KEGG ORTHOLOGY: K08318

ORTHOLOGY: K08318

Entry

K08318                      KO

Symbol

yihU

Name

4-hydroxybutyrate dehydrogenase / sulfolactaldehyde 3-reductase [EC:1.1.1.61 1.1.1.373]

Pathway

map00650

Butanoate metabolism

map01100

Metabolic pathways

map01200

Carbon metabolism

Reaction

R01644

4-hydroxybutanoate:NAD+ oxidoreductase

R10719

(2S)-2,3-dihydroxypropane-1-sulfonate:NAD+ 3-oxidoreductase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    K08318  yihU; 4-hydroxybutyrate dehydrogenase / sulfolactaldehyde 3-reductase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.61  4-hydroxybutyrate dehydrogenase
     K08318  yihU; 4-hydroxybutyrate dehydrogenase / sulfolactaldehyde 3-reductase
    1.1.1.373  sulfolactaldehyde 3-reductase
     K08318  yihU; 4-hydroxybutyrate dehydrogenase / sulfolactaldehyde 3-reductase

Other DBs

COG:

COG2084

GO:	0047577 0061596

Genes

ECO:	b3882(yihU)

ECJ:	JW3853(yihU)

ECD:	ECDH10B_4072(yihU)

EBW:	BWG_3552(yihU)

ECOK:

ECMDS42_3321(yihU)

ECOC:

C3026_20985

ECE:	Z5420(yihU)

ECS:	ECs_4805(yihU)

ECF:	ECH74115_5329

ETW:	ECSP_4938(yihU)

ELX:	CDCO157_4544

EOI:	ECO111_4702(yihU)

EOJ:	ECO26_4708(yihU)

EOH:	ECO103_4289(yihU)

ESL:

O3K_24495

ESO:

O3O_00840

ESM:

O3M_24415

ECK:	EC55989_4353

ECG:	E2348C_4180

EOK:	G2583_4683(yihU)

ELR:	ECO55CA74_22435

ELH:

ETEC_4152

ECW:	EcE24377A_4405

EUN:	UMNK88_4715

ECP:

ECP_4088

ENA:	ECNA114_3975(yihU)

ECOS:

EC958_4354(yihU)

ECV:	APECO1_2588

ECOA:

APECO78_00150

ECX:	EcHS_A4104

ECM:	EcSMS35_4267

ECY:

ECSE_4165

ECR:	ECIAI1_4082(yihU)

ECQ:	ECED1_4582(yihU)

EUM:	ECUMN_4409(yihU)

ECT:	ECIAI39_3118(yihU)

EOC:	CE10_4546(yihU)

EBR:	ECB_03767(yihU)

ECOB:

C3029_01010

EBL:	ECD_03767(yihU)

EBE:	B21_03716(yihU)

EBD:

ECBD_4145

ECI:	UTI89_C4463(yihU)

EIH:	ECOK1_4346

ECZ:	ECS88_4324

ECC:	c4826(yihU)

ELO:	EC042_4256

ELN:	NRG857_19350

ESE:

ECSF_3733

ECL:	EcolC_4139

EKO:	EKO11_4480

EKF:	KO11_03195(yihU)

EAB:	ECABU_c43810

EDH:	EcDH1_4104

EDJ:	ECDH1ME8569_3753(yihU)

ELU:	UM146_19610

ELW:	ECW_m4186(yihU)

ELL:	WFL_20395(yihU)

ELC:	i14_4419(yihU)

ELD:	i02_4419(yihU)

ELP:	P12B_c3997

ELF:

LF82_610

ECOL:

LY180_20115

ECOI:

ECOPMV1_04237(garR_4)

ECOJ:

P423_21510

EMA:	C1192_16095

ESZ:	FEM44_09220(yihU)

ERUY:

OSH18_12240(yihU)

STY:	STY3855(yihU)

STT:	t3598(yihU)

SEX:	STBHUCCB_37870

SENT:

TY21A_18195

STM:	STM4023(yihU)

SEO:	STM14_4836(yihU)

SEV:	STMMW_39871

SEY:	SL1344_3969(yihU)

SEM:	STMDT12_C41660

SEJ:	STMUK_4006(yihU)

SEB:	STM474_4200(yihU)

SEF:	UMN798_4360(yihU)

