
BCG:	BCG9842_B1438 BCG9842_B1713
BCQ:	BCQ_3547
BCX:	BCA_3856
BAL:	BACI_c37040(plcA)
BNC:	BCN_3582
BCF:	bcf_18650
BCER:	BCK_16440
BCEF:	BcrFT9_02892
BTK:	BT9727_3501
BTL:	BALH_3388
BTB:	BMB171_C3431
BTT:	HD73_3759 HD73_4047
BTHR:	YBT1520_18545 YBT1520_19995
BTHI:	BTK_18535 BTK_19900
BTC:	CT43_CH3446 CT43_CH3702
BTF:	YBT020_18425
BTM:	MC28_1721 MC28_2930 MC28_C065 MC28_C068 MC28_E065 MC28_E071 MC28_E079 MC28_E138 MC28_E158 MC28_F101
BTG:	BTB_c35790(plcA) BTB_c38340
BTI:	BTG_00580 BTG_01975
BTN:	BTF1_14915 BTF1_16860 BTF1_32876
BTHT:	H175_ch3502 H175_ch3764
BTHU:	YBT1518_19170 YBT1518_20640
BTW:	BF38_4930
BTHY:	AQ980_11120 AQ980_12515
BWE:	BcerKBAB4_2347 BcerKBAB4_3532
BWW:	bwei_1197(plcA2) bwei_2488(plcA)
BTY:	Btoyo_0996
BMYO:	BG05_2262 BG05_3483
BBY:	CY96_17890 CY96_29345
LSP:	Bsph_1112
SAU:	SA0091(plc)
SAV:	SAV0095(plc)
SAW:	SAHV_0094(plc)
SAH:	SaurJH1_0086
SAJ:	SaurJH9_0083
SAM:	MW0070(plc)
SAR:	SAR0105(plc)
SAC:	SACOL0078(plc)
SAX:	USA300HOU_0108(plc)
SAA:	SAUSA300_0099(plc)
SAO:	SAOUHSC_00051
SAE:	NWMN_0041
SAD:	SAAV_0043(plc)
SUU:	M013TW_0088
SUV:	SAVC_00225
SUE:	SAOV_0049(plc)
SUJ:	SAA6159_00079(plc)
SUK:	SAA6008_00080(plc)
SUC:	ECTR2_52
SUT:	SAT0131_00082
SUQ:	HMPREF0772_10395
SUZ:	MS7_0088
SUD:	ST398NM01_0113
SUX:	SAEMRSA15_00670(plc)
SUW:	SATW20_01140(plc)
SUG:	SAPIG0113
SUF:	SARLGA251_00750(plc)
SAUA:	SAAG_00586
SAUE:	RSAU_000049(plc)
SAUN:	SAKOR_00068
SAUS:	SA40_0066(plc)
SAUU:	SA957_0081(plc)
SAUG:	SA268_0078(plc)
SAUZ:	SAZ172_0112(plc)
SAUT:	SAI1T1_2000520(plc)
SAUJ:	SAI2T2_1000520(plc)
SAUK:	SAI3T3_1000520(plc)
SAUQ:	SAI4T8_1000520(plc)
SAUV:	SAI7S6_1000520(plc)
SAUW:	SAI5S5_1000520(plc)
SAUX:	SAI6T6_1000520(plc)
SAUY:	SAI8T7_1000520(plc)
SAB:	SAB0038(plc)
SUY:	SA2981_0095(plc)
SAUB:	C248_0089(plc)
SAUM:	BN843_990
SAUC:	CA347_110
SAUR:	SABB_03691(plc)
SAUI:	AZ30_00505
SAUD:	CH52_05240
SAUF:	X998_0075
SAMS:	NI36_00415
SUH:	SAMSHR1132_00710
LMO:	lmo0201(plcA)
LMF:	LMOf2365_0212(plcA)
LMH:	LMHCC_2442
LMC:	Lm4b_00198(plcA)
LMN:	LM5578_2817(plcA)
LMY:	LM5923_2766(plcA)
LMT:	LMRG_02623
LMG:	LMKG_02774
LMS:	LMLG_2384
LMJ:	LMOG_03054
LMQ:	LMM7_0222(plcA)
LML:	lmo4a_0217(plcA)
LMP:	MUO_01150
LMW:	LMOSLCC2755_0200(plcA)
LMX:	LMOSLCC2372_0202(plcA)
LMZ:	LMOSLCC2482_0201(plcA)
LMON:	LMOSLCC2376_0172(plcA)
LMOC:	LMOSLCC5850_0195(plcA)
LMOS:	LMOSLCC7179_0195
LMOO:	LMOSLCC2378_0214(plcA)
LMOY:	LMOSLCC2479_0201(plcA)
LMOT:	LMOSLCC2540_0204(plcA)
LMOA:	LMOATCC19117_0209(plcA)
LMOL:	LMOL312_0199(plcA)
LMOG:	BN389_02150(plcA)
LMOE:	BN418_0211
LMOB:	BN419_0215
LMOJ:	LM220_06567
LMOZ:	LM1816_04642
LMOD:	LMON_0199(plcA)
LMOW:	AX10_09460
LMOX:	AX24_13615
LMOQ:	LM6179_0491(plcA)
LMR:	LMR479A_0210(plcA)
LMOK:	CQ02_01080
LMV:	Y193_00210
LMOM:	IJ09_09360
LSG:	lse_0182(plcA)
LII:	JL52_01120
LIW:	AX25_01125
LIA:	JL58_01060
LIO:	JL53_01400
EFT:	M395_06895
CBN:	CbC4_5030
CCB:	Clocel_2726
CSB:	CLSA_c09880(plc)
CLT:	CM240_2818
ASF:	SFBM_0755
ASM:	MOUSESFB_0715
ASO:	SFBmNL_00848
ASB:	RATSFB_0638
RAL:	Rumal_3644
BFI:	CIY_07500
DOR:	Desor_4381
NNO:	NONO_c58580
NSR:	NS506_03981
RHW:	BFN03_07585 BFN03_07590
SGR:	SGR_3955
SGB:	WQO_15845
SSX:	SACTE_3590
SVL:	Strvi_2398
SFA:	Sfla_2893
SBH:	SBI_02964
SVE:	SVEN_3910
SALS:	SLNWT_4056
STRP:	F750_3899
SFI:	SFUL_3949
SRC:	M271_13685
SALU:	DC74_6875
SALL:	SAZ_35715
SVT:	SVTN_20440
STRE:	GZL_01891
SLD:	T261_1098
STRM:	M444_16580
SPRI:	SPRI_4007
SCZ:	ABE83_16490
SLC:	SL103_23150
SCLF:	BB341_12700
SNR:	SNOUR_08420
SNW:	BBN63_18485
FAL:	FRAAL3352
KPHY:	AOZ06_27935
ACTN:	L083_6541
CAI:	Caci_6736
SNA:	Snas_3757
MPK:	VL20_4487
BFR:	BF1750
BFG:	BF638R_1749
BFB:	VU15_07445
BHL:	Bache_0066
CPI:	Cpin_5471
PCM:	AY601_4351
PSTY:	BFS30_17445
DFE:	Dfer_0819
FCO:	FCOL_09560
EAO:	BD94_2786
EMN:	M876_10895
ELB:	VO54_03886(plc)
EEN:	BBD30_12930
EMG:	BBD33_09105
CHZ:	CHSO_1681 CHSO_4603(plc)
CGN:	OK18_05910
CIH:	ATE47_14310
CIO:	CEQ15_16315

