KEGG   ORTHOLOGY: K15404Help
Entry
K15404                      KO                                     

Name
K15404, CER1
Definition
aldehyde decarbonylase [EC:4.1.99.5]
Pathway
Cutin, suberine and wax biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00073 Cutin, suberine and wax biosynthesis
    K15404  K15404, CER1; aldehyde decarbonylase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.99  Other carbon-carbon lyases
    4.1.99.5  aldehyde oxygenase (deformylating)
     K15404  K15404, CER1; aldehyde decarbonylase
BRITE hierarchy
Other DBs
RN: 
GO: 
Genes
ATH: 
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
105773703 105774362 105779994 105779995 105792677
GHI: 
107900564 107948639 107954139 107960346 107961728 107962103 107962106
EGR: 
104430284 104430947 104431049 104441318 104441320 104441328 104442842 104442847 104442848 104442849 108959208
GMX: 
100790115 100805835 100818557 106798072 106798323
PVU: 
PHAVU_010G040500g PHAVU_010G040600g
VRA: 
106772969 106772995 106773669
VAR: 
108347155 108347177 108347190
CCAJ: 
109790836 109792954 109814131 109817909 109817915
MTR: 
MTR_4g054150 MTR_4g054290 MTR_7g090100 MTR_7g090120 MTR_7g090140 MTR_8g009560 MTR_8g009590
CAM: 
101507583 101508006 101514081 101514846
ADU: 
107472613 107472630 107494920
AIP: 
107605303 107610850 107618742 107618743
LJA: 
Lj1g3v4156050.1(Lj1g3v4156050.1) Lj3g3v0618210.1(Lj3g3v0618210.1) Lj3g3v0618250.1(Lj3g3v0618250.1) Lj4g3v1120540.1(Lj4g3v1120540.1)
LANG: 
109352187 109352216 109361171 109363612
FVE: 
101297683 101308477 101311999 101312286
PPER: 
18785414 18786441 18787082 18787499 18787644 18787718
PMUM: 
103331413 103331414 103331441 103331464 103344052
MDM: 
103401488 103406883 103417529 103420616 103424941 103428452 103433190 103438942 103438959
PXB: 
103929751 103929753 103929757 103932050 103932052 103965505 103965506
ZJU: 
107403676 107403677 107403679 107403682 107403845 107421712 107421713
CSV: 
101203441 101203691 101221193 101222843
CMO: 
103483417 103483418 103483426 103498990
RCU: 
8266676 8266677
JCU: 
105637254 105643380
POP: 
POPTR_0014s15050g POPTR_0014s15080g POPTR_0014s15110g POPTR_0014s17850g(POPTRDRAFT_732680)
VVI: 
100243849 100248835 100250668 100252221 100256874 100261967 100262701 100854413
SLY: 
101244624 101252060 101253677 101263099 101267647 101267934 101268663 109119791
SPEN: 
107005221 107005457 107008221 107008222 107014415 107014566 107025017
SOT: 
102579007 102579333 102579884 102593084 102595425 102595750 102599091 102599945
INI: 
109182241 109182254 109182262
SIND: 
105167221 105167251 105173435 105173436
BVG: 
104905209 104905211
NNU: 
104590840 104596252 104596253 104596254 104611270 104611276
OSA: 
4330012(OJ1234_B11.10)
DOSA: 
Os02t0621300-01(Os02g0621300) Os10t0471100-01(Os10g0471100)
OBR: 
102703957 102714431
BDI: 
100825208 100833295 100833807 100833914 100837949
ATS: 
F775_07504 F775_07505 F775_11907 F775_13611 F775_18018 F775_27980 F775_30254 F775_30507 F775_42817
SBI: 
8067437 8072487
ZMA: 
100273712(CER1) 100280261(cl3929_1)
SITA: 
101762753 101769789 101772770 101775794
PDA: 
103699030
EGU: 
105044200 105044255 105055747
MUS: 
103971700 103992720
ATR: 
18447308 18447310 18447313
SMO: 
SELMODRAFT_129942(CER1-2) SELMODRAFT_230422(CER1-1)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8718622
  Authors
Aarts MG, Keijzer CJ, Stiekema WJ, Pereira A
  Title
Molecular characterization of the CER1 gene of arabidopsis involved in epicuticular wax biosynthesis and pollen fertility.
