KEGG   ORTHOLOGY: K18256Help
Entry
K18256                      KO                                     

Name
phtC
Definition
3,4-dihydroxyphthalate decarboxylase [EC:4.1.1.69]
Pathway
Polycyclic aromatic hydrocarbon degradation
Module
M00636  
Phthalate degradation, phthalate => protocatechuate
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Xenobiotics biodegradation and metabolism
   00624 Polycyclic aromatic hydrocarbon degradation
    K18256  phtC; 3,4-dihydroxyphthalate decarboxylase
KEGG modules [BR:ko00002]
 Pathway module
  Secondary metabolism
   Aromatics degradation
    M00636  Phthalate degradation, phthalate => protocatechuate
     K18256  phtC; 3,4-dihydroxyphthalate decarboxylase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.69  3,4-dihydroxyphthalate decarboxylase
     K18256  phtC; 3,4-dihydroxyphthalate decarboxylase
BRITE hierarchy
Other DBs
RN: 
GO: 
Genes
MVA: 
MGI: 
MSP: 
MMC: 
MKM: 
MJL: 
MRH: 
TaxonomyKoalaUniProt
Reference
  Authors
Stingley RL, Khan AA, Cerniglia CE.
  Title
Molecular characterization of a phenanthrene degradation pathway in Mycobacterium vanbaalenii PYR-1.
  Journal
Biochem Biophys Res Commun 322:133-46 (2004)
DOI:10.1016/j.bbrc.2004.07.089
Reference
  Authors
Pagnout C, Frache G, Poupin P, Maunit B, Muller JF, Ferard JF.
  Title
Isolation and characterization of a gene cluster involved in PAH degradation in Mycobacterium sp. strain SNP11: expression in Mycobacterium smegmatis mc(2)155.
  Journal
Res Microbiol 158:175-86 (2007)
DOI:10.1016/j.resmic.2006.11.002
  Sequence
[mva:Mvan_0543]
KEGG   ENZYME: 4.1.1.69Help
Entry
EC 4.1.1.69                 Enzyme                                 

Name
3,4-dihydroxyphthalate decarboxylase;
3,4-dihydroxyphthalate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname
3,4-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)
Reaction(IUBMB)
3,4-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2 [RN:R01634]
Reaction(KEGG)
Substrate
3,4-dihydroxyphthalate [CPD:C03223]
Product
3,4-dihydroxybenzoate [CPD:C00230];
CO2 [CPD:C00011]
History
EC 4.1.1.69 created 1986
Pathway
Polycyclic aromatic hydrocarbon degradation
Microbial metabolism in diverse environments
Orthology
K18256  
3,4-dihydroxyphthalate decarboxylase
Genes
MVA: 
MGI: 
MSP: 
MMC: 
MKM: 
MJL: 
MRH: 
Taxonomy
Reference
1  [PMID:7085570]
  Authors
Eaton RW, Ribbons DW.
  Title
Metabolism of dibutylphthalate and phthalate by Micrococcus sp. strain 12B.
  Journal
J. Bacteriol. 151 (1982) 48-57.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
83137-76-2
KEGG   REACTION: R01634Help
Entry
R01634                      Reaction                               

Name
3,4-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)
Definition
3,4-Dihydroxyphthalate <=> 3,4-Dihydroxybenzoate + CO2
Equation
Reaction class
C00230_C03223
Enzyme
Pathway
Polycyclic aromatic hydrocarbon degradation
Microbial metabolism in diverse environments
Module
M00636  
Phthalate degradation, phthalate => protocatechuate
Orthology
K18256  
3,4-dihydroxyphthalate decarboxylase [EC:4.1.1.69]
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