KEGG ORTHOLOGY: K16044

ORTHOLOGY: K16044

Entry

K16044 KO

Name

iolW

Definition

scyllo-inositol 2-dehydrogenase (NADP+) [EC:1.1.1.371]

Pathway

ko00562

Inositol phosphate metabolism

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    K16044  iolW; scyllo-inositol 2-dehydrogenase (NADP+)
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.371  scyllo-inositol 2-dehydrogenase (NADP+)
     K16044  iolW; scyllo-inositol 2-dehydrogenase (NADP+)

Other DBs

RN:

R09954

COG:

COG0673

Genes

ETA:	ETA_17660(ydgJ)
EBI:	EbC_19670
PLU:	plu2375
PAY:	PAU_02122
PTT:	VY86_19370
PMR:	PMI1302
PMIB:	BB2000_1322
PVL:	AOB99_08470
XBO:	XBJ1_2311(ydgJ)
XBV:	XBW1_2060(ydgJ)
XNE:	XNC1_2319(ydgJ)
XNM:	XNC2_2237(ydgJ)
XDO:	XDD1_2185(ydgJ)
XPO:	XPG1_1694(ydgJ)
XHO:	A9255_05550
PSI:	S70_00355
PSX:	DR96_3217
PSTA:	BGK56_03330
PRG:	RB151_023040(ydgJ)
MMK:	MU9_2251
LRZ:	BJI69_12265
VHR:	AL538_14985
VEJ:	VEJY3_08950
AMH:	I633_20085
AMAA:	amad1_19150
AMAL:	I607_18140
AMAE:	I876_18515
AMAO:	I634_18280
AMAD:	I636_18295
AMAI:	I635_19140
AMAG:	I533_18210
AMAC:	MASE_18545
AMB:	AMBAS45_18785
AMG:	AMEC673_18525
AMK:	AMBLS11_17785
CEB:	B0D95_01555
HCH:	HCH_04874
CCX:	COCOR_03600(ydgJ)
SUR:	STAUR_3951
SCL:	sce9140
SCU:	SCE1572_51645
PSF:	PSE_1871
AZL:	AZL_a07880
ALI:	AZOLI_p10392
ABF:	AMK58_28225
ATI:	AL072_22855
BSU:	BSU33530(yvaA)
BSR:	I33_3473
BSL:	A7A1_2571
BSH:	BSU6051_33530(yvaA)
BSY:	I653_16240
BSUT:	BSUB_03581(iolW)
BSUL:	BSUA_03581(iolW)
BSUS:	Q433_18400
BSS:	BSUW23_16430(yvaA)
BST:	GYO_3666
BSO:	BSNT_09872(yvaA)
BSN:	BSn5_07685
BSQ:	B657_33530(yvaA)
BSX:	C663_3223(yvaA)
BSP:	U712_16785
BLI:	BL00819(yvaA)
BLD:	BLi03572(yvaA)
BLH:	BaLi_c36330(yvaA)
BAY:	RBAM_030710(yvaA)
BAQ:	BACAU_3096(yvaA)
BYA:	BANAU_3261(yvaA)
BAMP:	B938_15725
BAML:	BAM5036_2984(yvaA)
BAMA:	RBAU_3203(yvaA)
BAMN:	BASU_2989(yvaA)
BAMB:	BAPNAU_3268(yvaA)
BAMT:	AJ82_17360
BAMY:	V529_33330(yvaA)
BMP:	NG74_03240(yvaA)
BAO:	BAMF_3201(yvaA)
BAZ:	BAMTA208_17000(yvaA)
BQL:	LL3_03484
BXH:	BAXH7_03471(yvaA)
BQY:	MUS_3672(yvaA)
BAMI:	KSO_003795
BAMC:	U471_31860
BAMF:	U722_16505
BAE:	BATR1942_14725
BATR:	TD68_13740
BAN:	BA_3655
BAR:	GBAA_3655
BAT:	BAS3390
BAH:	BAMEG_0977
BAI:	BAA_3684
BAX:	H9401_3476
BANT:	A16_36620
BANR:	A16R_37060
BANS:	BAPAT_3499
BANH:	HYU01_17865
BANV:	DJ46_2371
BCE:	BC3595
BCA:	BCE_3615
BCZ:	BCE33L3302
BCR:	BCAH187_A3622
BCB:	BCB4264_A3704
BCU:	BCAH820_3606
BCG:	BCG9842_B1611
BCQ:	BCQ_3389
BCX:	BCA_3688
BAL:	BACI_c35410
BNC:	BCN_3405
BCF:	bcf_17825
BCER:	BCK_17270
BCEF:	BcrFT9_02745
BCY:	Bcer98_2245
BTK:	BT9727_3353
BTL:	BALH_3235
BTB:	BMB171_C3270
BTT:	HD73_3870
BTHR:	YBT1520_19110
BTHI:	BTK_19040
BTC:	CT43_CH3543
BTF:	YBT020_17615
BTM:	MC28_2745
BTG:	BTB_c36760
BTI:	BTG_01370
BTN:	BTF1_16030
BTHT:	H175_ch3601
BTHU:	YBT1518_19750
BTW:	BF38_4773
BTHY:	AQ980_11975
BWE:	BcerKBAB4_3283
BWW:	bwei_1360
BTY:	Btoyo_0807
BMYC:	DJ92_562
BMYO:	BG05_2434
BMQ:	BMQ_2694
BMD:	BMD_2681
BMH:	BMWSH_2518(yvaA)
BMEG:	BG04_5160
BJS:	MY9_3401
BACP:	SB24_13380
BACB:	OY17_18680
BBY:	CY96_16965
BACY:	QF06_15110
BACL:	BS34A_36590(yvaA)
BALM:	BsLM_3363
BEO:	BEH_16135
BSJ:	UP17_10730
BGY:	BGLY_3959(yvaA)
BGI:	BGM20_10900
EAN:	Eab7_0194 Eab7_2550
EXM:	U719_01045 U719_14975
EXU:	ESP131_00620 ESP131_03480
BLR:	BRLA_c003300(yvaA)
PJD:	Pjdr2_5119
GYM:	GYMC10_6003
PLV:	ERIC2_c06120(yvaA)
PAEQ:	R50912_31105
PBJ:	VN24_08645
CST:	CLOST_0537(ydgJ)
PUF:	UFO1_3455
APN:	Asphe3_34530
SLR:	L21SP2_0785
DORI:	FH5T_21230
BBD:	Belba_0642
ALM:	AO498_03670
FIB:	A6C57_21895