  Journal
Plant Cell 7:2115-27 (1995)
DOI:10.1105/tpc.7.12.2115
  Sequence
[ath:AT1G02205]
KEGG   ENZYME: 4.1.99.5Help
Entry
EC 4.1.99.5                 Enzyme                                 

Name
aldehyde oxygenase (deformylating);
decarbonylase;
aldehyde decarbonylase;
octadecanal decarbonylase;
octadecanal alkane-lyase
Class
Lyases;
Carbon-carbon lyases;
Other carbon-carbon lyases
BRITE hierarchy
Sysname
a long-chain aldehyde alkane-lyase
Reaction(IUBMB)
a long-chain aldehyde + O2 + 2 NADPH + 2 H+ = an alkane + formate + H2O + 2 NADP+ [RN:R03728]
Reaction(KEGG)
R03728;
(other) R09466
Show
Substrate
long-chain aldehyde [CPD:C00609];
O2 [CPD:C00007];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Product
alkane [CPD:C01371];
formate [CPD:C00058];
H2O [CPD:C00001];
NADP+ [CPD:C00006]
Comment
Contains a diiron center. Involved in the biosynthesis of alkanes. The enzyme from the cyanobacterium Nostoc punctiforme PCC 73102 is only active in vitro in the presence of ferredoxin, ferredoxin reductase and NADPH, and produces mostly C15 and C17 alkanes [2,3]. The enzyme from pea (Pisum sativum) produces alkanes of chain length C18 to C32 and is inhibited by metal-chelating agents [1]. The substrate for this enzyme is formed by EC 1.2.1.80, acyl-[acyl-carrier protein] reductase.
History
EC 4.1.99.5 created 1989, modified 2011, modified 2013
Pathway
Cutin, suberine and wax biosynthesis
Biosynthesis of secondary metabolites
Orthology
K14331  
fatty aldehyde decarbonylase
K15404  
aldehyde decarbonylase
Genes
ATH: 
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
105773703 105774362 105779994 105779995 105792677
GHI: 
107900564 107948639 107954139 107960346 107961728 107962103 107962106
EGR: 
104430284 104430947 104431049 104441318 104441320 104441328 104442842 104442847 104442848 104442849 108959208
GMX: 
100790115 100805835 100818557 106798072 106798323
PVU: 
PHAVU_010G040500g PHAVU_010G040600g
VRA: 
106772969 106772995 106773669
VAR: 
108347155 108347177 108347190
CCAJ: 
109790836 109792954 109814131 109817909 109817915
MTR: 
MTR_4g054150 MTR_4g054290 MTR_7g090100 MTR_7g090120 MTR_7g090140 MTR_8g009560 MTR_8g009590
CAM: 
101507583 101508006 101514081 101514846
ADU: 
107472613 107472630 107494920
AIP: 
107605303 107610850 107618742 107618743
LJA: 
Lj1g3v4156050.1(Lj1g3v4156050.1) Lj3g3v0618210.1(Lj3g3v0618210.1) Lj3g3v0618250.1(Lj3g3v0618250.1) Lj4g3v1120540.1(Lj4g3v1120540.1)
LANG: 
109352187 109352216 109361171 109363612
FVE: 
101297683 101308477 101311999 101312286
PPER: 
18785414 18786441 18787082 18787499 18787644 18787718
PMUM: 
103331413 103331414 103331441 103331464 103344052
MDM: 
103401488 103406883 103417529 103420616 103424941 103428452 103433190 103438942 103438959
PXB: 
103929751 103929753 103929757 103932050 103932052 103965505 103965506
ZJU: 
107403676 107403677 107403679 107403682 107403845 107421712 107421713
CSV: 
101203441 101203691 101221193 101222843
CMO: 
103483417 103483418 103483426 103498990
RCU: 
8266676 8266677
JCU: 
105637254 105643380
POP: 
POPTR_0014s15050g POPTR_0014s15080g POPTR_0014s15110g POPTR_0014s17850g(POPTRDRAFT_732680)
VVI: 
100243849 100248835 100250668 100252221 100256874 100261967 100262701 100854413
SLY: 
101244624 101252060 101253677 101263099 101267647 101267934 101268663 109119791
SPEN: 
107005221 107005457 107008221 107008222 107014415 107014566 107025017
SOT: 
102579007 102579333 102579884 102593084 102595425 102595750 102599091 102599945
INI: 
109182241 109182254 109182262
SIND: 
105167221 105167251 105173435 105173436
BVG: 
104905209 104905211
NNU: 
104590840 104596252 104596253 104596254 104611270 104611276
OSA: 
4330012(OJ1234_B11.10)
DOSA: 
