KEGG ORTHOLOGY: K05783

ORTHOLOGY: K05783

Entry

K05783 KO

Name

benD-xylL

Definition

dihydroxycyclohexadiene carboxylate dehydrogenase [EC:1.3.1.25 1.3.1.-]

Pathway

ko00362	Benzoate degradation
ko00364	Fluorobenzoate degradation
ko00622	Xylene degradation
ko01220	Degradation of aromatic compounds

Module

M00551

Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Overview
   01220 Degradation of aromatic compounds
    K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
  Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
   00364 Fluorobenzoate degradation
    K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
   00622 Xylene degradation
    K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
KEGG modules [BR:ko00002]
Pathway module
  Secondary metabolism
   Aromatics degradation
    M00551  Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol
     K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.25  1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
     K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase
    1.3.1.-
     K05783  benD-xylL; dihydroxycyclohexadiene carboxylate dehydrogenase

Other DBs

RN:

R00813 R05292 R05293 R05309 R05314 R08111 R08112 R08113

COG:

COG1028

GO:

0047116

Genes

EFE:	EFER_1485(benD)
KPN:	KPN_01869
KPU:	KP1_2934
KPM:	KPHS_28390
KPP:	A79E_2376
KPK:	A593_24210(benD)
KPH:	KPNIH24_14210(benD)
KPZ:	KPNIH27_13570(benD)
KPV:	KPNIH29_14240(benD)
KPW:	KPNIH30_14505(benD)
KPY:	KPNIH31_13520(benD)
KPG:	KPNIH32_14400(benD)
KPC:	KPNIH10_14040(benD)
KPQ:	KPR0928_14020(benD)
KPT:	VK055_0615
KPE:	KPK_2488(cbeD)
KPO:	KPN2242_12265(benD)
KPR:	KPR_2933(benD)
KPJ:	N559_2421
KPI:	D364_09585(benD)
KPA:	KPNJ1_02608
KPS:	KPNJ2_02563
KPX:	PMK1_04210(lvr)
KPB:	FH42_05420(benD)
KPNE:	KU54_012115(benD)
KPNU:	LI86_12050(benD)
KVA:	Kvar_2435
KVD:	KR75_22145(benD)
KVQ:	SP68_02890(benD)
KOC:	AB185_22235(benD)
KQU:	AVR78_18380(benD)
EAE:	EAE_19880(benD)
EAR:	CCG29904
CAF:	AL524_15085(benD)
EBT:	EBL_c18160
ROR:	RORB6_06755(benD)
RON:	TE10_13830(benD)
PGE:	LG71_16210(benD)
EBF:	D782_2133
SMAF:	D781_2850
SMW:	SMWW4_v1c30600
SRZ:	AXX16_2219
XSA:	SB85_10140(benD)
PSD:	DSC_14910(benD)
VNA:	PN96_18365(benD)
VEJ:	VEJY3_17926(benD)
PAE:	PA2515(xylL)
PAEV:	N297_2586
PAEI:	N296_2586
PAU:	PA14_32130(xylL)
PAP:	PSPA7_2722(xylL)
PAG:	PLES_27801(xylL)
PAF:	PAM18_2524(benD)
PNC:	NCGM2_3520(benD)
PAEB:	NCGM1900_4012(benD)
PDK:	PADK2_12670(benD)
PSG:	G655_12450(benD)
PRP:	M062_13075(benD)
PAEP:	PA1S_13070(benD)
PAER:	PA1R_gp0309
PAEM:	U769_12650(benD)
PAEL:	T223_14270(benD)
PAES:	SCV20265_2794
PAEU:	BN889_02739(benD)
PAEG:	AI22_20850(benD)
PAEC:	M802_2583
PAEO:	M801_2451
PMK:	MDS_4167
PRE:	PCA10_30910(benD)
PPSE:	BN5_3608(benD)
PCQ:	PcP3B5_23360(lvr)
PPU:	PP_3164(benD)
