KEGG ORTHOLOGY: K14677

ORTHOLOGY: K14677

Entry

K14677 KO

Name

ACY1

Definition

aminoacylase [EC:3.5.1.14]

Pathway

ko00330

Arginine and proline metabolism

Module

M00028

Ornithine biosynthesis, glutamate => ornithine

Disease

H01146

Aminoacylase 1 deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Amino acid metabolism
   00330 Arginine and proline metabolism
    K14677  ACY1; aminoacylase
KEGG pathway modules [BR:ko00002]
Pathway module
  Nucleotide and amino acid metabolism
   Arginine and proline metabolism
    M00028  Ornithine biosynthesis, glutamate => ornithine
     K14677  ACY1; aminoacylase
Enzymes [BR:ko01000]
3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.14  aminoacylase
     K14677  ACY1; aminoacylase
Peptidases [BR:ko01002]
Metallo Peptidases
  Family M20
   K14677  ACY1; aminoacylase

Other DBs

RN:

R00669

GO:

0004046

Genes

HSA:	95(ACY1)
PTR:	460414(ACY1)
PPS:	100989711(ACY1)
GGO:	101146240
PON:	100171519(ACY1)
MCC:	698851(ABHD14A)
MMU:	109652(Acy1)
RNO:	300981(Acy1)
CFA:	476602(ACY1)
AML:	100479661
FCA:	101101118
BTA:	768058(ACY1)
SSC:	396930(ACY1)
ECB:	100060631(ACY1)
MDO:	100031141
SHR:	100934680
OAA:	100075293
GGA:	100858836
MGP:	100550404
TGU:	100219242(ACY1)
ACS:	100567123
XLA:	446741(acy1.1)
XTR:	496883(acy1.1)
DRE:	393970(acy1)
TRU:	101072726
OLA:	101160548
BFO:	BRAFLDRAFT_262219
CIN:	100185588
SPU:	578000
DME:	Dmel_CG6465 Dmel_CG6726
DPO:	Dpse_GA19815 Dpse_GA26984 Dpse_GA27068 Dpse_GA29129 Dpse_GA29130
DAN:	Dana_GF16975 Dana_GF17518 Dana_GF17519
DER:	Dere_GG11184 Dere_GG17281 Dere_GG17282
DPE:	Dper_GL13662 Dper_GL13663 Dper_GL23825 Dper_GL23826
DSE:	Dsec_GM26165 Dsec_GM26166 Dsec_GM26483
DSI:	Dsim_GD20716 Dsim_GD20717 Dsim_GD20996
DWI:	Dwil_GK14410 Dwil_GK22579 Dwil_GK22580
DYA:	Dyak_GE10351 Dyak_GE24682 Dyak_GE24683
DGR:	Dgri_GH11206 Dgri_GH23739 Dgri_GH23814 Dgri_GH23872
DMO:	Dmoj_GI18128 Dmoj_GI23017 Dmoj_GI23020
DVI:	Dvir_GJ17753 Dvir_GJ24611 Dvir_GJ24614
AGA:	AgaP_AGAP000679
AAG:	AaeL_AAEL011206
CQU:	CpipJ_CPIJ009804
AME:	408969
NVI:	100114283(NV16582)
TCA:	657672
API:	100162258 100169089
PHU:	Phum_PHUM047660
CEL:	CELE_C10C5.5(C10C5.5)
CBR:	CBG17687
TSP:	Tsp_07914
SMM:	Smp_019630
TAD:	TRIADDRAFT_50344
AQU:	100634447
ATH:	AT1G44820 AT4G38220
ALY:	ARALYDRAFT_327784 ARALYDRAFT_473822
GMX:	100783172
MTR:	MTR_1g038920 MTR_1g039010
CSV:	101213747
RCU:	RCOM_1565970
POP:	POPTR_721246
VVI:	100260562
OSA:	4340457
DOSA:	Os08t0511900-01(Os08g0511900)
BDI:	100839108
SBI:	SORBI_07g027550(SORBIDRAFT_07g027550)
ZMA:	100282205
SMO:	SELMODRAFT_120255 SELMODRAFT_406809
PPP:	PHYPADRAFT_207940
CME:	CMA011C
MBR:	MONBRDRAFT_32786
NGR:	NAEGRDRAFT_77264 NAEGRDRAFT_81120
DDI:	DDB_G0270562(acy1)
DPP:	DICPUDRAFT_53427
PTI:	PHATRDRAFT_15083
TPS:	THAPSDRAFT_15114
PIF:	PITG_00028 PITG_00029 PITG_02852

» show all

Reference

PMID:12933810

Authors

Lindner HA, Lunin VV, Alary A, Hecker R, Cygler M, Menard R

Title

Essential roles of zinc ligation and enzyme dimerization for catalysis in the aminoacylase-1/M20 family.

Journal

J Biol Chem 278:44496-504 (2003)

All links

Ontology (6)   
   KEGG BRITE (5)   
   GO (1)   
Pathway (1259)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1249)   
Disease (1)   
   KEGG DISEASE (1)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (445)   
   KEGG GENES (113)   
   KEGG DGENES (20)   
   KEGG EGENES (311)   
   KEGG MGENES (1)   
Protein sequence (88)   
   UniProt (88)   
Literature (1)   
   PubMed (1)   
All databases (1804)   

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