» show all

Reference

PMID:20133360

Authors

Morinaga T, Ashida H, Yoshida K

Title

Identification of two scyllo-inositol dehydrogenases in Bacillus subtilis.

Journal

Microbiology 156:1538-46 (2010)
DOI:10.1099/mic.0.037499-0

Sequence

[bsu:BSU33530]

All links

Ontology (3)   
   KEGG BRITE (2)   
   COG (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (183)   
   KEGG GENES (167)   
   RefGene (2)   
   EGENES (6)   
   OC (8)   
Protein sequence (98)   
   UniProt (97)   
   SWISS-PROT (1)   
Literature (1)   
   PubMed (1)   
All databases (292)   

Download RDF

ENZYME: 1.1.1.371

Entry

EC 1.1.1.371 Enzyme

Name

scyllo-inositol 2-dehydrogenase (NADP+);
iolW (gene name)

Class

Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor

Sysname

scyllo-inositol:NADP+ 2-oxidoreductase

Reaction(IUBMB)

scyllo-inositol + NADP+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADPH + H+ [RN:R09954]

Reaction(KEGG)

R09954

Substrate

scyllo-inositol [CPD:C06153];
NADP+ [CPD:C00006]

Product

2,4,6/3,5-pentahydroxycyclohexanone [CPD:C00691];
NADPH [CPD:C00005];
H+ [CPD:C00080]

Comment

The enzyme, found in the bacterium Bacillus subtilis, has no activity with NAD+ [cf. EC 1.1.1.370, scyllo-inositol 2-dehydrogenase (NAD+)].

