KEGG   ORTHOLOGY: K19629Help
Entry
K19629                      KO                                     

Name
tsaD1
Definition
4-(hydroxymethyl)benzenesulfonate dehydrogenase [EC:1.1.1.257]
Pathway
Toluene degradation
Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Xenobiotics biodegradation and metabolism
   00623 Toluene degradation
    K19629  tsaD1; 4-(hydroxymethyl)benzenesulfonate dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.257  4-(hydroxymethyl)benzenesulfonate dehydrogenase
     K19629  tsaD1; 4-(hydroxymethyl)benzenesulfonate dehydrogenase
BRITE hierarchy
Other DBs
RN: 
GO: 
Genes
AG: 
AAC44808(tsaD1)
TaxonomyKoalaUniProt
Reference
PMID:8828208
  Authors
Junker F, Saller E, Schlafli Oppenberg HR, Kroneck PM, Leisinger T, Cook AM
  Title
Degradative pathways for p-toluenecarboxylate and p-toluenesulfonate and their multicomponent oxygenases in Comamonas testosteroni strains PSB-4 and T-2.
  Journal
Microbiology 142 ( Pt 9):2419-27 (1996)
DOI:10.1099/00221287-142-9-2419
  Sequence

KEGG   ENZYME: 1.1.1.257Help
Entry
EC 1.1.1.257                Enzyme                                 

Name
4-(hydroxymethyl)benzenesulfonate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
4-(hydroxymethyl)benzenesulfonate:NAD+ oxidoreductase
Reaction(IUBMB)
4-(hydroxymethyl)benzenesulfonate + NAD+ = 4-formylbenzenesulfonate + NADH + H+ [RN:R05271]
Reaction(KEGG)
Substrate
4-(hydroxymethyl)benzenesulfonate [CPD:C06678];
NAD+ [CPD:C00003]
Product
4-formylbenzenesulfonate [CPD:C06679];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the toluene-4-sulfonate degradation pathway in Comamonas testosteroni.
History
EC 1.1.1.257 created 2000
Pathway
Toluene degradation
Microbial metabolism in diverse environments
Orthology
K19629  
4-(hydroxymethyl)benzenesulfonate dehydrogenase
Reference
1  [PMID:8828208]
  Authors
Junker F, Saller E, Schlafli Oppenberg HR, Kroneck PM, Leisinger T, Cook AM.
  Title
Degradative pathways for p-toluenecarboxylate and p-toluenesulfonate and their multicomponent oxygenases in Comamonas testosteroni strains PSB-4 and T-2.
  Journal
Microbiology. 142 ( Pt 9) (1996) 2419-27.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
167973-64-0

KEGG   REACTION: R05271Help
Entry
R05271                      Reaction                               

Name
4-(hydroxymethyl)benzenesulfonate:NAD+ oxidoreductase
Definition
4-Sulfobenzyl alcohol + NAD+ <=> 4-Sulfobenzaldehyde + NADH + H+
Equation
Reaction class
C00003_C00004
C06678_C06679
Enzyme
Pathway
Toluene degradation
Microbial metabolism in diverse environments
Degradation of aromatic compounds
Orthology
K19629  
4-(hydroxymethyl)benzenesulfonate dehydrogenase [EC:1.1.1.257]
Other DBs
RHEA: 

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