KEGG   ORTHOLOGY: K13997Help
Entry
K13997                      KO                                     
Name
PDHX
Definition
dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex
Pathway
Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Pyruvate metabolism
Module
M00307  
Pyruvate oxidation, pyruvate => acetyl-CoA
Disease
H00072  
Pyruvate dehydrogenase complex deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    K13997  PDHX; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex
   00020 Citrate cycle (TCA cycle)
    K13997  PDHX; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex
   00620 Pyruvate metabolism
    K13997  PDHX; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex
KEGG pathway modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Central carbohydrate metabolism
    M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
     K13997  PDHX; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex
BRITE hierarchy
Genes
HSA: 
8050(PDHX)
PTR: 
451120(PDHX)
PPS: 
100991366(PDHX)
GGO: 
101137782(PDHX)
PON: 
100455315(PDHX)
MCC: 
717932(PDHX)
MMU: 
27402(Pdhx)
RNO: 
311254(Pdhx)
CFA: 
475942(PDHX)
AML: 
100475970(PDHX)
FCA: 
101095373(PDHX)
BTA: 
517402(PDHX)
SSC: 
100525559
ECB: 
100059260(PDHX)
MDO: 
100031583(PDHX)
SHR: 
100929357
GGA: 
423154(PDHX)
MGP: 
100544023(PDHX)
TGU: 
100220979(PDHX)
XLA: 
447247(pdhx)
XTR: 
100379696(pdhx)
DRE: 
393532(pdhx)
TRU: 
101070208
OLA: 
101170510
BFO: 
BRAFLDRAFT_59834
CIN: 
100179052
SPU: 
577260
ISC: 
IscW_ISCW005143
NVE: 
NEMVE_v1g190464
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9242632
  Authors
Harris RA, Bowker-Kinley MM, Wu P, Jeng J, Popov KM
  Title
Dihydrolipoamide dehydrogenase-binding protein of the human pyruvate dehydrogenase complex. DNA-derived amino acid sequence, expression, and reconstitution of the pyruvate dehydrogenase complex.
  Journal
J Biol Chem 272:19746-51 (1997)
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