» show all

Reference

PMID:3194218

Authors

Henner DJ, Yang M, Chen E, Hellmiss R, Rodriguez H, Low MG

Title

Sequence of the Bacillus thuringiensis phosphatidylinositol specific phospholipase C.

Journal

Nucleic Acids Res 16:10383 (1988)
DOI:10.1093/nar/16.21.10383

Sequence

[btk:BT9727_3501]

All links

Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (2109)   
   KEGG GENES (500)   
   KEGG MGENES (1337)   
   RefGene (222)   
   EGENES (16)   
   OC (34)   
Protein sequence (285)   
   UniProt (282)   
   SWISS-PROT (3)   
Literature (1)   
   PubMed (1)   
All databases (2404)   

Download RDF

ENZYME: 4.6.1.13

Entry

EC 4.6.1.13 Enzyme

Name

phosphatidylinositol diacylglycerol-lyase;
monophosphatidylinositol phosphodiesterase;
phosphatidylinositol phospholipase C;
1-phosphatidylinositol phosphodiesterase;
1-phosphatidyl-D-myo-inositol inositolphosphohydrolase (cyclic-phosphate-forming);
1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming)

Class

Lyases;
Phosphorus-oxygen lyases;
Phosphorus-oxygen lyases (only sub-subclass identified to date)

Sysname

1-phosphatidyl-1D-myo-inositol 1,2-diacyl-sn-glycerol-lyase (1D-myo-inositol-1,2-cyclic-phosphate-forming)

Reaction(IUBMB)

1-phosphatidyl-1D-myo-inositol = 1D-myo-inositol 1,2-cyclic phosphate + 1,2-diacyl-sn-glycerol [RN:R03364]

Reaction(KEGG)

R03364;
(other) R03332

Substrate

1-phosphatidyl-1D-myo-inositol [CPD:C01194]

Product

1D-myo-inositol 1,2-cyclic phosphate [CPD:C04299];
1,2-diacyl-sn-glycerol [CPD:C00641]

Comment

This enzyme is bacterial. Activity is also found in animals, but this activity is due to the presence of EC 3.1.4.11, phosphoinositide phospholipase C.

History

EC 4.6.1.13 created 1972 as EC 3.1.4.10, modified 1976, transferred 2002 to EC 4.6.1.13