PPF:	Pput_2551
PPG:	PputGB1_2685
PPW:	PputW619_2707
PPT:	PPS_2762
PPB:	PPUBIRD1_2569(benD)
PPI:	YSA_10652
PPX:	T1E_1059(benD)
PPUH:	B479_13460(benD)
PPUT:	L483_17645(benD)
PPUN:	PP4_25400(benD) PP4_48180(benD)
PPUD:	DW66_3021
PFV:	Psefu_2026
PMON:	X969_13160(benD)
PMOT:	X970_12805(benD)
PPJ:	RK21_01914
PFL:	PFL_3855(xylL)
PPRC:	PFLCHA0_c39130(xylL)
PPRO:	PPC_3951(benD)
PFO:	Pfl01_2324 Pfl01_2965(benD)
PFE:	PSF113_2894(benD)
PFN:	HZ99_02920(benD)
PFX:	A7318_13915(benD)
PMAN:	OU5_6167(xylL)
PAZO:	AYR47_21845(benD)
PEN:	PSEEN3140(benD)
PSA:	PST_1670(benD)
PSR:	PSTAA_1698(benD)
PSC:	A458_09170(benD)
PSJ:	PSJM300_08880(benD)
PSH:	Psest_2696
PSTU:	UIB01_13630(benD)
PBM:	CL52_07430(benD)
PBA:	PSEBR_a2882
PPUU:	PputUW4_03254(xylL)
PDR:	H681_11365(benD)
PSV:	PVLB_12230(benD)
PKC:	PKB_2103(xylL)
PCH:	EY04_20395(benD)
PCZ:	PCL1606_21670
PCP:	JM49_10825(benD)
PFZ:	AV641_09800(benD)
PALK:	PSAKL28_52390
PSES:	PSCI_4806(benD)
PSEM:	TO66_21090(benD)
PPSY:	AOC04_06645(benD)
PSOS:	POS17_3976(benD)
PFK:	PFAS1_22860(benD)
AVN:	Avin_08620(benD)
AVL:	AvCA_08620(benD)
AVD:	AvCA6_08620(benD)
ACX:	Achr_32810(benD)
PCR:	Pcryo_1264
PSO:	PSYCG_06665(benD)
PALI:	A3K91_1588
PSPG:	AK823_04985
PSYG:	AK825_05000
ACB:	A1S_1212
ABY:	ABAYE2558(benD)
ABC:	ACICU_01189
ABN:	AB57_1347
ABB:	ABBFA_002367
ABX:	ABK1_1644
ABZ:	ABZJ_01348
ABR:	ABTJ_02517
ABD:	ABTW07_1376
ABH:	M3Q_1568
ABAD:	ABD1_12210(benD)
ABJ:	BJAB07104_01359
ABAB:	BJAB0715_01371
ABAJ:	BJAB0868_01307
ABAZ:	P795_11430
ABK:	LX00_05835
ABAU:	IX87_04590
ABAA:	IX88_08130
ABW:	BL01_13775
ABAL:	ABLAC_20300
ACC:	BDGL_000463(benD)
ANO:	RR32_12270
ACD:	AOLE_13350(benD)
ACI:	ACIAD1439(benD)
ATT:	AMQ28_00600
AEI:	AOY20_11285
AJO:	RZ95_08915
ACW:	A0J50_11650
ACV:	AMD27_07845
AJN:	BVL33_09975
ASOL:	BEN76_06765
ASJ:	AsACE_CH01477(benD)
MOI:	MOVS_09455
MHC:	MARHY0281(benD)
MAD:	HP15_1108
MPQ:	ABA45_01255(benD)
MARI:	ACP86_12000(benD)
AMG:	AMEC673_15500(benD)
CYQ:	Q91_2245
CZA:	CYCME_2563(benD)
HAK:	KO116_00235
HHU:	AR456_17680(benD)
APAC:	S7S_13320
MME:	Marme_1558
MARS:	A8C75_10510(benD)
OCE:	GU3_01775
GBI:	PG2T_09665
PSE:	NH8B_1753(benD)
RSC:	RCFBP_11859(benD)
RSL:	RPSI07_1884(benD)
RSN:	RSPO_c01859
RPI:	Rpic_1367
RPF:	Rpic12D_1431
RPJ:	N234_27840 N234_37270(benD)
RMN:	TK49_11665(benD)
RIN:	ACS15_1754
REU:	Reut_B4406
REH:	H16_A1960(benD)
CNC:	CNE_1c19300(benD)
RME:	Rmet_4885(benD)
CBW:	RR42_s0554
CCUP:	BKK81_23220(benD)
BMA:	BMAA0184(benD)
BMV:	BMASAVP1_1357(benD)
BML:	BMA10229_1552(benD)
BMN:	BMA10247_A0212(benD)
BMAL:	DM55_3534
BMAE:	DM78_4623
BMAQ:	DM76_4231
BMAI:	DM57_14455(benD)
BMAF:	DM51_3935
BMAZ:	BM44_3496
BMAB:	BM45_4332
BPS:	BPSS1906(benD)
BPM:	BURPS1710b_A1002(benD)
BPL:	BURPS1106A_A2584(benD)
BPD:	BURPS668_A2728(benD)
BPSE:	BDL_5312
BPSM:	BBQ_4224
BPSU:	BBN_5371