SETU:

STU288_20245

SETC:

CFSAN001921_20325

SENR:

STMDT2_38831(yihU)

SEND:

DT104_40301(yihU)

SENI:

CY43_21025

SEEN:

SE451236_00795

SPT:	SPA3864(yihU)

SEK:

SSPA3594

SPQ:	SPAB_04982

SEI:	SPC_4126(yihU)

SEC:	SCH_3913(yihU)

SEH:	SeHA_C4346

SHB:

SU5_0119

SENH:

CFSAN002069_11975

SEEH:

SEEH1578_06140

SEE:	SNSL254_A4300

SENN:

SN31241_47150

SEW:	SeSA_A4233

SEA:	SeAg_B4255

SENS:

Q786_19720

SED:

SeD_A4411

SEG:	SG3402(yihU)

SEL:	SPUL_3649(yihU)

SEGA:

SPUCDC_3635(yihU)

SET:	SEN3811(yihU)

SENA:

SENO:

SENV:

SENQ:

SENL:

SENJ:

SEEC:

SEEB:

SEEP:

SENB:

SENE:

SENC:

SES:	SARI_03643

SBG:	SBG_3540(yihU)

SBZ:

A464_4064

SBV:	N643_17755

SALZ:

EOS98_22210

SFL:	SF3954(yihU)

SFX:	S3792(yihU)

SFV:	SFV_3617(yihU)

SFE:	SFxv_4308(yihU)

SFN:

SFy_5649

SFS:

SFyv_5712

SFT:	NCTC1_04280(yihU)

SSN:	SSON_4048(yihU)

SBO:	SBO_3887(yihU)

SHQ:	A0259_00965

ENC:

ECLG:

ECLE:

ECLN:

ECLI:

ECLX:

ECLY:

ECLZ:

ECLO:

EHM:	AB284_04510

EXF:	BFV63_21885

ECLA:

ECNIH3_21835

ECLC:

ECR091_21765

EAU:	DI57_18815

EKB:	BFV64_23245

ENO:	ECENHK_21935

EEC:	EcWSU1_04480(yihU)

ELG:	BH714_14860

ECAN:

CWI88_22490

ERN:	BFV67_21865

ECLS:

LI67_024265

ECHG:

FY206_24275(yihU)

EPT:	HWQ17_13645(yihU)

EAS:	Entas_4393

LNI:	CWR52_12850

EBG:	FAI37_07030(yihU)

END:	A4308_06885

ENZ:	G0034_22840(yihU)

ENS:	HWQ15_07830(yihU)

ENK:	LOC22_10415(yihU)

EHU:	D5067_0023105(yihU)

EMOR:

L6Y89_22015(yihU)

ESA:

ESA_04058

CSK:

ES15_0037

CSZ:	CSSP291_18805

CSJ:	CSK29544_00987

CCON:

AFK62_19810

CSI:	P262_05706

CMJ:	AFK66_000210

CUI:	AFK65_19600

CMW:	AFK63_18745

CTU:	CTU_41740(yihU)

KLW:	DA718_29160

KAR:	LGL98_24785(yihU)

KGR:	JJJ10_27435(yihU)

KLC:	K7H21_27640(yihU)

CRO:

ROD_38791

CKO:

CKO_03131

CFD:	CFNIH1_06955

CBRA:

A6J81_16395

CWE:	CO701_21335

CYO:	CD187_23365

CPOT:

FOB25_10635(yihU)

CFQ:	C2U38_25190

CSED:

JY391_21700(yihU)

CAMA:

F384_21000

CAF:	AL524_03835

CIF:	AL515_02035

CFAR:

CI104_24475

CIR:	C2U53_10580

CIE:	AN232_03630

CPAR:

CUC49_19980

CTEL:

GBC03_05230(yihU)

CITZ:

E4Z61_16335(yihU)

CARS:

E1B03_01740(yihU)

CIX:	M4I31_23205(yihU)

CIB:	HF677_022975(yihU)

CENS:

P2W74_22615(yihU)

ESC:	Entcl_1241

LAX:	APT61_00220

LEI:	C2U54_04485

LEE:	DVA44_23385

LER:	GNG29_22755(yihU)

LEA:	GNG26_22095(yihU)

LPNU:

KQ929_20900(yihU)

LEY:	DVA43_18260

LAZ:	A8A57_21395

BAGE:

BADSM9389_41410

AHN:	NCTC12129_04955(garR_2)

ASUB:

NLZ15_21985(yihU)

KIN:	AB182_24960

SUPE:

P0H77_22760(yihU)

TOE:	QMG90_04995(yihU)

EBB:	F652_3768(yihU)

YAL:

AT01_41

SFW:	WN53_01445

SFG:	AV650_24195

SFO:	Z042_05670

RAH:	Rahaq_4078

RACE:

JHW33_14720(yihU)

RAQ:	Rahaq2_4181

RAA:

Q7S_20720

RVC:	J9880_05845(yihU)

RBON:

QNM34_09555(yihU)

CARU:

P0E69_10920(yihU)

NIG:	C1N62_08750

PAM:	PANA_3497(yihU)

PLF:	PANA5342_0554(yihU)

PAJ:	PAJ_2726(yihU)

PAQ:	PAGR_g0536

PSTW:

DSJ_21395

MTHI:

C7M52_01008(yihU)

HPAR:

AL518_02780

PRAG:

EKN56_14665

LRI:	NCTC12151_00811(Hgd)

BSUN:

A4G13_00755

VSI:	MTO69_14805(yihU)

VSH:	BSZ05_23595

VSR:	Vspart_03220(hgd)

VGI:	MID13_22250(yihU)

VCRA:

IS519_24295(yihU)

AEI:	AOY20_11465

SROS:

BBH56_04580

THIN:

CRN91_08445

CUH:	BJN34_35670

BFN:

OI25_3878

PDIO:

PDMSB3_2375.1(yihU)

BBH:	BN112_4333

BBR:

BB4070

BBM:	BN115_3759

BBX:	BBS798_3863

BGM:	CAL15_12665

BGV:	CAL12_07435

AXY:	AXYL_01396

AIS:	BUW96_19440

ADY:	HLG70_04255

APES:

FOC84_05705

AAEG:

RA224_25925 RA224_26385

POLL:

ACIP:

ACIS:

ARAD:

CODO:

CTEZ:

CT3_33130(yihU)

AANT:

HUK68_04545

ADN:	Alide_0276

ADK:	Alide2_0223

DIH:	G7047_09480

DAER:

H9K75_01440

ATA:	AWN88_00520

RHT:	NT26_p10281

BVES:

QO058_20595

CHEL:

AL346_05120

RBM:

TEF_16385

PSF:	PSE_2341(garR)

PHR:	C6569_18140

PSTG:

E8M01_11950

PAQT:

E8L99_05025

RID:	RIdsm_01292(hgd_4)

PYE:	A6J80_20645

NOV:	TQ38_027345

NOT:	C7W88_20575

SPKC:

SBIN:

SPHB:

SHUM:

SVC:	STVA_25540(garR)

STEL:

STAQ_18190

ABS:	AZOBR_p340215

AARE:

D3093_32875

HTQ:	FRZ44_48020(yihU)

HADH:

NACI:

THAR:

Reference

PMID:19372223

Authors

Saito N, Robert M, Kochi H, Matsuo G, Kakazu Y, Soga T, Tomita M

Title

Metabolite profiling reveals YihU as a novel hydroxybutyrate dehydrogenase for alternative succinic semialdehyde metabolism in Escherichia coli.

Journal

J Biol Chem 284:16442-51 (2009)
DOI:10.1074/jbc.M109.002089

Reference

PMID:24463506

Authors

Denger K, Weiss M, Felux AK, Schneider A, Mayer C, Spiteller D, Huhn T, Cook AM, Schleheck D

Title

Sulphoglycolysis in Escherichia coli K-12 closes a gap in the biogeochemical sulphur cycle.

Journal

Nature 507:114-7 (2014)
DOI:10.1038/nature12947

Sequence

[eco:b3882]

All links

Ontology (5)   
   KEGG BRITE (2)   
   GO (2)   
   COG (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (6)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
   KEGG RCLASS (2)   
Gene (2303)   
   KEGG GENES (297)   
   KEGG MGENES (1646)   
   RefGene (351)   
   OC (9)   
Literature (2)   
   PubMed (2)   
All databases (2322)   

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