History

EC 1.1.1.371 created 2014

Pathway

ec00562	Inositol phosphate metabolism
ec01120	Microbial metabolism in diverse environments

Orthology

K16044

scyllo-inositol 2-dehydrogenase (NADP+)

Genes

ETA:	ETA_17660(ydgJ)
EBI:	EbC_19670
PLU:	plu2375
PAY:	PAU_02122
PTT:	VY86_19370
PMR:	PMI1302
PMIB:	BB2000_1322
PVL:	AOB99_08470
XBO:	XBJ1_2311(ydgJ)
XBV:	XBW1_2060(ydgJ)
XNE:	XNC1_2319(ydgJ)
XNM:	XNC2_2237(ydgJ)
XDO:	XDD1_2185(ydgJ)
XPO:	XPG1_1694(ydgJ)
XHO:	A9255_05550
PSI:	S70_00355
PSX:	DR96_3217
PSTA:	BGK56_03330
PRG:	RB151_023040(ydgJ)
MMK:	MU9_2251
LRZ:	BJI69_12265
VHR:	AL538_14985
VEJ:	VEJY3_08950
AMH:	I633_20085
AMAA:	amad1_19150
AMAL:	I607_18140
AMAE:	I876_18515
AMAO:	I634_18280
AMAD:	I636_18295
AMAI:	I635_19140
AMAG:	I533_18210
AMAC:	MASE_18545
AMB:	AMBAS45_18785
AMG:	AMEC673_18525
AMK:	AMBLS11_17785
CEB:	B0D95_01555
HCH:	HCH_04874
CCX:	COCOR_03600(ydgJ)
SUR:	STAUR_3951
SCL:	sce9140
SCU:	SCE1572_51645
PSF:	PSE_1871
AZL:	AZL_a07880
ALI:	AZOLI_p10392
ABF:	AMK58_28225
ATI:	AL072_22855
BSU:	BSU33530(yvaA)
BSR:	I33_3473
BSL:	A7A1_2571
BSH:	BSU6051_33530(yvaA)
BSY:	I653_16240
BSUT:	BSUB_03581(iolW)
BSUL:	BSUA_03581(iolW)
BSUS:	Q433_18400
BSS:	BSUW23_16430(yvaA)
BST:	GYO_3666
BSO:	BSNT_09872(yvaA)
BSN:	BSn5_07685
BSQ:	B657_33530(yvaA)
BSX:	C663_3223(yvaA)
BSP:	U712_16785
BLI:	BL00819(yvaA)
BLD:	BLi03572(yvaA)
BLH:	BaLi_c36330(yvaA)
BAY:	RBAM_030710(yvaA)
BAQ:	BACAU_3096(yvaA)
BYA:	BANAU_3261(yvaA)
BAMP:	B938_15725
BAML:	BAM5036_2984(yvaA)
BAMA:	RBAU_3203(yvaA)
BAMN:	BASU_2989(yvaA)
BAMB:	BAPNAU_3268(yvaA)
BAMT:	AJ82_17360
BAMY:	V529_33330(yvaA)
BMP:	NG74_03240(yvaA)
BAO:	BAMF_3201(yvaA)
BAZ:	BAMTA208_17000(yvaA)
BQL:	LL3_03484
BXH:	BAXH7_03471(yvaA)
BQY:	MUS_3672(yvaA)
BAMI:	KSO_003795
BAMC:	U471_31860
BAMF:	U722_16505
BAE:	BATR1942_14725
BATR:	TD68_13740
BAN:	BA_3655
BAR:	GBAA_3655
BAT:	BAS3390
BAH:	BAMEG_0977
BAI:	BAA_3684
BAX:	H9401_3476
BANT:	A16_36620
BANR:	A16R_37060
BANS:	BAPAT_3499
BANH:	HYU01_17865
BANV:	DJ46_2371
BCE:	BC3595
BCA:	BCE_3615
BCZ:	BCE33L3302
BCR:	BCAH187_A3622
BCB:	BCB4264_A3704
BCU:	BCAH820_3606
BCG:	BCG9842_B1611
BCQ:	BCQ_3389
BCX:	BCA_3688
BAL:	BACI_c35410
BNC:	BCN_3405
BCF:	bcf_17825
BCER:	BCK_17270
BCEF:	BcrFT9_02745
BCY:	Bcer98_2245
BTK:	BT9727_3353
BTL:	BALH_3235
BTB:	BMB171_C3270
BTT:	HD73_3870
BTHR:	YBT1520_19110
BTHI:	BTK_19040
BTC:	CT43_CH3543
BTF:	YBT020_17615
BTM:	MC28_2745
BTG:	BTB_c36760
BTI:	BTG_01370
BTN:	BTF1_16030
BTHT:	H175_ch3601
BTHU:	YBT1518_19750
BTW:	BF38_4773
BTHY:	AQ980_11975
BWE:	BcerKBAB4_3283
BWW:	bwei_1360
BTY:	Btoyo_0807
BMYC:	DJ92_562
BMYO:	BG05_2434
BMQ:	BMQ_2694
BMD:	BMD_2681
BMH:	BMWSH_2518(yvaA)
BMEG:	BG04_5160
BJS:	MY9_3401
BACP:	SB24_13380
BACB:	OY17_18680
BBY:	CY96_16965
BACY:	QF06_15110
BACL:	BS34A_36590(yvaA)
BALM:	BsLM_3363
BEO:	BEH_16135
BSJ:	UP17_10730
BGY:	BGLY_3959(yvaA)
BGI:	BGM20_10900
EAN:	Eab7_0194 Eab7_2550
EXM:	U719_01045 U719_14975
EXU:	ESP131_00620 ESP131_03480
BLR:	BRLA_c003300(yvaA)
PJD:	Pjdr2_5119
GYM:	GYMC10_6003
PLV:	ERIC2_c06120(yvaA)
PAEQ:	R50912_31105
PBJ:	VN24_08645
CST:	CLOST_0537(ydgJ)
PUF:	UFO1_3455
APN:	Asphe3_34530
SLR:	L21SP2_0785
DORI:	FH5T_21230
BBD:	Belba_0642
ALM:	AO498_03670
FIB:	A6C57_21895