Pathway

ec00562

Inositol phosphate metabolism

Orthology

K01771

1-phosphatidylinositol phosphodiesterase

Genes

OAA:	107547964
GGA:	101751271
MGP:	104912324
CJO:	107317149
ACYG:	106041539
FAB:	107603775
PHI:	106628453
FPG:	106112280
FCH:	106631759
CLV:	106145769
ACS:	100567546
PBI:	103068284
GJA:	107114885 107114896
XLA:	108710460
XTR:	100494672
NPR:	108790680
DRE:	100000275 100006223(si:dkey-266f7.9)
SRX:	107750812 107756887
SANH:	107688224 107693279
SGH:	107589506 107592133 107592465
IPU:	108256182
TRU:	101062629
TNG:	GSTEN00032541G001
LCO:	104927567 104932167
NCC:	104964990 104967986
MZE:	101464692 101486202
OLA:	101162017
XMA:	102223877
CSEM:	103394551
LCF:	108879457 108899480
SASA:	106570214
ELS:	105012651 105014773
SFM:	108930395 108932007 108932008 108938283
LCM:	102353481 102357360 106704972
SKO:	100378443 100378594 102805589
TUT:	107363869
LGI:	LOTGIDRAFT_199696
OBI:	106880796 106880803
LJA:	Lj1g3v3343840.1(Lj1g3v3343840.1)
CCP:	CHC_T00007789001
AGO:	AGOS_AFR607C
ERC:	Ecym_2326
LTH:	KLTH0H11308g
TBL:	TBLA_0G03650(TBLA0G03650)
PPA:	PAS_chr4_0907
DHA:	DEHA2G04180g
PIC:	PICST_70308
PGU:	PGUG_02986
SPAA:	SPAPADRAFT_60801
LEL:	LELG_01298
CAL:	CAALFM_C202600CA(FGR22) CAALFM_C203040WA(PLC2)
CTP:	CTRG_01321 CTRG_01371
COT:	CORT_0A10910
CDU:	CD36_17390(PLC22) CD36_17810
CTEN:	CANTEDRAFT_112125
YLI:	YALI0D10813g
CLU:	CLUG_00951
CAUR:	QG37_01069
NCR:	NCU08982 NCU09135
NTE:	NEUTE1DRAFT149986(NEUTE1DRAFT_149986)
SMP:	SMAC_01937 SMAC_04631
PAN:	PODANSg09605
TTT:	THITE_2010991
MTM:	MYCTH_2294314
CTHR:	CTHT_0073210
MGR:	MGG_04834
TMN:	UCRPA7_1358 UCRPA7_7184 UCRPA7_7913
FGR:	FGSG_00423 FGSG_05655
FPU:	FPSE_00086 FPSE_06249 FPSE_11073
FVR:	FVEG_00884 FVEG_06828 FVEG_08738
FOX:	FOXG_00628 FOXG_09227
NHE:	NECHADRAFT_57455 NECHADRAFT_70960
TRE:	TRIREDRAFT_111102 TRIREDRAFT_57975
MAW:	MAC_02826 MAC_03182 MAC_05413
MAJ:	MAA_04277 MAA_04887 MAA_10423
CMT:	CCM_02309 CCM_09301
VAL:	VDBG_01003 VDBG_06112
VDA:	VDAG_00614 VDAG_03270
CFJ:	CFIO01_03094 CFIO01_12060
ELA:	UCREL1_1181
PFY:	PFICI_01340
SSL:	SS1G_06734 SS1G_12385
BFU:	BC1G_01342 BC1G_14570
MBE:	MBM_05780
PSCO:	LY89DRAFT_648735 LY89DRAFT_690521 LY89DRAFT_691271 LY89DRAFT_708673
GLZ:	GLAREA_11821
ANI:	AN3636.2