BPSD:	BBX_4477
BPZ:	BP1026B_II2045(benD)
BPQ:	BPC006_II2547
BPK:	BBK_4645
BPSH:	DR55_5828
BPSA:	BBU_4103
BPSO:	X996_5626
BUT:	X994_5189
BTE:	BTH_II0470
BTQ:	BTQ_3763
BTJ:	BTJ_4794
BTZ:	BTL_5580
BTD:	BTI_5084
BTV:	BTHA_4621
BTHE:	BTN_5251
BTHM:	BTRA_5521
BTHA:	DR62_5380(benD)
BTHL:	BG87_5596
BOK:	DM82_6196
BOC:	BG90_4468
BVI:	Bcep1808_5828
BVE:	AK36_5311
BUR:	Bcep18194_C7049
BCN:	Bcen_1303
BCH:	Bcen2424_6527
BCM:	Bcenmc03_6134
BCEN:	DM39_5094
BCEW:	DM40_5132
BCEO:	I35_7537
BAM:	Bamb_6581
BAC:	BamMC406_6296
BMU:	Bmul_3241
BMK:	DM80_4620
BMUL:	NP80_3313
BCED:	DM42_7057
BCEP:	APZ15_36345(benD)
BDL:	AK34_5715
BPYR:	ABD05_32070(benD)
BCON:	NL30_37450(benD)
BUB:	BW23_4425
BDF:	WI26_27680(benD)
BLAT:	WK25_16340(benD)
BTEI:	WS51_27265(benD)
BSEM:	WJ12_16745(benD)
BPSL:	WS57_00510(benD)
BMEC:	WJ16_18210(benD)
BSTG:	WT74_22610(benD)
BUG:	BC1001_1344
BGE:	BC1002_6177
BGO:	BM43_5498
BYI:	BYI23_D002180
BUK:	MYA_5341
BUO:	BRPE64_DCDS08510
BUE:	BRPE67_DCDS03930
BUL:	BW21_4619
BUQ:	AC233_11160
BUD:	AQ610_29995(benD)
BXE:	Bxe_B0912(benD)
BXB:	DR64_6233
BPH:	Bphy_5349
BPX:	BUPH_01851
BPY:	Bphyt_1594
BCAI:	K788_0005752
PSPW:	BJG93_32100(benD)
BPT:	Bpet1396(benD)
BHO:	D560_1121
BHM:	D558_1108
BTRM:	SAMEA390648701944(benD)
AXY:	AXYL_01800
AIS:	BUW96_17365
AFA:	UZ73_17880(benD)
PNA:	Pnap_2109
ACRA:	BSY15_1216
CSER:	CCO03_07070(benD)
ADN:	Alide_2649
HSE:	Hsero_1311(cbeD)
HSZ:	ACP92_06560(benD)
HRB:	Hrubri_1137(cbeD)
MASW:	AM586_16570(benD)
RBU:	PG1C_04535
DAR:	Daro_2781
TMZ:	Tmz1t_3099
SFH:	SFHH103_03581
SFD:	USDA257_c54420(benD)
EAD:	OV14_a1474(fabG2)
EAH:	FA04_27030(benD)
ARA:	Arad_12206
BOS:	BSY19_2041
XAU:	Xaut_4355
MET:	M446_1327
MNO:	Mnod_2371
RHZ:	RHPLAN_59320
PDE:	Pden_1180
PYE:	A6J80_01735
PCON:	B0A89_14340(benD)
CMAR:	IMCC12053_2583
CON:	TQ29_16490(benD)
RMM:	ROSMUCSMR3_03736(lvr)
NAR:	Saro_0540 Saro_3837
NPP:	PP1Y_AT15839 PP1Y_AT31260
NPN:	JI59_24685
NRE:	BES08_19580(benD)
SWI:	Swit_2636
SPHM:	G432_15085(benD)
SPHR:	BSY17_105
BLAS:	BSY18_3981
ERY:	CP97_14260
CNA:	AB433_18075
RGI:	RGI145_20865(benD)
AZL:	AZL_a07370(benD)
CGL:	NCgl2323(benD)
CGB:	cg2640(benD)
CGU:	WA5_2323(BenD)
CGT:	cgR_2288
CGS:	C624_11685(benD)
CGG:	C629_11695(benD)
CGM:	cgp_2640(benD)
CGJ:	AR0_11525(benD)
CGQ:	CGLAR1_11375(benD)
CGX:	SB89_11180(benD)
CEF:	CE2308
CHN:	A605_11140(benD)
CCN:	H924_10135(benD)
CMD:	B841_10265(benD)
CII:	CIMIT_11045(benD)
CMQ:	B840_09755(xylL)
CDX:	CDES_10945(benD)
CSTA:	CSTAT_12750(benD)
CCJZ:	ccrud_10715(benD)
BFV:	C628_11665(benD)
RHA:	RHA1_ro02387(benD)
ROP:	ROP_21010(benD)
ROA:	Pd630_LPD06583
RPY:	Y013_13600(benD)
RAV:	AAT18_24450(benD)
DTM:	BJL86_1202
APN:	Asphe3_35130
PSUL:	AU252_22710(benD)
KPL:	KPaMU14_10935(benD)
KFV:	AS188_00025(benD)
SATK:	SA2016_0099
SHT:	KO02_15975(benD)
HSI:	BOX17_05810(benD)

