KEGG   ORTHOLOGY: K10258Help
Entry
K10258                      KO                                     

Name
TER, TSC13, CER10
Definition
very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
Pathway
Fatty acid elongation
Biosynthesis of unsaturated fatty acids
Fatty acid metabolism
Module
M00415  
Fatty acid biosynthesis, elongation, endoplasmic reticulum
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Overview
   01212 Fatty acid metabolism
    K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
  Lipid metabolism
   00062 Fatty acid elongation
    K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
   01040 Biosynthesis of unsaturated fatty acids
    K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Fatty acid metabolism
    M00415  Fatty acid biosynthesis, elongation, endoplasmic reticulum
     K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.93  very-long-chain enoyl-CoA reductase
     K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
Lipid biosynthesis proteins [BR:ko01004]
 Fatty acid synthase
  Component type
   K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase
BRITE hierarchy
Other DBs
Genes
HSA: 
9524(TECR)
PTR: 
455786(TECR)
PPS: 
100971383(TECR)
GGO: 
PON: 
NLE: 
100581652(TECR)
MCC: 
718928(TECR)
MCF: 
101926702(TECR)
CSAB: 
103234044(TECR)
RRO: 
104661039(TECR)
CJC: 
100402213(TECR)
SBQ: 
101033875(TECR)
MMU: 
106529(Tecr)
RNO: 
191576(Tecr)
CGE: 
100761652(Tecr)
NGI: 
103751841(Tecr)
HGL: 
101716060(Tecr)
CCAN: 
109686636(Tecr)
OCU: 
103346023(TECR)
TUP: 
102480210(TECR)
CFA: 
476687(TECR)
AML: 
100467030(TECR)
UMR: 
103682180(TECR)
FCA: 
101091601(TECR)
PTG: 
102948536 102959844(TECR)
AJU: 
106986213(TECR)
BTA: 
614105(TECR)
BOM: 
102285957(TECR)
BIU: 
109561491(TECR)
PHD: 
102340071(TECR)
CHX: 
102187120(TECR)
OAS: 
101117331(TECR)
SSC: 
100515709(TECR)
CFR: 
102519742(TECR)
BACU: 
102997227(TECR)
LVE: 
103070891(TECR)
ECB: 
100065024(TECR)
MYB: 
102260613(TECR)
MYD: 
102751823(TECR)
HAI: 
109394266(TECR)
RSS: 
109442713 109454938(TECR)
PALE: 
102887858(TECR)
LAV: 
100674918(TECR)
MDO: 
100026440(TECR) 100032861
SHR: 
100914010(TECR)
OAA: 
100080249 100081999(TECR)
GGA: 
424491(TECR)
MGP: 
100545685(TECR)
CJO: 
107307749(TECR) 107317393
APLA: 
101799511(TECR)
TGU: 
100230168(TECR)
GFR: 
102032504(TECR)
FAB: 
101810425(TECR) 101812411
PHI: 
102099600(TECR) 106628096
CCW: 
104695353(TECR)
FPG: 
101910412 101911436
FCH: 
102049843 106631266
AAM: 
106484788 106499774(TECR)
ASN: 
102370679(TECR) 102383204
AMJ: 
102559187(TECR) 102575131
PSS: 
102457301(TECR) 102459125
CMY: 
102929357(TECR) 102931932
CPIC: 
101937001(TECR) 101945886
ACS: 
100560578 100566730(tecr)
PBI: 
103058993 103065171(TECR)
GJA: 
107112228 107117643(TECR)
XLA: 
108713542 380153(gpsn2) 444160(tecr.L)
XTR: 
493561(tecr) 780081
DRE: 
326954(tecrb) 566085(tecra) 798606(tecrl2a)