AFM:	AFUA_4G12000
AOR:	AOR_1_1798154(AO090003001009)
ANG:	ANI_1_2710014(An01g07280)
AFV:	AFLA_028080
ACT:	ACLA_051030
NFI:	NFIA_104240
PCS:	Pc22g05150
PDP:	PDIP_86100
CIM:	CIMG_01631
CPW:	CPC735_048450
PBL:	PAAG_02760
PBN:	PADG_01787
URE:	UREG_05354
ABE:	ARB_00415
TVE:	TRV_02704
AJE:	HCAG_01498
PNO:	SNOG_06918
PTE:	PTT_15969
BZE:	COCCADRAFT_29910
BSC:	COCSADRAFT_28875
BOR:	COCMIDRAFT_92880
ZTR:	MYCGRDRAFT_107761 MYCGRDRAFT_109874 MYCGRDRAFT_98925
PFJ:	MYCFIDRAFT_189591 MYCFIDRAFT_29247
BCOM:	BAUCODRAFT_144753 BAUCODRAFT_71222
NPA:	UCRNP2_1182
TML:	GSTUM_00011434001
CGI:	CGB_C8350C
TMS:	TREMEDRAFT_25826
TVS:	TRAVEDRAFT_28301
DSQ:	DICSQDRAFT_57461
PCO:	PHACADRAFT_256922
SHS:	STEHIDRAFT_102395 STEHIDRAFT_52122
HIR:	HETIRDRAFT_311254
PSQ:	PUNSTDRAFT_114420
ADL:	AURDEDRAFT_112159 AURDEDRAFT_113803
FME:	FOMMEDRAFT_132498
GTR:	GLOTRDRAFT_137236
LBC:	LACBIDRAFT_308269 LACBIDRAFT_315813 LACBIDRAFT_318365 LACBIDRAFT_335698
MPR:	MPER_09363
MRR:	Moror_14864 Moror_4204
CCI:	CC1G_10832 CC1G_13081
SCM:	SCHCODRAFT_106139 SCHCODRAFT_51562
ABP:	AGABI1DRAFT104838(AGABI1DRAFT_104838) AGABI1DRAFT121976(AGABI1DRAFT_121976)
ABV:	AGABI2DRAFT200290(AGABI2DRAFT_200290) AGABI2DRAFT210674(AGABI2DRAFT_210674)
CPUT:	CONPUDRAFT_48596
SLA:	SERLADRAFT_441016
UMA:	UMAG_04644
PFP:	PFL1_04542
PGR:	PGTG_06638 PGTG_22509
MLR:	MELLADRAFT_116429 MELLADRAFT_84419
TET:	TTHERM_000426139 TTHERM_00426140
TVA:	TVAG_301070 TVAG_372910
YEP:	YE105_C2085
YEY:	Y11_08861
YEL:	LC20_02835(plc) LC20_02836(plc)
YET:	CH48_3722
YAL:	AT01_349
YFR:	AW19_1307
YKR:	CH54_355
YRU:	BD65_1648 BD65_1649
SOD:	Sant_P0333
EPY:	EpC_18250
EPR:	EPYR_01964(plc)
EAM:	EAMY_1766(plc)
EAY:	EAM_1731
ERJ:	EJP617_29000
MMK:	MU9_1927
HSO:	HS_1585
HSM:	HSM_0426
GAN:	UMN179_01455
GHO:	AL542_15205
PMAN:	OU5_0316
PRR:	AT705_21210
MVS:	MVIS_0305
MDH:	AYM39_00650 AYM39_02300
OAI:	OLEAN_C15740(plcA)
GSN:	YC6258_03989
BVI:	Bcep1808_5289
BVE:	AK36_3592
BUR:	Bcep18194_B0943
BCN:	Bcen_3596
BCH:	Bcen2424_4771
BCM:	Bcenmc03_5512
BCJ:	BCAM1969
BCEW:	DM40_4728
BCEO:	I35_5800
BAM:	Bamb_4154
BAC:	BamMC406_4678
BCT:	GEM_3692
BCED:	DM42_6033
BCEP:	APZ15_29055
BPYR:	ABD05_25895
BCON:	NL30_02460
BUB:	BW23_5558
BDF:	WI26_23065
BLAT:	WK25_26120