» show all

Reference

PMID:1740120

Authors

Neidle E, Hartnett C, Ornston LN, Bairoch A, Rekik M, Harayama S

Title

cis-diol dehydrogenases encoded by the TOL pWW0 plasmid xylL gene and the Acinetobacter calcoaceticus chromosomal benD gene are members of the short-chain alcohol dehydrogenase superfamily.

Journal

Eur J Biochem 204:113-20 (1992)
DOI:10.1111/j.1432-1033.1992.tb16612.x

Sequence

[aci:ACIAD1439]

All links

Ontology (5)   
   KEGG BRITE (3)   
   GO (1)   
   COG (1)   
Pathway (13)   
   KEGG PATHWAY (12)   
   KEGG MODULE (1)   
Chemical reaction (12)   
   KEGG ENZYME (1)   
   KEGG REACTION (8)   
   KEGG RCLASS (3)   
Gene (876)   
   KEGG GENES (356)   
   KEGG MGENES (413)   
   RefGene (106)   
   OC (1)   
Protein sequence (211)   
   UniProt (210)   
   SWISS-PROT (1)   
Literature (1)   
   PubMed (1)   
All databases (1118)   

Download RDF

ENZYME: 1.3.1.25

Entry

EC 1.3.1.25 Enzyme

Name

1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase;
3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase;
3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase;
dihydrodihydroxybenzoate dehydrogenase;
DHBDH;
cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase;
2-hydro-1,2-dihydroxybenzoate dehydrogenase;
cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase;
dihydrodihydroxybenzoate dehydrogenase;
(1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)

Class

Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)

Reaction(IUBMB)

(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+ [RN:R00813]

Reaction(KEGG)

R00813;
(other) R08111 R08112 R08113

Substrate

(1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate [CPD:C06321];
NAD+ [CPD:C00003]

Product

catechol [CPD:C00090];
CO2 [CPD:C00011];
NADH [CPD:C00004];
H+ [CPD:C00080]