IPU: 
100528865(tecr) 108255190 108256782 108280320
TRU: 
101061272 101070143(tecr) 101076261
TNG: 
GSTEN00016634G001 GSTEN00019764G001 GSTEN00026306G001
LCO: 
104918595 104923104 104925392(tecr) 109139143
MZE: 
101469805 101471785 101483996(tecr) 106675772
OLA: 
101155407(tecr) 101163495 101171706
XMA: 
102220976 102224233 102224945(tecr)
CSEM: 
103377076 103383916(tecr) 103392722
SASA: 
106564267(tecr) 106569794 106590656 106591668 106595986
LCM: 
102353704(TECR) 102356009 102357997
CMK: 
103174648 103191170(tecr)
BFO: 
BRAFLDRAFT_123019
CIN: 
100183960
SPU: 
576023
SKO: 
100372208 102804355
DME: 
Dmel_CG10849(Sc2)
DPO: 
Dpse_GA10597
DAN: 
Dana_GF24232
DER: 
Dere_GG15168
DPE: 
Dper_GL16056
DSE: 
Dsec_GM14597
DSI: 
Dsimw501_GD13786(Dsim_GD13786)
DWI: 
Dwil_GK15900 Dwil_GK16849
DYA: 
Dyak_GE21388
DGR: 
Dgri_GH15767
DMO: 
Dmoj_GI12546
DVI: 
Dvir_GJ16064
MDE: 
101887858
AGA: 
AgaP_AGAP010714
AAG: 
AaeL_AAEL008740
CQU: 
CpipJ_CPIJ005584
AME: 
725146
BIM: 
100747299
BTER: 
100644169
SOC: 
105193039
AEC: 
105153980
PBAR: 
105433004
HST: 
105181228
CFO: 
105259215
NVI: 
100113603 107980451
TCA: 
659815
BMOR: 
101742899
PXY: 
105385206
API: 
100160468
PHU: 
Phum_PHUM037790
DPX: 
DAPPUDRAFT_199063
ISC: 
IscW_ISCW002618
CEL: 
CELE_C15F1.6(art-1)
CBR: 
CBG11196(Cbr-art-1)
NAI: 
NECAME_05127
BMY: 
Bm1_42555
LOA: 
LOAG_03140
TSP: 
Tsp_07269
HRO: 
HELRODRAFT_155722
LGI: 
LOTGIDRAFT_232335
CRG: 
105326706
OBI: 
106878132
SMM: 
Smp_081820.3
OVI: 
T265_14517
NVE: 
NEMVE_v1g147144
ADF: 
107334908 107357184
TAD: 
TRIADDRAFT_29423
AQU: 
100640363
ATH: 
AT3G55360(CER10)
ALY: 
ARALYDRAFT_906954(ATTSC13)
CRB: 
CARUB_v10017686mg
EUS: 
EUTSA_v10010564mg EUTSA_v10014355mg
BRP: 
103841442 103846366
BNA: 
106354472 106372195 106396280(ECR) 106415464 106424766
THJ: 
104801897 104806959 104810019
CIT: 
102617880 102619239
CIC: 
CICLE_v100162851m CICLE_v10032183mg
TCC: 
18586099
GRA: 
105776424 105780559
GHI: 
107904734 107934412 107959873
EGR: 
104454293
GMX: 
100780327 100785393 100798454
PVU: 
PHAVU_004G094100g PHAVU_008G208700g
VRA: 
106762967 106763737 106767496
VAR: 
108337072 108344754 108345163
CCAJ: 
109795557 109817368
MTR: 
MTR_5g087590 MTR_6g037340 MTR_6g043740
CAM: 
101496420 101508101(sr5a)
ADU: 
107466595 107496735
AIP: 
107609317 107619734
LJA: 
Lj0g3v0067399.1(Lj0g3v0067399.1) Lj0g3v0067409.1(Lj0g3v0067409.1)
LANG: 
109336026 109356796 109361041 109361308
FVE: 
101304235 101304356 101313554
PPER: 
18784679
PMUM: 
103332647
MDM: 
103406406 103408877 103409522 103424086 103438771 103445586
PXB: 
103935366 103946101
ZJU: 
107413483
CSV: 
101209094 101213758
CMO: 
103498153
RCU: 
8267764 8285429
JCU: 
105647736
POP: 
POPTR_0008s01370g(POPTRDRAFT_765095) POPTR_0008s05550g(POPTRDRAFT_720621) POPTR_0010s21190g(POPTRDRAFT_822481) POPTR_0010s25150g(POPTRDRAFT_770744) POPTR_0010s25160g
VVI: 