Os02t0621300-01(Os02g0621300) Os10t0471100-01(Os10g0471100)
OBR: 
102703957 102714431
BDI: 
100825208 100833295 100833807 100833914 100837949
ATS: 
F775_07504 F775_07505 F775_11907 F775_13611 F775_18018 F775_27980 F775_30254 F775_30507 F775_42817
SBI: 
8067437 8072487
ZMA: 
100273712(CER1) 100280261(cl3929_1)
SITA: 
101762753 101769789 101772770 101775794
PDA: 
103699030
EGU: 
105044200 105044255 105055747
MUS: 
103971700 103992720
ATR: 
18447308 18447310 18447313
SMO: 
SELMODRAFT_129942(CER1-2) SELMODRAFT_230422(CER1-1)
PPJ: 
RK21_05027
PBC: 
CD58_03975
SYN: 
sll0208
SYZ: 
MYO_122780
SYY: 
SYNGTS_2252(sll0208)
SYT: 
SYNGTI_2251(sll0208)
SYS: 
SYNPCCN_2250(sll0208)
SYQ: 
SYNPCCP_2250(sll0208)
SYJ: 
D082_05310
SYW: 
SYNW1738
SYC: 
syc0050_d
SYF: 
Synpcc7942_1593
SYD: 
Syncc9605_0728
SYE: 
Syncc9902_1635
SYG: 
sync_1990
SYR: 
SynRCC307_1586
SYX: 
SynWH7803_0654
CYA: 
CYA_0415
CYB: 
CYB_2442
SYNE: 
Syn6312_2280
SYNP: 
Syn7502_03278
SYNK: 
KR100_05365
SYNR: 
KR49_12745
SYND: 
KR52_13300
SYU: 
M744_09020
SYH: 
Syncc8109_1976
SYNW: 
SynWH8103_01989
TEL: 
tll1313
THN: 
NK55_03185
CGC: 
Cyagr_0039 Cyagr_1038
CYI: 
CBM981_0849
DSL: 
Dacsa_2178
CMP: 
Cha6605_4153
LEN: 
LEP3755_23570
LET: 
O77CONTIG1_03123
LBO: 
LBWT_14420
PSEU: 
Pse7367_3626
PMA: 
Pro_0532
PMM: 
PMM0532
PMT: 
PMT_1231
PMN: 
PMN2A_1863
PMI: 
PMT9312_0532
PMB: 
A9601_05881
PMC: 
P9515_05961
PMF: 
P9303_07791
PMG: 
P9301_05581
PMH: 
P9215_06131
PMJ: 
P9211_05351
PME: 
NATL1_05881
PRC: 
EW14_0578
PRM: 
EW15_0629
AMR: 
AM1_4041
MAR: 
MAE_53090
MPK: 
VL20_1523
CAN: 
Cyan10605_1692
HAO: 
PCC7418_0961
CYU: 
UCYN_05810
GLP: 
Glo7428_0150
GEE: 
GM3708_2118
CYT: 
cce_0778
CYP: 
PCC8801_0455
CYN: 
Cyan7425_0398
CYH: 
Cyan8802_0468
TER: 
Tery_2280
MIC: 
Mic7113_4535
ARP: 
NIES39_M01940
GEI: 
GEI7407_1564
OAC: 
Oscil6304_2075
ONI: 
Osc7112_0944
CEP: 
Cri9333_4418
GVI: 
gll3146
GLJ: 
GKIL_0725
ANA: 
alr5283
NPU: 
Npun_R1711
NOS: 
Nos7107_1028
NOP: 
Nos7524_4304
NON: 
NOS3756_54760
AVA: 
Ava_2533
ANB: 
ANA_C11210
ACY: 
Anacy_3389
AWA: 
AA650_00525
NAZ: 
Aazo_3371
CSG: 
Cylst_0697
CALO: 
Cal7507_5586
CALT: 
Cal6303_4369
CALH: 
IJ00_07390
RIV: 
Riv7116_3790
FIS: 
FIS3754_06310
NCN: 
BZZ01_14980
CTHE: 
Chro_1554
CEO: 
ETSB_0877
 » show all
Taxonomy
Reference
1  [PMID:6593720]
  Authors
Cheesbrough TM, Kolattukudy PE.
  Title
Alkane biosynthesis by decarbonylation of aldehydes catalyzed by a particulate preparation from Pisum sativum.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 81 (1984) 6613-7.
Reference
2  [PMID:20671186]
  Authors
Schirmer A, Rude MA, Li X, Popova E, del Cardayre SB
  Title
Microbial biosynthesis of alkanes.
  Journal
Science. 329 (2010) 559-62.
  Sequence
Reference
3  [PMID:21341652]
  Authors
Warui DM, Li N, Norgaard H, Krebs C, Bollinger JM Jr, Booker SJ
  Title
Detection of formate, rather than carbon monoxide, as the stoichiometric coproduct in conversion of fatty aldehydes to alkanes by a cyanobacterial aldehyde decarbonylase.
  Journal
J. Am. Chem. Soc. 133 (2011) 3316-9.
  Sequence
Reference
4  [PMID:22947199]
  Authors
Li N, Chang WC, Warui DM, Booker SJ, Krebs C, Bollinger JM Jr
  Title
Evidence for only oxygenative cleavage of aldehydes to alk(a/e)nes and formate by cyanobacterial aldehyde decarbonylases.
  Journal
Biochemistry. 51 (2012) 7908-16.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
94185-90-7
KEGG   REACTION: R09466Help
Entry
R09466                      Reaction                               

Name
aldehyde decarbonylase
Definition
Long-chain aldehyde <=> Alkane + CO
Equation
Enzyme
Pathway
Cutin, suberine and wax biosynthesis
Biosynthesis of secondary metabolites
Orthology
K15404  
aldehyde decarbonylase [EC:4.1.99.5]
DBGET integrated database retrieval system