KEGG   ORTHOLOGY: K13403Help
Entry
K13403                      KO                                     
Name
MTHFD2
Definition
methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
Pathway
One carbon pool by folate
Module
M00141  
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    K13403  MTHFD2; methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase
KEGG pathway modules [BR:ko00002]
 Pathway module
  Nucleotide and amino acid metabolism
   Cofactor and vitamin biosynthesis
    M00141  C1-unit interconversion, eukaryotes
     K13403  MTHFD2; methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.15  methylenetetrahydrofolate dehydrogenase (NAD+)
     K13403  MTHFD2; methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     K13403  MTHFD2; methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase
BRITE hierarchy
Other DBs
Genes
HSA: 
10797(MTHFD2) 441024(MTHFD2L)
PTR: 
459331(MTHFD2) 461253(MTHFD2L)
PPS: 
100974548(MTHFD2L) 100994215(MTHFD2)
GGO: 
101139170(MTHFD2L)
PON: 
100442117(MTHFD2) 100445055(MTHFD2L)
MCC: 
702907(MTHFD2L)
MMU: 
17768(Mthfd2) 665563(Mthfd2l)
RNO: 
305248(Mthfd2l) 313410(RGD1564040) 680308(Mthfd2)
CFA: 
482197(MTHFD2L) 483107(MTHFD2)
AML: 
FCA: 
101083836(MTHFD2)
BTA: 
517539(MTHFD2) 536269(MTHFD2L)
SSC: 
100525706 100737806
ECB: 
100053990(MTHFD2) 100056425
MDO: 
100023851 100024210
SHR: 
100915702(MTHFD2L) 100917387(MTHFD2)
OAA: 
100081813
GGA: 
426126(MTHFD2) 770327(MTHFD2L)
MGP: 
100538988
TGU: 
100224318(MTHFD2L)
ACS: 
100553649 100566586
XLA: 
432317(mthfd2) 446641(mthfd2)
XTR: 
100170462(mthfd2) 100497864
DRE: 
100004977(mthfd2) 100331625
TRU: 
101073406
OLA: 
101160170 101165643
BFO: 
BRAFLDRAFT_62006
CIN: 
100186867
SPU: 
588966
DME: 
Dmel_CG18466(Nmdmc)
DPO: 
Dpse_GA14943
DAN: 
Dana_GF18431
DER: 
Dere_GG17397
DPE: 
Dper_GL12491
DSE: 
Dsec_GM26287
DSI: 
Dsim_GD20823
DWI: 
Dwil_GK14062
DYA: 
Dyak_GE24801
DGR: 
Dgri_GH18238
DMO: 
Dmoj_GI10194
DVI: 
Dvir_GJ23482
AGA: 
AgaP_AGAP004677
AAG: 
AaeL_AAEL014871
CQU: 
CpipJ_CPIJ004710
TCA: 
662099
API: 
100164363
PHU: 
Phum_PHUM125130
ISC: 
IscW_ISCW022040
CEL: 
CELE_K07E3.3(dao-3)
CBR: 
CBG16896(Cbr-dao-3)
TAD: 
TRIADDRAFT_50697
AQU: 
100640189
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8485162
  Authors
Price BD, Laughon A
  Title
The isolation and characterization of a Drosophila gene encoding a putative NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase.
  Journal
Biochim Biophys Acta 1173:94-8 (1993)
DBGET integrated database retrieval system