100266766
SLY: 
101255353 101263911
SPEN: 
107003199 107020319
SOT: 
102581846 102599277 102600822
INI: 
109148160 109186449 109187162
SIND: 
105166561 105171911
BVG: 
104904012 104907190
NNU: 
104594555
OSA: 
4324516
DOSA: 
Os01t0150000-01(Os01g0150000)
OBR: 
102717286 102717451
BDI: 
100830422 100835261
ATS: 
F775_31011
ZMA: 
100191179(AY106269) 103633692
SITA: 
101781761 105914355
PDA: 
103696797 103703465
EGU: 
105036394 105052214
MUS: 
103969301 103987000
ATR: 
18421589 18436069
SMO: 
SELMODRAFT_186154 SELMODRAFT_270920
PPP: 
PHYPADRAFT_203665 PHYPADRAFT_57093 PHYPADRAFT_67731
CRE: 
CHLREDRAFT_602
VCN: 
VOLCADRAFT_72272
OLU: 
OSTLU_49170
OTA: 
Ot03g04010
BPG: 
Bathy07g01910
MIS: 
MICPUN_60190
MPP: 
MICPUCDRAFT_49391
CSL: 
COCSUDRAFT_36177
CVR: 
CHLNCDRAFT_20573
APRO: 
F751_1654
CME: 
CYME_CMD146C
CCP: 
CHC_T00008438001
SCE: 
YDL015C(TSC13)
AGO: 
AGOS_AER215W
ERC: 
Ecym_5259
KLA: 
KLLA0C04367g
LTH: 
KLTH0E15950g
VPO: 
Kpol_1010p67
ZRO: 
ZYRO0A05038g
CGR: 
CAGL0K01837g
NCS: 
NCAS_0I01880(NCAS0I01880)
NDI: 
NDAI_0A06480(NDAI0A06480)
TPF: 
TPHA_0A04340(TPHA0A04340)
TBL: 
TBLA_0B01660(TBLA0B01660)
TDL: 
TDEL_0D04380(TDEL0D04380)
KAF: 
KAFR_0F02320(KAFR0F02320)
PPA: 
PAS_chr4_0780
DHA: 
DEHA2B00968g
PIC: 
PICST_39084(TSC13)
PGU: 
PGUG_00050
SPAA: 
SPAPADRAFT_132798
LEL: 
LELG_01381 LELG_05600
CAL: 
CAALFM_C101050CA(CaO19.3293)
CTP: 
CTRG_04406
COT: 
CORT_0B08560 CORT_0B11210
CDU: 
CD36_00990
CTEN: 
CANTEDRAFT_108493
YLI: 
YALI0A04983g
CLU: 
CLUG_00022
CAUR: 
QG37_05093
NCR: 
NCU03362
NTE: 
NEUTE1DRAFT117529(NEUTE1DRAFT_117529)
SMP: 
SMAC_04071
PAN: 
PODANSg6420
TTT: 
THITE_2123364
MTM: 
MYCTH_2145474
CTHR: 
CTHT_0001860
MGR: 
MGG_03250
TMN: 
UCRPA7_5124
FGR: 
FGSG_00629
FPU: 
FPSE_06407
FVR: 
FVEG_00568
FOX: 
FOXG_00946
NHE: 
NECHADRAFT_98899
TRE: 
TRIREDRAFT_105035
MAW: 
MAC_05645
MAJ: 
MAA_01851
CMT: 
CCM_05177
VAL: 
VDBG_05577
VDA: 
VDAG_07519
CFJ: 
CFIO01_07269
ELA: 
UCREL1_8704
SSL: 
SS1G_10706
BFU: 
BC1G_04255
MBE: 
MBM_02606
PSCO: 
LY89DRAFT_737543
GLZ: 
GLAREA_03598
ANI: 
AN1968.2
AFM: 
AFUA_4G10760
AOR: 
AOR_1_156074(AO090038000096) AOR_1_2872154(AO090003001139)
ANG: 
ANI_1_968184(An04g05930)
AFV: 
AFLA_026780 AFLA_125740
ACT: 
ACLA_049930
NFI: 
NFIA_105330
PCS: 
Pc22g07000
PDP: 
PDIP_33130
CIM: 
CIMG_01478
CPW: 
CPC735_049630
PBL: 
PAAG_02630
PBN: 
PADG_01649
URE: 
UREG_05117
ABE: 
ARB_02271
TVE: 
TRV_04982
AJE: 
HCAG_01670
PNO: 
SNOG_07392
PTE: 
PTT_16464
BZE: 
COCCADRAFT_34894
BSC: 
COCSADRAFT_104969
BOR: 
COCMIDRAFT_101215
ZTR: 
MYCGRDRAFT_98769
PFJ: 
MYCFIDRAFT_76038
BCOM: 
BAUCODRAFT_34915
NPA: 
UCRNP2_7555
TML: 
GSTUM_00001911001
SPO: 
SPBC646.07c
CNE: 
CNE01780
CNB: 
CNBE1760
CGI: 
CGB_E2340W
TMS: 
TREMEDRAFT_71207
TVS: 
TRAVEDRAFT_126270
DSQ: 
DICSQDRAFT_166875
PCO: 
PHACADRAFT_89473
SHS: 
STEHIDRAFT_141777
HIR: 
HETIRDRAFT_54691
PSQ: 
PUNSTDRAFT_116689
ADL: 
