KEGG   ORTHOLOGY: K20142Help
Entry
K20142                      KO                                     

Name
IDOLDH
Definition
ipsdienol dehydrogenase [EC:1.1.1.386]
Pathway
Monoterpenoid biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Metabolism of terpenoids and polyketides
   00902 Monoterpenoid biosynthesis
    K20142  IDOLDH; ipsdienol dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.386  ipsdienol dehydrogenase
     K20142  IDOLDH; ipsdienol dehydrogenase
BRITE hierarchy
Other DBs
Genes
AG: 
AEQ59233(IDOLDH)
TaxonomyKoalaUniProt
Reference
  Authors
Figueroa-Teran R, Welch WH, Blomquist GJ, Tittiger C
  Title
Ipsdienol dehydrogenase (IDOLDH): a novel oxidoreductase important for Ips pini pheromone production.
  Journal
Insect Biochem Mol Biol 42:81-90 (2012)
DOI:10.1016/j.ibmb.2011.10.009
  Sequence

KEGG   ENZYME: 1.1.1.386Help
Entry
EC 1.1.1.386                Enzyme                                 

Name
ipsdienol dehydrogenase;
IDOLDH
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(R)-ipsdienol:NAD(P)+ oxidoreductase
Reaction(IUBMB)
(R)-ipsdienol + NAD(P)+ = ipsdienone + NAD(P)H + H+ [RN:R10918 R10919]
Reaction(KEGG)
Substrate
(R)-ipsdienol [CPD:C20943];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
ipsdienone [CPD:C20944];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme is involved in pheromone production by the pine engraver beetle, Ips pini.
History
EC 1.1.1.386 created 2015
Pathway
Monoterpenoid biosynthesis
Biosynthesis of secondary metabolites
Orthology
K20142  
ipsdienol dehydrogenase
Reference
1  [PMID:22101251]
  Authors
Figueroa-Teran R, Welch WH, Blomquist GJ, Tittiger C
  Title
Ipsdienol dehydrogenase (IDOLDH): a novel oxidoreductase important for Ips pini pheromone production.
  Journal
Insect. Biochem. Mol. Biol. 42 (2012) 81-90.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
KEGG   REACTION: R10918Help
Entry
R10918                      Reaction                               

Name
(R)-ipsdienol:NAD+ oxidoreductase
Definition
(R)-Ipsdienol + NAD+ <=> Ipsdienone + NADH + H+
Equation
Comment
NADP+ (see R10919)
Reaction class
C00003_C00004
C20943_C20944
Enzyme
Pathway
Monoterpenoid biosynthesis
Biosynthesis of secondary metabolites
Orthology
K20142  
ipsdienol dehydrogenase [EC:1.1.1.386]
KEGG   REACTION: R10919Help
Entry
R10919                      Reaction                               

Name
(R)-ipsdienol:NADP+ oxidoreductase
Definition
(R)-Ipsdienol + NADP+ <=> Ipsdienone + NADPH + H+
Equation
Comment
NAD+ (see R10918)
Reaction class
C00005_C00006
C20943_C20944
Enzyme
Pathway
Monoterpenoid biosynthesis
Biosynthesis of secondary metabolites
Orthology
K20142  
ipsdienol dehydrogenase [EC:1.1.1.386]
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