BTEI:	WS51_07210
BSEM:	WJ12_29890
BMEC:	WJ16_28455
BSTG:	WT74_28980
BGP:	BGL_1c08090
BGE:	BC1002_6067
BUK:	MYA_4903
BPLA:	bpln_1g07890
PSPW:	BJG93_28690
PVE:	UC34_08230
POX:	MB84_12580
OFO:	BRW83_1280
MFU:	LILAB_28190
MSD:	MYSTI_03759
MYM:	A176_002897
SUR:	STAUR_7751
AGE:	AA314_07683
BVV:	BHK69_26170
BAN:	BA_3891
BAR:	GBAA_3891
BAT:	BAS3604
BAH:	BAMEG_0741
BAI:	BAA_3915
BAX:	H9401_3705
BANT:	A16_38960
BANR:	A16R_39410
BANS:	BAPAT_3727
BANH:	HYU01_19010
BANV:	DJ46_2594
BCE:	BC3761
BCA:	BCE_3793
BCZ:	BCE33L3513
BCR:	BCAH187_A3801
BCB:	BCB4264_A3860
BCU:	BCAH820_3771
BCG:	BCG9842_B1438 BCG9842_B1713
BCQ:	BCQ_3547
BCX:	BCA_3856
BAL:	BACI_c37040(plcA)
BNC:	BCN_3582
BCF:	bcf_18650
BCER:	BCK_16440
BCEF:	BcrFT9_02892
BTK:	BT9727_3501
BTL:	BALH_3388
BTB:	BMB171_C3431
BTT:	HD73_3759 HD73_4047
BTHR:	YBT1520_18545 YBT1520_19995
BTHI:	BTK_18535 BTK_19900
BTC:	CT43_CH3446 CT43_CH3702
BTF:	YBT020_18425
BTM:	MC28_1721 MC28_2930 MC28_C065 MC28_C068 MC28_E065 MC28_E071 MC28_E079 MC28_E138 MC28_E158 MC28_F101
BTG:	BTB_c35790(plcA) BTB_c38340
BTI:	BTG_00580 BTG_01975
BTN:	BTF1_14915 BTF1_16860 BTF1_32876
BTHT:	H175_ch3502 H175_ch3764
BTHU:	YBT1518_19170 YBT1518_20640
BTW:	BF38_4930
BTHY:	AQ980_11120 AQ980_12515
BWE:	BcerKBAB4_2347 BcerKBAB4_3532
BWW:	bwei_1197(plcA2) bwei_2488(plcA)
BTY:	Btoyo_0996
BMYO:	BG05_2262 BG05_3483
BBY:	CY96_17890 CY96_29345
LSP:	Bsph_1112
SAU:	SA0091(plc)
SAV:	SAV0095(plc)
SAW:	SAHV_0094(plc)
SAH:	SaurJH1_0086
SAJ:	SaurJH9_0083
SAM:	MW0070(plc)
SAR:	SAR0105(plc)
SAC:	SACOL0078(plc)
SAX:	USA300HOU_0108(plc)
SAA:	SAUSA300_0099(plc)
SAO:	SAOUHSC_00051
SAE:	NWMN_0041
SAD:	SAAV_0043(plc)
SUU:	M013TW_0088
SUV:	SAVC_00225
SUE:	SAOV_0049(plc)
SUJ:	SAA6159_00079(plc)
SUK:	SAA6008_00080(plc)
SUC:	ECTR2_52
SUT:	SAT0131_00082
SUQ:	HMPREF0772_10395
SUZ:	MS7_0088
SUD:	ST398NM01_0113
SUX:	SAEMRSA15_00670(plc)
SUW:	SATW20_01140(plc)
SUG:	SAPIG0113
SUF:	SARLGA251_00750(plc)
SAUA:	SAAG_00586
SAUE:	RSAU_000049(plc)
SAUN:	SAKOR_00068
SAUS:	SA40_0066(plc)
SAUU:	SA957_0081(plc)
SAUG:	SA268_0078(plc)
SAUZ:	SAZ172_0112(plc)
SAUT:	SAI1T1_2000520(plc)
SAUJ:	SAI2T2_1000520(plc)
SAUK:	SAI3T3_1000520(plc)
SAUQ:	SAI4T8_1000520(plc)
SAUV:	SAI7S6_1000520(plc)
SAUW:	SAI5S5_1000520(plc)