AURDEDRAFT_105341 AURDEDRAFT_152816
FME: 
FOMMEDRAFT_102627
GTR: 
GLOTRDRAFT_78098
LBC: 
LACBIDRAFT_251245
MRR: 
Moror_17838
CCI: 
CC1G_10032
SCM: 
SCHCODRAFT_67919
CPUT: 
CONPUDRAFT_99121
SLA: 
SERLADRAFT_449601
WSE: 
WALSEDRAFT_66778
WIC: 
J056_002528
UMA: 
UMAG_03622
PFP: 
PFL1_02440
MGL: 
MGL_0166
PGR: 
PGTG_02971
MLR: 
MELLADRAFT_87292
DDI: 
DDB_G0270270(gpsn2)
DPP: 
DICPUDRAFT_52983
DFA: 
DFA_02956(gpsn2)
EHI: 
EHI_045030(3.t00089)
EDI: 
EDI_220060
ACAN: 
ACA1_079010
PFA: 
PF11_0370
PCB: 
PCHAS_071400(PC000427.01.0)
PBE: 
PB001092.02.0
PKN: 
PKH_093380
PVX: 
PVX_092410
PCY: 
PCYB_094180
TAN: 
TA18840
TPV: 
TP03_0656
TOT: 
TOT_030000211
BEQ: 
BEWA_053220
BBO: 
BBOV_III001830(17.m10668)
CPV: 
cgd2_1200
CHO: 
Chro.20132
TGO: 
TGME49_285240
TET: 
TTHERM_00401940
PTM: 
GSPATT00012181001 GSPATT00013728001
PTI: 
PHATRDRAFT_28009
FCY: 
FRACYDRAFT_186602
TPS: 
THAPSDRAFT_33911
AAF: 
AURANDRAFT_33417 AURANDRAFT_64002
PIF: 
PITG_04333
PSOJ: 
PHYSODRAFT_285961
SPAR: 
SPRG_07122
EHX: 
EMIHUDRAFT_56015
TBR: 
Tb927.3.1840(Tb03.30P12.550)
TCR: 
457251.10
LMA: 
LMJF_25_1770(EnCR)
LIF: 
LINJ_25_1850
LDO: 
LDBPK_251850
LMI: 
LMXM_25_1770
NGR: 
NAEGRDRAFT_83127
TVA: 
TVAG_231320
GLA: 
GL50803_88581
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kohlwein SD, Eder S, Oh CS, Martin CE, Gable K, Bacikova D, Dunn T
  Title
Tsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiae.
  Journal
Mol Cell Biol 21:109-25 (2001)
DOI:10.1128/MCB.21.1.109-125.2001
  Sequence
[sce:YDL015C]
Reference
  Authors
Gable K, Garton S, Napier JA, Dunn TM
  Title
Functional characterization of the Arabidopsis thaliana orthologue of Tsc13p, the enoyl reductase of the yeast microsomal fatty acid elongating system.
  Journal
J Exp Bot 55:543-5 (2004)
DOI:10.1093/jxb/erh061
  Sequence
[ath:AT3G55360]
Reference
PMID:12482854 (H.sapiens)
  Authors
Moon YA, Horton JD.
  Title
Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade.
  Journal
J Biol Chem 278:7335-43 (2003)
DOI:10.1074/jbc.M211684200
KEGG   ENZYME: 1.3.1.93Help
Entry
EC 1.3.1.93                 Enzyme                                 

Name
very-long-chain enoyl-CoA reductase;
TSC13 (gene name);
CER10 (gene name)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
very-long-chain acyl-CoA:NADP+ oxidoreductase
Reaction(IUBMB)
a very-long-chain acyl-CoA + NADP+ = a very-long-chain trans-2,3-dehydroacyl-CoA + NADPH + H+ [RN:R10828]
Reaction(KEGG)
R10828;
(other) R07761 R09449
Show
Substrate
very-long-chain acyl-CoA [CPD:C20876];
NADP+ [CPD:C00006]
Product
very-long-chain trans-2,3-dehydroacyl-CoA [CPD:C20879];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
This is the fourth component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. cf. EC 2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, and EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase.