History

EC 1.3.1.25 created 1976, modified 2004 (EC 1.3.1.55 created 1999, incorporated 2004)

Pathway

ec00362	Benzoate degradation
ec00364	Fluorobenzoate degradation
ec01100	Metabolic pathways
ec01120	Microbial metabolism in diverse environments

Orthology

K05783

dihydroxycyclohexadiene carboxylate dehydrogenase

Genes

EFE:	EFER_1485(benD)
KPN:	KPN_01869
KPU:	KP1_2934
KPM:	KPHS_28390
KPP:	A79E_2376
KPK:	A593_24210(benD)
KPH:	KPNIH24_14210(benD)
KPZ:	KPNIH27_13570(benD)
KPV:	KPNIH29_14240(benD)
KPW:	KPNIH30_14505(benD)
KPY:	KPNIH31_13520(benD)
KPG:	KPNIH32_14400(benD)
KPC:	KPNIH10_14040(benD)
KPQ:	KPR0928_14020(benD)
KPT:	VK055_0615
KPE:	KPK_2488(cbeD)
KPO:	KPN2242_12265(benD)
KPR:	KPR_2933(benD)
KPJ:	N559_2421
KPI:	D364_09585(benD)
KPA:	KPNJ1_02608
KPS:	KPNJ2_02563
KPX:	PMK1_04210(lvr)
KPB:	FH42_05420(benD)
KPNE:	KU54_012115(benD)
KPNU:	LI86_12050(benD)
KVA:	Kvar_2435
KVD:	KR75_22145(benD)
KVQ:	SP68_02890(benD)
KOC:	AB185_22235(benD)
KQU:	AVR78_18380(benD)
EAE:	EAE_19880(benD)
EAR:	CCG29904
CAF:	AL524_15085(benD)
EBT:	EBL_c18160
ROR:	RORB6_06755(benD)
RON:	TE10_13830(benD)
PGE:	LG71_16210(benD)
EBF:	D782_2133
SMAF:	D781_2850
SMW:	SMWW4_v1c30600
SRZ:	AXX16_2219
XSA:	SB85_10140(benD)
PSD:	DSC_14910(benD)
VNA:	PN96_18365(benD)
VEJ:	VEJY3_17926(benD)
PAE:	PA2515(xylL)
PAEV:	N297_2586
PAEI:	N296_2586
PAU:	PA14_32130(xylL)
PAP:	PSPA7_2722(xylL)
PAG:	PLES_27801(xylL)
PAF:	PAM18_2524(benD)
PNC:	NCGM2_3520(benD)
PAEB:	NCGM1900_4012(benD)
PDK:	PADK2_12670(benD)
PSG:	G655_12450(benD)
PRP:	M062_13075(benD)
PAEP:	PA1S_13070(benD)
PAER:	PA1R_gp0309
PAEM:	U769_12650(benD)
PAEL:	T223_14270(benD)
PAES:	SCV20265_2794
PAEU:	BN889_02739(benD)
PAEG:	AI22_20850(benD)
PAEC:	M802_2583
PAEO:	M801_2451
PMK:	MDS_4167
PRE:	PCA10_30910(benD)
PPSE:	BN5_3608(benD)
PCQ:	PcP3B5_23360(lvr)
PPU:	PP_3164(benD)
PPF:	Pput_2551
PPG:	PputGB1_2685
PPW:	PputW619_2707
PPT:	PPS_2762
PPB:	PPUBIRD1_2569(benD)
PPI:	YSA_10652
PPX:	T1E_1059(benD)
PPUH:	B479_13460(benD)
PPUT:	L483_17645(benD)
PPUN:	PP4_25400(benD) PP4_48180(benD)
PPUD:	DW66_3021
PFV:	Psefu_2026
PMON:	X969_13160(benD)
PMOT:	X970_12805(benD)
PPJ:	RK21_01914
PFL:	PFL_3855(xylL)
PPRC:	PFLCHA0_c39130(xylL)
PPRO:	PPC_3951(benD)
PFO:	Pfl01_2324 Pfl01_2965(benD)
PFE:	PSF113_2894(benD)
PFN:	HZ99_02920(benD)
PFX:	A7318_13915(benD)
PMAN:	OU5_6167(xylL)
PAZO:	AYR47_21845(benD)
PEN:	PSEEN3140(benD)
PSA:	PST_1670(benD)
PSR:	PSTAA_1698(benD)
PSC:	A458_09170(benD)
PSJ:	PSJM300_08880(benD)