SAUX:	SAI6T6_1000520(plc)
SAUY:	SAI8T7_1000520(plc)
SAB:	SAB0038(plc)
SUY:	SA2981_0095(plc)
SAUB:	C248_0089(plc)
SAUM:	BN843_990
SAUC:	CA347_110
SAUR:	SABB_03691(plc)
SAUI:	AZ30_00505
SAUD:	CH52_05240
SAUF:	X998_0075
SAMS:	NI36_00415
SUH:	SAMSHR1132_00710
LMO:	lmo0201(plcA)
LMF:	LMOf2365_0212(plcA)
LMH:	LMHCC_2442
LMC:	Lm4b_00198(plcA)
LMN:	LM5578_2817(plcA)
LMY:	LM5923_2766(plcA)
LMT:	LMRG_02623
LMG:	LMKG_02774
LMS:	LMLG_2384
LMJ:	LMOG_03054
LMQ:	LMM7_0222(plcA)
LML:	lmo4a_0217(plcA)
LMP:	MUO_01150
LMW:	LMOSLCC2755_0200(plcA)
LMX:	LMOSLCC2372_0202(plcA)
LMZ:	LMOSLCC2482_0201(plcA)
LMON:	LMOSLCC2376_0172(plcA)
LMOC:	LMOSLCC5850_0195(plcA)
LMOS:	LMOSLCC7179_0195
LMOO:	LMOSLCC2378_0214(plcA)
LMOY:	LMOSLCC2479_0201(plcA)
LMOT:	LMOSLCC2540_0204(plcA)
LMOA:	LMOATCC19117_0209(plcA)
LMOL:	LMOL312_0199(plcA)
LMOG:	BN389_02150(plcA)
LMOE:	BN418_0211
LMOB:	BN419_0215
LMOJ:	LM220_06567
LMOZ:	LM1816_04642
LMOD:	LMON_0199(plcA)
LMOW:	AX10_09460
LMOX:	AX24_13615
LMOQ:	LM6179_0491(plcA)
LMR:	LMR479A_0210(plcA)
LMOK:	CQ02_01080
LMV:	Y193_00210
LMOM:	IJ09_09360
LSG:	lse_0182(plcA)
LII:	JL52_01120
LIW:	AX25_01125
LIA:	JL58_01060
LIO:	JL53_01400
EFT:	M395_06895
CBN:	CbC4_5030
CCB:	Clocel_2726
CSB:	CLSA_c09880(plc)
CLT:	CM240_2818
ASF:	SFBM_0755
ASM:	MOUSESFB_0715
ASO:	SFBmNL_00848
ASB:	RATSFB_0638
RAL:	Rumal_3644
BFI:	CIY_07500
DOR:	Desor_4381
NNO:	NONO_c58580
NSR:	NS506_03981
RHW:	BFN03_07585 BFN03_07590
SGR:	SGR_3955
SGB:	WQO_15845
SSX:	SACTE_3590
SVL:	Strvi_2398
SFA:	Sfla_2893
SBH:	SBI_02964
SVE:	SVEN_3910
SALS:	SLNWT_4056
STRP:	F750_3899
SFI:	SFUL_3949
SRC:	M271_13685
SALU:	DC74_6875
SALL:	SAZ_35715
SVT:	SVTN_20440
STRE:	GZL_01891
SLD:	T261_1098
STRM:	M444_16580
SPRI:	SPRI_4007
SCZ:	ABE83_16490
SLC:	SL103_23150
SCLF:	BB341_12700
SNR:	SNOUR_08420
SNW:	BBN63_18485
FAL:	FRAAL3352
KPHY:	AOZ06_27935
ACTN:	L083_6541
CAI:	Caci_6736
SNA:	Snas_3757
MPK:	VL20_4487
BFR:	BF1750
BFG:	BF638R_1749
BFB:	VU15_07445
BHL:	Bache_0066
CPI:	Cpin_5471
PCM:	AY601_4351
PSTY:	BFS30_17445
DFE:	Dfer_0819
FCO:	FCOL_09560
EAO:	BD94_2786
EMN:	M876_10895
ELB:	VO54_03886(plc)
EEN:	BBD30_12930
EMG:	BBD33_09105
CHZ:	CHSO_1681 CHSO_4603(plc)
CGN:	OK18_05910
CIH:	ATE47_14310
CIO:	CEQ15_16315