History
EC 1.3.1.93 created 2012
Pathway
Fatty acid elongation
Biosynthesis of unsaturated fatty acids
Biosynthesis of secondary metabolites
Orthology
K10258  
very-long-chain enoyl-CoA reductase
Genes
HSA: 
9524(TECR)
PTR: 
455786(TECR)
PPS: 
100971383(TECR)
GGO: 
PON: 
NLE: 
100581652(TECR)
MCC: 
718928(TECR)
MCF: 
101926702(TECR)
CSAB: 
103234044(TECR)
RRO: 
104661039(TECR)
CJC: 
100402213(TECR)
SBQ: 
101033875(TECR)
MMU: 
106529(Tecr)
RNO: 
191576(Tecr)
CGE: 
100761652(Tecr)
NGI: 
103751841(Tecr)
HGL: 
101716060(Tecr)
CCAN: 
109686636(Tecr)
OCU: 
103346023(TECR)
TUP: 
102480210(TECR)
CFA: 
476687(TECR)
AML: 
100467030(TECR)
UMR: 
103682180(TECR)
FCA: 
101091601(TECR)
PTG: 
102948536 102959844(TECR)
AJU: 
106986213(TECR)
BTA: 
614105(TECR)
BOM: 
102285957(TECR)
BIU: 
109561491(TECR)
PHD: 
102340071(TECR)
CHX: 
102187120(TECR)
OAS: 
101117331(TECR)
SSC: 
100515709(TECR)
CFR: 
102519742(TECR)
BACU: 
102997227(TECR)
LVE: 
103070891(TECR)
ECB: 
100065024(TECR)
MYB: 
102260613(TECR)
MYD: 
102751823(TECR)
HAI: 
109394266(TECR)
RSS: 
109442713 109454938(TECR)
PALE: 
102887858(TECR)
LAV: 
100674918(TECR)
MDO: 
100026440(TECR) 100032861
SHR: 
100914010(TECR)
OAA: 
100080249 100081999(TECR)
GGA: 
424491(TECR)
MGP: 
100545685(TECR)
CJO: 
107307749(TECR) 107317393
APLA: 
101799511(TECR)
TGU: 
100230168(TECR)
GFR: 
102032504(TECR)
FAB: 
101810425(TECR) 101812411
PHI: 
102099600(TECR) 106628096
CCW: 
104695353(TECR)
FPG: 
101910412 101911436
FCH: 
102049843 106631266
AAM: 
106484788 106499774(TECR)
ASN: 
102370679(TECR) 102383204
AMJ: 
102559187(TECR) 102575131
PSS: 
102457301(TECR) 102459125
CMY: 
102929357(TECR) 102931932
CPIC: 
101937001(TECR) 101945886
ACS: 
100560578 100566730(tecr)
PBI: 
103058993 103065171(TECR)
GJA: 
107112228 107117643(TECR)
XLA: 
108713542 380153(gpsn2) 444160(tecr.L)
XTR: 
493561(tecr) 780081
DRE: 
326954(tecrb) 566085(tecra) 798606(tecrl2a)
IPU: 
100528865(tecr) 108255190 108256782 108280320
TRU: 
101061272 101070143(tecr) 101076261
TNG: 
GSTEN00016634G001 GSTEN00019764G001 GSTEN00026306G001
LCO: 
104918595 104923104 104925392(tecr) 109139143
MZE: 
101469805 101471785 101483996(tecr) 106675772
OLA: 
101155407(tecr) 101163495 101171706
XMA: 
102220976 102224233 102224945(tecr)
CSEM: 
103377076 103383916(tecr) 103392722
SASA: 
106564267(tecr) 106569794 106590656 106591668 106595986
LCM: 
102353704(TECR) 102356009 102357997
CMK: 
103174648 103191170(tecr)
BFO: 
BRAFLDRAFT_123019
CIN: 
100183960
SPU: 
576023
SKO: 
100372208 102804355
DME: 
Dmel_CG10849(Sc2)
DPO: 
Dpse_GA10597
DAN: 
Dana_GF24232
DER: 
Dere_GG15168
DPE: 
Dper_GL16056
DSE: 
Dsec_GM14597
DSI: 
Dsimw501_GD13786(Dsim_GD13786)
DWI: 