» show all

Reference

1 [PMID:20133360]

Authors

Morinaga T, Ashida H, Yoshida K.

Title

Identification of two scyllo-inositol dehydrogenases in Bacillus subtilis.

Journal

Microbiology. 156 (2010) 1538-46.

Sequence

[bsu:BSU33530]

Other DBs

ExplorEnz - The Enzyme Database:

1.1.1.371

IUBMB Enzyme Nomenclature:

1.1.1.371

ExPASy - ENZYME nomenclature database:

1.1.1.371

BRENDA, the Enzyme Database:

1.1.1.371

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (176)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (167)   
   RefGene (2)   
   EGENES (6)   
Protein sequence (33)   
   UniProt (31)   
   SWISS-PROT (2)   
DNA sequence (55)   
   GenBank (28)   
   EMBL (27)   
All databases (275)   

Download RDF

REACTION: R09954

Entry

R09954 Reaction

Name

scyllo-inositol:NADP+ oxidoreductase

Definition

scyllo-Inositol + NADP+ <=> 2,4,6/3,5-Pentahydroxycyclohexanone + NADPH + H+

Equation

C06153 + C00006 <=> C00691 + C00005 + C00080

Reaction class

RC00001	C00005_C00006
RC00182	C00691_C06153

Enzyme

1.1.1.371

Pathway

rn00562	Inositol phosphate metabolism
rn01120	Microbial metabolism in diverse environments

Orthology

K16044

scyllo-inositol 2-dehydrogenase (NADP+) [EC:1.1.1.371]

Other DBs

RHEA:

39066

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (168)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (167)   
All databases (181)   

Download RDF

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