» show all

Reference

1 [PMID:4377210]

Authors

Allan D, Michell RH.

Title

Phosphatidylinositol cleavage catalysed by the soluble fraction from lymphocytes. Activity at pH5.5 and pH7.0.

Journal

Biochem. J. 142 (1974) 591-7.

Reference

2 [PMID:4294905]

Authors

Friedel RO, Brown JD, Durell.

Title

Monophosphatidyl inositol inositolphosphohydrolase in guinea-pig brain.

Journal

Biochim. Biophys. Acta. 144 (1967) 684-6.

Reference

3 [PMID:6297738]

Authors

Irvine RF.

Title

The enzymology of stimulated inositol lipid turnover.

Journal

Cell. Calcium. 3 (1982) 295-309.

Reference

4 [PMID:236918]

Authors

Michell RH, Allan D.

Title

Inositol cyclis phosphate as a product of phosphatidylinositol breakdown by phospholipase C (Bacillus cereus).

Journal

FEBS. Lett. 53 (1975) 302-4.

Reference

5 [PMID:588258]

Authors

Low MG, Finean JB.

Title

Release of alkaline phosphatase from membranes by a phosphatidylinositol-specific phospholipase C.

Journal

Biochem. J. 167 (1977) 281-4.

Reference

6 [PMID:3194218]

Authors

Henner DJ, Yang M, Chen E, Hellmiss R, Rodriguez H, Low MG.

Title

Sequence of the Bacillus thuringiensis phosphatidylinositol specific phospholipase C.

Journal

Nucleic. Acids. Res. 16 (1988) 10383.

Sequence

[btk:BT9727_3501]

Other DBs

ExplorEnz - The Enzyme Database:

4.6.1.13

IUBMB Enzyme Nomenclature:

4.6.1.13

ExPASy - ENZYME nomenclature database:

4.6.1.13

BRENDA, the Enzyme Database:

4.6.1.13

CAS:

37288-19-0

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (5)   
   KEGG REACTION (2)   
   KEGG RCLASS (3)   
Gene (2076)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (500)   
   KEGG MGENES (1337)   
   RefGene (222)   
   EGENES (16)   
Protein sequence (285)   
   UniProt (236)   
   SWISS-PROT (5)   
   RefSeq(pep) (13)   
   PDBSTR (24)   
   PMD (7)   
DNA sequence (383)   
   RefSeq(nuc) (21)   
   GenBank (185)   
   EMBL (177)   
3D Structure (18)   
   PDB (18)   
All databases (2774)   

Download RDF

REACTION: R03332

Entry

R03332 Reaction

Name

1-Phosphatidyl-D-myo-inositol inositolphosphohydrolase

Definition

1-Phosphatidyl-D-myo-inositol + H2O <=> Inositol 1-phosphate + 1,2-Diacyl-sn-glycerol

Equation

C01194 + C00001 <=> C01177 + C00641

Reaction class

RC00017	C00641_C01194
RC00425	C01177_C01194

Enzyme

3.1.4.3 3.1.4.11 4.6.1.13

Pathway

rn00562

Inositol phosphate metabolism

Orthology

K01114	phospholipase C [EC:3.1.4.3]
K01116	phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K01771	1-phosphatidylinositol phosphodiesterase [EC:4.6.1.13]
K05857	phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05858	phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05859	phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K05860	phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K05861	phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
K16619	phospholipase C / alpha-toxin [EC:3.1.4.3]
K19006	phosphatidylinositol phospholipase C, eta [EC:3.1.4.11]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (5)   
   KEGG ENZYME (3)   
   KEGG RCLASS (2)   
Gene (4901)   
   KEGG ORTHOLOGY (10)   
   KEGG GENES (4891)   
All databases (4915)   

Download RDF

DBGET integrated database retrieval system