Dwil_GK15900 Dwil_GK16849
DYA: 
Dyak_GE21388
DGR: 
Dgri_GH15767
DMO: 
Dmoj_GI12546
DVI: 
Dvir_GJ16064
MDE: 
101887858
AGA: 
AgaP_AGAP010714
AAG: 
AaeL_AAEL008740
CQU: 
CpipJ_CPIJ005584
AME: 
725146
BIM: 
100747299
BTER: 
100644169
SOC: 
105193039
AEC: 
105153980
PBAR: 
105433004
HST: 
105181228
CFO: 
105259215
NVI: 
100113603 107980451
TCA: 
659815
BMOR: 
101742899
PXY: 
105385206
API: 
100160468
PHU: 
Phum_PHUM037790
DPX: 
DAPPUDRAFT_199063
ISC: 
IscW_ISCW002618
CEL: 
CELE_C15F1.6(art-1)
CBR: 
CBG11196(Cbr-art-1)
NAI: 
NECAME_05127
BMY: 
Bm1_42555
LOA: 
LOAG_03140
TSP: 
Tsp_07269
HRO: 
HELRODRAFT_155722
LGI: 
LOTGIDRAFT_232335
CRG: 
105326706
OBI: 
106878132
SMM: 
Smp_081820.3
OVI: 
T265_14517
NVE: 
NEMVE_v1g147144
ADF: 
107334908 107357184
TAD: 
TRIADDRAFT_29423
AQU: 
100640363
ATH: 
AT3G55360(CER10)
ALY: 
ARALYDRAFT_906954(ATTSC13)
CRB: 
CARUB_v10017686mg
EUS: 
EUTSA_v10010564mg EUTSA_v10014355mg
BRP: 
103841442 103846366
BNA: 
106354472 106372195 106396280(ECR) 106415464 106424766
THJ: 
104801897 104806959 104810019
CIT: 
102617880 102619239
CIC: 
CICLE_v100162851m CICLE_v10032183mg
TCC: 
18586099
GRA: 
105776424 105780559
GHI: 
107904734 107934412 107959873
EGR: 
104454293
GMX: 
100780327 100785393 100798454
PVU: 
PHAVU_004G094100g PHAVU_008G208700g
VRA: 
106762967 106763737 106767496
VAR: 
108337072 108344754 108345163
CCAJ: 
109795557 109817368
MTR: 
MTR_5g087590 MTR_6g037340 MTR_6g043740
CAM: 
101496420 101508101(sr5a)
ADU: 
107466595 107496735
AIP: 
107609317 107619734
LJA: 
Lj0g3v0067399.1(Lj0g3v0067399.1) Lj0g3v0067409.1(Lj0g3v0067409.1)
LANG: 
109336026 109356796 109361041 109361308
FVE: 
101304235 101304356 101313554
PPER: 
18784679
PMUM: 
103332647
MDM: 
103406406 103408877 103409522 103424086 103438771 103445586
PXB: 
103935366 103946101
ZJU: 
107413483
CSV: 
101209094 101213758
CMO: 
103498153
RCU: 
8267764 8285429
JCU: 
105647736
POP: 
POPTR_0008s01370g(POPTRDRAFT_765095) POPTR_0008s05550g(POPTRDRAFT_720621) POPTR_0010s21190g(POPTRDRAFT_822481) POPTR_0010s25150g(POPTRDRAFT_770744) POPTR_0010s25160g
VVI: 
100266766
SLY: 
101255353 101263911
SPEN: 
107003199 107020319
SOT: 
102581846 102599277 102600822
INI: 
109148160 109186449 109187162
SIND: 
105166561 105171911
BVG: 
104904012 104907190
NNU: 
104594555
OSA: 
4324516
DOSA: 
Os01t0150000-01(Os01g0150000)
OBR: 
102717286 102717451
BDI: 
100830422 100835261
ATS: 
F775_31011
ZMA: 
100191179(AY106269) 103633692
SITA: 
101781761 105914355
PDA: 
103696797 103703465
EGU: 
105036394 105052214
MUS: 
103969301 103987000
ATR: 
18421589 18436069
SMO: 
SELMODRAFT_186154 SELMODRAFT_270920
PPP: 
PHYPADRAFT_203665 PHYPADRAFT_57093 PHYPADRAFT_67731
CRE: 
