| Entry |
|
| Name |
glyceraldehyde-3-phosphate dehydrogenase (ferredoxin);
GAPOR;
glyceraldehyde-3-phosphate Fd oxidoreductase;
glyceraldehyde-3-phosphate ferredoxin reductase
|
| Class |
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With an iron-sulfur protein as acceptor
 |
| Sysname |
D-glyceraldehyde-3-phosphate:ferredoxin oxidoreductase
|
| Reaction(IUBMB) |
D-glyceraldehyde-3-phosphate + H2O + 2 oxidized ferredoxin = 3-phospho-D-glycerate + 2 H+ + 2 reduced ferredoxin [RN: R07159]
|
| Reaction(KEGG) |
|
| Substrate |
D-glyceraldehyde-3-phosphate;
H2O [CPD: C00001];
oxidized ferredoxin [CPD: C00139]
|
| Product |
|
| Comment |
Contains tungsten-molybdopterin and iron-sulfur clusters. This enzyme is thought to function in place of glyceralde-3-phosphate dehydrogenase and possibly phosphoglycerate kinase in the novel Embden-Meyerhof-type glycolytic pathway found in Pyrococcus furiosus [1]. It is specific for glyceraldehyde-3-phosphate.
|
| History |
EC 1.2.7.6 created 2003
|
| Pathway |
| Glycolysis / Gluconeogenesis | | Metabolic pathways | | Microbial metabolism in diverse environments |
|
| Orthology |
| glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) |
|
| Genes |
GUR: | | GSB: | | DOL: | | ATM: | | TAM: | | TOP: | | TCM: | | MJA: | | MFE: | | MVU: | | MFS: | | MIF: | | MJH: | | MIG: | | MMP: | | MMQ: | | MMX: | | MMZ: | | MMD: | | MMAK: | | MMAO: | | MAE: | | MVN: | | MVO: | | MOK: | | MEV: | | PHO: | | PAB: | | PFU: | | PFI: | | PYN: | | PYA: | | PYS: | | PYC: | | TKO: | | TON: | | TGA: | | TSI: | | TBA: | | THE: | | THA: | | THM: | | TLT: | | THS: | | TNU: | | TEU: | | TGY: | | THV: | | TCH: | | TPEP: | | PPAC: | | SMR: | | SHC: | | IHO: | | IIS: | | DKA: | | DFD: | | DMU: | | TAG: | | IAG: | | THG: | | PFM: | | PDL: | | PAI: | | PIS: | | PCL: | | PAS: | | PYR: | | POG: | | TNE: | | CMA: | | TUZ: | | TTN: | | VDI: | | VMO: | | ASC: | | CLG: | | NAA: | | » show all
 |
| Reference |
|
| Authors |
Mukund S, Adams MW. |
| Title |
Glyceraldehyde-3-phosphate ferredoxin oxidoreductase, a novel tungsten-containing enzyme with a potential glycolytic role in the hyperthermophilic archaeon Pyrococcus furiosus. |
| Journal |
J. Biol. Chem. 270 (1995) 8389-92. |
| Sequence |
|
| Reference |
|
| Authors |
Roy R, Menon AL, Adams MW. |
| Title |
Aldehyde oxidoreductases from Pyrococcus furiosus. |
| Journal |
Methods. Enzymol. 331 (2001) 132-44. |
| Sequence |
|
| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 162995-20-2 |