KEGG   ORTHOLOGY: K10158Help
Entry
K10158                      KO                                     

Name
B3GAT3
Definition
galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 [EC:2.4.1.135]
Pathway
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
Glycosaminoglycan biosynthesis - heparan sulfate / heparin
Module
M00057  
Glycosaminoglycan biosynthesis, linkage tetrasaccharide
Disease
H01498  
Multiple joint dislocations, short stature, craniofacial dysmorphism, and congenital heart defects (JDSSDHD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Glycan biosynthesis and metabolism
   00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
    K10158  B3GAT3; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
   00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
    K10158  B3GAT3; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Glycosaminoglycan metabolism
    M00057  Glycosaminoglycan biosynthesis, linkage tetrasaccharide
     K10158  B3GAT3; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.135  galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
     K10158  B3GAT3; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
Glycosyltransferases [BR:ko01003]
 Glycan extension
  O-Glycan
   K10158  B3GAT3; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
BRITE hierarchy
Other DBs
RN: 
GO: 
CAZy: 
Genes
HSA: 
26229(B3GAT3)
PTR: 
PPS: 
103783318(B3GAT3)
GGO: 
109028750(B3GAT3)
PON: 
100458701(B3GAT3)
NLE: 
100592146(B3GAT3)
MCC: 
718744(B3GAT3)
MCF: 
101867087(B3GAT3)
CSAB: 
103234006(B3GAT3)
RRO: 
104679349(B3GAT3)
CJC: 
100395367(B3GAT3)
SBQ: 
101034661(B3GAT3)
MMU: 
72727(B3gat3)
RNO: 
293722(B3gat3)
CGE: 
100689419(B3gat3)
NGI: 
103737681(B3gat3)
HGL: 
101717898(B3gat3)
CCAN: 
109681240(B3gat3)
OCU: 
100350294(B3GAT3)
TUP: 
102472891(B3GAT3)
CFA: 
483785(B3GAT3)
AML: 
100467358(B3GAT3)
UMR: 
103678187(B3GAT3)
FCA: 
101089044(B3GAT3)
PTG: 
102948861(B3GAT3)
AJU: 
106981737(B3GAT3)
BTA: 
404162(B3GAT3)
BOM: 
102269297(B3GAT3)
BIU: 
109554349(B3GAT3)
PHD: 
102342113(B3GAT3)
CHX: 
102172516(B3GAT3)
OAS: 
101111917(B3GAT3)
SSC: 
397642(B3GAT3)
CFR: 
102505525(B3GAT3)
BACU: 
103002629(B3GAT3)
LVE: 
103078862(B3GAT3)
ECB: 
100063587(B3GAT3)
MYB: 
102260939(B3GAT3)
MYD: 
102752313(B3GAT3)
HAI: 
109384098(B3GAT3)
RSS: 
109435830(B3GAT3)
PALE: 
102891455(B3GAT3)
LAV: 
100672369(B3GAT3)
MDO: 
100010236(B3GAT3)
SHR: 
100935255(B3GAT3)
OAA: 
100075413(B3GAT3)
PHI: 
102105592(B3GAT3)
CLV: 
ASN: 
102375316(B3GAT3)
AMJ: 
102563043(B3GAT3)
PSS: 
102460502(B3GAT3)
CMY: 
102941550(B3GAT3)
CPIC: 
101940176(B3GAT3)
ACS: 
100567109(b3gat3)
PBI: 
103057546(B3GAT3)
GJA: 
107120072(B3GAT3)
XLA: 
398597(b3gat3.L)
XTR: 
594895(b3gat3)
DRE: 
192334(b3gat3)
IPU: 
108268305(b3gat3)
TRU: 
654312(b3gat3)
TNG: 
LCO: 
104918106(b3gat3)
MZE: 
101480695(b3gat3)
OLA: 
100049460(b3gat3)
XMA: 
102238000(b3gat3)
CSEM: 
103384246(b3gat3)
SASA: 
106578098(b3gat3)
LCM: 
102364764(B3GAT3)
CMK: 
103171591(b3gat3)
BFO: 
CIN: 
778533(uglcat1)
SPU: 
SKO: 
DME: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD16673(Dsim_GD16673)
DWI: 
DYA: 
Dyak_GE16334(Dyak_GlcAT-I)
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
413271(GlcAT-I)
BIM: 
BTER: 
SOC: 
AEC: 
PBAR: 
HST: 
CFO: 
NVI: 
100123025(B3gat)
TCA: 
BMOR: 
PXY: 
API: 
PHU: 
DPX: 
ISC: 
CEL: 
CBR: 
CBG01067(Cbr-sqv-8)
BMY: 
LOA: 
LGI: 
CRG: 
OBI: 
SMM: 
OVI: 
NVE: 
ADF: 
HMG: 
TAD: 
AQU: 
MBR: 
SRE: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Ouzzine M, Gulberti S, Netter P, Magdalou J, Fournel-Gigleux S
  Title
Structure/function of the human Ga1beta1,3-glucuronosyltransferase. Dimerization  and functional activity are mediated by two crucial cysteine residues.
  Journal
J Biol Chem 275:28254-60 (2000)
DOI:10.1074/jbc.M002182200
  Sequence
[hsa:26229]
Reference
  Authors
Kim BT, Tsuchida K, Lincecum J, Kitagawa H, Bernfield M, Sugahara K
  Title
Identification and characterization of three Drosophila melanogaster glucuronyltransferases responsible for the synthesis of the conserved glycosaminoglycan-protein linkage region of proteoglycans. Two novel homologs exhibit broad specificity toward oligosaccharides from proteoglycans, glycoproteins, and glycosphingolipids.
  Journal
J Biol Chem 278:9116-24 (2003)
DOI:10.1074/jbc.M209344200
  Sequence

DBGET integrated database retrieval system