PSH:	Psest_2696
PSTU:	UIB01_13630(benD)
PBM:	CL52_07430(benD)
PBA:	PSEBR_a2882
PPUU:	PputUW4_03254(xylL)
PDR:	H681_11365(benD)
PSV:	PVLB_12230(benD)
PKC:	PKB_2103(xylL)
PCH:	EY04_20395(benD)
PCZ:	PCL1606_21670
PCP:	JM49_10825(benD)
PFZ:	AV641_09800(benD)
PALK:	PSAKL28_52390
PSES:	PSCI_4806(benD)
PSEM:	TO66_21090(benD)
PPSY:	AOC04_06645(benD)
PSOS:	POS17_3976(benD)
PFK:	PFAS1_22860(benD)
AVN:	Avin_08620(benD)
AVL:	AvCA_08620(benD)
AVD:	AvCA6_08620(benD)
ACX:	Achr_32810(benD)
PCR:	Pcryo_1264
PSO:	PSYCG_06665(benD)
PALI:	A3K91_1588
PSPG:	AK823_04985
PSYG:	AK825_05000
ACB:	A1S_1212
ABY:	ABAYE2558(benD)
ABC:	ACICU_01189
ABN:	AB57_1347
ABB:	ABBFA_002367
ABX:	ABK1_1644
ABZ:	ABZJ_01348
ABR:	ABTJ_02517
ABD:	ABTW07_1376
ABH:	M3Q_1568
ABAD:	ABD1_12210(benD)
ABJ:	BJAB07104_01359
ABAB:	BJAB0715_01371
ABAJ:	BJAB0868_01307
ABAZ:	P795_11430
ABK:	LX00_05835
ABAU:	IX87_04590
ABAA:	IX88_08130
ABW:	BL01_13775
ABAL:	ABLAC_20300
ACC:	BDGL_000463(benD)
ANO:	RR32_12270
ACD:	AOLE_13350(benD)
ACI:	ACIAD1439(benD)
ATT:	AMQ28_00600
AEI:	AOY20_11285
AJO:	RZ95_08915
ACW:	A0J50_11650
ACV:	AMD27_07845
AJN:	BVL33_09975
ASOL:	BEN76_06765
ASJ:	AsACE_CH01477(benD)
MOI:	MOVS_09455
MHC:	MARHY0281(benD)
MAD:	HP15_1108
MPQ:	ABA45_01255(benD)
MARI:	ACP86_12000(benD)
AMG:	AMEC673_15500(benD)
CYQ:	Q91_2245
CZA:	CYCME_2563(benD)
HAK:	KO116_00235
HHU:	AR456_17680(benD)
APAC:	S7S_13320
MME:	Marme_1558
MARS:	A8C75_10510(benD)
OCE:	GU3_01775
GBI:	PG2T_09665
PSE:	NH8B_1753(benD)
RSC:	RCFBP_11859(benD)
RSL:	RPSI07_1884(benD)
RSN:	RSPO_c01859
RPI:	Rpic_1367
RPF:	Rpic12D_1431
RPJ:	N234_27840 N234_37270(benD)
RMN:	TK49_11665(benD)
RIN:	ACS15_1754
REU:	Reut_B4406
REH:	H16_A1960(benD)
CNC:	CNE_1c19300(benD)
RME:	Rmet_4885(benD)
CBW:	RR42_s0554
CCUP:	BKK81_23220(benD)
BMA:	BMAA0184(benD)
BMV:	BMASAVP1_1357(benD)
BML:	BMA10229_1552(benD)
BMN:	BMA10247_A0212(benD)
BMAL:	DM55_3534
BMAE:	DM78_4623
BMAQ:	DM76_4231
BMAI:	DM57_14455(benD)
BMAF:	DM51_3935
BMAZ:	BM44_3496
BMAB:	BM45_4332
BPS:	BPSS1906(benD)
BPM:	BURPS1710b_A1002(benD)
BPL:	BURPS1106A_A2584(benD)
BPD:	BURPS668_A2728(benD)
BPSE:	BDL_5312
BPSM:	BBQ_4224
BPSU:	BBN_5371
BPSD:	BBX_4477
BPZ:	BP1026B_II2045(benD)
BPQ:	BPC006_II2547
BPK:	BBK_4645
BPSH:	DR55_5828
BPSA:	BBU_4103
BPSO:	X996_5626
BUT:	X994_5189
BTE:	BTH_II0470
BTQ:	BTQ_3763
BTJ:	BTJ_4794
BTZ:	BTL_5580
BTD:	BTI_5084
BTV:	BTHA_4621
BTHE:	BTN_5251
BTHM:	BTRA_5521
BTHA:	DR62_5380(benD)
BTHL:	BG87_5596
BOK:	DM82_6196
