KEGG   ORTHOLOGY: K03868Help
Entry
K03868                      KO                                     

Name
RBX1, ROC1
Definition
RING-box protein 1
Pathway
Nucleotide excision repair
HIF-1 signaling pathway
Cell cycle
Cell cycle - yeast
Oocyte meiosis
Ubiquitin mediated proteolysis
Protein processing in endoplasmic reticulum
Wnt signaling pathway
TGF-beta signaling pathway
Circadian rhythm
Pathways in cancer
Renal cell carcinoma
Module
M00379  
SCF-MET30 complex
M00380  
SCF-BTRC complex
M00381  
SCF-SKP2 complex
M00382  
SCF-FBS complex
M00383  
ECV complex
M00384  
Cul3-SPOP complex
M00385  
Cul4-DDB1-DDB2 complex
M00386  
Cul4-DDB1-CSA complex
M00387  
SCF-FBW7 complex
M00407  
SCF-CDC4 complex
M00411  
SCF-GRR1 complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K03868  RBX1, ROC1; RING-box protein 1
   04120 Ubiquitin mediated proteolysis
    K03868  RBX1, ROC1; RING-box protein 1
  Replication and repair
   03420 Nucleotide excision repair
    K03868  RBX1, ROC1; RING-box protein 1
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    K03868  RBX1, ROC1; RING-box protein 1
   04350 TGF-beta signaling pathway
    K03868  RBX1, ROC1; RING-box protein 1
   04066 HIF-1 signaling pathway
    K03868  RBX1, ROC1; RING-box protein 1
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K03868  RBX1, ROC1; RING-box protein 1
   04111 Cell cycle - yeast
    K03868  RBX1, ROC1; RING-box protein 1
   04114 Oocyte meiosis
    K03868  RBX1, ROC1; RING-box protein 1
 Organismal Systems
  Environmental adaptation
   04710 Circadian rhythm
    K03868  RBX1, ROC1; RING-box protein 1
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K03868  RBX1, ROC1; RING-box protein 1
   05211 Renal cell carcinoma
    K03868  RBX1, ROC1; RING-box protein 1
KEGG pathway modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Ubiquitin system
    M00379  SCF-MET30 complex [BR:ko04121]
     K03868  RBX1, ROC1; RING-box protein 1
    M00380  SCF-BTRC complex [BR:ko04121]
     K03868  RBX1, ROC1; RING-box protein 1
    M00381  SCF-SKP2 complex [BR:ko04121]
     K03868  RBX1, ROC1; RING-box protein 1
    M00382  SCF-FBS complex [BR:ko04121]
     K03868  RBX1, ROC1; RING-box protein 1
    M00407  SCF-CDC4 complex [BR:ko04121]
     K03868  RBX1, ROC1; RING-box protein 1
    M00411  SCF-GRR1 complex [BR:ko04121]
     K03868  RBX1, ROC1; RING-box protein 1
    M00383  ECV complex [BR:ko04121]
     K03868  RBX1, ROC1; RING-box protein 1
    M00384  Cul3-SPOP complex [BR:ko04121]
     K03868  RBX1, ROC1; RING-box protein 1
    M00385  Cul4-DDB1-DDB2 complex [BR:ko04121 ko03400]
     K03868  RBX1, ROC1; RING-box protein 1
    M00386  Cul4-DDB1-CSA complex [BR:ko04121 ko03400]
     K03868  RBX1, ROC1; RING-box protein 1
    M00387  SCF-FBW7 complex [BR:ko04121]
     K03868  RBX1, ROC1; RING-box protein 1
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  UBL E3 ligases
   K03868  RBX1, ROC1; RING-box protein 1
  multi subunit Ring-finger type E3
   SCF complex
    Ring finger protein
     K03868  RBX1, ROC1; RING-box protein 1
   ECV complex
    Ring finger protein
     K03868  RBX1, ROC1; RING-box protein 1
   Cul3 complex
    Ring finger protein