CHLREDRAFT_602
VCN: 
VOLCADRAFT_72272
OLU: 
OSTLU_49170
OTA: 
Ot03g04010
BPG: 
Bathy07g01910
MIS: 
MICPUN_60190
MPP: 
MICPUCDRAFT_49391
CSL: 
COCSUDRAFT_36177
CVR: 
CHLNCDRAFT_20573
APRO: 
F751_1654
CME: 
CYME_CMD146C
CCP: 
CHC_T00008438001
SCE: 
YDL015C(TSC13)
AGO: 
AGOS_AER215W
ERC: 
Ecym_5259
KLA: 
KLLA0C04367g
LTH: 
KLTH0E15950g
VPO: 
Kpol_1010p67
ZRO: 
ZYRO0A05038g
CGR: 
CAGL0K01837g
NCS: 
NCAS_0I01880(NCAS0I01880)
NDI: 
NDAI_0A06480(NDAI0A06480)
TPF: 
TPHA_0A04340(TPHA0A04340)
TBL: 
TBLA_0B01660(TBLA0B01660)
TDL: 
TDEL_0D04380(TDEL0D04380)
KAF: 
KAFR_0F02320(KAFR0F02320)
PPA: 
PAS_chr4_0780
DHA: 
DEHA2B00968g
PIC: 
PICST_39084(TSC13)
PGU: 
PGUG_00050
SPAA: 
SPAPADRAFT_132798
LEL: 
LELG_01381 LELG_05600
CAL: 
CAALFM_C101050CA(CaO19.3293)
CTP: 
CTRG_04406
COT: 
CORT_0B08560 CORT_0B11210
CDU: 
CD36_00990
CTEN: 
CANTEDRAFT_108493
YLI: 
YALI0A04983g
CLU: 
CLUG_00022
CAUR: 
QG37_05093
NCR: 
NCU03362
NTE: 
NEUTE1DRAFT117529(NEUTE1DRAFT_117529)
SMP: 
SMAC_04071
PAN: 
PODANSg6420
TTT: 
THITE_2123364
MTM: 
MYCTH_2145474
CTHR: 
CTHT_0001860
MGR: 
MGG_03250
TMN: 
UCRPA7_5124
FGR: 
FGSG_00629
FPU: 
FPSE_06407
FVR: 
FVEG_00568
FOX: 
FOXG_00946
NHE: 
NECHADRAFT_98899
TRE: 
TRIREDRAFT_105035
MAW: 
MAC_05645
MAJ: 
MAA_01851
CMT: 
CCM_05177
VAL: 
VDBG_05577
VDA: 
VDAG_07519
CFJ: 
CFIO01_07269
ELA: 
UCREL1_8704
SSL: 
SS1G_10706
BFU: 
BC1G_04255
MBE: 
MBM_02606
PSCO: 
LY89DRAFT_737543
GLZ: 
GLAREA_03598
ANI: 
AN1968.2
AFM: 
AFUA_4G10760
AOR: 
AOR_1_156074(AO090038000096) AOR_1_2872154(AO090003001139)
ANG: 
ANI_1_968184(An04g05930)
AFV: 
AFLA_026780 AFLA_125740
ACT: 
ACLA_049930
NFI: 
NFIA_105330
PCS: 
Pc22g07000
PDP: 
PDIP_33130
CIM: 
CIMG_01478
CPW: 
CPC735_049630
PBL: 
PAAG_02630
PBN: 
PADG_01649
URE: 
UREG_05117
ABE: 
ARB_02271
TVE: 
TRV_04982
AJE: 
HCAG_01670
PNO: 
SNOG_07392
PTE: 
PTT_16464
BZE: 
COCCADRAFT_34894
BSC: 
COCSADRAFT_104969
BOR: 
COCMIDRAFT_101215
ZTR: 
MYCGRDRAFT_98769
PFJ: 
MYCFIDRAFT_76038
BCOM: 
BAUCODRAFT_34915
NPA: 
UCRNP2_7555
TML: 
GSTUM_00001911001
SPO: 
SPBC646.07c
CNE: 
CNE01780
CNB: 
CNBE1760
CGI: 
CGB_E2340W
TMS: 
TREMEDRAFT_71207
TVS: 
TRAVEDRAFT_126270
DSQ: 
DICSQDRAFT_166875
PCO: 
PHACADRAFT_89473
SHS: 
STEHIDRAFT_141777
HIR: 
HETIRDRAFT_54691
PSQ: 
PUNSTDRAFT_116689
ADL: 
AURDEDRAFT_105341 AURDEDRAFT_152816
FME: 
FOMMEDRAFT_102627
GTR: 
GLOTRDRAFT_78098
LBC: 
LACBIDRAFT_251245
MRR: 
Moror_17838
CCI: 
CC1G_10032
SCM: 
SCHCODRAFT_67919
CPUT: 
CONPUDRAFT_99121
SLA: 
SERLADRAFT_449601
WSE: 
WALSEDRAFT_66778
WIC: 
J056_002528
UMA: 
UMAG_03622
PFP: 
PFL1_02440
MGL: 
MGL_0166
PGR: 
PGTG_02971
MLR: 
MELLADRAFT_87292
DDI: 
DDB_G0270270(gpsn2)
DPP: 
DICPUDRAFT_52983
DFA: 
DFA_02956(gpsn2)
EHI: 