BOC:	BG90_4468
BVI:	Bcep1808_5828
BVE:	AK36_5311
BUR:	Bcep18194_C7049
BCN:	Bcen_1303
BCH:	Bcen2424_6527
BCM:	Bcenmc03_6134
BCEN:	DM39_5094
BCEW:	DM40_5132
BCEO:	I35_7537
BAM:	Bamb_6581
BAC:	BamMC406_6296
BMU:	Bmul_3241
BMK:	DM80_4620
BMUL:	NP80_3313
BCED:	DM42_7057
BCEP:	APZ15_36345(benD)
BDL:	AK34_5715
BPYR:	ABD05_32070(benD)
BCON:	NL30_37450(benD)
BUB:	BW23_4425
BDF:	WI26_27680(benD)
BLAT:	WK25_16340(benD)
BTEI:	WS51_27265(benD)
BSEM:	WJ12_16745(benD)
BPSL:	WS57_00510(benD)
BMEC:	WJ16_18210(benD)
BSTG:	WT74_22610(benD)
BUG:	BC1001_1344
BGE:	BC1002_6177
BGO:	BM43_5498
BYI:	BYI23_D002180
BUK:	MYA_5341
BUO:	BRPE64_DCDS08510
BUE:	BRPE67_DCDS03930
BUL:	BW21_4619
BUQ:	AC233_11160
BUD:	AQ610_29995(benD)
BXE:	Bxe_B0912(benD)
BXB:	DR64_6233
BPH:	Bphy_5349
BPX:	BUPH_01851
BPY:	Bphyt_1594
BCAI:	K788_0005752
PSPW:	BJG93_32100(benD)
BPT:	Bpet1396(benD)
BHO:	D560_1121
BHM:	D558_1108
BTRM:	SAMEA390648701944(benD)
AXY:	AXYL_01800
AIS:	BUW96_17365
AFA:	UZ73_17880(benD)
PNA:	Pnap_2109
ACRA:	BSY15_1216
CSER:	CCO03_07070(benD)
ADN:	Alide_2649
HSE:	Hsero_1311(cbeD)
HSZ:	ACP92_06560(benD)
HRB:	Hrubri_1137(cbeD)
MASW:	AM586_16570(benD)
RBU:	PG1C_04535
DAR:	Daro_2781
TMZ:	Tmz1t_3099
SFH:	SFHH103_03581
SFD:	USDA257_c54420(benD)
EAD:	OV14_a1474(fabG2)
EAH:	FA04_27030(benD)
ARA:	Arad_12206
BOS:	BSY19_2041
XAU:	Xaut_4355
MET:	M446_1327
MNO:	Mnod_2371
RHZ:	RHPLAN_59320
PDE:	Pden_1180
PYE:	A6J80_01735
PCON:	B0A89_14340(benD)
CMAR:	IMCC12053_2583
CON:	TQ29_16490(benD)
RMM:	ROSMUCSMR3_03736(lvr)
NAR:	Saro_0540 Saro_3837
NPP:	PP1Y_AT15839 PP1Y_AT31260
NPN:	JI59_24685
NRE:	BES08_19580(benD)
SWI:	Swit_2636
SPHM:	G432_15085(benD)
SPHR:	BSY17_105
BLAS:	BSY18_3981
ERY:	CP97_14260
CNA:	AB433_18075
RGI:	RGI145_20865(benD)
AZL:	AZL_a07370(benD)
CGL:	NCgl2323(benD)
CGB:	cg2640(benD)
CGU:	WA5_2323(BenD)
CGT:	cgR_2288
CGS:	C624_11685(benD)
CGG:	C629_11695(benD)
CGM:	cgp_2640(benD)
CGJ:	AR0_11525(benD)
CGQ:	CGLAR1_11375(benD)
CGX:	SB89_11180(benD)
CEF:	CE2308
CHN:	A605_11140(benD)
CCN:	H924_10135(benD)
CMD:	B841_10265(benD)
CII:	CIMIT_11045(benD)
CMQ:	B840_09755(xylL)
CDX:	CDES_10945(benD)
CSTA:	CSTAT_12750(benD)
CCJZ:	ccrud_10715(benD)
BFV:	C628_11665(benD)
RHA:	RHA1_ro02387(benD)
ROP:	ROP_21010(benD)
ROA:	Pd630_LPD06583
RPY:	Y013_13600(benD)
RAV:	AAT18_24450(benD)
DTM:	BJL86_1202
APN:	Asphe3_35130
PSUL:	AU252_22710(benD)
KPL:	KPaMU14_10935(benD)
KFV:	AS188_00025(benD)
SATK:	SA2016_0099
SHT:	KO02_15975(benD)
HSI:	BOX17_05810(benD)