     K03868  RBX1, ROC1; RING-box protein 1
   Cul4 complex
    Ring finger protein
     K03868  RBX1, ROC1; RING-box protein 1
   Cul7 complex
    Ring finger protein
     K03868  RBX1, ROC1; RING-box protein 1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      K03868  RBX1, ROC1; RING-box protein 1
    TCR (transcription coupled repair) factors
     Cul4-CSA complex
      K03868  RBX1, ROC1; RING-box protein 1
BRITE hierarchy
Genes
HSA: 
9978(RBX1)
PTR: 
458860(RBX1)
PPS: 
GGO: 
101151577(RBX1)
PON: 
100441665(RBX1)
MCC: 
MCF: 
102132483(RBX1)
MMU: 
100043674(Gm9840) 56438(Rbx1)
RNO: 
300084(Rbx1)
CGE: 
HGL: 
101712475(Rbx1)
TUP: 
102468598(RBX1)
CFA: 
474494(RBX1)
AML: 
FCA: 
101087758(RBX1)
PTG: 
102955881(RBX1)
BTA: 
BOM: 
102272719(RBX1)
PHD: 
CHX: 
CFR: 
102515877(RBX1)
ECB: 
100055581(RBX1)
MYB: 
102260998(RBX1)
MYD: 
102760790(RBX1)
PALE: 
102893437(RBX1)
MDO: 
SHR: 
100918404(RBX1)
OAA: 
GGA: 
418001(RBX1)
MGP: 
TGU: 
PHI: 
102102832(RBX1)
APLA: 
101796040(RBX1)
CLV: 
102095842(RBX1)
ASN: 
102372162(RBX1)
PSS: 
102451113(RBX1)
CMY: 
102943754(RBX1)
ACS: 
XTR: 
100379935(rbx1)
DRE: 
449846(rbx1)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102352187(RBX1)
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
408691(Roc1a)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG19342(Cbr-rbx-1)
BMY: 
LOA: 
NVE: 
HMG: 
TAD: 
AQU: 
ATH: 
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
MTR: 
CAM: 
FVE: 
CSV: 
RCU: 
POP: 
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os01t0106800-01(Os01g0106800) Os02t0708300-01(Os02g0708300)
OBR: 
BDI: 
SBI: 
SORBI_03g008660(SORBIDRAFT_03g008660) SORBI_04g030370(SORBIDRAFT_04g030370)
ZMA: 
100192928(Rbx1)
SITA: 
ATR: 
s00024p00244120(AMTR_s00024p00244120)
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
OTA: 
MIS: 
MPP: 
CSL: 
CME: 
GSL: 
CCP: 
SCE: 
YOL133W(HRT1)
AGO: 
ERC: 
KLA: 
LTH: 
PPA: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0C04480(NCAS0C04480)
NDI: 
NDAI_0G03860(NDAI0G03860)
TPF: 
TPHA_0P01470(TPHA0P01470)
TBL: 
TBLA_0B08710(TBLA0B08710)
TDL: 
TDEL_0A00470(TDEL0A00470)
KAF: 
KAFR_0C01780(KAFR0C01780)
DHA: 
PIC: 
LEL: 
CTP: 
CDU: 
COT: 
YLI: 
CLU: 
SMP: 
PAN: 
MTM: 
MGR: 
FGR: 
NHE: 
TRE: 
VAL: 
SSL: 
BFU: 
ANI: 
NFI: 
AFM: 
AOR: 
AOR_1_1150184(AO090009000684)
ANG: 
ANI_1_294154(An17g02100)
AFV: 
ACT: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
ZTR: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
LBC: 
CCI: 
SCM: 
UMA: 
MGL: 
PGR: 
ECU: 
EIN: 
EHE: 
NCE: 
MBR: 
DDI: 
DPP: 
EHI: 
EHI_151630(2.t00108)
EDI: 
ACAN: 
PFA: 
PFD: 
PFH: 
PYO: 
PCB: 
PBE: 
PKN: 
PVX: 
PCY: 
TAN: 
TPV: 
BBO: 
BBOV_III007590(17.m07664)
CPV: 
CHO: 
TGO: 
TET: 
PTM: 
PTI: 
TPS: 
PIF: 
NGD: 
EHX: 
GTT: 
TBR: 
TCR: 
LMA: 
LIF: 
LDO: 
LMI: 
LBZ: 
NGR: 
TVA: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Petroski MD, Deshaies RJ.
  Title
Function and regulation of cullin-RING ubiquitin ligases.
  Journal
Nat Rev Mol Cell Biol 6:9-20 (2005)
Reference
  Authors
Jin J, Cardozo T, Lovering RC, Elledge SJ, Pagano M, Harper JW.
  Title
Systematic analysis and nomenclature of mammalian F-box proteins.
  Journal
Genes Dev 18:2573-80 (2004)

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