EHI_045030(3.t00089)
EDI: 
EDI_220060
ACAN: 
ACA1_079010
PFA: 
PF11_0370
PCB: 
PCHAS_071400(PC000427.01.0)
PBE: 
PB001092.02.0
PKN: 
PKH_093380
PVX: 
PVX_092410
PCY: 
PCYB_094180
TAN: 
TA18840
TPV: 
TP03_0656
TOT: 
TOT_030000211
BEQ: 
BEWA_053220
BBO: 
BBOV_III001830(17.m10668)
CPV: 
cgd2_1200
CHO: 
Chro.20132
TGO: 
TGME49_285240
TET: 
TTHERM_00401940
PTM: 
GSPATT00012181001 GSPATT00013728001
PTI: 
PHATRDRAFT_28009
FCY: 
FRACYDRAFT_186602
TPS: 
THAPSDRAFT_33911
AAF: 
AURANDRAFT_33417 AURANDRAFT_64002
PIF: 
PITG_04333
PSOJ: 
PHYSODRAFT_285961
SPAR: 
SPRG_07122
EHX: 
EMIHUDRAFT_56015
TBR: 
Tb927.3.1840(Tb03.30P12.550)
TCR: 
457251.10
LMA: 
LMJF_25_1770(EnCR)
LIF: 
LINJ_25_1850
LDO: 
LDBPK_251850
LMI: 
LMXM_25_1770
NGR: 
NAEGRDRAFT_83127
TVA: 
TVAG_231320
GLA: 
GL50803_88581
 » show all
Taxonomy
Reference
1  [PMID:11113186]
  Authors
Kohlwein SD, Eder S, Oh CS, Martin CE, Gable K, Bacikova D, Dunn T
  Title
Tsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiae.
  Journal
Mol. Cell. Biol. 21 (2001) 109-25.
  Sequence
[sce:YDL015C]
Reference
2  [PMID:14673020]
  Authors
Gable K, Garton S, Napier JA, Dunn TM
  Title
Functional characterization of the Arabidopsis thaliana orthologue of Tsc13p, the enoyl reductase of the yeast microsomal fatty acid elongating system.
  Journal
J. Exp. Bot. 55 (2004) 543-5.
  Sequence
[ath:AT3G55360]
Reference
3  [PMID:15958487]
  Authors
Kvam E, Gable K, Dunn TM, Goldfarb DS
  Title
Targeting of Tsc13p to nucleus-vacuole junctions: a role for very-long-chain fatty acids in the biogenesis of microautophagic vesicles.
  Journal
Mol. Biol. Cell. 16 (2005) 3987-98.
  Sequence
[sce:YDL015C]
Reference
4  [PMID:15829606]
  Authors
Zheng H, Rowland O, Kunst L
  Title
Disruptions of the Arabidopsis Enoyl-CoA reductase gene reveal an essential role  for very-long-chain fatty acid synthesis in cell expansion during plant morphogenesis.
  Journal
Plant. Cell. 17 (2005) 1467-81.
  Sequence
[ath:AT3G55360]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
KEGG   REACTION: R10828Help
Entry
R10828                      Reaction                               

Name
very-long-chain acyl-CoA:NADP+ oxidoreductase
Definition
Very-long-chain acyl-CoA + NADP+ <=> Very-long-chain trans-2,3-dehydroacyl-CoA + NADPH + H+
Equation
Comment
Elongation of C16/C18 acyl-CoAs to very-long-chain acyl CoAs.
Reaction class
C00005_C00006
C20876_C20879
Enzyme
Pathway
Fatty acid elongation
Biosynthesis of secondary metabolites
Module
M00415  
Fatty acid biosynthesis, elongation, endoplasmic reticulum
Orthology
K10258  
very-long-chain enoyl-CoA reductase [EC:1.3.1.93]
DBGET integrated database retrieval system