» show all

Reference

1 [PMID:4341530]

Authors

Reiner AM.

Title

Metabolism of aromatic compounds in bacteria. Purification and properties of the catechol-forming enzyme, 3,5-cyclohexadiene-1,2-diol-1-carboxylic acid (NAD + ) oxidoreductase (decarboxylating).

Journal

J. Biol. Chem. 247 (1972) 4960-5.

Reference

2 [PMID:1740120]

Authors

Neidle E, Hartnett C, Ornston LN, Bairoch A, Rekik M, Harayama S.

Title

cis-diol dehydrogenases encoded by the TOL pWW0 plasmid xylL gene and the Acinetobacter calcoaceticus chromosomal benD gene are members of the short-chain alcohol dehydrogenase superfamily.

Journal

Eur. J. Biochem. 204 (1992) 113-20.

Sequence

[aci:ACIAD1439]

Other DBs

ExplorEnz - The Enzyme Database:

1.3.1.25

IUBMB Enzyme Nomenclature:

1.3.1.25

ExPASy - ENZYME nomenclature database:

1.3.1.25

UM-BBD (Biocatalysis/Biodegradation Database):

1.3.1.25

BRENDA, the Enzyme Database:

1.3.1.25

CAS:

60496-16-4

All links

Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG REACTION (4)   
   KEGG RCLASS (2)   
Gene (876)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (356)   
   KEGG MGENES (413)   
   RefGene (106)   
Protein sequence (1229)   
   UniProt (458)   
   SWISS-PROT (2)   
   RefSeq(pep) (769)   
DNA sequence (3867)   
   RefSeq(nuc) (3291)   
   GenBank (292)   
   EMBL (284)   
Enzyme (1)   
   UMBBD-EC (1)   
All databases (6000)   

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REACTION: R08113

Entry

R08113 Reaction

Name

4-fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate:NAD+oxidoreductase (decarboxylating)

Definition

4-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ <=> 4-Fluorocatechol + NADH + CO2 + H+

Equation

C16480 + C00003 <=> C16473 + C00004 + C00011 + C00080

Reaction class

RC00001	C00003_C00004
RC00271	C16473_C16480

Enzyme

1.3.1.25

Pathway

rn00364	Fluorobenzoate degradation
rn01100	Metabolic pathways
rn01120	Microbial metabolism in diverse environments
rn01220	Degradation of aromatic compounds

Orthology

K05783

dihydroxycyclohexadiene carboxylate dehydrogenase [EC:1.3.1.25 1.3.1.-]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
   UMBBD-RN (1)   
Gene (357)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (356)   
All databases (376)   

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